| HNF4alpha ubiquitination mediated by Peli1 impairs FAO and accelerates pressure overload-induced myocardial hypertrophy. | HNF4α ubiquitination mediated by Peli1 impairs FAO and accelerates pressure overload-induced myocardial hypertrophy.
Hou Y, Shi P, Du H, Zhu C, Tang C, Que L, Zhu G, Liu L, Chen Q, Li C, Shao G, Li Y, Li J., Free PMC Article | 02/17/2024 |
| Novel approaches to determine the functional role of cardiomyocyte specific E3 ligase, Pellino-1 following myocardial infarction. | Novel approaches to determine the functional role of cardiomyocyte specific E3 ligase, Pellino-1 following myocardial infarction.
Pradeep SR, Thirunavukkarasu M, Accorsi D, Swaminathan S, Lim ST, Cernuda B, Kemerley A, Hubbard J, Campbell J, Wilson RL, Coca-Soliz V, Tapias L, Selvaraju V, Jellison ER, Yee SP, Palesty JA, Maulik N. | 11/18/2023 |
| Role of Pellino-1 in Inflammation and Cardioprotection following Severe Sepsis: A Novel Mechanism in a Murine Severe Sepsis Model [dagger]. | Role of Pellino-1 in Inflammation and Cardioprotection following Severe Sepsis: A Novel Mechanism in a Murine Severe Sepsis Model (†).
Thirunavukkarasu M, Swaminathan S, Kemerley A, Pradeep SR, Lim ST, Accorsi D, Wilson R, Campbell J, Saad I, Yee SP, Palesty JA, McFadden DW, Maulik N., Free PMC Article | 06/14/2023 |
| Pellino-1 promotes intrinsic activation of skin-resident IL-17A-producing T cells in psoriasis. | Pellino-1 promotes intrinsic activation of skin-resident IL-17A-producing T cells in psoriasis.
Kim SH, Oh J, Roh WS, Park J, Chung KB, Lee GH, Lee YS, Kim JH, Lee HK, Lee H, Park CO, Kim DY, Lee MG, Kim TG. | 05/11/2023 |
| Regulatory T Cells Overexpressing Peli1 Show Better Efficacy in Repairing Ovarian Endocrine Function in Autoimmune Premature Ovarian Insufficiency. | Regulatory T Cells Overexpressing Peli1 Show Better Efficacy in Repairing Ovarian Endocrine Function in Autoimmune Premature Ovarian Insufficiency.
Wang Y, Zhuo A, Yang Y, Wang Q, Xie J, Ma W, Chen Y, Gao M, Tang L, Fu X. | 04/14/2023 |
| Pellino1 Restricts Herpes Simplex Virus Infections in the Epidermis and Dissemination to Sebaceous Glands. | Pellino1 Restricts Herpes Simplex Virus Infections in the Epidermis and Dissemination to Sebaceous Glands.
Cai KQ, Shellhamer C, Akiyama T, Jensen LE., Free PMC Article | 03/27/2023 |
| Peli1 deletion in macrophages attenuates myocardial ischemia/reperfusion injury by suppressing M1 polarization. | Peli1 deletion in macrophages attenuates myocardial ischemia/reperfusion injury by suppressing M1 polarization.
Chen H, Hou Y, Zhai Y, Yang J, Que L, Liu J, Lu L, Ha T, Li C, Xu Y, Li J, Li Y. | 02/27/2023 |
| Peli1 contributes to myocardial ischemia/reperfusion injury by impairing autophagy flux via its E3 ligase mediated ubiquitination of P62. | Peli1 contributes to myocardial ischemia/reperfusion injury by impairing autophagy flux via its E3 ligase mediated ubiquitination of P62.
Yang J, Tong T, Zhu C, Zhou M, Jiang Y, Chen H, Que L, Liu L, Zhu G, Ha T, Chen Q, Li C, Xu Y, Li J, Li Y. | 12/3/2022 |
| The E3 Ubiquitin Ligase Peli1 Deficiency Promotes Atherosclerosis Progression. | The E3 Ubiquitin Ligase Peli1 Deficiency Promotes Atherosclerosis Progression.
Burger F, Baptista D, Roth A, Brandt KJ, Miteva K., Free PMC Article | 07/16/2022 |
| miR-590-5p Overexpression Alleviates beta-Amyloid-Induced Neuron Damage via Targeting Pellino-1. | miR-590-5p Overexpression Alleviates β-Amyloid-Induced Neuron Damage via Targeting Pellino-1.
Shang L, Peng T, Chen X, Yan Z, Wang J, Gao X, Chang C., Free PMC Article | 04/16/2022 |
| Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination. | Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination.
Zhang L, Ko CJ, Li Y, Jie Z, Zhu L, Zhou X, Xie X, Gao T, Liu T, Cheng X, Sun SC. | 02/12/2022 |
| The ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity. | The ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity.
Huang X, Hao S, Liu J, Huang Y, Liu M, Xiao C, Wang Y, Pei S, Yu T, Xu J, Wang H, Dai D, Su X, Xiao Y., Free PMC Article | 01/1/2022 |
| Transforming Growth Factor-beta1 Promotes M1 Alveolar Macrophage Polarization in Acute Lung Injury by Up-Regulating DNMT1 to Mediate the microRNA-124/PELI1/IRF5 Axis. | Transforming Growth Factor-β1 Promotes M1 Alveolar Macrophage Polarization in Acute Lung Injury by Up-Regulating DNMT1 to Mediate the microRNA-124/PELI1/IRF5 Axis.
