Prox1 Suppresses Proliferation and Drug Resistance of Retinoblastoma Cells via Targeting Notch1. | Prox1 Suppresses Proliferation and Drug Resistance of Retinoblastoma Cells via Targeting Notch1. Zhang HL, Li N, Dong L, Ma HX, Yang MC. | 02/27/2024 |
PROX1 interaction with alpha-SMA-rich cancer-associated fibroblasts facilitates colorectal cancer progression and correlates with poor clinical outcomes and therapeutic resistance. | PROX1 interaction with α-SMA-rich cancer-associated fibroblasts facilitates colorectal cancer progression and correlates with poor clinical outcomes and therapeutic resistance. Lai SW, Cheng YC, Kiu KT, Yen MH, Chen YW, Yadav VK, Yeh CT, Kuo KT, Chang TC., Free PMC Article | 02/6/2024 |
Homeobox Protein PROX1 Expression is Negatively Regulated by Histone Deacetylase 1 and c-JUN Complex in MDA-MB-231 Human Breast Cancer Cells. | Homeobox Protein PROX1 Expression is Negatively Regulated by Histone Deacetylase 1 and c-JUN Complex in MDA-MB-231 Human Breast Cancer Cells. Jeong M, Jung E, Oh S, Shin SY. | 01/17/2024 |
PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway. | PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway. Ohata H, Shiokawa D, Sakai H, Kanda Y, Okimoto Y, Kaneko S, Hamamoto R, Nakagama H, Okamoto K. | 10/11/2023 |
Prox1 Suppresses the Proliferation of Breast Cancer Cells via Direct Inhibition of c-Myc Gene Expression. | Prox1 Suppresses the Proliferation of Breast Cancer Cells via Direct Inhibition of c-Myc Gene Expression. Michail A, Gkikas D, Stellas D, Kaltezioti V, Politis PK., Free PMC Article | 08/2/2023 |
Defects in vein valve PROX1/FOXC2 antithrombotic pathway in endothelial cells drive the hypercoagulable state induced by trauma and critical illness. | Defects in vein valve PROX1/FOXC2 antithrombotic pathway in endothelial cells drive the hypercoagulable state induced by trauma and critical illness. Hoofnagle MH, Hess A, Nalugo M, Ghosh S, Hughes SW, Fuchs A, Welsh JD, Kahn ML, Bochicchio GV, Randolph GJ, Leonard JM, Turnbull IR., | 07/28/2023 |
PROX1 restrains ferroptosis via SCD transcription activation in colorectal cancer. | PROX1 restrains ferroptosis via SCD transcription activation in colorectal cancer. Zhang R, Luo D, Shan Z, Yang Y, Qin Y, Li Q, Li X., Free PMC Article | 05/17/2023 |
Exosomal circ_0026611 contributes to lymphangiogenesis by reducing PROX1 acetylation and ubiquitination in human lymphatic endothelial cells (HLECs). | Exosomal circ_0026611 contributes to lymphangiogenesis by reducing PROX1 acetylation and ubiquitination in human lymphatic endothelial cells (HLECs). Yao W, Jia X, Zhu L, Xu L, Zhang Q, Xia T, Wei L., Free PMC Article | 02/23/2023 |
AMPK induces degradation of the transcriptional repressor PROX1 impairing branched amino acid metabolism and tumourigenesis. | AMPK induces degradation of the transcriptional repressor PROX1 impairing branched amino acid metabolism and tumourigenesis. Wang Y, Luo M, Wang F, Tong Y, Li L, Shu Y, Qiao K, Zhang L, Yan G, Liu J, Ji H, Xie Y, Zhang Y, Gao WQ, Liu Y., Free PMC Article | 12/10/2022 |
Circ_0007534 Silencing Inhibits the Proliferation, Migration and Invasion and Induces the Apoptosis of Glioma Cells Partly Through Down-Regulating PROX1 Via Elevating miR-22-3p Level. | Circ_0007534 Silencing Inhibits the Proliferation, Migration and Invasion and Induces the Apoptosis of Glioma Cells Partly Through Down-Regulating PROX1 Via Elevating miR-22-3p Level. Zheng Y, Wang Y, Mai R, Liu L, Zhu Z, Cao Y. | 10/22/2022 |
CircRFX3 Up-regulates Its Host Gene RFX3 to Facilitate Tumorigenesis and Progression of Glioma. | CircRFX3 Up-regulates Its Host Gene RFX3 to Facilitate Tumorigenesis and Progression of Glioma. Qian Y, Cheng B, Luo J, Hu Y, Gao L, Cheng H. | 06/25/2022 |
Prognostic Impact of LGR5, Prox1, and Notch1 Biomarkers in Stage II to III Colon Cancer. | Prognostic Impact of LGR5, Prox1, and Notch1 Biomarkers in Stage II to III Colon Cancer. Abdelrahman AE, El-Azony A, Elsebai E, Ibrahim HM. | 05/7/2022 |
