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    MMP14 matrix metallopeptidase 14 [ Homo sapiens (human) ]

    Gene ID: 4323, updated on 2-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Association of MMP3, MMP14, and MMP25 gene polymorphisms with cerebral stroke risk: a case-control study.

    Association of MMP3, MMP14, and MMP25 gene polymorphisms with cerebral stroke risk: a case-control study.
    Yin Y, Zhang Y, Zhang X, Zhang Q, Wang J, Yang T, Liang C, Li W, Liu J, Ma X, Duan J, Shi W, Tian Y., Free PMC Article

    11/22/2023
    Expression of MMP-14 and its role in bone destruction in middle ear cholesteatoma: A prospective observational study.

    Expression of MMP-14 and its role in bone destruction in middle ear cholesteatoma: A prospective observational study.
    Lei Y, An J, Ren Q, Wang M, Gao M., Free PMC Article

    11/1/2023
    KIF16B drives MT1-MMP recycling in macrophages and promotes co-invasion of cancer cells.

    KIF16B drives MT1-MMP recycling in macrophages and promotes co-invasion of cancer cells.
    Hey S, Wiesner C, Barcelona B, Linder S., Free PMC Article

    09/28/2023
    Gallbladder cancer-associated genetic variants rs1003349 and rs1004030 regulate MMP14 expression by altering SOX10- and MYB-binding sites.

    Gallbladder cancer-associated genetic variants rs1003349 and rs1004030 regulate MMP14 expression by altering SOX10- and MYB-binding sites.
    J V, Palo A, Besra K, Dixit M.

    07/12/2023
    Degradomic Identification of Membrane Type 1-Matrix Metalloproteinase as an ADAMTS9 and ADAMTS20 Substrate.

    Degradomic Identification of Membrane Type 1-Matrix Metalloproteinase as an ADAMTS9 and ADAMTS20 Substrate.
    Nandadasa S, Martin D, Deshpande G, Robert KL, Stack MS, Itoh Y, Apte SS., Free PMC Article

    06/30/2023
    Characterizing the function-related specific assembly pattern of matrix metalloproteinase-14 by dSTORM imaging.

    Characterizing the function-related specific assembly pattern of matrix metalloproteinase-14 by dSTORM imaging.
    Ge D, Chen J, Zhao Z, Sui B, Liang F, Wang H.

    06/1/2023
    ALIX promotes cell migration and invasion of head and neck squamous cell carcinoma by regulating the expression of MMP9, MMP14, VEGF-C.

    ALIX promotes cell migration and invasion of head and neck squamous cell carcinoma by regulating the expression of MMP9, MMP14, VEGF-C.
    Xie QH, Wang WM, Yang JG, Xia HF, Xiao BL, Chen GH, Huang J, Li RF, Chen G.

    05/17/2023
    Tumour Suppressor Neuron Navigator 3 and Matrix Metalloproteinase 14 are Co-expressed in Most Melanomas but Downregulated in Thick Tumours.

    Tumour Suppressor Neuron Navigator 3 and Matrix Metalloproteinase 14 are Co-expressed in Most Melanomas but Downregulated in Thick Tumours.
    Bugaeva O, Maliniemi P, Prestvik WS, Leivo E, Kluger N, Salava A, Virtanen S, Jäntti K, Saksela O, Lehti K, Kujala P, Krohn K, Ranki A., Free PMC Article

    03/10/2023
    MMP14 expression levels accurately predict the presence of extranodal extensions in oral squamous cell carcinoma: a retrospective cohort study.

    MMP14 expression levels accurately predict the presence of extranodal extensions in oral squamous cell carcinoma: a retrospective cohort study.
    Noda Y, Ishida M, Yamaka R, Ueno Y, Sakagami T, Fujisawa T, Iwai H, Tsuta K., Free PMC Article

    02/25/2023
    MT1-MMP and ADAM10/17 exhibit a remarkable overlap of shedding properties.

    MT1-MMP and ADAM10/17 exhibit a remarkable overlap of shedding properties.
    Werny L, Grogro A, Bickenbach K, Bülck C, Armbrust F, Koudelka T, Pathak K, Scharfenberg F, Sammel M, Sheikhouny F, Tholey A, Linder S, Becker-Pauly C.

    01/14/2023
    Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2.

    Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2.
    Guo X, Cao J, Cai JP, Wu J, Huang J, Asthana P, Wong SKK, Ye ZW, Gurung S, Zhang Y, Wang S, Wang Z, Ge X, Kwan HY, Lyu A, Chan KM, Wong N, Huang J, Zhou Z, Bian ZX, Yuan S, Wong HLX., Free PMC Article

    01/11/2023
    MT1-MMP Expression Levels and Catalytic Functions Dictate LDL Receptor-Related Protein-1 Ligand Internalization Capacity in U87 Glioblastoma Cells.

    MT1-MMP Expression Levels and Catalytic Functions Dictate LDL Receptor-Related Protein-1 Ligand Internalization Capacity in U87 Glioblastoma Cells.
    Pratt J, Haidara K, Annabi B., Free PMC Article

    12/10/2022
    [Matrix metalloproteinase 14 and plasma kallikrein 1 may be potential biomarkers in the diagnosis and treatment of sepsis: a proteomics and bioinformatics analysis].

    [Matrix metalloproteinase 14 and plasma kallikrein 1 may be potential biomarkers in the diagnosis and treatment of sepsis: a proteomics and bioinformatics analysis].
    Feng L, Liu Y, Chen M, Hu Y.

