| The c.11G>T mutation of the TAF4B gene may be associated with NOA in a Chinese population. | Analysis of TATA-box binding protein associated factor 4b gene mutations in a Chinese population with nonobstructive azoospermia.
Xi Q, Zhang H, Zhang X, Jiang Y, Wang R, Liu R, Zhang H., Free PMC Article | 06/27/2020 |
| Nonobstructive Azoospermia variants included MTRR c.537T>C (rs161870), odds ratios (OR), 3.686, 95% confidence interval (CI), 1.228-11.066; MTRR, c.1049A>G (rs162036), OR, 3.686, 95% CI, 1.228-11.066; PIWIL1, c.1580G>A (rs1106042), OR, 4.737, 95% CI, 1.314-17.072; TAF4B, c.1815T>C (rs1677016), OR, 3.599, 95% CI, 1.255-10.327; and SOX10 c.927T>C (rs139884), OR, 3.192, 95% CI, 1.220-8.353. | Targeted Next-Generation Sequencing Identifies Novel Sequence Variations of Genes Associated with Nonobstructive Azoospermia in the Han Population of Northeast China.
Liu X, Xi Q, Li L, Wang Q, Jiang Y, Zhang H, Liu R, Wang R., Free PMC Article | 02/22/2020 |
| The methionine synthase reductase (MTRR), TAF4B protein, PIWI protein (PIWIL1) four single nucleotide polymorphisms (SNPs) are not shown to be significantly related with non-obstructive azoospermia (NOA). | Association Study Between MTRR, TAF4B, PIWIL1 Variants and Non-Obstructive Azoospermia in Northeast Chinese Han Population.
Yang X, Zhang H, Jiang Y, Zhang H, Hu X, Zhu D, Geng D, Liu R. | 09/14/2019 |
| The existence of a highly conserved TAF4b-dependent gene regulatory network. | TAF4b Regulates Oocyte-Specific Genes Essential for Meiosis.
Grive KJ, Gustafson EA, Seymour KA, Baddoo M, Schorl C, Golnoski K, Rajkovic A, Brodsky AS, Freiman RN., Free PMC Article | 03/18/2017 |
| Two candidate loci in each family and homozygous truncating mutations p.R611X in TAF4B in family 1 and p.K507Sfs*3 in ZMYND15 in family 2, were identified. | Truncating mutations in TAF4B and ZMYND15 causing recessive azoospermia.
Ayhan Ö, Balkan M, Guven A, Hazan R, Atar M, Tok A, Tolun A. | 11/22/2014 |
| We show evidence for the first time of an interdependence of TAF4b and AP-1 family members in cell type-specific promoter recognition and initiation of transcription in the context of cancer progression and EMT. | TAF4b and Jun/activating protein-1 collaborate to regulate the expression of integrin alpha6 and cancer cell migration properties.
Kalogeropoulou M, Voulgari A, Kostourou V, Sandaltzopoulos R, Dikstein R, Davidson I, Tora L, Pintzas A. | 07/19/2010 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | Genome-wide association study in premature ovarian failure patients suggests ADAMTS19 as a possible candidate gene.
Knauff EA, Franke L, van Es MA, van den Berg LH, van der Schouw YT, Laven JS, Lambalk CB, Hoek A, Goverde AJ, Christin-Maitre S, Hsueh AJ, Wijmenga C, Fauser BC, Dutch POF Consortium. | 12/2/2009 |
| Findings suggest that DNA binding by TAF4/4b-TAF12 facilitates the association of TFIID with the core promoter of a subset of genes. | TAF4/4b x TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes.
Gazit K, Moshonov S, Elfakess R, Sharon M, Mengus G, Davidson I, Dikstein R., Free PMC Article | 01/21/2010 |
| Expression of the TAF4b gene is induced by MYC through a non-canonical, but not canonical, E-box which contributes to its specific response to MYC. | Expression of the TAF4b gene is induced by MYC through a non-canonical, but not canonical, E-box which contributes to its specific response to MYC.
Teye K, Okamoto K, Tanaka Y, Umata T, Ohnuma M, Moroi M, Kimura H, Tsuneoka M. | 01/21/2010 |
| TAF4b incorporation into TFIID induces an open conformation at the lobe involved in TFIIA & putative activator interactions, correlating with differential activator-dependent transcription & promoter recognition by 4b/4-IID. | Structural changes in TAF4b-TFIID correlate with promoter selectivity.
Liu WL, Coleman RA, Grob P, King DS, Florens L, Washburn MP, Geles KG, Yang JL, Ramey V, Nogales E, Tjian R., Free PMC Article | 01/21/2010 |
| histone fold domain mediated interaction enhances the DNA binding activity of each of the TAF6-TAF9 and TAF4b-TAF12 pairs and of a histone-like octamer complex composed of the four TAFs | Core promoter binding by histone-like TAF complexes.
Shao H, Revach M, Moshonov S, Tzuman Y, Gazit K, Albeck S, Unger T, Dikstein R., Free PMC Article | 01/21/2010 |
| work suggests that pre-mRNA processing and post-translational modification represent two important regulatory steps for the gonad-specific functions of human TAF(II)105 | Cyclic AMP-dependent modification of gonad-selective TAF(II)105 in a human ovarian granulosa cell line.
Wu Y, Lu Y, Hu Y, Li R. | 01/21/2010 |