PROX1 promotes breast cancer invasion and metastasis through WNT/beta-catenin pathway via interacting with hnRNPK. | PROX1 promotes breast cancer invasion and metastasis through WNT/β-catenin pathway via interacting with hnRNPK. Zhu L, Tian Q, Gao H, Wu K, Wang B, Ge G, Jiang S, Wang K, Zhou C, He J, Liu P, Ren Y, Wang B., Free PMC Article | 04/30/2022 |
PROX1, a Key Mediator of the Anti-Proliferative Effect of Rapamycin on Hepatocellular Carcinoma Cells. | PROX1, a Key Mediator of the Anti-Proliferative Effect of Rapamycin on Hepatocellular Carcinoma Cells. Kwon S, Ban K, Hong YK, Sung JS, Choi I., Free PMC Article | 04/16/2022 |
Long non-coding RNA PROX1-AS1 knockdown upregulates microRNA-519d-3p to promote chemosensitivity of retinoblastoma cells via targeting SOX2. | Long non-coding RNA PROX1-AS1 knockdown upregulates microRNA-519d-3p to promote chemosensitivity of retinoblastoma cells via targeting SOX2. Chen Y, Lu B, Liu L, Pan X, Jiang C, Xu H., Free PMC Article | 04/16/2022 |
Prospero homeobox 1 promotes proliferation, migration, and invasion of osteosarcoma cells and its clinical significance. | Prospero homeobox 1 promotes proliferation, migration, and invasion of osteosarcoma cells and its clinical significance. Liu D, Wang R, Wang Y, Wang Y, Wang L., Free PMC Article | 02/26/2022 |
Long noncoding RNA GAS5 accelerates diabetic wound healing and promotes lymphangiogenesis via miR-217/Prox1 axis. | Long noncoding RNA GAS5 accelerates diabetic wound healing and promotes lymphangiogenesis via miR-217/Prox1 axis. He ZY, Huang MT, Cui X, Zhou ST, Wu Y, Zhang PH, Zhou J. | 12/25/2021 |
Kaposi's sarcoma-associated herpesvirus promotes mesenchymal-to-endothelial transition by resolving the bivalent chromatin of PROX1 gene. | Kaposi's sarcoma-associated herpesvirus promotes mesenchymal-to-endothelial transition by resolving the bivalent chromatin of PROX1 gene. Ding Y, Chen W, Lu Z, Wang Y, Yuan Y., Free PMC Article | 11/27/2021 |
Long non-coding RNA DANCR modulates osteogenic differentiation by regulating the miR-1301-3p/PROX1 axis. | Long non-coding RNA DANCR modulates osteogenic differentiation by regulating the miR-1301-3p/PROX1 axis. Weng W, Di S, Xing S, Sun Z, Shen Z, Dou X, He S, Tang H, Min J. | 07/31/2021 |
Long noncoding RNA PROX1-AS1 promotes tumor progression and aggressiveness by sponging miR-647 in gastric cancer. | Long noncoding RNA PROX1-AS1 promotes tumor progression and aggressiveness by sponging miR-647 in gastric cancer. Song X, Bi Y, Guo W. | 06/26/2021 |
Two rare PROX1 variants in patients with lymphedema. | Two rare PROX1 variants in patients with lymphedema. Ricci M, Amato B, Barati S, Compagna R, Veselenyiova D, Kenanoglu S, Stuppia L, Beccari T, Baglivo M, Kurti D, Krajcovic J, Serrani R, Dundar M, Basha SH, Chiurazzi P, Bertelli M., Free PMC Article | 06/5/2021 |
lncRNAMIAT facilitates the differentiation of adiposederived mesenchymal stem cells into lymphatic endothelial cells via the miR495/Prox1 axis. | lncRNA‑MIAT facilitates the differentiation of adipose‑derived mesenchymal stem cells into lymphatic endothelial cells via the miR‑495/Prox1 axis. Dai XW, Luo W, Lv CL. | 05/15/2021 |
Slow-Cycling Cancer Stem Cells Regulate Progression and Chemoresistance in Colon Cancer. | Slow-Cycling Cancer Stem Cells Regulate Progression and Chemoresistance in Colon Cancer. Shiokawa D, Sakai H, Ohata H, Miyazaki T, Kanda Y, Sekine S, Narushima D, Hosokawa M, Kato M, Suzuki Y, Takeyama H, Kambara H, Nakagama H, Okamoto K. | 02/13/2021 |
The Impact of Transcription Factor Prospero Homeobox 1 on the Regulation of Thyroid Cancer Malignancy. | The Impact of Transcription Factor Prospero Homeobox 1 on the Regulation of Thyroid Cancer Malignancy. Rudzińska M, Czarnocka B., Free PMC Article | 02/13/2021 |
The Lymphatic Cell Environment Promotes Kaposi Sarcoma Development by Prox1-Enhanced Productive Lytic Replication of Kaposi Sarcoma Herpes Virus. | The Lymphatic Cell Environment Promotes Kaposi Sarcoma Development by Prox1-Enhanced Productive Lytic Replication of Kaposi Sarcoma Herpes Virus. Choi D, Park E, Kim KE, Jung E, Seong YJ, Zhao L, Madhavan S, Daghlian G, Lee HH, Daghlian PT, Daghlian S, Bui K, Koh CJ, Wong AK, Cho IT, Hong YK., Free PMC Article | 01/9/2021 |