| Study of the effects of Escherichia coli lipopolysaccharide on innate immunity: The expression profile of TLR4 and CD14 genes in rat liver. | Study of the effects of Escherichia coli lipopolysaccharide on innate immunity: The expression profile of TLR4 and CD14 genes in rat liver.
Al-Aalim AM, Al-Iedani AA, Hamad MA., Free PMC Article | 04/23/2022 |
| Sexual Dimorphic Role of CD14 (Cluster of Differentiation 14) in Salt-Sensitive Hypertension and Renal Injury. | Sexual Dimorphic Role of CD14 (Cluster of Differentiation 14) in Salt-Sensitive Hypertension and Renal Injury.
Fehrenbach DJ, Abais-Battad JM, Dasinger JH, Lund H, Keppel T, Zemaj J, Cherian-Shaw M, Gundry RL, Geurts AM, Dwinell MR, Mattson DL., Free PMC Article | 07/10/2021 |
| This study shows that sCD14 impairs contractile function and insulin action in primary adult rat cardiomyocytes. | Soluble CD14 inhibits contractile function and insulin action in primary adult rat cardiomyocytes.
Overhagen S, Blumensatt M, Fahlbusch P, Herzfeld de Wiza D, Müller H, Maxhera B, Akhyari P, Ouwens DM. | 12/22/2018 |
| CD 14 mRNA expression increased significantly after five days of bile duct ligation in liver, lung, spleen, and ileum. | The kinetic expression of lipopolysaccharide-binding protein and CD14 gene in obstructive jaundice.
Tsai CH, Yeh CH, Sheen-Chen SM, Huang CY, Liu YW, Huang CC, Shen SC, Tang RP. | 09/12/2015 |
| biliary drainage affects expression of inducible nitric oxide synthase, CD14 and TGR5 expression in obstructive jaundice rats | Effect of biliary drainage on inducible nitric oxide synthase, CD14 and TGR5 expression in obstructive jaundice rats.
Wang ZK, Xiao JG, Huang XF, Gong YC, Li W., Free PMC Article | 01/11/2014 |
| Hepatic ischemia-reperfusion injury up-regulated CD14 and TLR4 gene expression in Kupffer cells, and subsequently activated NF-kappabeta to produce cytokines. | The role of CD14 and Toll-like receptor 4 of Kupffer cells in hepatic ischemia-reperfusion injury in rats.
Luan X, Liu Y, Li M. | 09/8/2012 |
| Show that pineal glands possess both CD14 and toll-like receptor 4 (TLR4), membrane proteins that bind LPS and trigger the NFKB pathway. | TLR4 and CD14 receptors expressed in rat pineal gland trigger NFKB pathway.
da Silveira Cruz-Machado S, Carvalho-Sousa CE, Tamura EK, Pinato L, Cecon E, Fernandes PA, de Avellar MC, Ferreira ZS, Markus RP. | 01/1/2011 |
| CD14 and TLR4 were not detected in healthy periapical tissue but strongly positive in inflammatory periapical tissue. | [Expression of lipopolysaccharide receptors CD14 and TLR4 in a model of rat molar apical periodontitis].
Zhang C, Hou BX. | 07/5/2010 |
| Burn injury-induced mitochondrial damage in cardiomyocytes was prevented in CD14 knockout mice. Burn injury produces CD14-dependent mitochondrial damage via oxidative stress in myocardium. | Burn serum causes a CD14-dependent mitochondrial damage in primary cardiomyocytes.
Zang QS, Maass DL, Wigginton JG, Barber RC, Martinez B, Idris AH, Horton JW, Nwariaku FE., Free PMC Article | 06/28/2010 |
| Splenic tissue concentrations of alpha(2A)-AR, PDE4D, CD14, and TLR4 were significantly increased in septic aged rats as compared to aged sham rats and septic young rats. | Aging-related hyperinflammation in endotoxemia is mediated by the alpha2A-adrenoceptor and CD14/TLR4 pathways.
Leong J, Zhou M, Jacob A, Wang P., Free PMC Article | 05/10/2010 |
| Acute cerebral hemorrhage results in endotoxemia and widespread increases in CD14 and IL-1beta expression. | Increased serum endotoxin and elevated CD14 and IL-1beta expression in a rat model of cerebrogenic multiple organ dysfunction syndrome.
