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    Tug1 taurine upregulated gene 1 [ Mus musculus (house mouse) ]

    Gene ID: 544752, updated on 7-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Aerobic exercise suppresses cognitive injury in patients with Alzheimer's disease by regulating long non-coding RNA TUG1.

    Aerobic exercise suppresses cognitive injury in patients with Alzheimer's disease by regulating long non-coding RNA TUG1.
    Chen J, Su C, Ma Z, Ou X, Zhan M, Hu J.

    04/3/2024
    Involvement of NRON and TUG1 long noncoding RNAs in inflammation and the pathogenesis of EAE.

    Involvement of NRON and TUG1 long noncoding RNAs in inflammation and the pathogenesis of EAE.
    Kioumarsi E, Kohan L, Noorbakhsh F, Shirian S, Gorji A, Zare-Chahoki A.

    12/22/2023
    LncRNA Tug1 relieves the steatosis of SelenoF-knockout hepatocytes via sponging miR-1934-3p.

    LncRNA Tug1 relieves the steatosis of SelenoF-knockout hepatocytes via sponging miR-1934-3p.
    Wang W, Miao Z, Qi X, Wang B, Liu Q, Shi X, Xu S.

    12/5/2023
    Long noncoding RNA TUG1 regulates smooth muscle cell differentiation via KLF4-myocardin axis.

    Long noncoding RNA TUG1 regulates smooth muscle cell differentiation via KLF4-myocardin axis.
    Bharadhwaj RA, Kumarswamy R.,

    10/11/2023
    TUG1 protects against ferroptosis of hepatic stellate cells by upregulating PDK4-mediated glycolysis.

    TUG1 protects against ferroptosis of hepatic stellate cells by upregulating PDK4-mediated glycolysis.
    Zhang X, Zhao L, Ying K, Xu J, Huang Y, Zhu R, Ding Y, Cai W, Wu X, Miao D, Xu Q, Zeng Y, Yu F.

    09/18/2023
    Bone marrow mesenchymal stem cells derived exosomal Lnc TUG1 promotes bone fracture recovery via miR-22-5p/Anxa8 axis.

    Bone marrow mesenchymal stem cells derived exosomal Lnc TUG1 promotes bone fracture recovery via miR-22-5p/Anxa8 axis.
    Li W, Li L, Cui R, Chen X, Hu H, Qiu Y., Free PMC Article

    04/19/2023
    Long Non-Coding RNA TUG1 Attenuates Insulin Resistance in Mice with Gestational Diabetes Mellitus via Regulation of the MicroRNA-328-3p/SREBP-2/ERK Axis.

    Long Non-Coding RNA TUG1 Attenuates Insulin Resistance in Mice with Gestational Diabetes Mellitus via Regulation of the MicroRNA-328-3p/SREBP-2/ERK Axis.
    Tang X, Qin Q, Xu W, Zhang X., Free PMC Article

    03/24/2023
    N6-Methyladenosine Methyltransferase METTL3 Alleviates Diabetes-Induced Testicular Damage through Modulating TUG1/Clusterin Axis.

    N6-Methyladenosine Methyltransferase METTL3 Alleviates Diabetes-Induced Testicular Damage through Modulating TUG1/Clusterin Axis.
    Tian Y, Xiao YH, Sun C, Liu B, Sun F., Free PMC Article

    03/24/2023
    LncRNA TUG1 Exacerbates Myocardial Fibrosis in Diabetic Cardiomyopathy by Modulating the microRNA-145a-5p/Cfl2 Axis.

    LncRNA TUG1 Exacerbates Myocardial Fibrosis in Diabetic Cardiomyopathy by Modulating the microRNA-145a-5p/Cfl2 Axis.
    Wang K, Lin Y, Shen H, Yu S, Xu J.

    03/11/2023
    Silencing of Long Noncoding RNA TUG1 Ameliorates Atherosclerosis-Induced Myocardial Injury by Upregulating microRNA-30b-3p and Downregulating Brd4.

    Silencing of Long Noncoding RNA TUG1 Ameliorates Atherosclerosis-Induced Myocardial Injury by Upregulating microRNA-30b-3p and Downregulating Brd4.
    Li DL, Zheng BB, Zeng X, Li J, Dai RZ.

    01/28/2023
    Photobiomodulation promotes spinal cord injury repair by inhibiting macrophage polarization through lncRNA TUG1-miR-1192/TLR3 axis.

    Photobiomodulation promotes spinal cord injury repair by inhibiting macrophage polarization through lncRNA TUG1-miR-1192/TLR3 axis.
    Ju C, Ma Y, Zuo X, Wang X, Song Z, Zhang Z, Zhu Z, Li X, Liang Z, Ding T, Hu X, Wang Z., Free PMC Article

    01/28/2023
    LncRNA Tug1 Contributes Post-stroke NLRP3 Inflammasome-Dependent Pyroptosis via miR-145a-5p/Tlr4 Axis.

    LncRNA Tug1 Contributes Post-stroke NLRP3 Inflammasome-Dependent Pyroptosis via miR-145a-5p/Tlr4 Axis.
    Yao M, Luo Y, Li H, Liao S, Yu J.

    10/15/2022
    Long non-coding RNA Tug1 modulates mitochondrial and myogenic responses to exercise in skeletal muscle.

