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    MYD88 MYD88 innate immune signal transduction adaptor [ Homo sapiens (human) ]

    Gene ID: 4615, updated on 11-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Suppression of MALAT1 promotes human synovial mesenchymal stem cells enhance chondrogenic differentiation and prevent osteoarthritis of the knee in a rat model via regulating miR-212-5p/MyD88 axis.

    Suppression of MALAT1 promotes human synovial mesenchymal stem cells enhance chondrogenic differentiation and prevent osteoarthritis of the knee in a rat model via regulating miR-212-5p/MyD88 axis.
    Gao Z, Guo C, Xiang S, Zhang H, Wang Y, Xu H.

    03/1/2024
    Clinical, biological, electrophysiological and therapeutic profile of patients with anti-MAG neuropathy according to MYD88[L265P] and CXCR4 mutations and underlying haemopathy.

    Clinical, biological, electrophysiological and therapeutic profile of patients with anti-MAG neuropathy according to MYD88(L265P) and CXCR4 mutations and underlying haemopathy.
    Guérémy A, Boucraut J, Boudjarane J, Grapperon AM, Fortanier E, Farnault L, Gabert J, Vely F, Lacroix R, Kouton L, Attarian S, Delmont E.

    02/28/2024
    The impact of MYD88 and PIM1 in mature large B-cell non-Hodgkin lymphomas: Defining element of their evolution and prognosis.

    The impact of MYD88 and PIM1 in mature large B-cell non-Hodgkin lymphomas: Defining element of their evolution and prognosis.
    Cristian M, Așchie M, Mitroi AF, Deacu M, Boșoteanu M, Bălțătescu GI, Stoica AG, Nicolau AA, Enciu M, Crețu AM, Caloian AD, Orășanu CI, Poinăreanu I., Free PMC Article

    02/27/2024
    Role of the MyD88 Dependent Pathway in Degenerative Disc Disease.

    Role of the MyD88 Dependent Pathway in Degenerative Disc Disease.
    Akgun MY, Akyol S, Ozlen F, Alizada O, Cetintas SC, Turk O, Hanci M.

    11/1/2023
    Thalidomide Alleviates Apoptosis, Oxidative Damage and Inflammation Induced by Pemphigus Vulgaris IgG in HaCat Cells and Neonatal Mice Through MyD88.

    Thalidomide Alleviates Apoptosis, Oxidative Damage and Inflammation Induced by Pemphigus Vulgaris IgG in HaCat Cells and Neonatal Mice Through MyD88.
    Luan C, Lu Z, Chen J, Chen M, Zhao R, Li X., Free PMC Article

    09/28/2023
    Paralog-specific signaling by IRAK1/4 maintains MyD88-independent functions in MDS/AML.

    Paralog-specific signaling by IRAK1/4 maintains MyD88-independent functions in MDS/AML.
    Bennett J, Ishikawa C, Agarwal P, Yeung J, Sampson A, Uible E, Vick E, Bolanos LC, Hueneman K, Wunderlich M, Kolt A, Choi K, Volk A, Greis KD, Rosenbaum J, Hoyt SB, Thomas CJ, Starczynowski DT., Free PMC Article

    09/15/2023
    MYD88 L265P mutation in neurologic autoimmunity without evidence of malignancy.

    MYD88 L265P mutation in neurologic autoimmunity without evidence of malignancy.
    Oetjen LK, Bhattacharyya S, Galetta K.

    09/11/2023
    [Association of gene polymorphisms of MyD88 and TICAM1 and their interactions with community-acquired pneumonia in children].

    [Association of gene polymorphisms of MyD88 and TICAM1 and their interactions with community-acquired pneumonia in children].
    Yang Y, Yang SY, Chen ZB, Liu L., Free PMC Article

    09/6/2023
    The oncogenic human B-cell lymphoma MYD88 L265P mutation genocopies activation by phosphorylation at the Toll/interleukin-1 receptor (TIR) domain.

    The oncogenic human B-cell lymphoma MYD88 L265P mutation genocopies activation by phosphorylation at the Toll/interleukin-1 receptor (TIR) domain.
    Minderman M, Lantermans H, van der Zwaan C, Hoogendijk AJ, van den Biggelaar M, Kersten MJ, Spaargaren M, Pals ST., Free PMC Article

    08/23/2023
    The Prevalence of MYD88 L265P and TNFAIP3 Mutations and Their Correlations with Clinico-Hematological Profile in Egyptian Patients with Diffuse Large B Cell Lymphoma.

