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    ZEB1 zinc finger E-box binding homeobox 1 [ Homo sapiens (human) ]

    Gene ID: 6935, updated on 17-Oct-2021

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    ZEB1 induces non-small cell lung cancer development by targeting microRNA-320a to increase the expression of RAD51AP1.

    ZEB1 induces non-small cell lung cancer development by targeting microRNA-320a to increase the expression of RAD51AP1.
    Wang H, Dong H, Qiao L, Wu Y, Wu B, Jin X.

    10/16/2021
    DNAJB9 suppresses the metastasis of triple-negative breast cancer by promoting FBXO45-mediated degradation of ZEB1.

    DNAJB9 suppresses the metastasis of triple-negative breast cancer by promoting FBXO45-mediated degradation of ZEB1.
    Kim HY, Kim YM, Hong S., Free PMC Article

    10/16/2021
    Circ-HMGA2 (hsa_circ_0027446) promotes the metastasis and epithelial-mesenchymal transition of lung adenocarcinoma cells through the miR-1236-3p/ZEB1 axis.

    Circ-HMGA2 (hsa_circ_0027446) promotes the metastasis and epithelial-mesenchymal transition of lung adenocarcinoma cells through the miR-1236-3p/ZEB1 axis.
    Yu Z, Zhu X, Li Y, Liang M, Liu M, Liu Z, Qin L, Wu X, Du K, Liu L, Wang Y, Zheng Y., Free PMC Article

    10/16/2021
    CDK4/6 inhibition blocks cancer metastasis through a USP51-ZEB1-dependent deubiquitination mechanism.

    CDK4/6 inhibition blocks cancer metastasis through a USP51-ZEB1-dependent deubiquitination mechanism.
    Zhang Z, Li J, Ou Y, Yang G, Deng K, Wang Q, Wang Z, Wang W, Zhang Q, Wang H, Sun W, Sun P, Yang S., Free PMC Article

    10/16/2021
    Nerve growth factor receptor increases the tumor growth and metastatic potential of triple-negative breast cancer cells.

    Nerve growth factor receptor increases the tumor growth and metastatic potential of triple-negative breast cancer cells.
    Wu R, Li K, Yuan M, Luo KQ.

    10/16/2021
    ZEB1 serves as an oncogene in acute myeloid leukaemia via regulating the PTEN/PI3K/AKT signalling pathway by combining with P53.

    ZEB1 serves as an oncogene in acute myeloid leukaemia via regulating the PTEN/PI3K/AKT signalling pathway by combining with P53.
    Li L, Feng Y, Hu S, Du Y, Xu X, Zhang M, Peng X, Chen F., Free PMC Article

    10/2/2021
    ZEB1-induced LINC01559 expedites cell proliferation, migration and EMT process in gastric cancer through recruiting IGF2BP2 to stabilize ZEB1 expression.

    ZEB1-induced LINC01559 expedites cell proliferation, migration and EMT process in gastric cancer through recruiting IGF2BP2 to stabilize ZEB1 expression.
    Shen H, Zhu H, Chen Y, Shen Z, Qiu W, Qian C, Zhang J., Free PMC Article

    09/25/2021
    The novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway.

    The novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway.
    Xiang T, Yuan C, Guo X, Wang H, Cai Q, Xiang Y, Luo W, Liu G., Free PMC Article

    09/18/2021
    Zinc-Dependent Regulation of ZEB1 and YAP1 Coactivation Promotes Epithelial-Mesenchymal Transition Plasticity and Metastasis in Pancreatic Cancer.

    Zinc-Dependent Regulation of ZEB1 and YAP1 Coactivation Promotes Epithelial-Mesenchymal Transition Plasticity and Metastasis in Pancreatic Cancer.
    Liu M, Zhang Y, Yang J, Zhan H, Zhou Z, Jiang Y, Shi X, Fan X, Zhang J, Luo W, Fung KA, Xu C, Bronze MS, Houchen CW, Li M.,

    09/4/2021
    Non-Penetrance for Ocular Phenotype in Two Individuals Carrying Heterozygous Loss-of-Function ZEB1 Alleles.

    Non-Penetrance for Ocular Phenotype in Two Individuals Carrying Heterozygous Loss-of-Function <i>ZEB1</i> Alleles.
    Dudakova L, Stranecky V, Piherova L, Palecek T, Pontikos N, Kmoch S, Skalicka P, Vaneckova M, Davidson AE, Liskova P., Free PMC Article

    08/28/2021
    ZEB1 directly inhibits GPX4 transcription contributing to ROS accumulation in breast cancer cells.

    ZEB1 directly inhibits GPX4 transcription contributing to ROS accumulation in breast cancer cells.
    Han X, Duan X, Liu Z, Long Y, Liu C, Zhou J, Li N, Qin J, Wang Y.

    08/28/2021
    Zeb1 for RCP-induced oral cancer cell invasion and its suppression by resveratrol.