Qu C, Guo S, Guo H, Wang C, Ma L, He Y, Wang L, Lou J, Wang X. | 02/22/2010 |
| LPS/CD14/TLR4-mediated inflammation has a role in necrotizing enterocolitis in humans and rats | Role of LPS/CD14/TLR4-mediated inflammation in necrotizing enterocolitis: pathogenesis and therapeutic implications.
Chan KL, Wong KF, Luk JM., Free PMC Article | 02/1/2010 |
| high affinity interactions between the palmitoyl-oleoyl-phosphatidylglycerol and the Toll-like receptor 4-interacting proteins CD14 and MD-2. | Anionic pulmonary surfactant phospholipids inhibit inflammatory responses from alveolar macrophages and U937 cells by binding the lipopolysaccharide-interacting proteins CD14 and MD-2.
Kuronuma K, Mitsuzawa H, Takeda K, Nishitani C, Chan ED, Kuroki Y, Nakamura M, Voelker DR., Free PMC Article | 01/21/2010 |
| The expressions of TNF-alpha, TLR4, and CD14 increased in the non-alcoholic steatohepatitis (NASH) model, suggesting that TLR4 and CD14-mediated endotoxin liver damage may also occur in NASH. | Innate immune reactivity of the liver in rats fed a choline-deficient L-amino-acid-defined diet.
Kawaratani H, Tsujimoto T, Kitazawa T, Kitade M, Yoshiji H, Uemura M, Fukui H., Free PMC Article | 01/21/2010 |
| CD14 glycoprotein is present on the cell membranes of vascular smooth muscle cells of rat aorta, where it acts as a lipopolysaccharide receptor. | CD14 glycoprotein expressed in vascular smooth muscle cells.
Choi HC, Lee KY. | 01/21/2010 |
| Expression of CD14 protein and its gene in liver sinusoidal endothelial cells during endotoxemia. | Expression of CD14 protein and its gene in liver sinusoidal endothelial cells during endotoxemia.
Gong JP, Dai LL, Liu CA, Wu CX, Shi YJ, Li SW, Li XH., Free PMC Article | 01/21/2010 |
| the CD14 antigen system appeared to be an early trigger for Kupffer cell activation followed by induction of inflammatory cytokine interleukin-1beta synthesis leading to hepatic injury after partial hepatectomy | High expression of the CD14 gene and interleukin-1beta gene in the liver and lungs of cirrhotic rats after partial hepatectomy.
Takeda Y, Arii S, Mori A, Imamura M. | 01/21/2010 |
| in kupffer cells, increase of TLR4, CD14 expression may be induced by LPS within 1-3 hours, and further increase of TLR4, CD14 expression is correlated with the cytokines produced by KCs. | The effect of lipopolysaccharides on the expression of CD14 and TLR4 in rat Kupffer cells.
Feng JM, Shi JQ, Liu YS. | 01/21/2010 |
| Increase of CD14 mRNA expression may result in greater sensitivity to endotoxin and thus lead to liver injury. | [Expression of lipopolysaccharide binding protein and lipopolysaccharide receptor CD14 in experimental alcoholic liver disease].
Zuo G, He S, Liu C, Gong J. | 01/21/2010 |
| Although microglial-derived CD14 does not contribute to early events triggered by intrastriatal endotoxin treatment, it modulates the duration of inflammation within the cerebral tissue. | Endotoxemia prevents the cerebral inflammatory wave induced by intraparenchymal lipopolysaccharide injection: role of glucocorticoids and CD14.
Nadeau S, Rivest S. | 01/21/2010 |
| LPS-induced decreased PS expression in hepatocytes and SECs is mediated by MEK/ERK signaling and NFkappaB activation and that membrane-bound CD14 and TLR-4 are involved in this mechanism | Lipopolysaccharide-induced decreased protein S expression in liver cells is mediated by MEK/ERK signaling and NFkappaB activation: involvement of membrane-bound CD14 and toll-like receptor-4.
Hayashi T, Kishiwada M, Fujii K, Yuasa H, Nishioka J, Ido M, Gabazza EC, Suzuki K. | 01/21/2010 |
| Ethanol administration led to a significant synthesis of endotoxin receptor CD14 protein and its gene expression in Kupffer cells, which maybe result in the pathological changes of liver tissue and hepatic functional damages. | Synthesis of endotoxin receptor CD14 protein in Kupffer cells and its role in alcohol-induced liver disease.
Dai LL, Gong JP, Zuo GQ, Wu CX, Shi YJ, Li XH, Peng Y, Deng W, Li SW, Liu CA., Free PMC Article | 01/21/2010 |