| Site 1 protease aggravates acute kidney injury by promoting tubular epithelial cell ferroptosis through SIRT3-SOD2-mtROS signaling. | Site 1 protease aggravates acute kidney injury by promoting tubular epithelial cell ferroptosis through SIRT3-SOD2-mtROS signaling.
Xie S, Zou W, Liu S, Yang Q, Hu T, Zhu WP, Tang H, Wang C. | 04/15/2024 |
| Downregulation of Sirt3 contributes to beta-cell dedifferentiation via FoxO1 in type 2 diabetic mellitus. | Downregulation of Sirt3 contributes to β-cell dedifferentiation via FoxO1 in type 2 diabetic mellitus.
Nie Y, Zhang Y, Liu S, Xu Z, Xia C, Du L, Yin X, Wang J. | 03/29/2024 |
| Role of Argininosuccinate Synthase 1 -Dependent L-Arginine Biosynthesis in the Protective Effect of Endothelial Sirtuin 3 Against Atherosclerosis. | Role of Argininosuccinate Synthase 1 -Dependent L-Arginine Biosynthesis in the Protective Effect of Endothelial Sirtuin 3 Against Atherosclerosis.
Cao X, Wu VWY, Han Y, Hong H, Wu Y, Kong APS, Lui KO, Tian XY., Free PMC Article | 03/28/2024 |
| Sirtuin 3 (SIRT3) improves sevoflurane-induced postoperative cognitive impairment by regulating mitochondrial oxidative stress. | Sirtuin 3 (SIRT3) improves sevoflurane-induced postoperative cognitive impairment by regulating mitochondrial oxidative stress.
Dai C, Fu C, Yi Z, Guan X, Deng J. | 03/14/2024 |
| Sirt3 Regulates Proliferation and Progesterone Production in Leydig Cells via Suppression of Reactive Oxygen Species. | Sirt3 Regulates Proliferation and Progesterone Production in Leydig Cells via Suppression of Reactive Oxygen Species.
Matoba H, Fujii C, Maruyama K, Kawakubo M, Momose M, Sano K, Imamura H, Kurihara H, Nakayama J. | 02/27/2024 |
| Sirtuin 3 is required for the dexmedetomidine-mediated alleviation of inflammation and oxidative stress in nephritis. | Sirtuin 3 is required for the dexmedetomidine-mediated alleviation of inflammation and oxidative stress in nephritis.
Lu K, Li X, Wu J., Free PMC Article | 02/27/2024 |
| Sirtuin3 promotes the degradation of hepatic Z alpha-1 antitrypsin through lipophagy. | Sirtuin3 promotes the degradation of hepatic Z alpha-1 antitrypsin through lipophagy.
Poole B, Oshins R, Huo Z, Aranyos A, West J, Duarte S, Clark VC, Beduschi T, Zarrinpar A, Brantly M, Khodayari N., Free PMC Article | 02/21/2024 |
| The SIRT3-ATAD3A axis regulates MAM dynamics and mitochondrial calcium homeostasis in cardiac hypertrophy. | The SIRT3-ATAD3A axis regulates MAM dynamics and mitochondrial calcium homeostasis in cardiac hypertrophy.
Li Z, Hu O, Xu S, Lin C, Yu W, Ma D, Lu J, Liu P., Free PMC Article | 02/16/2024 |
| Electroacupuncture Mediates Fat Metabolism and Autophagy via a Sirt3-Dependent Mechanism in Mice Fed High-Fat Diet. | Electroacupuncture Mediates Fat Metabolism and Autophagy via a Sirt3-Dependent Mechanism in Mice Fed High-Fat Diet.
Wang M, Sun Z, Ou Y, Ge W, Yuan M, Xu B. | 02/15/2024 |
| Sirt3 Deletion Increases Inflammation and Mortality in Polymicrobial Sepsis. | Sirt3 Deletion Increases Inflammation and Mortality in Polymicrobial Sepsis.
Labiner HE, Sas KM, Baur JA, Sims CA., | 12/1/2023 |
| 2,8-Dihydroxyadenine-induced nephropathy causes hexosylceramide accumulation with increased mTOR signaling, reduced levels of protective SirT3 expression and impaired renal mitochondrial function. | 2,8-Dihydroxyadenine-induced nephropathy causes hexosylceramide accumulation with increased mTOR signaling, reduced levels of protective SirT3 expression and impaired renal mitochondrial function.
Moellmann J, Krueger K, Wong DWL, Klinkhammer BM, Buhl EM, Dehairs J, Swinnen JV, Noels H, Jankowski J, Lebherz C, Boor P, Marx N, Lehrke M. | 11/16/2023 |
| Intermittent fasting promotes adipocyte mitochondrial fusion through Sirt3-mediated deacetylation of Mdh2. | Intermittent fasting promotes adipocyte mitochondrial fusion through Sirt3-mediated deacetylation of Mdh2.
Li Y, Liang J, Tian X, Chen Q, Zhu L, Wang H, Liu Z, Dai X, Bian C, Sun C. | 11/1/2023 |
| Restoration of SIRT3 gene expression by airway delivery resolves age-associated persistent lung fibrosis in mice. | Restoration of SIRT3 gene expression by airway delivery resolves age-associated persistent lung fibrosis in mice.