    Long non-coding RNA Tug1 modulates mitochondrial and myogenic responses to exercise in skeletal muscle.
    Trewin AJ, Silver J, Dillon HT, Della Gatta PA, Parker L, Hiam DS, Lee YP, Richardson M, Wadley GD, Lamon S., Free PMC Article

    07/30/2022
    LncRNA TUG1 ameliorates diabetic nephropathy via inhibition of PU.1/RTN1 signaling pathway.

    LncRNA TUG1 ameliorates diabetic nephropathy via inhibition of PU.1/RTN1 signaling pathway.
    Meng D, Wu L, Li Z, Ma X, Zhao S, Zhao D, Qin G.

    05/21/2022
    Role of lncRNA TUG1 in Adenomyosis and its Regulatory Mechanism in Endometrial Epithelial Cell Functions.

    Role of lncRNA TUG1 in Adenomyosis and its Regulatory Mechanism in Endometrial Epithelial Cell Functions.
    Yuan B, Wang W, Zhao H, Wang L.

    04/23/2022
    Interfering TUG1 Attenuates Cerebrovascular Endothelial Apoptosis and Inflammatory injury After Cerebral Ischemia/Reperfusion via TUG1/miR-410/FOXO3 ceRNA Axis.

    Interfering TUG1 Attenuates Cerebrovascular Endothelial Apoptosis and Inflammatory injury After Cerebral Ischemia/Reperfusion via TUG1/miR-410/FOXO3 ceRNA Axis.
    He Z, Zhao Y, Zhu Y, Wang W, Liu X, Lu F.

    04/16/2022
    LncRNA TUG1 attenuates ischaemia-reperfusion-induced apoptosis of renal tubular epithelial cells by sponging miR-144-3p via targeting Nrf2.

    LncRNA TUG1 attenuates ischaemia-reperfusion-induced apoptosis of renal tubular epithelial cells by sponging miR-144-3p via targeting Nrf2.
    Zhao S, Chen W, Li W, Yu W, Li S, Rao T, Ruan Y, Zhou X, Liu C, Qi Y, Cheng F., Free PMC Article

    02/26/2022
    The Long-Noncoding RNA TUG1 Regulates Oxygen-Induced Retinal Neovascularization in Mice via MiR-299.

    The Long-Noncoding RNA TUG1 Regulates Oxygen-Induced Retinal Neovascularization in Mice via MiR-299.
    Wang Y, Wang X, Wang YX, Ma Y, Di Y., Free PMC Article

    02/19/2022
    Knockdown of lncRNA TUG1 attenuates cerebral ischemia/reperfusion injury through regulating miR-142-3p.

    Knockdown of lncRNA TUG1 attenuates cerebral ischemia/reperfusion injury through regulating miR-142-3p.
    Li L, Zhang Q, Wang Y, Yin S, Chi S, Han F, Wang W.

    02/19/2022
    PGC1alpha is required for the renoprotective effect of lncRNA Tug1 in vivo and links Tug1 with urea cycle metabolites.

    PGC1α is required for the renoprotective effect of lncRNA Tug1 in vivo and links Tug1 with urea cycle metabolites.
    Li L, Long J, Mise K, Galvan DL, Overbeek PA, Tan L, Kumar SV, Chan WK, Lorenzi PL, Chang BH, Danesh FR., Free PMC Article

    02/12/2022
    Functional delivery of lncRNA TUG1 by endothelial progenitor cells derived extracellular vesicles confers anti-inflammatory macrophage polarization in sepsis via impairing miR-9-5p-targeted SIRT1 inhibition.

    Functional delivery of lncRNA TUG1 by endothelial progenitor cells derived extracellular vesicles confers anti-inflammatory macrophage polarization in sepsis via impairing miR-9-5p-targeted SIRT1 inhibition.
    Ma W, Zhang W, Cui B, Gao J, Liu Q, Yao M, Ning H, Xing L., Free PMC Article

    02/5/2022
    SP1-induced lncRNA TUG1 regulates proliferation and apoptosis in islet cells of type 2 diabetes mellitus via the miR-188-3p/FGF5 axis.

    SP1-induced lncRNA TUG1 regulates proliferation and apoptosis in islet cells of type 2 diabetes mellitus via the miR-188-3p/FGF5 axis.
    Zhang P, Li YN, Tu S, Cheng XB.

    01/8/2022
    LncRNA TUG1 silencing enhances proliferation and migration of ox-LDL-treated human umbilical vein endothelial cells and promotes atherosclerotic vascular injury repairing via the Runx2/ANPEP axis.

    LncRNA TUG1 silencing enhances proliferation and migration of ox-LDL-treated human umbilical vein endothelial cells and promotes atherosclerotic vascular injury repairing via the Runx2/ANPEP axis.
    Du H, Yang L, Zhang H, Zhang X, Shao H.

    09/18/2021
    LncRNA TUG1 alleviates cardiac hypertrophy by targeting miR-34a/DKK1/Wnt-beta-catenin signalling.

    LncRNA TUG1 alleviates cardiac hypertrophy by targeting miR-34a/DKK1/Wnt-β-catenin signalling.
    Fang Q, Liu T, Yu C, Yang X, Shao Y, Shi J, Ye X, Zheng X, Yan J, Xu D, Zou X., Free PMC Article

    09/11/2021
    The protection of NF-kappaB inhibition on kidney injury of systemic lupus erythematosus mice may be correlated with lncRNA TUG1.

    The protection of NF-κB inhibition on kidney injury of systemic lupus erythematosus mice may be correlated with lncRNA TUG1.
    Cao HY, Li D, Wang YP, Lu HX, Sun J, Li HB.

    07/31/2021
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