| miR-449a ameliorates acute rejection after liver transplantation via targeting procollagen-lysine1,2-oxoglutarate5-dioxygenase 1 in macrophages. | miR-449a ameliorates acute rejection after liver transplantation via targeting procollagen-lysine1,2-oxoglutarate5-dioxygenase 1 in macrophages.
Cao ZR, Zheng WX, Jiang YX, Chai H, Gong JH, Zhao MJ, Yan P, Liu YY, Liu XY, Huang ZT, Yang H, Peng DD, Zong KZ, Wu ZJ. | 03/15/2023 |
| P3H4 and PLOD1 expression associates with poor prognosis in bladder cancer. | P3H4 and PLOD1 expression associates with poor prognosis in bladder cancer.
Zhang J, Dong Y, Shi Z, He H, Chen J, Zhang S, Wu W, Zhang Q, Han C, Hao L. | 07/23/2022 |
| PLOD1 acts as a tumor promoter in glioma via activation of the HSF1 signaling pathway. | PLOD1 acts as a tumor promoter in glioma via activation of the HSF1 signaling pathway.
Yuan B, Xu Y, Zheng S. | 03/26/2022 |
| PLOD1 promotes cell growth and aerobic glycolysis by regulating the SOX9/PI3K/Akt/mTOR signaling pathway in gastric cancer. | PLOD1 promotes cell growth and aerobic glycolysis by regulating the SOX9/PI3K/Akt/mTOR signaling pathway in gastric cancer.
Zhang Y, Wu Y, Su X. | 01/22/2022 |
| Characterization of a cancer-associated Epstein-Barr virus EBNA1 variant reveals a novel interaction with PLOD1 and PLOD3. | Characterization of a cancer-associated Epstein-Barr virus EBNA1 variant reveals a novel interaction with PLOD1 and PLOD3.
Shire K, Marcon E, Greenblatt J, Frappier L. | 01/8/2022 |
| New mechanistic insights to PLOD1-mediated human vascular disease. | New mechanistic insights to PLOD1-mediated human vascular disease.
Koenig SN, Cavus O, Williams J, Bernier M, Tonniges J, Sucharski H, Dew T, Akel M, Baker P, Madiai F, De Giorgi F, Scietti L, Faravelli S, Forneris F, Mohler PJ, Bradley EA., Free PMC Article | 01/8/2022 |
| A floppy infant without lingual frenulum and kyphoscoliosis: Ehlers Danlos syndrome case report. | A floppy infant without lingual frenulum and kyphoscoliosis: Ehlers Danlos syndrome case report.
Conti R, Zanchi C, Barbi E., Free PMC Article | 11/6/2021 |
| PLODs are overexpressed in ovarian cancer and are associated with gap junctions via connexin 43. | PLODs are overexpressed in ovarian cancer and are associated with gap junctions via connexin 43.
Guo T, Gu C, Li B, Xu C. | 08/7/2021 |
| Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-kappaB signaling. | Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling.
Wang Z, Shi Y, Ying C, Jiang Y, Hu J., Free PMC Article | 07/31/2021 |
| PLOD1 Is a Prognostic Biomarker and Mediator of Proliferation and Invasion in Osteosarcoma. | PLOD1 Is a Prognostic Biomarker and Mediator of Proliferation and Invasion in Osteosarcoma.
Jiang H, Guo W, Yuan S, Song L., Free PMC Article | 05/8/2021 |
| PLOD1, a target of miR-34c, contributes to cell growth and metastasis via repressing LATS1 phosphorylation and inactivating Hippo pathway in osteosarcoma. | PLOD1, a target of miR-34c, contributes to cell growth and metastasis via repressing LATS1 phosphorylation and inactivating Hippo pathway in osteosarcoma.
Wu X, Xiang H, Cong W, Yang H, Zhang G, Wang Y, Guo Z, Shen Y, Chen B. | 01/9/2021 |
| Procollagen-lysine, 2-oxoglutarate 5-dioxygenases 1, 2, and 3 are potential prognostic indicators in patients with clear cell renal cell carcinoma. | Procollagen-lysine, 2-oxoglutarate 5-dioxygenases 1, 2, and 3 are potential prognostic indicators in patients with clear cell renal cell carcinoma.
Xu WH, Xu Y, Wang J, Tian X, Wu J, Wan FN, Wang HK, Qu YY, Zhang HL, Ye DW., Free PMC Article | 09/5/2020 |
| the present study showed that PLOD1 may be a potential prognostic marker and therapeutic target for Bladder cancer. | Aberrantly expressed PLOD1 promotes cancer aggressiveness in bladder cancer: a potential prognostic marker and therapeutic target.
Yamada Y, Kato M, Arai T, Sanada H, Uchida A, Misono S, Sakamoto S, Komiya A, Ichikawa T, Seki N., Free PMC Article | 05/2/2020 |
| results indicated that PLOD1 is highly expressed in gastrointestinal carcinoma and is a potential prognostic marker and therapeutic target | High Expression of PLOD1 Drives Tumorigenesis and Affects Clinical Outcome in Gastrointestinal Carcinoma.
