| Staufen1 Represses the FOXA1-Regulated Transcriptome by Destabilizing FOXA1 mRNA in Colorectal Cancer Cells. | Staufen1 Represses the FOXA1-Regulated Transcriptome by Destabilizing FOXA1 mRNA in Colorectal Cancer Cells.
Pasterczyk KR, Li XL, Singh R, Zibitt MS, Hartford CCR, Pongor L, Jenkins LM, Hu Y, Zhao PX, Muys BR, Kumar S, Roper N, Aladjem MI, Pommier Y, Grammatikakis I, Lal A., | 03/20/2024 |
| A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation. | A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.
Gonzalez Quesada Y, DesGroseillers L., Free PMC Article | 10/22/2022 |
| Phosphomimicry on STAU1 Serine 20 Impairs STAU1 Posttranscriptional Functions and Induces Apoptosis in Human Transformed Cells. | Phosphomimicry on STAU1 Serine 20 Impairs STAU1 Posttranscriptional Functions and Induces Apoptosis in Human Transformed Cells.
Gonzalez Quesada Y, Bonnet-Magnaval F, DesGroseillers L., Free PMC Article | 07/23/2022 |
| PART1 destabilized by NOVA2 regulates blood-brain barrier permeability in endothelial cells via STAU1-mediated mRNA degradation. | PART1 destabilized by NOVA2 regulates blood-brain barrier permeability in endothelial cells via STAU1-mediated mRNA degradation.
Ning H, Zhang T, Zhou X, Liu L, Shang C, Qi R, Ma T. | 02/12/2022 |
| Function of Host Protein Staufen1 in Rabies Virus Replication. | Function of Host Protein Staufen1 in Rabies Virus Replication.
Liu G, Chen C, Xu R, Yang M, Han Q, Wang B, Song Y, Xia X, Zhang J., Free PMC Article | 02/5/2022 |
| High Level of Staufen1 Expression Confers Longer Recurrence Free Survival to Non-Small Cell Lung Cancer Patients by Promoting THBS1 mRNA Degradation. | High Level of Staufen1 Expression Confers Longer Recurrence Free Survival to Non-Small Cell Lung Cancer Patients by Promoting THBS1 mRNA Degradation.
Bonnet-Magnaval F, Diallo LH, Brunchault V, Laugero N, Morfoisse F, David F, Roussel E, Nougue M, Zamora A, Marchaud E, Tatin F, Prats AC, Garmy-Susini B, DesGroseillers L, Lacazette E., Free PMC Article | 02/5/2022 |
| Differential regulation of autophagy by STAU1 in alveolar rhabdomyosarcoma and non-transformed skeletal muscle cells. | Differential regulation of autophagy by STAU1 in alveolar rhabdomyosarcoma and non-transformed skeletal muscle cells.
Almasi S, Crawford Parks TE, Ravel-Chapuis A, MacKenzie A, Côté J, Cowan KN, Jasmin BJ. | 01/15/2022 |
| LncCCLM inhibits lymphatic metastasis of cervical cancer by promoting STAU1-mediated IGF-1 mRNA degradation. | LncCCLM inhibits lymphatic metastasis of cervical cancer by promoting STAU1-mediated IGF-1 mRNA degradation.
Chen C, Shen N, Chen Y, Jiang P, Sun W, Wang Q, Wang Z, Jiang Y, Cheng W, Fu S, Wang S. | 01/8/2022 |
| NF-kappaB-activated SPRY4-IT1 promotes cancer cell metastasis by downregulating TCEB1 mRNA via Staufen1-mediated mRNA decay. | NF-κB-activated SPRY4-IT1 promotes cancer cell metastasis by downregulating TCEB1 mRNA via Staufen1-mediated mRNA decay.
Zhao L, Jiang L, Zhang M, Zhang Q, Guan Q, Li Y, He M, Zhang J, Wei M., Free PMC Article | 01/8/2022 |
| The multifunctional RNA-binding protein Staufen1: an emerging regulator of oncogenesis through its various roles in key cellular events. | The multifunctional RNA-binding protein Staufen1: an emerging regulator of oncogenesis through its various roles in key cellular events.
Almasi S, Jasmin BJ., Free PMC Article | 12/11/2021 |
| Noncanonical immune response to the inhibition of DNA methylation by Staufen1 via stabilization of endogenous retrovirus RNAs. | Noncanonical immune response to the inhibition of DNA methylation by Staufen1 via stabilization of endogenous retrovirus RNAs.
Ku Y, Park JH, Cho R, Lee Y, Park HM, Kim M, Hur K, Byun SY, Liu J, Lee YS, Shum D, Shin DY, Koh Y, Cho JY, Yoon SS, Hong J, Kim Y., Free PMC Article | 10/23/2021 |
| IGF2BP2 stabilized FBXL19-AS1 regulates the blood-tumour barrier permeability by negatively regulating ZNF765 by STAU1-mediated mRNA decay. | IGF2BP2 stabilized FBXL19-AS1 regulates the blood-tumour barrier permeability by negatively regulating ZNF765 by STAU1-mediated mRNA decay.
