Circular RNA hsa_circ_0050386 suppresses non-small cell lung cancer progression via regulating the SRSF3/FN1 axis. | Circular RNA hsa_circ_0050386 suppresses non-small cell lung cancer progression via regulating the SRSF3/FN1 axis. Chen J, Rao B, Huang Z, Xie C, Yu Y, Yang B, Wu D, Wang D, Qiu F, Zhou Y, Deng Y, Lu J., Free PMC Article | 01/27/2024 |
An anti-PD-1 antisense oligonucleotide promotes the expression of soluble PD-1 by blocking the interaction between SRSF3 and an exonic splicing enhancer of PD-1 exon 3. | An anti-PD-1 antisense oligonucleotide promotes the expression of soluble PD-1 by blocking the interaction between SRSF3 and an exonic splicing enhancer of PD-1 exon 3. Wang X, Yan L, Guo J, Jia R. | 01/4/2024 |
Homeobox B9 Promotes Colon Cancer Progression by Targeting SRSF3. | Homeobox B9 Promotes Colon Cancer Progression by Targeting SRSF3. Yuan L, Cheng F, Wu Z, Li X, Shen W. | 09/6/2023 |
SRSF3/AMOTL1 splicing axis promotes the tumorigenesis of nasopharyngeal carcinoma through regulating the nucleus translocation of YAP1. | SRSF3/AMOTL1 splicing axis promotes the tumorigenesis of nasopharyngeal carcinoma through regulating the nucleus translocation of YAP1. Xu XC, Jiang JX, Zhou YQ, He S, Liu Y, Li YQ, Wei PP, Bei JX, Sun J, Luo CL., Free PMC Article | 08/11/2023 |
Genetic compensation response could exist in colorectal cancer: UPF3A upregulates the oncogenic homologue gene SRSF3 expression corresponding to SRSF6 to promote colorectal cancer metastasis. | Genetic compensation response could exist in colorectal cancer: UPF3A upregulates the oncogenic homologue gene SRSF3 expression corresponding to SRSF6 to promote colorectal cancer metastasis. Xu W, Ou W, Feng Y, Xu Q, Yang Y, Cui L, Du P. | 04/21/2023 |
Splicing factor SRSF3 promotes the progression of cervical cancer through regulating DDX5. | Splicing factor SRSF3 promotes the progression of cervical cancer through regulating DDX5. Che Y, Bai M, Lu K, Fu L. | 01/28/2023 |
SRSF3 Restriction Eases Cervical Cancer Cell Viability and Metastasis via Adjusting PI3K/AKT/mTOR Signaling Pathway. | SRSF3 Restriction Eases Cervical Cancer Cell Viability and Metastasis via Adjusting PI3K/AKT/mTOR Signaling Pathway. Zhang L, Li J, Zhang L., Free PMC Article | 10/22/2022 |
Hepatocyte Deletion of IGF2 Prevents DNA Damage and Tumor Formation in Hepatocellular Carcinoma. | Hepatocyte Deletion of IGF2 Prevents DNA Damage and Tumor Formation in Hepatocellular Carcinoma. Kumar D, Das M, Oberg A, Sahoo D, Wu P, Sauceda C, Jih L, Ellies LG, Langiewicz MT, Sen S, Webster NJG., Free PMC Article | 08/6/2022 |
LINC01210 promotes malignant phenotypes of colorectal cancer through epigenetically upregulating SRSF3. | LINC01210 promotes malignant phenotypes of colorectal cancer through epigenetically upregulating SRSF3. Luo J, Gao K, Chen M, Tian B. | 06/11/2022 |
Multiple Phosphorylations of SR Protein SRSF3 and Its Binding to m(6)A Reader YTHDC1 in Human Cells. | Multiple Phosphorylations of SR Protein SRSF3 and Its Binding to m(6)A Reader YTHDC1 in Human Cells. Tatsuno T, Ishigaki Y., Free PMC Article | 05/21/2022 |
Oncogenic lncRNA ZNFX1 antisense RNA 1 promotes osteosarcoma cells proliferation and metastasis by stabilizing serine and argininerich splicing factor 3. | Oncogenic lncRNA ZNFX1 antisense RNA 1 promotes osteosarcoma cells proliferation and metastasis by stabilizing serine and arginine‑rich splicing factor 3. Zhang Y, Xu W, Wang Y, Li J, He G, Guan M, Zeng X, Bian W, Song Y, Liu J., Free PMC Article | 04/16/2022 |
Inhibition of SRSF3 Alleviates Proliferation and Migration of Gastric Cancer Cells by Regulating the PI3K/AKT/mTOR Signalling Pathway. | Inhibition of SRSF3 Alleviates Proliferation and Migration of Gastric Cancer Cells by Regulating the PI3K/AKT/mTOR Signalling Pathway. Xie J, Sun Y, Xu Q. | 02/19/2022 |
Identification of SRSF3 target mRNAs using inducible TRIBE. | Identification of SRSF3 target mRNAs using inducible TRIBE. Jin S, Xue Z, Zhang J, Wang Z, Zhang J, Chen D, Liu W, Lin J. | 01/29/2022 |
PPM1G promotes the progression of hepatocellular carcinoma via phosphorylation regulation of alternative splicing protein SRSF3. | PPM1G promotes the progression of hepatocellular carcinoma via phosphorylation regulation of alternative splicing protein SRSF3. Chen D, Zhao Z, Chen L, Li Q, Zou J, Liu S., Free PMC Article | 01/29/2022 |