Rehan M, Kurundkar D, Kurundkar AR, Logsdon NJ, Smith SR, Chanda D, Bernard K, Sanders YY, Deshane JS, Dsouza KG, Rangarajan S, Zmijewski JW, Thannickal VJ., Free PMC Article | 10/20/2023 |
| SIRT3-dependent mitochondrial redox homeostasis mitigates CHK1 inhibition combined with gemcitabine treatment induced cardiotoxicity in hiPSC-CMs and mice. | SIRT3-dependent mitochondrial redox homeostasis mitigates CHK1 inhibition combined with gemcitabine treatment induced cardiotoxicity in hiPSC-CMs and mice.
Chen JW, Shan TK, Wei TW, Jiang QQ, Du C, Gu LF, Yang TT, Zhou LH, Wang SB, Bao YL, Wang H, Ji Y, Xie LP, Gu AH, Sun CQ, Wang QM, Wang LS. | 10/13/2023 |
| Sirt3 deficiency promotes endothelial dysfunction and aggravates renal injury. | Sirt3 deficiency promotes endothelial dysfunction and aggravates renal injury.
Pezzotta A, Perico L, Corna D, Morigi M, Remuzzi G, Benigni A, Imberti B., Free PMC Article | 10/12/2023 |
| SIRT3 regulates mitophagy in liver fibrosis through deacetylation of PINK1/NIPSNAP1. | SIRT3 regulates mitophagy in liver fibrosis through deacetylation of PINK1/NIPSNAP1.
Li R, Wang Z, Wang Y, Sun R, Zou B, Tian X, Liu D, Zhao X, Zhou J, Zhao Y, Yao J. | 09/25/2023 |
| SIRT3 Regulates Clearance of Apoptotic Cardiomyocytes by Deacetylating Frataxin. | SIRT3 Regulates Clearance of Apoptotic Cardiomyocytes by Deacetylating Frataxin.
Gao J, Huang C, Kong L, Zhou W, Sun M, Wei T, Shen W., Free PMC Article | 09/20/2023 |
| Sirtuin-3 activates the mitochondrial unfolded protein response and reduces cerebral ischemia/reperfusion injury. | Sirtuin-3 activates the mitochondrial unfolded protein response and reduces cerebral ischemia/reperfusion injury.
Xiaowei X, Qian X, Dingzhou Z., Free PMC Article | 09/19/2023 |
| SIRT3 alleviates sepsis-induced acute lung injury by inhibiting pyroptosis via regulating the deacetylation of FoxO3a. | SIRT3 alleviates sepsis-induced acute lung injury by inhibiting pyroptosis via regulating the deacetylation of FoxO3a.
Wu Z, Wang Y, Lu S, Yin L, Dai L. | 09/18/2023 |
| Sirtuin 3 controls cardiac energetics and protects against oxidative stress in electromagnetic radiation-induced cardiomyopathy. | Sirtuin 3 controls cardiac energetics and protects against oxidative stress in electromagnetic radiation-induced cardiomyopathy.
Niu T, Zhi Y, Wei L, Liu W, Ju X, Pi W, Fu Z, Tong H, Hu H, Dong J. | 09/6/2023 |
| SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes. | SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes.
Chang Y, Wang C, Zhu J, Zheng S, Sun S, Wu Y, Jiang X, Li L, Ma R, Li G., Free PMC Article | 07/27/2023 |
| SIRT3-and FAK-mediated acetylation-phosphorylation crosstalk of NFATc1 regulates N[epsilon]-carboxymethyl-lysine-induced vascular calcification in diabetes mellitus. | SIRT3-and FAK-mediated acetylation-phosphorylation crosstalk of NFATc1 regulates N(ε)-carboxymethyl-lysine-induced vascular calcification in diabetes mellitus.
Sun Z, Zhang L, Yin K, Zang G, Qian Y, Mao X, Li L, Jing Q, Wang Z. | 07/25/2023 |
| Sirt3 improves monosodium urate crystal-induced inflammation by suppressing Acod1 expression. | Sirt3 improves monosodium urate crystal-induced inflammation by suppressing Acod1 expression.
Lv L, Jiang H, Song D, Zhou X, Chen F, Ren L, Xie Y, Zeng M., Free PMC Article | 07/21/2023 |
| Macrophage/Microglia Sirt3 Contributes to the Anti-inflammatory Effects of Resveratrol Against Experimental Intracerebral Hemorrhage in Mice. | Macrophage/Microglia Sirt3 Contributes to the Anti-inflammatory Effects of Resveratrol Against Experimental Intracerebral Hemorrhage in Mice.
Sun J, Pu C, Yang E, Zhang H, Feng Y, Luo P, Yang Y, Zhang L, Li X, Jiang X, Dai S. | 07/13/2023 |
| SIRT3 Deficiency Enhances Ferroptosis and Promotes Cardiac Fibrosis via p53 Acetylation. | SIRT3 Deficiency Enhances Ferroptosis and Promotes Cardiac Fibrosis via p53 Acetylation.
Su H, Cantrell AC, Chen JX, Gu W, Zeng H., Free PMC Article | 07/12/2023 |