| The Organization of Pericentromeric Heterochromatin in Polytene Chromosome 3 of the Drosophilamelanogaster Line with the Rif1(1); SuUR(ES) Su(var)3-9(06) Mutations Suppressing Underreplication. | The Organization of Pericentromeric Heterochromatin in Polytene Chromosome 3 of the Drosophilamelanogaster Line with the Rif1(1); SuUR(ES) Su(var)3-9(06) Mutations Suppressing Underreplication.
Zykova T, Maltseva M, Goncharov F, Boldyreva L, Pokholkova G, Kolesnikova T, Zhimulev I., Free PMC Article | 01/15/2022 |
| Recruitment of either HP1(GAL4DBD) or SUUR(GAL4DBD) resulted in delayed completion of replication | Tethering of SUUR and HP1 proteins results in delayed replication of euchromatic regions in Drosophila melanogaster polytene chromosomes.
Pokholkova GV, Koryakov DE, Pindyurin AV, Kozhevnikova EN, Belyakin SN, Andreyenkov OV, Belyaeva ES, Zhimulev IF. | 03/5/2016 |
| SUUR protein binding correlates with gene regulation and specific chromatin types. | Developmental variation of the SUUR protein binding correlates with gene regulation and specific chromatin types in D. melanogaster.
Maksimov DA, Koryakov DE, Belyakin SN. | 01/10/2015 |
| Our findings support the idea that the effect of SUUR on replication elongation depends on the cell cycle stage and can be mediated through its physical interaction with replication fork. | Drosophila SUUR protein associates with PCNA and binds chromatin in a cell cycle-dependent manner.
Kolesnikova TD, Posukh OV, Andreyeva EN, Bebyakina DS, Ivankin AV, Zhimulev IF. | 09/7/2013 |
| the SUUR protein is required for the SU(VAR)3-9 enzyme to bind to the salivary gland polytene chromosomes | The SUUR protein is involved in binding of SU(VAR)3-9 and methylation of H3K9 and H3K27 in chromosomes of Drosophila melanogaster.
Koryakov DE, Walther M, Ebert A, Lein S, Zhimulev IF, Reuter G. | 09/3/2011 |
| Mutation of two conserved amino acid residues in this region impairs binding of SUUR to polytene chromosomes and reduces the ability of the protein to cause DNA underreplication. | Conservation of domain structure in a fast-evolving heterochromatic SUUR protein in drosophilids.
Yurlova AA, Makunin IV, Kolesnikova TD, Posukh OV, Belyaeva ES, Zhimulev IF., Free PMC Article | 02/1/2010 |
| Suppressor of Underreplication gene does not directely affect the replication progression | The mutation of the Suppressor of Underreplication gene does not affect the replication fork rate in the Drosophila melanogaster salivary gland polytene chromosomes.
Kolesnikova TD, Demakov SA, Ivankin AV, Andreenkova NG, Zhimulev IF. | 01/21/2010 |
| Reversible decondensation of heterochromatin regions of polytene chromosomes during ectopic expression of the SuUR gene. | Reversible decondensation of heterochromatin regions of Drosophila melanogaster polytene chromosomes during ectopic expression of the SuUR gene.
Kokoza EB, Kolesnikova TD, Zykov IA, Belyaeva ES, Zhimulev IF. | 01/21/2010 |
| it is proposed that interaction of SUUR with HP1 is crucial for the association of SUUR with chromatin | Interaction between the Drosophila heterochromatin proteins SUUR and HP1.
Pindyurin AV, Boldyreva LV, Shloma VV, Kolesnikova TD, Pokholkova GV, Andreyeva EN, Kozhevnikova EN, Ivanoschuk IG, Zarutskaya EA, Demakov SA, Gorchakov AA, Belyaeva ES, Zhimulev IF. | 01/21/2010 |
| these results suggest that SUUR is a ubiquitous marker of heterochromatin in different cell types | SUUR joins separate subsets of PcG, HP1 and B-type lamin targets in Drosophila.
Pindyurin AV, Moorman C, de Wit E, Belyakin SN, Belyaeva ES, Christophides GK, Kafatos FC, van Steensel B, Zhimulev IF. | 01/21/2010 |
| describe how, in double mutants for Suppressor of variegation 3-9 and SuUR genes encoding two structural proteins of heterochromatin, new banded heterochromatic segments appear in all polytene chromosomes | High-resolution analysis of Drosophila heterochromatin organization using SuUR Su(var)3-9 double mutants.
Andreyeva EN, Kolesnikova TD, Demakova OV, Mendez-Lago M, Pokholkova GV, Belyaeva ES, Rossi F, Dimitri P, Villasante A, Zhimulev IF., Free PMC Article | 01/21/2010 |
| SuUR mutation leads to earlier completion of DNA replication | Influence of the SuUR gene on intercalary heterochromatin in Drosophila melanogaster polytene chromosomes.
Zhimulev IF, Belyaeva ES, Makunin IV, Pirrotta V, Volkova EI, Alekseyenko AA, Andreyeva EN, Makarevich GF, Boldyreva LV, Nanayev RA, Demakova OV. | 01/21/2010 |
| The SuUR gene affects the distribution of HP1 and SU(VAR)3-9 on the nurse cell poytene chromosomes. | The SuUR gene influences the distribution of heterochromatic proteins HP1 and SU(VAR)3-9 on nurse cell polytene chromosomes of Drosophila melanogaster.
Koryakov DE, Reuter G, Dimitri P, Zhimulev IF. | 01/21/2010 |
| SuUR binds specificialy to boundary regions and regular distribution of boundary regions in chromosomes may represent the dispersion of sites designed for chromosomal silencing | SuUR protein binds to the boundary regions separating forum domains in Drosophila melanogaster.
Tchurikov NA, Kretova OV, Chernov BK, Golova YB, Zhimulev IF, Zykov IA. | 01/21/2010 |
| microdissection and sequence analysis of its pericentric heterochromatin | Microdissection and sequence analysis of pericentric heterochromatin from the Drosophila melanogastermutant Suppressor of Underreplication.
Moshkin YM, Belyakin SN, Rubtsov NB, Kokoza EB, Alekseyenko AA, Volkova EI, Belyaeva ES, Makunin IV, Spierer P, Zhimulev IF. | 01/21/2010 |
| Differential responses of polyploid and diploid cells to ectopic SuUR may reflect differences in the mechanisms underlying mitotic cell cycles and endocycles | Ectopic expression of the Suppressor of Underreplication gene inhibits endocycles but not the mitotic cell cycle in Drosophila melanogaster.
Volkova EI, Yurlova AA, Kolesnikova TD, Makunin IV, Zhimulev IF. | 01/21/2010 |
| Data on the SuUR gene, its expression, and effect on polytene chromosome structure and replication are summarized. | [Contribution of the SuUR gene to the organization of epigenetically repressed regions of Drosophila melanogaster chromosomes].
Kolesnikova TD, Andreeva EN, Pindiurin AV, Anan'ko NG, Beliakin SN, Shloma VV, Iurlova AA, Makunin IV, Pokholkova GV, Volkova EI, Zarutskaia EA, Kokoza EB, Seneshin VF, Beliaeva ES, Zhimulev IF. | 01/21/2010 |
| SUUR has at least two separate chromosome-binding regions that are able to recognize intercalary and pericentric heterochromatin specifically. | Functional dissection of the Suppressor of UnderReplication protein of Drosophila melanogaster: identification of domains influencing chromosome binding and DNA replication.
Kolesnikova TD, Makunin IV, Volkova EI, Pirrotta V, Belyaeva ES, Zhimulev IF. | 01/21/2010 |