Regulated splicing of large exons is linked to phase-separation of vertebrate transcription factors. | Regulated splicing of large exons is linked to phase-separation of vertebrate transcription factors. Kawachi T, Masuda A, Yamashita Y, Takeda JI, Ohkawara B, Ito M, Ohno K., Free PMC Article | 01/8/2022 |
A quantitative map of human primary microRNA processing sites. | A quantitative map of human primary microRNA processing sites. Kim K, Baek SC, Lee YY, Bastiaanssen C, Kim J, Kim H, Kim VN. | 09/4/2021 |
The SRSF3-MBNL1-Acin1 circuit constitutes an emerging axis to lessen DNA fragmentation in colorectal cancer via an alternative splicing mechanism. | The SRSF3-MBNL1-Acin1 circuit constitutes an emerging axis to lessen DNA fragmentation in colorectal cancer via an alternative splicing mechanism. Chen YS, Liu CW, Lin YC, Tsai CY, Yang CH, Lin JC., Free PMC Article | 08/21/2021 |
SRSF3 Is a Critical Requirement for Inclusion of Exon 3 of BIS Pre-mRNA. | SRSF3 Is a Critical Requirement for Inclusion of Exon 3 of BIS Pre-mRNA. Baek JY, Yun HH, Jung SY, Lee J, Yoo K, Lee JH., Free PMC Article | 04/3/2021 |
B7-H3 is spliced by SRSF3 in colorectal cancer. | B7-H3 is spliced by SRSF3 in colorectal cancer. Zhang C, Chen Y, Li F, Yang M, Meng F, Zhang Y, Chen W, Wang W., Free PMC Article | 03/13/2021 |
Splicing machinery dysregulation drives glioblastoma development/aggressiveness: oncogenic role of SRSF3. | Splicing machinery dysregulation drives glioblastoma development/aggressiveness: oncogenic role of SRSF3. Fuentes-Fayos AC, Vázquez-Borrego MC, Jiménez-Vacas JM, Bejarano L, Pedraza-Arévalo S, L-López F, Blanco-Acevedo C, Sánchez-Sánchez R, Reyes O, Ventura S, Solivera J, Breunig JJ, Blasco MA, Gahete MD, Castaño JP, Luque RM., Free PMC Article | 03/6/2021 |
Results have identified SRSF3 as the trans-RNA splicing factor responsible for mediating alternative RNA splicing (AS) of CPEB2 through inclusion of exon 4 via binding at the cis-RNA pentameric exonic splicing enhancers. These findings demonstrate that SRSF3 modulates CPEB2 AS to induce the expression of the CPEB2B isoform that drives TNBC phenotypes correlating with aggressive human breast cancer. | Serine/Arginine-Rich Splicing Factor 3 Modulates the Alternative Splicing of Cytoplasmic Polyadenylation Element Binding Protein 2. DeLigio JT, Stevens SC, Nazario-Muñoz GS, MacKnight HP, Doe KK, Chalfant CE, Park MA., Free PMC Article | 06/20/2020 |
SRSF3 was frequently upregulated in clinical glioma specimens and was associated with tumor progression and poor prognosis. SRSF3 expression promoted cell proliferation, self-renewal, and tumorigenesis. Transcriptomic profiling found more than 1,000 SRSF3-affected alternative splicing events. SRSF3-regulated AS of ETV1 and NDE1 markedly increased their oncogenic activity in GSCs. | SRSF3-Regulated RNA Alternative Splicing Promotes Glioblastoma Tumorigenicity by Affecting Multiple Cellular Processes. Song X, Wan X, Huang T, Zeng C, Sastry N, Wu B, James CD, Horbinski C, Nakano I, Zhang W, Hu B, Cheng SY., Free PMC Article | 06/6/2020 |
This study showed that reduced SRSF3 expression could promote cellular senescence through its APA-dependent function, largely extending our mechanistic understanding in splicing factor regulated cellular senescence. | Alternative polyadenylation dependent function of splicing factor SRSF3 contributes to cellular senescence. Shen T, Li H, Song Y, Li L, Lin J, Wei G, Ni T., Free PMC Article | 05/30/2020 |
Studied association of hnRNP L Alternative Exon 7 and serine and arginine rich splicing factor 3 (SRSF3) in head and neck squamous cell carcinoma(HNSCC); found inclusion of hnRNP L alternative exon 7 is associated with good prognosis and inhibited by oncogene SRSF3 in HNSCC. | Inclusion of hnRNP L Alternative Exon 7 Is Associated with Good Prognosis and Inhibited by Oncogene SRSF3 in Head and Neck Squamous Cell Carcinoma. Xu L, Shen J, Jia J, Jia R., Free PMC Article | 05/2/2020 |
Publicly available data from paired normal and tumor tissues in hepatocellular carcinoma (HCC) and results from patients with HCC suggest that SRSF3 and SF3B4 possess an inverse relationship. SRSF3 is a key molecule for determining SF3B4 levels in HCC cells | SRSF3 Depletion Leads to an Increase in SF3B4 Expression in SNU-368 HCC Cells. Lee J, Seo G, Hur W, Yoon SK, Nam SW, Lee JH. | 04/11/2020 |