    The Prevalence of MYD88 L265P and TNFAIP3 Mutations and Their Correlations with Clinico-Hematological Profile in Egyptian Patients with Diffuse Large B Cell Lymphoma.
    Elbaz O, Shaat RM, Abd El Ghaffar HA, Shamaa S, Abdel-Masseih HM, Anber N, Mortada MI., Free PMC Article

    08/2/2023
    SARS-CoV-2 ORF8 Mediates Signals in Macrophages and Monocytes through MyD88 Independently of the IL-17 Receptor.

    SARS-CoV-2 ORF8 Mediates Signals in Macrophages and Monocytes through MyD88 Independently of the IL-17 Receptor.
    Ponde NO, Shoger KE, Khatun MS, Sarkar MK, Dey I, Taylor TC, Cisney RN, Arunkumar SP, Gudjonsson JE, Kolls JK, Gottschalk RA, Gaffen SL.,

    07/19/2023
    Human gammadelta T cells induce CD8[+] T cell antitumor responses via antigen-presenting effect through HSP90-MyD88-mediated activation of JNK.

    Human γδ T cells induce CD8(+) T cell antitumor responses via antigen-presenting effect through HSP90-MyD88-mediated activation of JNK.
    Wang S, Li H, Chen T, Zhou H, Zhang W, Lin N, Yu X, Lou Y, Li B, Yinwang E, Wang Z, Wang K, Xue Y, Qu H, Lin P, Sun H, Teng W, Mou H, Chai X, Cai Z, Ye Z., Free PMC Article

    05/31/2023
    Prevalence and prognostic value of MYD88 and CD79B mutations in ocular adnexal large B-cell lymphoma: a reclassification of ocular adnexal large B-cell lymphoma.

    Prevalence and prognostic value of MYD88 and CD79B mutations in ocular adnexal large B-cell lymphoma: a reclassification of ocular adnexal large B-cell lymphoma.
    Kirkegaard MK, Minderman M, Sjö LD, Pals ST, Eriksen PRG, Heegaard S.

    03/28/2023
    Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia.

    Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia.
    García-García A, Pérez de Diego R, Flores C, Rinchai D, Solé-Violán J, Deyà-Martínez À, García-Solis B, Lorenzo-Salazar JM, Hernández-Brito E, Lanz AL, Moens L, Bucciol G, Almuqamam M, Domachowske JB, Colino E, Santos-Perez JL, Marco FM, Pignata C, Bousfiha A, Turvey SE, Bauer S, Haerynck F, Ocejo-Vinyals JG, Lendinez F, Prader S, Naumann-Bartsch N, Pachlopnik Schmid J, Biggs CM, Hildebrand K, Dreesman A, Cárdenes MÁ, Ailal F, Benhsaien I, Giardino G, Molina-Fuentes A, Fortuny C, Madhavarapu S, Conway DH, Prando C, Schidlowski L, Martínez de Saavedra Álvarez MT, Alfaro R, Rodríguez de Castro F, ESID Registry Working Party, COVID Human Genetic Effort, Meyts I, Hauck F, Puel A, Bastard P, Boisson B, Jouanguy E, Abel L, Cobat A, Zhang Q, Casanova JL, Alsina L, Rodríguez-Gallego C., Free PMC Article

    03/14/2023
    Genetic and Clinical Characteristics of Korean Chronic Lymphocytic Leukemia Patients with High Frequencies of MYD88 Mutations.

    Genetic and Clinical Characteristics of Korean Chronic Lymphocytic Leukemia Patients with High Frequencies of MYD88 Mutations.
    Ahn A, Kim HS, Kim TY, Lee JM, Kang D, Yu H, Lee CY, Kim Y, Eom KS, Kim M., Free PMC Article

    02/28/2023
    Aqueous Humor-Derived MYD88 L265P Mutation Analysis in Vitreoretinal Lymphoma: A Potential Less Invasive Method for Diagnosis and Treatment Response Assessment.

    Aqueous Humor-Derived MYD88 L265P Mutation Analysis in Vitreoretinal Lymphoma: A Potential Less Invasive Method for Diagnosis and Treatment Response Assessment.
    Demirci H, Rao RC, Elner VM, Demirci FY, Axenov L, Betz B, Behdad A, Brown N.

