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    GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 [ Homo sapiens (human) ]

    Gene ID: 51809, updated on 3-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The expression of O-linked glycosyltransferase GALNT7 in breast cancer is dependent on estrogen-, progesterone-, and HER2-receptor status, with prognostic implications.

    The expression of O-linked glycosyltransferase GALNT7 in breast cancer is dependent on estrogen-, progesterone-, and HER2-receptor status, with prognostic implications.
    Berkel C, Cacan E.

    01/17/2024
    SPDEF enhances cancer stem cell-like properties and tumorigenesis through directly promoting GALNT7 transcription in luminal breast cancer.

    SPDEF enhances cancer stem cell-like properties and tumorigenesis through directly promoting GALNT7 transcription in luminal breast cancer.
    Li J, Wan X, Xie D, Yuan H, Pei Q, Luo Y, Chen Y, Xian J, Ye T., Free PMC Article

    08/30/2023
    Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth.

    Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth.
    Scott E, Hodgson K, Calle B, Turner H, Cheung K, Bermudez A, Marques FJG, Pye H, Yo EC, Islam K, Oo HZ, McClurg UL, Wilson L, Thomas H, Frame FM, Orozco-Moreno M, Bastian K, Arredondo HM, Roustan C, Gray MA, Kelly L, Tolson A, Mellor E, Hysenaj G, Goode EA, Garnham R, Duxfield A, Heavey S, Stopka-Farooqui U, Haider A, Freeman A, Singh S, Johnston EW, Punwani S, Knight B, McCullagh P, McGrath J, Crundwell M, Harries L, Bogdan D, Westaby D, Fowler G, Flohr P, Yuan W, Sharp A, de Bono J, Maitland NJ, Wisnovsky S, Bertozzi CR, Heer R, Guerrero RH, Daugaard M, Leivo J, Whitaker H, Pitteri S, Wang N, Elliott DJ, Schumann B, Munkley J., Free PMC Article

    03/21/2023
    MiR-30c facilitates natural killer cell cytotoxicity to lung cancer through targeting GALNT7.

    MiR-30c facilitates natural killer cell cytotoxicity to lung cancer through targeting GALNT7.
    Gao F, Han J, Jia L, He J, Wang Y, Chen M, Liu X, He X.

    02/11/2023
    Long non-coding RNA TP73-AS1 contributes to glioma tumorigenesis by sponging the miR-103a/GALNT7 pathway.

    Long non-coding RNA TP73-AS1 contributes to glioma tumorigenesis by sponging the miR-103a/GALNT7 pathway.
    Wang JB, Chen XL, Han ZB, Wang HW, Wang ZH, Li NN, Lin ZG.

    09/4/2021
    Results indicated that SNHG7 facilitated the proliferation and metastasis as a competing endogenous RNA to regulate GALNT7 expression by sponging miR-34a in CRC cell lines.

    Long non-coding RNA-SNHG7 acts as a target of miR-34a to increase GALNT7 level and regulate PI3K/Akt/mTOR pathway in colorectal cancer progression.
    Li Y, Zeng C, Hu J, Pan Y, Shan Y, Liu B, Jia L., Free PMC Article

    11/23/2019
    crystallographic analysis of GalNAc-T7, a GalNAc-T capable of glycosylating consecutive sites, and of its complex with the donor substrate UDP-GalNAc

    Structural basis of carbohydrate transfer activity of UDP-GalNAc: Polypeptide N-acetylgalactosaminyltransferase 7.
    Yu C, Liang L, Yin Y.

    11/16/2019
    miR-494 and GALNT7 play oncogenic roles in nasopharyngeal carcinoma.

    GALNT7, a target of miR-494, participates in the oncogenesis of nasopharyngeal carcinoma.
    Nie GH, Luo L, Duan HF, Li XQ, Yin MJ, Li Z, Zhang W.

    02/18/2017
    High expression of GALNT7 promotes migration and invasion and lymph node metastasis in esophageal squamous cell carcinoma.

    miR-214 inhibits invasion and migration via downregulating GALNT7 in esophageal squamous cell cancer.
    Lu Q, Xu L, Li C, Yuan Y, Huang S, Chen H.

    02/18/2017
    GALNT7 and CDK16 were confirmed to be the direct targets of miR-494. These results suggested that miR-494 play an inhibitory role in the tumorigenesis of NPC

    Functional elucidation of miR-494 in the tumorigenesis of nasopharyngeal carcinoma.
    Duan HF, Li XQ, Hu HY, Li YC, Cai Z, Mei XS, Yu P, Nie LP, Zhang W, Yu ZD, Nie GH., Free PMC Article

    03/5/2016
    The study of miR-34a, miR-34c and its novel target, GALNT7, may serve as novel potential makers for laryngeal squamous cell carcinoma therapy.

    MicroRNA‑34a/c function as tumor suppressors in Hep‑2 laryngeal carcinoma cells and may reduce GALNT7 expression.
    Li W, Ma H, Sun J.

    10/25/2014
    miR-214 is a new regulator of GALNT7, and both miR-214 and GALNT7 play important roles in the pathogenesis of cervical cancer

    MicroRNA-214 suppresses growth and invasiveness of cervical cancer cells by targeting UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7.
    Peng RQ, Wan HY, Li HF, Liu M, Li X, Tang H., Free PMC Article

    07/21/2012
    Ectopic expression of miR-30b/30d promoted the metastatic behavior of melanoma cells by directly targeting the GalNAc transferase GALNT7.

    miR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis.
    Gaziel-Sovran A, Segura MF, Di Micco R, Collins MK, Hanniford D, Vega-Saenz de Miera E, Rakus JF, Dankert JF, Shang S, Kerbel RS, Bhardwaj N, Shao Y, Darvishian F, Zavadil J, Erlebacher A, Mahal LK, Osman I, Hernando E., Free PMC Article

    09/10/2011
    MicroRNA miR-378 regulates nephronectin expression modulating osteoblast differentiation by targeting GalNT-7

    MicroRNA miR-378 regulates nephronectin expression modulating osteoblast differentiation by targeting GalNT-7.
    Kahai S, Lee SC, Lee DY, Yang J, Li M, Wang CH, Jiang Z, Zhang Y, Peng C, Yang BB., Free PMC Article

    03/15/2010
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