Liu X, Wu P, Su R, Xue Y, Yang C, Wang D, Ruan X, Zheng J, Yang Y, Li Z, Liu Y., Free PMC Article | 09/18/2021 |
| Overexpression of Staufen1 in DM1 mouse skeletal muscle exacerbates dystrophic and atrophic features. | Overexpression of Staufen1 in DM1 mouse skeletal muscle exacerbates dystrophic and atrophic features.
Crawford Parks TE, Marcellus KA, Péladeau C, Jasmin BJ, Ravel-Chapuis A., Free PMC Article | 08/21/2021 |
| Staufen1 in Human Neurodegeneration. | Staufen1 in Human Neurodegeneration.
Paul S, Dansithong W, Figueroa KP, Gandelman M, Scoles DR, Pulst SM., Free PMC Article | 08/7/2021 |
| STAU1 selectively regulates the expression of inflammatory and immune response genes and alternative splicing of the nerve growth factor receptor signaling pathway. | STAU1 selectively regulates the expression of inflammatory and immune response genes and alternative splicing of the nerve growth factor receptor signaling pathway.
Zhong Y, Hu Z, Wu J, Dai F, Lee F, Xu Y., Free PMC Article | 07/10/2021 |
| Distinct roles for the RNA-binding protein Staufen1 in prostate cancer. | Distinct roles for the RNA-binding protein Staufen1 in prostate cancer.
Marcellus KA, Crawford Parks TE, Almasi S, Jasmin BJ., Free PMC Article | 05/15/2021 |
| PABPC1-induced stabilization of BDNF-AS inhibits malignant progression of glioblastoma cells through STAU1-mediated decay. | PABPC1-induced stabilization of BDNF-AS inhibits malignant progression of glioblastoma cells through STAU1-mediated decay.
Su R, Ma J, Zheng J, Liu X, Liu Y, Ruan X, Shen S, Yang C, Wang D, Cai H, Li Z, Xue Y., Free PMC Article | 02/20/2021 |
| 3'READS + RIP defines differential Staufen1 binding to alternative 3'UTR isoforms and reveals structures and sequence motifs influencing binding and polysome association. | 3'READS + RIP defines differential Staufen1 binding to alternative 3'UTR isoforms and reveals structures and sequence motifs influencing binding and polysome association.
Zheng D, Cho H, Wang W, Rambout X, Tian B, Maquat LE., Free PMC Article | 01/23/2021 |
| Staufen1 is Essential for Cell-Cycle Transitions and Cell Proliferation Via the Control of E2F1 Expression. | Staufen1 is Essential for Cell-Cycle Transitions and Cell Proliferation Via the Control of E2F1 Expression.
Ghram M, Bonnet-Magnaval F, Hotea DI, Doran B, Ly S, DesGroseillers L. | 01/2/2021 |
| we present the first solution structure models for full-length hStaufen1(55), showing that its domains are arranged as beads-on-a-string connected by flexible linkers. In analogy with other nucleic acid-binding proteins, this could underpin Stau1 functional plasticity. | A multipronged approach to understanding the form and function of hStaufen protein.
Visentin S, Cannone G, Doutch J, Harris G, Gleghorn ML, Clifton L, Smith BO, Spagnolo L., Free PMC Article | 06/20/2020 |
| Mutants disrupting minor groove recognition of ARF1 SBS affect in vitro binding and reduce STAU1-mediated mRNA decay (SMD) in vivo. Our data thus reveal how STAU1 recognizes minor groove features in dsRNA relevant for target selection | Staufen1 reads out structure and sequence features in ARF1 dsRNA for target recognition.
Yadav DK, Zigáčková D, Zlobina M, Klumpler T, Beaumont C, Kubíčková M, Vaňáčová Š, Lukavsky PJ., Free PMC Article | 03/21/2020 |
| our data highlight the functional importance of STAU1 and UPF1 in the course of the replacement of the cap-binding complex (CBC) by eIF4E, adding a previously unappreciated layer of post-transcriptional gene regulation. | Staufen1 and UPF1 exert opposite actions on the replacement of the nuclear cap-binding complex by eIF4E at the 5' end of mRNAs.
Jeong K, Ryu I, Park J, Hwang HJ, Ha H, Park Y, Oh ST, Kim YK., Free PMC Article | 12/14/2019 |
| The findings illustrate that lipopolysaccharide participates in Hirschsprung's disease through the ADAR2-miR-142-STAU1 axis. | Lipopolysaccharide enhances ADAR2 which drives Hirschsprung's disease by impairing miR-142-3p biogenesis.
Peng L, Zhang H, Su Y, Shen Q, Du C, Xie H, Li H, Yan J, Shen Z, Jiang W, Xia Y, Xu X, Tang W., Free PMC Article | 11/2/2019 |
| The results revealed the collaboration of two RNA-binding proteins, STAU1 and Lin28B, as a regulatory mechanism in neuronal differentiation. | Lin28B and miR-142-3p regulate neuronal differentiation by modulating Staufen1 expression.
Oh Y, Park J, Kim JI, Chang MY, Lee SH, Cho YH, Hwang J., Free PMC Article | 08/24/2019 |
| HIV-1 requires Staufen1 to dissociate stress granules and to produce infectious viral particles. | HIV-1 requires Staufen1 to dissociate stress granules and to produce infectious viral particles.
Rao S, Hassine S, Monette A, Amorim R, DesGroseillers L, Mouland AJ., Free PMC Article | 06/15/2019 |