    Zeb1 for RCP-induced oral cancer cell invasion and its suppression by resveratrol.
    Kim JY, Cho KH, Jeong BY, Park CG, Lee HY., Free PMC Article

    08/14/2021
    miR-144-3p inhibited the growth, metastasis and epithelial-mesenchymal transition of colorectal adenocarcinoma by targeting ZEB1/2.

    miR-144-3p inhibited the growth, metastasis and epithelial-mesenchymal transition of colorectal adenocarcinoma by targeting ZEB1/2.
    Li T, Tang C, Huang Z, Yang L, Dai H, Tang B, Xiao B, Li J, Lei X., Free PMC Article

    07/31/2021
    ZEB1 enhances Warburg effect to facilitate tumorigenesis and metastasis of HCC by transcriptionally activating PFKM.

    ZEB1 enhances Warburg effect to facilitate tumorigenesis and metastasis of HCC by transcriptionally activating PFKM.
    Zhou Y, Lin F, Wan T, Chen A, Wang H, Jiang B, Zhao W, Liao S, Wang S, Li G, Xu Z, Wang J, Zhang J, Ma H, Lin D, Li Q., Free PMC Article

    07/31/2021
    FOXE1 regulates migration and invasion in thyroid cancer cells and targets ZEB1.

    FOXE1 regulates migration and invasion in thyroid cancer cells and targets ZEB1.
    Morillo-Bernal J, Fernández LP, Santisteban P., Free PMC Article

    07/31/2021
    miR-34a inhibits melanoma growth by targeting ZEB1.

    miR-34a inhibits melanoma growth by targeting ZEB1.
    Xu Y, Guo B, Liu X, Tao K., Free PMC Article

    07/24/2021
    Proteomic Analysis of Zeb1 Interactome in Breast Carcinoma Cells.

    Proteomic Analysis of Zeb1 Interactome in Breast Carcinoma Cells.
    Parfenyev SE, Shabelnikov SV, Pozdnyakov DY, Gnedina OO, Adonin LS, Barlev NA, Mittenberg AG., Free PMC Article

    07/24/2021
    Tumor suppressor DCAF15 inhibits epithelial-mesenchymal transition by targeting ZEB1 for proteasomal degradation in hepatocellular carcinoma.

    Tumor suppressor DCAF15 inhibits epithelial-mesenchymal transition by targeting ZEB1 for proteasomal degradation in hepatocellular carcinoma.
    Dong X, Han Y, Zhang E, Wang Y, Zhang P, Wang C, Zhong L, Li Q., Free PMC Article

    07/24/2021
    circFAT1(e2) Promotes Papillary Thyroid Cancer Proliferation, Migration, and Invasion via the miRNA-873/ZEB1 Axis.

    circFAT1(e2) Promotes Papillary Thyroid Cancer Proliferation, Migration, and Invasion via the miRNA-873/ZEB1 Axis.
    Liu J, Li H, Wei C, Ding J, Lu J, Pan G, Mao A., Free PMC Article

    07/17/2021
    ZEB1: New advances in fibrosis and cancer.

    ZEB1: New advances in fibrosis and cancer.
    Cheng L, Zhou MY, Gu YJ, Chen L, Wang Y.

    07/17/2021
    NORAD regulates proliferation and apoptosis in cardiomyocytes under high-glucose treatment through miRNA-150-5p/ZEB1 axis.

    NORAD regulates proliferation and apoptosis in cardiomyocytes under high-glucose treatment through miRNA-150-5p/ZEB1 axis.
    Han Y, Tian H, Gao X.

    07/3/2021
    Circular RNA hsa_circ_0001178 facilitates the invasion and metastasis of colorectal cancer through upregulating ZEB1 via sponging multiple miRNAs.

    Circular RNA hsa_circ_0001178 facilitates the invasion and metastasis of colorectal cancer through upregulating ZEB1 via sponging multiple miRNAs.
    Ren C, Zhang Z, Wang S, Zhu W, Zheng P, Wang W.

    06/26/2021
    Oncogenic functions of the EMT-related transcription factor ZEB1 in breast cancer.

    Oncogenic functions of the EMT-related transcription factor ZEB1 in breast cancer.
    Wu HT, Zhong HT, Li GW, Shen JX, Ye QQ, Zhang ML, Liu J., Free PMC Article

    06/19/2021
    Knockdown of the Long Noncoding RNA LUCAT1 Inhibits High-Glucose-Induced Epithelial-Mesenchymal Transition through the miR-199a-5p-ZEB1 Axis in Human Renal Tubular Epithelial Cells.

    Knockdown of the Long Noncoding RNA LUCAT1 Inhibits High-Glucose-Induced Epithelial-Mesenchymal Transition through the miR-199a-5p-ZEB1 Axis in Human Renal Tubular Epithelial Cells.
    Zhang LC, Wei ZB, Tang SF., Free PMC Article

    05/29/2021
    LncRNA TUG1 facilitates proliferation, invasion and stemness of ovarian cancer cell via miR-186-5p/ZEB1 axis.

    LncRNA TUG1 facilitates proliferation, invasion and stemness of ovarian cancer cell via miR-186-5p/ZEB1 axis.
    Zhan FL, Chen CF, Yao MZ.

    05/29/2021
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