Nuclear autoantigenic sperm protein facilitates glioblastoma progression and radioresistance by regulating the ANXA2/STAT3 axis. | Nuclear autoantigenic sperm protein facilitates glioblastoma progression and radioresistance by regulating the ANXA2/STAT3 axis. Qiu Y, Pei D, Wang M, Wang Q, Duan W, Wang L, Liu K, Guo Y, Luo L, Guo Z, Guan F, Wang Z, Xing A, Liu Z, Ma Z, Jiang G, Yan D, Liu X, Zhang Z, Wang W., Free PMC Article | 04/29/2024 |
sNASP Mutation Aggravates to the TLR4-Mediated Inflammation in SLE by TAK1 Pathway. | sNASP Mutation Aggravates to the TLR4-Mediated Inflammation in SLE by TAK1 Pathway. Bao Y, Lian M, Chen Y, Gu X, Cao K, Du X, Ju J., Free PMC Article | 10/2/2023 |
[Hepatic fibrosis aggravation in nuclear autoantigenic sperm protein (NASP) mutant mice induced by concanavalin A]. | [Hepatic fibrosis aggravation in nuclear autoantigenic sperm protein (NASP) mutant mice induced by concanavalin A]. Zhang Y, Yan H, Zhu J, Chen L, Wang H, Ju J. | 07/16/2022 |
A Variant of sNASP Exacerbates Lymphocyte Subset Disorder and Nephritis in a Spontaneous Lupus Model Sle1.Yaa Mouse. | A Variant of sNASP Exacerbates Lymphocyte Subset Disorder and Nephritis in a Spontaneous Lupus Model Sle1.Yaa Mouse. Zhang J, Du X, Wang H, Bao Y, Lian M, Xu Z, Ju J., Free PMC Article | 03/5/2022 |
A Variant of the Histone-Binding Protein sNASP Contributes to Mouse Lupus. | A Variant of the Histone-Binding Protein sNASP Contributes to Mouse Lupus. Ju J, Xu J, Zhu Y, Fu X, Morel L, Xu Z., Free PMC Article | 06/13/2020 |
an increase of miR-29a, and hence decrease of Nasp, may contribute to inhibit cell proliferation during postnatal organ development. | MicroRNA-29a inhibited epididymal epithelial cell proliferation by targeting nuclear autoantigenic sperm protein (NASP). Ma W, Xie S, Ni M, Huang X, Hu S, Liu Q, Liu A, Zhang J, Zhang Y., Free PMC Article | 05/19/2012 |
NASP controls the ability of HSPA2 to activate CDC2 for CDC2/cyclin B1 complex formation; therefore, tNASP's role is to provide the functional link between linker histones and cell cycle progression during meiosis. | Linker histones stimulate HSPA2 ATPase activity through NASP binding and inhibit CDC2/Cyclin B1 complex formation during meiosis in the mouse. Alekseev OM, Richardson RT, O'Rand MG., Free PMC Article | 01/21/2010 |
in the cytoplasm linker histones are bound to a complex containing NASP and HSP90 whose ATPase activity is stimulated by binding NASP | Association of NASP with HSP90 in mouse spermatogenic cells: stimulation of ATPase activity and transport of linker histones into nuclei. Alekseev OM, Widgren EE, Richardson RT, O'Rand MG. | 01/21/2010 |
NASP and the linker histones are key players in the assembly of chromatin after DNA replication | Nuclear autoantigenic sperm protein (NASP), a linker histone chaperone that is required for cell proliferation. Richardson RT, Alekseev OM, Grossman G, Widgren EE, Thresher R, Wagner EJ, Sullivan KD, Marzluff WF, O'Rand MG. | 01/21/2010 |
overexpression affects progression through cell cycle | Overexpression of the Linker histone-binding protein tNASP affects progression through the cell cycle. Alekseev OM, Bencic DC, Richardson RT, Widgren EE, O'Rand MG. | 01/21/2010 |
Sp1 and Ets are the primary activators of the NASP promoter. | Characterization of the NASP promoter in 3T3 fibroblasts and mouse spermatogenic cells. Richardson RT, Alekseev O, Alekseev OM, O'Rand MG. | 01/21/2010 |