| Characterization of a possible founder synonymous variant in TECTA in multiple individuals with autosomal recessive hearing loss. | Characterization of a possible founder synonymous variant in TECTA in multiple individuals with autosomal recessive hearing loss.
Chen R, Diaz-Miranda MA, Aref-Eshghi E, Hartman TR, Griffith C, Morrison JL, Wheeler PG, Torti E, Richard G, Kenna M, Dechene ET, Spinner NB, Bai R, Conlin LK, Krantz ID, Amr SS, Luo M. | 12/17/2022 |
| Next-Generation Sequencing Identifies Pathogenic Variants in HGF, POU3F4, TECTA, and MYO7A in Consanguineous Pakistani Deaf Families. | Next-Generation Sequencing Identifies Pathogenic Variants in HGF, POU3F4, TECTA, and MYO7A in Consanguineous Pakistani Deaf Families.
Mei X, Zhou Y, Amjad M, Yang W, Zhu R, Asif M, Hussain HMJ, Yang T, Iqbal F, Hu H., Free PMC Article | 12/11/2021 |
| A comparative analysis of genetic hearing loss phenotypes in European/American and Japanese populations. | A comparative analysis of genetic hearing loss phenotypes in European/American and Japanese populations.
Walls WD, Moteki H, Thomas TR, Nishio SY, Yoshimura H, Iwasa Y, Frees KL, Nishimura CJ, Azaiez H, Booth KT, Marini RJ, Kolbe DL, Weaver AM, Schaefer AM, Wang K, Braun TA, Usami SI, Barr-Gillespie PG, Richardson GP, Smith RJ, Casavant TL., Free PMC Article | 09/26/2020 |
| homozygous c.1893C>A mutation of the TECTA gene probably underlies the proband's hearing loss which conformed to an autosomal recessive inheritance | [Diagnosis and reproductive guidance for a couple carrying a novel c.1893C>T mutation of the TECTA gene].
Zhou C, Li S, Song Q, Liu X, Miao Z. | 08/31/2019 |
| TECTA mutations were identified in 6.0% of mid-frequency sensorineural hearing loss cases; these mutations were more frequent in patients with shallow U-shaped audiograms than those with U-shaped audiograms, and in families which have the family histories compatible with autosomal dominant than those with the family histories compatible with sporadic or autosomal recessive. | Prevalence of TECTA mutation in patients with mid-frequency sensorineural hearing loss.
Yamamoto N, Mutai H, Namba K, Morita N, Masuda S, Nishi Y, Nakano A, Masuda S, Fujioka M, Kaga K, Ogawa K, Matsunaga T., Free PMC Article | 07/21/2018 |
| Up to now, merely 7 loci have been linked to mid-frequency hearing loss. Only four genetic mid-frequency deafness genes, namely, DFNA10 (EYA4), DFNA8/12 (TECTA), DFNA13 (COL11A2), DFNA44 (CCDC50), have been reported to date. [review] | Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness.
Xia W, Liu F, Ma D. | 04/22/2017 |
| A novel homozygous variant (c.734G > A) was found in exon 5 of the TECTA gene in one family leading to a nonsense mutation causing autosomal recessive nonsyndromic hearing loss. | A novel TECTA mutation causes ARNSHL.
Asgharzade S, Tabatabaiefar MA, Modarressi MH, Ghahremani MH, Reiisi S, Tahmasebi P, Abdollahnejad F, Chaleshtori MH. | 03/25/2017 |
| To our knowledge, this is the first reported TECTA mutation leading to the DFNB21 form of hearing impairment among Maghrebian individuals suffering from congenital hearing impairment | A novel biallelic splice site mutation of TECTA causes moderate to severe hearing impairment in an Algerian family.
Behlouli A, Bonnet C, Abdi S, Hasbellaoui M, Boudjenah F, Hardelin JP, Louha M, Makrelouf M, Ammar-Khodja F, Zenati A, Petit C. | 03/18/2017 |
| the present report suggest that the association of RWDD3 and TECTA with paclitaxel-induced peripheral neuropathy may have been a false positive signal | RWDD3 and TECTA variants not linked to paclitaxel induced peripheral neuropathy in North American trial Alliance N08C1.
Kulkarni AA, Boora G, Kanwar R, Ruddy KJ, Banck MS, Le-Lindqwister N, Therneau TM, Loprinzi CL, Beutler AS., Free PMC Article | 06/28/2016 |
| Here we confirm a known genotype-phenotype correlation for the ZP domain and propose a hypothetical genotype-phenotype correlation which relates mutations in vWFD3-D4 to stable high-frequency NSHL in Koreans. | Novel TECTA mutations identified in stable sensorineural hearing loss and their clinical implications.
Kim AR, Chang MY, Koo JW, Oh SH, Choi BY. | 09/12/2015 |
| Whole-exome sequencing identifies a novel genotype-phenotype correlation in the entactin domain of the known deafness gene TECTA. | Whole-exome sequencing identifies a novel genotype-phenotype correlation in the entactin domain of the known deafness gene TECTA.
