| alpha1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation. | α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
Wang H, Cui X, Wang L, Fan N, Yu M, Qin H, Liu S, Yan Q., Free PMC Article | 11/1/2023 |
| Genome-wide CRISPR/Cas9 screening identifies a targetable MEST-PURA interaction in cancer metastasis. | Genome-wide CRISPR/Cas9 screening identifies a targetable MEST-PURA interaction in cancer metastasis.
Xu WW, Liao L, Dai W, Zheng CC, Tan XP, He Y, Zhang QH, Huang ZH, Chen WY, Qin YR, Chen KS, He ML, Law S, Lung ML, He QY, Li B., Free PMC Article | 06/21/2023 |
| MiR-29c-3p represses gastric cancer development via modulating MEST. | MiR-29c-3p represses gastric cancer development via modulating MEST.
Li H, Lv J, Wang J, Wang H, Luo L. | 05/4/2023 |
| Human umbilical cord blood mesenchymal stem cells-derived exosomal microRNA-503-3p inhibits progression of human endometrial cancer cells through downregulating MEST. | Human umbilical cord blood mesenchymal stem cells-derived exosomal microRNA-503-3p inhibits progression of human endometrial cancer cells through downregulating MEST.
Pan Y, Wang X, Li Y, Yan P, Zhang H. | 08/27/2022 |
| Increased co-expression of MEST and BRCA1 is associated with worse prognosis and immune infiltration in ovarian cancer. | Increased co-expression of MEST and BRCA1 is associated with worse prognosis and immune infiltration in ovarian cancer.
Zhang J, Yu S, Li Q, Wang Q, Zhang J. | 04/30/2022 |
| miR-145-5p Modulates Gefitinib Resistance by Targeting NRAS and MEST in Non-Small Cell Lung Cancer. | miR-145-5p Modulates Gefitinib Resistance by Targeting NRAS and MEST in Non-Small Cell Lung Cancer.
Yu C, Li B, Wang J, Zhang Z, Li S, Lei S, Wang Q. | 02/12/2022 |
| MEST promotes lung cancer invasion and metastasis by interacting with VCP to activate NF-kappaB signaling. | MEST promotes lung cancer invasion and metastasis by interacting with VCP to activate NF-κB signaling.
Wang Y, Zhang J, Li YJ, Yu NN, Liu WT, Liang JZ, Xu WW, Sun ZH, Li B, He QY., Free PMC Article | 02/5/2022 |
| Hypermethylation of Mest promoter causes aberrant Wnt signaling in patients with Alzheimer's disease. | Hypermethylation of Mest promoter causes aberrant Wnt signaling in patients with Alzheimer's disease.
Prasad R, Jung H, Tan A, Song Y, Moon S, Shaker MR, Sun W, Lee J, Ryu H, Lim HK, Jho EH., Free PMC Article | 01/29/2022 |
| The effect of folic acid deficiency on Mest/Peg1 in neural tube defects. | The effect of folic acid deficiency on Mest/Peg1 in neural tube defects.
Chang S, Jing J, Shangguan S, Li B, Yao X, Liu X, Zhang T, Wu J, Wang L. | 11/13/2021 |
| The sperm epigenome does not display recurrent epimutations in patients with severely impaired spermatogenesis. | The sperm epigenome does not display recurrent epimutations in patients with severely impaired spermatogenesis.
Leitão E, Di Persio S, Laurentino S, Wöste M, Dugas M, Kliesch S, Neuhaus N, Horsthemke B., Free PMC Article | 06/5/2021 |
| MEST induces Twist-1-mediated EMT through STAT3 activation in breast cancers. | MEST induces Twist-1-mediated EMT through STAT3 activation in breast cancers.
Kim MS, Lee HS, Kim YJ, Lee DY, Kang SG, Jin W., Free PMC Article | 10/3/2020 |
| Long intergenic noncoding RNA (LINC00) 284 (LINC00284) is involved in angiogenesis during ovarian cancer (OC) development by recruiting nuclear factor kappa B (NF-kappaB1) and down-regulating mesoderm-specific transcript (MEST). | Long intergenic noncoding RNA LINC00284 knockdown reduces angiogenesis in ovarian cancer cells via up-regulation of MEST through NF-κB1.
Ruan Z, Zhao D., Free PMC Article | 06/13/2020 |
| Imprinting methylation in SNRPN and MEST1 in adult blood predicts cognitive ability. | Imprinting methylation in SNRPN and MEST1 in adult blood predicts cognitive ability.
Lorgen-Ritchie M, Murray AD, Ferguson-Smith AC, Richards M, Horgan GW, Phillips LH, Hoad G, Gall I, Harrison K, McNeill G, Ito M, Haggarty P., Free PMC Article | 11/9/2019 |
| Study provides evidence that MEST mediates the impact of prenatal bisphenol A exposure on long-term body weight development in offspring by triggering adipocyte differentiation. | MEST mediates the impact of prenatal bisphenol A exposure on long-term body weight development.