Wang D, Zhang S, Chen F. | 10/13/2018 |
| Ehlers Danlos syndrome in two children was confirmed by mutations in PLOD1 gene. Initially patients were thought to have either a diagnosis of classical EDS (cEDS) or a neuromuscular disorder due to absence of (congenital) scoliosis. | Ehlers Danlos syndrome, kyphoscoliotic type due to Lysyl Hydroxylase 1 deficiency in two children without congenital or early onset kyphoscoliosis.
van Dijk FS, Mancini GMS, Maugeri A, Cobben JM. | 12/9/2017 |
| Deficiency of the enzyme lysyl hydroxylase 1 (LH1) due to mutations in PLOD1 results in underhydroxylation of collagen lysyl residues and, hence, in the abnormal formation of collagen cross-links. | Kyphoscoliotic type of Ehlers-Danlos Syndrome (EDS VIA) in six Egyptian patients presenting with a homogeneous clinical phenotype.
Abdalla EM, Rohrbach M, Bürer C, Kraenzlin M, El-Tayeby H, Elbelbesy MF, Nabil A, Giunta C. | 10/10/2015 |
| Compared to slow progressing Alzheimer's disease, PLOD1 is upregulated in fast progressing Alzheimer's disease ;patients. | Gene expression profiling of peripheral blood leukocytes shows consistent longitudinal downregulation of TOMM40 and upregulation of KIR2DL5A, PLOD1, and SLC2A8 among fast progressors in early Alzheimer's disease.
Chong MS, Goh LK, Lim WS, Chan M, Tay L, Chen G, Feng L, Ng TP, Tan CH, Lee TS. | 11/2/2013 |
| Data show that homozygous and compound heterozygous changes found in PLOD1 and SLC2A10 may confer autosomal recessive effects, and three MYH11, ACTA2 and COL3A1 heterozygous variants were considered as putative pathogenic gene alterations. | Rapid detection of gene mutations responsible for non-syndromic aortic aneurysm and dissection using two different methods: resequencing microarray technology and next-generation sequencing.
Sakai H, Suzuki S, Mizuguchi T, Imoto K, Yamashita Y, Doi H, Kikuchi M, Tsurusaki Y, Saitsu H, Miyake N, Masuda M, Matsumoto N. | 05/19/2012 |
| Common polymorphisms in four candidate genes (COL11A1, COL18A1, FBN1 and PLOD1) were unlikely to play important roles in the genetic susceptibility to high myopia. | A DNA pooling-based case-control study of myopia candidate genes COL11A1, COL18A1, FBN1, and PLOD1 in a Chinese population.
Yip SP, Leung KH, Fung WY, Ng PW, Sham PC, Yap MK., Free PMC Article | 09/10/2011 |
| Meta-analysis of gene-disease association. (HuGE Navigator) | Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".
Johnatty SE, Beesley J, Chen X, Macgregor S, Duffy DL, Spurdle AB, deFazio A, Gava N, Webb PM, Rossing MA, Doherty JA, Goodman MT, Lurie G, Thompson PJ, Wilkens LR, Ness RB, Moysich KB, Chang-Claude J, Wang-Gohrke S, Cramer DW, Terry KL, Hankinson SE, Tworoger SS, Garcia-Closas M, Yang H, Lissowska J, Chanock SJ, Pharoah PD, Song H, Whitemore AS, Pearce CL, Stram DO, Wu AH, Pike MC, Gayther SA, Ramus SJ, Menon U, Gentry-Maharaj A, Anton-Culver H, Ziogas A, Hogdall E, Kjaer SK, Hogdall C, Berchuck A, Schildkraut JM, Iversen ES, Moorman PG, Phelan CM, Sellers TA, Cunningham JM, Vierkant RA, Rider DN, Goode EL, Haviv I, Chenevix-Trench G, Ovarian Cancer Association Consortium, Australian Ovarian Cancer Study Group, Australian Cancer Study (Ovarian Cancer)., Free PMC Article | 09/15/2010 |
| The results suggest that PLOD1 at 1p36, individually or in different combinations, contribute to osteoporosis susceptibility in Chinese. | Multiple osteoporosis susceptibility genes on chromosome 1p36 in Chinese.
Huang QY, Li GH, Kung AW. | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesAssociation of candidate gene polymorphisms with bone mineral density in community-dwelling Japanese women and men.
Yamada Y, Ando F, Shimokata H. Association of PLOD1 polymorphisms with bone mineral density in a population-based study of women from the UK.
Tasker PN, Macdonald H, Fraser WD, Reid DM, Ralston SH, Albagha OM. Association analysis of bone mineral density and single nucleotide polymorphisms in two candidate genes on chromosome 1p36.
Spotila LD, Rodriguez H, Koch M, Tenenhouse HS, Tenenhouse A, Li H, Devoto M. | 03/13/2008 |
| Characterization of three fragments that constitute the monomers of the human lysyl hydroxylase isoenzymes 1-3. The 30-kDa N-terminal fragment is not required for lysyl hydroxylase activity | Characterization of three fragments that constitute the monomers of the human lysyl hydroxylase isoenzymes 1-3. The 30-kDa N-terminal fragment is not required for lysyl hydroxylase activity.
Rautavuoma K, Takaluoma K, Passoja K, Pirskanen A, Kvist AP, Kivirikko KI, Myllyharju J. | 01/21/2010 |
| Results indicate that a C-terminal 40 amino acid segment of lysyl hydroxylase confers endoplasmic reticulum residency in a KDEL-receptor-independent manner. | Retrieval-independent localization of lysyl hydroxylase in the endoplasmic reticulum via a peptide fold in its iron-binding domain.
Suokas M, Lampela O, Juffer AH, Myllylä R, Kellokumpu S., Free PMC Article | 01/21/2010 |