    10/1/2022
    Novel Roles of MT1-MMP and MMP-2: Beyond the Extracellular Milieu.

    Novel Roles of MT1-MMP and MMP-2: Beyond the Extracellular Milieu.
    Maybee DV, Ink NL, Ali MAM., Free PMC Article

    10/1/2022
    Endothelial cells induce degradation of ECM through enhanced secretion of MMP14 carried on extracellular vesicles in venous malformation.

    Endothelial cells induce degradation of ECM through enhanced secretion of MMP14 carried on extracellular vesicles in venous malformation.
    Chen GH, Yang JG, Xia HF, Zhang LZ, Chen YH, Wang KM, Duan X, Wu LZ, Zhao YF, Chen G.

    09/17/2022
    Endoglin and MMP14 Contribute to Ewing Sarcoma Spreading by Modulation of Cell-Matrix Interactions.

    Endoglin and MMP14 Contribute to Ewing Sarcoma Spreading by Modulation of Cell-Matrix Interactions.
    Puerto-Camacho P, Díaz-Martín J, Olmedo-Pelayo J, Bolado-Carrancio A, Salguero-Aranda C, Jordán-Pérez C, Esteban-Medina M, Álamo-Álvarez I, Delgado-Bellido D, Lobo-Selma L, Dopazo J, Sastre A, Alonso J, Grünewald TGP, Bernabeu C, Byron A, Brunton VG, Amaral AT, de Álava E., Free PMC Article

    08/27/2022
    M2-phenotype tumour-associated macrophages upregulate the expression of prognostic predictors MMP14 and INHBA in pancreatic cancer.

    M2-phenotype tumour-associated macrophages upregulate the expression of prognostic predictors MMP14 and INHBA in pancreatic cancer.
    Liang ZW, Yu J, Gu DM, Liu XM, Liu J, Wu MY, Xu MD, Shen M, Duan W, Li W., Free PMC Article

    07/23/2022
    Regulation of age-associated insulin resistance by MT1-MMP-mediated cleavage of insulin receptor.

    Regulation of age-associated insulin resistance by MT1-MMP-mediated cleavage of insulin receptor.
    Guo X, Asthana P, Gurung S, Zhang S, Wong SKK, Fallah S, Chow CFW, Che S, Zhai L, Wang Z, Ge X, Jiang Z, Wu J, Zhang Y, Wu X, Xu K, Lin CY, Kwan HY, Lyu A, Zhou Z, Bian ZX, Wong HLX., Free PMC Article

    07/9/2022
    The Role of Functional Polymorphisms in the Extracellular Matrix Modulation-Related Genes on Dupuytren's Contracture.

    The Role of Functional Polymorphisms in the Extracellular Matrix Modulation-Related Genes on Dupuytren's Contracture.
    Samulenas G, Insodaite R, Kunceviciene E, Poceviciute R, Masionyte L, Zitkeviciute U, Pilipaityte L, Smalinskiene A., Free PMC Article

    07/2/2022
    Activation of the GTPase ARF6 regulates invasion of human vascular smooth muscle cells by stimulating MMP14 activity.

    Activation of the GTPase ARF6 regulates invasion of human vascular smooth muscle cells by stimulating MMP14 activity.
    Fiola-Masson E, Artigalas J, Campbell S, Claing A., Free PMC Article

    06/18/2022
    Changes in the expression of membrane type-matrix metalloproteinases genes (MMP14, MMP15, MMP16, MMP24) during treatment and their potential impact on the survival of patients with non-small cell lung cancer (NSCLC).

    Changes in the expression of membrane type-matrix metalloproteinases genes (MMP14, MMP15, MMP16, MMP24) during treatment and their potential impact on the survival of patients with non-small cell lung cancer (NSCLC).
    Pietrzak J, Szmajda-Krygier D, Wosiak A, Świechowski R, Michalska K, Mirowski M, Żebrowska-Nawrocka M, Łochowski M, Balcerczak E.

    03/19/2022
    Comprehensive Analysis of the Immune and Prognostic Implication of MMP14 in Lung Cancer.

    Comprehensive Analysis of the Immune and Prognostic Implication of MMP14 in Lung Cancer.
    Zheng CL, Lu Q, Zhang N, Jing PY, Zhang JP, Wang WP, Li GZ., Free PMC Article

    03/12/2022
    Urine peptidome in combination with transcriptomics analysis highlights MMP7, MMP14 and PCSK5 for further investigation in chronic kidney disease.

    Urine peptidome in combination with transcriptomics analysis highlights MMP7, MMP14 and PCSK5 for further investigation in chronic kidney disease.
    Petra E, Siwy J, Vlahou A, Jankowski J., Free PMC Article

    02/26/2022
    Increased airway epithelial cell-derived exosomes activate macrophage-mediated allergic inflammation via CD100 shedding.

    Increased airway epithelial cell-derived exosomes activate macrophage-mediated allergic inflammation via CD100 shedding.
    Yu Y, Zhou Y, Di C, Zhao C, Chen J, Su W, Wu Q, Wu M, Su X, Xia Z., Free PMC Article

    02/26/2022
    A muscle cell-macrophage axis involving matrix metalloproteinase 14 facilitates extracellular matrix remodeling with mechanical loading.

    A muscle cell-macrophage axis involving matrix metalloproteinase 14 facilitates extracellular matrix remodeling with mechanical loading.
    Peck BD, Murach KA, Walton RG, Simmons AJ, Long DE, Kosmac K, Dungan CM, Kern PA, Bamman MM, Peterson CA., Free PMC Article

    02/19/2022
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