| Study on the Role and Mechanism of SLC3A2 in Tumor-Associated Macrophage Polarization and Bladder Cancer Cells Growth. | Study on the Role and Mechanism of SLC3A2 in Tumor-Associated Macrophage Polarization and Bladder Cancer Cells Growth.
Wu P, Zhao L, Kong G, Song B., Free PMC Article | 04/26/2024 |
| Structure and mechanisms of transport of human Asc1/CD98hc amino acid transporter. | Structure and mechanisms of transport of human Asc1/CD98hc amino acid transporter.
Rullo-Tubau J, Martinez-Molledo M, Bartoccioni P, Puch-Giner I, Arias Á, Saen-Oon S, Stephan-Otto Attolini C, Artuch R, Díaz L, Guallar V, Errasti-Murugarren E, Palacín M, Llorca O., Free PMC Article | 04/10/2024 |
| Identification and validation of RNA-binding protein SLC3A2 regulates melanocyte ferroptosis in vitiligo by integrated analysis of single-cell and bulk RNA-sequencing. | Identification and validation of RNA-binding protein SLC3A2 regulates melanocyte ferroptosis in vitiligo by integrated analysis of single-cell and bulk RNA-sequencing.
Zhang J, Xiang F, Ding Y, Hu W, Wang H, Zhang X, Lei Z, Li T, Wang P, Kang X., Free PMC Article | 03/6/2024 |
| Effect of disulfidptosis-related genes SLC3A2, SLC7A11 and FLNB polymorphisms on risk of autoimmune thyroiditis in a Chinese population. | Effect of disulfidptosis-related genes SLC3A2, SLC7A11 and FLNB polymorphisms on risk of autoimmune thyroiditis in a Chinese population.
Wang Q, Xiao Z, Hou Z, Li D. | 02/27/2024 |
| Ancient dormant virus remnant ERVW-1 drives ferroptosis via degradation of GPX4 and SLC3A2 in schizophrenia. | Ancient dormant virus remnant ERVW-1 drives ferroptosis via degradation of GPX4 and SLC3A2 in schizophrenia.
Zhang D, Wu X, Xue X, Li W, Zhou P, Lv Z, Zhao K, Zhu F., Free PMC Article | 02/21/2024 |
| SLC3A2 N-glycosylation and Golgi remodeling regulate SLC7A amino acid exchangers and stress mitigation. | SLC3A2 N-glycosylation and Golgi remodeling regulate SLC7A amino acid exchangers and stress mitigation.
Zhang C, Shafaq-Zadah M, Pawling J, Hesketh GG, Dransart E, Pacholczyk K, Longo J, Gingras AC, Penn LZ, Johannes L, Dennis JW., Free PMC Article | 01/29/2024 |
| SLC3A2 promotes tumor-associated macrophage polarization through metabolic reprogramming in lung cancer. | SLC3A2 promotes tumor-associated macrophage polarization through metabolic reprogramming in lung cancer.
Li Z, Chen S, He X, Gong S, Sun L, Weng L., Free PMC Article | 06/5/2023 |
| CD98 regulates the phosphorylation of HER2 and a bispecific anti-HER2/CD98 antibody inhibits the growth signal of human breast cancer cells. | CD98 regulates the phosphorylation of HER2 and a bispecific anti-HER2/CD98 antibody inhibits the growth signal of human breast cancer cells.
Yamasaki A, Maruyama-Takahashi K, Nishida K, Okazaki S, Okita K, Akiyama Y, Suzuki H, Endo Y, Masuko K, Masuko T, Tomioka Y. | 05/8/2023 |
| Identification of CD98 as a Novel Biomarker for HIV-1 Permissiveness and Latent Infection. | Identification of CD98 as a Novel Biomarker for HIV-1 Permissiveness and Latent Infection.
Zhang W, Zhou M, Chen C, Wu S, Wang L, Xia B, Liu J, Ma X, Pan T, Zhang H, Li L, Liu B., Free PMC Article | 03/2/2023 |
| HCMV-miR-US33-5p promotes apoptosis of aortic vascular smooth muscle cells by targeting EPAS1/SLC3A2 pathway. | HCMV-miR-US33-5p promotes apoptosis of aortic vascular smooth muscle cells by targeting EPAS1/SLC3A2 pathway.
Dong J, Li S, Lu Z, Du P, Liu G, Li M, Ma C, Zhou J, Bao J., Free PMC Article | 06/11/2022 |
| Polarity protein SCRIB interacts with SLC3A2 to regulate proliferation and tamoxifen resistance in ER+ breast cancer. | Polarity protein SCRIB interacts with SLC3A2 to regulate proliferation and tamoxifen resistance in ER+ breast cancer.
Saito Y, Matsuda S, Ohnishi N, Endo K, Ashitani S, Ohishi M, Ueno A, Tomita M, Ueda K, Soga T, Muthuswamy SK., Free PMC Article | 05/21/2022 |
| Expression profile of CD98 heavy chain and L-type amino acid transporter 1 and its prognostic significance in colorectal cancer. | Expression profile of CD98 heavy chain and L-type amino acid transporter 1 and its prognostic significance in colorectal cancer.
Lee D, Kim HS, Kim HU, Song HJ, Lee C, Kim DY, Chun HM, Jang WY, Jang B. | 03/26/2022 |
| SLC3A2 inhibits ferroptosis in laryngeal carcinoma via mTOR pathway. | SLC3A2 inhibits ferroptosis in laryngeal carcinoma via mTOR pathway.