Wang Y, Wang X, Zhang H, Han B, Ye Y, Zhang M, Wang Y, Xue J, Wang C., Free PMC Article | 10/23/2021 |
| Pellino1 promotes chronic inflammatory skin disease via keratinocyte hyperproliferation and induction of the T helper 17 response. | Pellino1 promotes chronic inflammatory skin disease via keratinocyte hyperproliferation and induction of the T helper 17 response.
Kim S, Lee SY, Bae S, Lee JK, Hwang K, Go H, Lee CW., Free PMC Article | 10/2/2021 |
| Deletion of newly described pro-survival molecule Pellino-1 increases oxidative stress, downregulates cIAP2/NF-kappaB cell survival pathway, reduces angiogenic response, and thereby aggravates tissue function in mouse ischemic models. | Deletion of newly described pro-survival molecule Pellino-1 increases oxidative stress, downregulates cIAP2/NF-κB cell survival pathway, reduces angiogenic response, and thereby aggravates tissue function in mouse ischemic models.
Selvaraju V, Thirunavukkarasu M, Joshi M, Oriowo B, Shaikh IA, Rishi MT, Tapias L, Coca-Soliz V, Saad I, Campbell J, Pradeep SR, Swaminathan S, Yee SP, McFadden DW, Alexander Palesty J, Maulik N. | 07/10/2021 |
| Redox DAPK1 destabilizes Pellino1 to govern inflammation-coupling tubular damage during septic AKI. | Redox DAPK1 destabilizes Pellino1 to govern inflammation-coupling tubular damage during septic AKI.
Hu BC, Wu GH, Shao ZQ, Zheng Y, Liu JQ, Zhang R, Hong J, Yang XH, Sun RH, Mo SJ., Free PMC Article | 06/5/2021 |
| The E3 ubiquitin ligase Peli1 regulates the metabolic actions of mTORC1 to suppress antitumor T cell responses. | The E3 ubiquitin ligase Peli1 regulates the metabolic actions of mTORC1 to suppress antitumor T cell responses.
Ko CJ, Zhang L, Jie Z, Zhu L, Zhou X, Xie X, Gao T, Yang JY, Cheng X, Sun SC., Free PMC Article | 04/24/2021 |
| Inhibition of Glycolysis in Pathogenic TH17 Cells through Targeting a miR -21-Peli1-c-Rel Pathway Prevents Autoimmunity. | Inhibition of Glycolysis in Pathogenic T(H)17 Cells through Targeting a miR -21-Peli1-c-Rel Pathway Prevents Autoimmunity.
Qiu R, Yu X, Wang L, Han Z, Yao C, Cui Y, Hou G, Dai D, Jin W, Shen N. | 02/13/2021 |
| Peli1 impairs microglial Abeta phagocytosis through promoting C/EBPbeta degradation. | Peli1 impairs microglial Aβ phagocytosis through promoting C/EBPβ degradation.
Xu J, Yu T, Pietronigro EC, Yuan J, Arioli J, Pei Y, Luo X, Ye J, Constantin G, Mao C, Xiao Y., Free PMC Article | 12/12/2020 |
| Pellino1 regulates neuropathic pain as well as microglial activation through the regulation of MAPK/NF-kappaB signaling in the spinal cord. | Pellino1 regulates neuropathic pain as well as microglial activation through the regulation of MAPK/NF-κB signaling in the spinal cord.
Wang L, Yin C, Liu T, Abdul M, Zhou Y, Cao JL, Lu C., Free PMC Article | 12/12/2020 |
| Peli1 controls the survival of dopaminergic neurons through modulating microglia-mediated neuroinflammation. | Peli1 controls the survival of dopaminergic neurons through modulating microglia-mediated neuroinflammation.
Dai D, Yuan J, Wang Y, Xu J, Mao C, Xiao Y., Free PMC Article | 10/24/2020 |
| Pellino-1 Regulates Immune Responses to Haemophilus influenzae in Models of Inflammatory Lung Disease. | Pellino-1 Regulates Immune Responses to Haemophilus influenzae in Models of Inflammatory Lung Disease.
Hughes BM, Burton CS, Reese A, Jabeen MF, Wright C, Willis J, Khoshaein N, Marsh EK, Peachell P, Sun SC, Dockrell DH, Marriott HM, Sabroe I, Condliffe AM, Prince LR., Free PMC Article | 10/3/2020 |
| Peli1 signaling blockade attenuates congenital zika syndrome. | Peli1 signaling blockade attenuates congenital zika syndrome.
Luo H, Li G, Wang B, Tian B, Gao J, Zou J, Shi S, Zhu S, Peng BH, Adam A, Martinez A, Hein K, Winkelmann ER, Mahmoud Y, Zhou X, Shan C, Rossi S, Weaver S, Barrett ADT, Sun SC, Zhang W, Shi PY, Wu P, Wang T., Free PMC Article | 08/15/2020 |
| Heat shock protein 90 (Hsp90) as a potential binding partner for Peli1, and the Ring domain of Peli1 directly bound with Hsp90 to enhance IRE1alpha phosphorylation. Blocking Peli1 in endothelial cells may protect against diabetes-induced cardiac microvascular injury by restraining ER stress. | Peli1 induction impairs cardiac microvascular endothelium through Hsp90 dissociation from IRE1α.
Zhao Q, Yang J, Chen H, Li J, Que L, Zhu G, Liu L, Ha T, Chen Q, Li C, Xu Y, Li Y. | 05/16/2020 |
| the present study reveals a novel signaling pathway, the miR-142a-3p/miR-155-5p/E3 ubiquitin-protein ligase pellino homolog 1 axis in Methamphetamine-mediated neuroinflammation | MiR-142a-3p and miR-155-5p reduce methamphetamine-induced inflammation: Role of the target protein Peli1.
Yu G, Song Y, Xie C, Tao L, Wan F, Jiang L, Wang J, Tang J. | 04/18/2020 |