Junge KM, Leppert B, Jahreis S, Wissenbach DK, Feltens R, Grützmann K, Thürmann L, Bauer T, Ishaque N, Schick M, Bewerunge-Hudler M, Röder S, Bauer M, Schulz A, Borte M, Landgraf K, Körner A, Kiess W, von Bergen M, Stangl GI, Trump S, Eils R, Polte T, Lehmann I., Free PMC Article | 05/25/2019 |
| We conclude methylation changes at some CpG sites of MEST and DLK differentially methylated regions in preeclamptic group | Alteration in methylation level at differential methylated regions of MEST and DLK1 in fetus of preeclampsia.
Wang X, Wan L, Weng X, Xie J, Zhang A, Liu Y, Dong M. | 09/1/2018 |
| Some growth-regulating imprinted genes such as MEST and MEG3, are susceptible to non-imprinted allele during development and differentiation, whereas the intergenic differentially methylated region of others (i.e. PEG3) are strictly maintained. | Hypermethylation of the non-imprinted maternal MEG3 and paternal MEST alleles is highly variable among normal individuals.
Haertle L, Maierhofer A, Böck J, Lehnen H, Böttcher Y, Blüher M, Schorsch M, Potabattula R, El Hajj N, Appenzeller S, Haaf T., Free PMC Article | 10/21/2017 |
| strongly expressed in invasive extravillous trophoblasts during the first trimester | DNA methylation-associated repression of MEST/PEG1 expression contributes to the invasion of extravillous trophoblast cells.
Peng W, Chen Y, Luo X, Shan N, Lan X, Olson D, Zhang H, Ding YB, Qi HB. | 10/14/2017 |
| G4 formation at motifs not previously identified through bioinformatic analysis of the MEST promoter, is reported. | Structural Analysis of G-Quadruplex Formation at the Human MEST Promoter.
Stevens AJ, Kennedy MA., Free PMC Article | 08/12/2017 |
| altered DNA methylation at imprinted domains including IGF2/H19 and PEG1/MEST may mediate the association between human papillomavirus infection and invasive cervical cancer | PEG1/MEST and IGF2 DNA methylation in CIN and in cervical cancer.
Vidal AC, Henry NM, Murphy SK, Oneko O, Nye M, Bartlett JA, Overcash F, Huang Z, Wang F, Mlay P, Obure J, Smith J, Vasquez B, Swai B, Hernandez B, Hoyo C., Free PMC Article | 10/11/2014 |
| The expression levels of miR-335 significantly correlated with those of MEST, supporting the notion that the intronic miR-335 is co-expressed with its host gene | Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma.
Dohi O, Yasui K, Gen Y, Takada H, Endo M, Tsuji K, Konishi C, Yamada N, Mitsuyoshi H, Yagi N, Naito Y, Tanaka S, Arii S, Yoshikawa T., Free PMC Article | 01/11/2014 |
| DNA methylation level at the H19 and MEST differentially methylated regions (DMRs)is reduced in placentas from pregnancies conceived by IVF/ICSI when compared with placentas from spontaneous conception. | Placentas from pregnancies conceived by IVF/ICSI have a reduced DNA methylation level at the H19 and MEST differentially methylated regions.
Nelissen EC, Dumoulin JC, Daunay A, Evers JL, Tost J, van Montfoort AP. | 09/28/2013 |
| Paternal methylation aberrations at imprinting control regions of DLK1-GTL2, MEST (PEG1), and ZAC (PLAGL1) and global methylation levels are not associated with idiopathic recurrent spontaneous miscarriages. | Methylation status of imprinted genes DLK1-GTL2, MEST (PEG1), ZAC (PLAGL1), and LINE-1 elements in spermatozoa of normozoospermic men, unlike H19 imprinting control regions, is not associated with idiopathic recurrent spontaneous miscarriages.
Ankolkar M, Salvi V, Warke H, Vundinti BR, Balasinor NH. | 07/6/2013 |
| These results support the idea that intrauterine exposure to gestational diabetes mellitus has long-lasting effects on the epigenome of the offspring. | Metabolic programming of MEST DNA methylation by intrauterine exposure to gestational diabetes mellitus.
El Hajj N, Pliushch G, Schneider E, Dittrich M, Müller T, Korenkov M, Aretz M, Zechner U, Lehnen H, Haaf T., Free PMC Article | 05/25/2013 |
| Data indicate that ARMCX2, COL1A1, MDK, MEST and MLH1 genes acquired methylation in drug-resistant ovarian cancer-sustaining (side population) cells. | Candidate DNA methylation drivers of acquired cisplatin resistance in ovarian cancer identified by methylome and expression profiling.
Zeller C, Dai W, Steele NL, Siddiq A, Walley AJ, Wilhelm-Benartzi CS, Rizzo S, van der Zee A, Plumb JA, Brown R. | 01/26/2013 |
| MEST showed tissue-specific imprinting, being paternally expressed in skeletal muscle, fat, pituitary gland, heart, kidney, lung, stomach and uterus, and maternally expressed in spleen and liver. | Conservation of genomic imprinting at the NDN, MAGEL2 and MEST loci in pigs.
Zhang FW, Han ZB, Deng CY, He HJ, Wu Q. | 09/8/2012 |