Wu F, Xiong G, Chen Z, Lei C, Liu Q, Bai Y., Free PMC Article | 01/29/2022 |
| The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-2. | The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-2.
Maimaiti M, Sakamoto S, Sugiura M, Kanesaka M, Fujimoto A, Matsusaka K, Xu M, Ando K, Saito S, Wakai K, Imamura Y, Nakayama K, Kanai Y, Kaneda A, Ikehara Y, Ikeda JI, Anzai N, Ichikawa T., Free PMC Article | 11/6/2021 |
| Plasmodium vivax binds host CD98hc (SLC3A2) to enter immature red blood cells. | Plasmodium vivax binds host CD98hc (SLC3A2) to enter immature red blood cells.
Malleret B, El Sahili A, Tay MZ, Carissimo G, Ong ASM, Novera W, Lin J, Suwanarusk R, Kosaisavee V, Chu TTT, Sinha A, Howland SW, Fan Y, Gruszczyk J, Tham WH, Colin Y, Maurer-Stroh S, Snounou G, Ng LFP, Chan JKY, Chacko AM, Lescar J, Chandramohanadas R, Nosten F, Russell B, Rénia L. | 09/18/2021 |
| Expression of LAT1 and 4F2hc in Gastroenteropancreatic Neuroendocrine Neoplasms. | Expression of LAT1 and 4F2hc in Gastroenteropancreatic Neuroendocrine Neoplasms.
Horita Y, Kaira K, Kawasaki T, Mihara Y, Sakuramoto S, Yamaguchi S, Okamoto K, Ryozawa S, Kanai Y, Yasuda M, Hamaguchi T., Free PMC Article | 09/11/2021 |
| Targeting SLC3A2 subunit of system XC(-) is essential for m(6)A reader YTHDC2 to be an endogenous ferroptosis inducer in lung adenocarcinoma. | Targeting SLC3A2 subunit of system X(C)(-) is essential for m(6)A reader YTHDC2 to be an endogenous ferroptosis inducer in lung adenocarcinoma.
Ma L, Zhang X, Yu K, Xu X, Chen T, Shi Y, Wang Y, Qiu S, Guo S, Cui J, Miao Y, Tian X, Du L, Yu Y, Xia J, Wang J. | 08/21/2021 |
| Overexpression of membranal SLC3A2 regulates the proliferation of oral squamous cancer cells and affects the prognosis of oral cancer patients. | Overexpression of membranal SLC3A2 regulates the proliferation of oral squamous cancer cells and affects the prognosis of oral cancer patients.
Liang J, Sun Z. | 04/24/2021 |
| Abnormalities in the genes that encode Large Amino Acid Transporters increase the risk of Autism Spectrum Disorder. | Abnormalities in the genes that encode Large Amino Acid Transporters increase the risk of Autism Spectrum Disorder.
Cascio L, Chen CF, Pauly R, Srikanth S, Jones K, Skinner CD, Stevenson RE, Schwartz CE, Boccuto L., Free PMC Article | 03/27/2021 |
| Sub-Nanometer Cryo-EM Density Map of the Human Heterodimeric Amino Acid Transporter 4F2hc-LAT2. | Sub-Nanometer Cryo-EM Density Map of the Human Heterodimeric Amino Acid Transporter 4F2hc-LAT2.
Jeckelmann JM, Fotiadis D., Free PMC Article | 03/6/2021 |
| The Heavy Chain 4F2hc Modulates the Substrate Affinity and Specificity of the Light Chains LAT1 and LAT2. | The Heavy Chain 4F2hc Modulates the Substrate Affinity and Specificity of the Light Chains LAT1 and LAT2.
Kantipudi S, Jeckelmann JM, Ucurum Z, Bosshart PD, Fotiadis D., Free PMC Article | 02/27/2021 |
| Co-Expression Effect of SLC7A5/SLC3A2 to Predict Response to Endocrine Therapy in Oestrogen-Receptor-Positive Breast Cancer. | Co-Expression Effect of SLC7A5/SLC3A2 to Predict Response to Endocrine Therapy in Oestrogen-Receptor-Positive Breast Cancer.
Alfarsi LH, El-Ansari R, Craze ML, Masisi BK, Mohammed OJ, Ellis IO, Rakha EA, Green AR., Free PMC Article | 01/9/2021 |
| CD98hc (SLC3A2) sustains amino acid and nucleotide availability for cell cycle progression. | CD98hc (SLC3A2) sustains amino acid and nucleotide availability for cell cycle progression.
Cano-Crespo S, Chillarón J, Junza A, Fernández-Miranda G, García J, Polte C, R de la Ballina L, Ignatova Z, Yanes Ó, Zorzano A, Stephan-Otto Attolini C, Palacín M., Free PMC Article | 11/21/2020 |
| SLC3A2/CD98hc, autophagy and tumor radioresistance: a link confirmed. | SLC3A2/CD98hc, autophagy and tumor radioresistance: a link confirmed.
Digomann D, Linge A, Dubrovska A., Free PMC Article | 08/22/2020 |
| This study reports the crystal structure of the murine CD98hc extracellular domain and a comprehensive comparison with its human ortholog, revealing only one conserved surface patch that is neither shielded by glycosylation nor by the cell membrane with an accessible surface area typical for an antibody epitope. | Structural differences between the ectodomains of murine and human CD98hc.
Deuschle FC, Schiefner A, Skerra A. | 05/23/2020 |