    02/11/2023
    Adaptor protein MyD88 confers the susceptibility to stress via amplifying immune danger signals.

    Adaptor protein MyD88 confers the susceptibility to stress via amplifying immune danger signals.
    Yao XP, Ye J, Feng T, Jiang FC, Zhou P, Wang F, Chen JG, Wu PF., Free PMC Article

    01/28/2023
    Prognostic impact of MYD88 and CXCR4 mutations assessed by droplet digital polymerase chain reaction in IgM monoclonal gammopathy of undetermined significance and smouldering Waldenstrom macroglobulinaemia.

    Prognostic impact of MYD88 and CXCR4 mutations assessed by droplet digital polymerase chain reaction in IgM monoclonal gammopathy of undetermined significance and smouldering Waldenström macroglobulinaemia.
    Moreno DF, López-Guerra M, Paz S, Oliver-Caldés A, Mena MP, Correa JG, Battram AM, Osuna M, Rivas-Delgado A, Rodríguez-Lobato LG, Cardús O, Tovar N, Cibeira MT, Jiménez-Segura R, Bladé J, Rosiñol L, Colomer D, Fernández de Larrea C., Free PMC Article

    01/21/2023
    Clinical significance of MYD88 non-L265P mutations in diffuse large B-cell lymphoma.

    Clinical significance of MYD88 non-L265P mutations in diffuse large B-cell lymphoma.
    Xie J, Shen X, Shi Q, Yi H, Ouyang B, Zhang Z, Gu Y, Dong L.

    12/24/2022
    Knockdown RBM15 Inhibits Colorectal Cancer Cell Proliferation and Metastasis Via N6-Methyladenosine (m6A) Modification of MyD88 mRNA.

    Knockdown RBM15 Inhibits Colorectal Cancer Cell Proliferation and Metastasis Via N6-Methyladenosine (m6A) Modification of MyD88 mRNA.
    Zhang Z, Mei Y, Hou M.

    12/24/2022
    PAUF Induces Migration of Human Pancreatic Cancer Cells Exclusively via the TLR4/MyD88/NF-kappaB Signaling Pathway.

    PAUF Induces Migration of Human Pancreatic Cancer Cells Exclusively via the TLR4/MyD88/NF-κB Signaling Pathway.
    Youn SE, Jiang F, Won HY, Hong DE, Kang TH, Park YY, Koh SS., Free PMC Article

    10/22/2022
    Necroptosis of nucleus pulposus cells involved in intervertebral disc degeneration through MyD88 signaling.

    Necroptosis of nucleus pulposus cells involved in intervertebral disc degeneration through MyD88 signaling.
    Fan H, Chen Z, Tang HB, Shan LQ, Chen ZY, Liu SC, Zhang YY, Guo XY, Yang H, Hao DJ., Free PMC Article

    10/15/2022
    Circular RNA MELK Promotes Chondrocyte Apoptosis and Inhibits Autophagy in Osteoarthritis by Regulating MYD88/NF-kappaB Signaling Axis through MicroRNA-497-5p.

    Circular RNA MELK Promotes Chondrocyte Apoptosis and Inhibits Autophagy in Osteoarthritis by Regulating MYD88/NF-κB Signaling Axis through MicroRNA-497-5p.
    Zhang Y, Lu R, Huang X, Yin E, Yang Y, Yi C, You H, Song X, Yuan X., Free PMC Article

    09/17/2022
    [Exploring the detection of MYD88 mutation in patients with Waldenstrom macroglobulinemia by different methods and specimens].

    [Exploring the detection of MYD88 mutation in patients with Waldenström macroglobulinemia by different methods and specimens].
    Tao Y, Pan ZK, Wang S, Wang L, Zhao WL., Free PMC Article

    06/18/2022
    A new role for the SRC family kinase HCK as a driver of SYK activation in MYD88 mutated lymphomas.

    A new role for the SRC family kinase HCK as a driver of SYK activation in MYD88 mutated lymphomas.
    Munshi M, Liu X, Kofides A, Tsakmaklis N, Guerrera ML, Hunter ZR, Palomba ML, Argyropoulos KV, Patterson CJ, Canning AG, Meid K, Gustine J, Branagan AR, Flynn CA, Sarosiek S, Castillo JJ, Wang J, Buhrlage SJ, Gray NS, Munshi NC, Anderson KC, Treon SP, Yang G., Free PMC Article

    06/18/2022
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