Choi BY, Kim J, Chung J, Kim AR, Mun SJ, Kang SI, Lee SH, Kim N, Oh SH., Free PMC Article | 06/20/2015 |
| Identified the c.211delC mutation in the KCNQ4 gene and the c.2967C>A (p.H989Q) mutation in the TECTA gene to be associated with high-frequency sensorineural hearing loss in a Japanese family. | A Japanese family showing high-frequency hearing loss with KCNQ4 and TECTA mutations.
Ishikawa K, Naito T, Nishio SY, Iwasa Y, Nakamura K, Usami S, Ichimura K. | 01/10/2015 |
| A rare novel mutation in TECTA causes autosomal dominant nonsyndromic hearing loss in a Mongolian family. | A rare novel mutation in TECTA causes autosomal dominant nonsyndromic hearing loss in a Mongolian family.
Bai H, Yang X, Temuribagen, Guilan, Suyalatu, Narisu, Wu H, Chen Y, Liu Y, Wu Q., Free PMC Article | 08/9/2014 |
| Data indicate that sequencing of candidate gene TECTA (alpha-tectorin) revealed a heterozygous c.5945C>A substitution in exon 19, causing amino acid substitution of Ala to Asp at a conservative position 1982. | Identification of a Novel TECTA mutation in a Chinese DFNA8/12 family with prelingual progressive sensorineural hearing impairment.
Li Z, Guo Y, Lu Y, Li J, Jin Z, Li H, Lu Y, Dai P, Han D, Cheng J, Yuan H., Free PMC Article | 04/26/2014 |
| this study failed to replicate a GWAS reporting an association between the 2 SNPs rs2296308 in RWDD3 and rs1829 in the intron of TECTA and time to neuropathy in ovarian cancer patients treated with paclitaxel | GWAS-based association between RWDD3 and TECTA variants and paclitaxel induced neuropathy could not be confirmed in Scandinavian ovarian cancer patients.
Bergmann TK, Vach W, Feddersen S, Eckhoff L, Gréen H, Herrstedt J, Brosen K. | 01/4/2014 |
| we have reported the prevalence of TECTA mutations in Japanese autosomal dominant nonsyndromic hearing loss (ADNSHL) patients detected by genetic screening, and confirmed the genotype-phenotype correlations. | TECTA mutations in Japanese with mid-frequency hearing loss affected by zona pellucida domain protein secretion.
Moteki H, Nishio SY, Hashimoto S, Takumi Y, Iwasaki S, Takeichi N, Fukuda S, Usami S. | 02/16/2013 |
| analysis allowed us to identify an aberrant transcript with skipping of exon 16, without affecting the reading frame. One of the dominant TECTA mutations already described, a synonymous substitution in exon 16 | Aberrant transcript produced by a splice donor site deletion in the TECTA gene is associated with autosomal dominant deafness in a Brazilian family.
Lezirovitz K, Batissoco AC, Lima FT, Auricchio MT, Nonose RW, dos Santos SR, Guilherme L, Oiticica J, Mingroni-Netto RC. | 01/26/2013 |
| CEACAM16 can probably form higher order structures with other tectorial membrane proteins such as alpha-tectorin and beta-tectorin and influences the physical properties of the tectorial membrane | Loss of mammal-specific tectorial membrane component carcinoembryonic antigen cell adhesion molecule 16 (CEACAM16) leads to hearing impairment at low and high frequencies.
Kammerer R, Rüttiger L, Riesenberg R, Schäuble C, Krupar R, Kamp A, Sunami K, Eisenried A, Hennenberg M, Grunert F, Bress A, Battaglia S, Schrewe H, Knipper M, Schneider MR, Zimmermann W., Free PMC Article | 09/22/2012 |
| Here, we identified a missense mutation (p.C1691F) and a splicing mutation (c.6162+3insT), one in each TECTA allele, in the patient with hearing loss. | Identification and functional characterization of novel compound heterozygotic mutations in the TECTA gene.
Sagong B, Park HJ, Lee KY, Kim UK. | 03/17/2012 |
| mutations in the N-terminal region of alpha-tectorin lead to mid-frequency nonsyndromic hearing loss | DFNA8/12 caused by TECTA mutations is the most identified subtype of nonsyndromic autosomal dominant hearing loss.
Hildebrand MS, Morín M, Meyer NC, Mayo F, Modamio-Hoybjor S, Mencía A, Olavarrieta L, Morales-Angulo C, Nishimura CJ, Workman H, DeLuca AP, del Castillo I, Taylor KR, Tompkins B, Goodman CW, Schrauwen I, Wesemael MV, Lachlan K, Shearer AE, Braun TA, Huygen PL, Kremer H, Van Camp G, Moreno F, Casavant TL, Smith RJ, Moreno-Pelayo MA., Free PMC Article | 10/15/2011 |
| data identify CEACAM16 as an alpha-tectorin-interacting protein that concentrates at the point of attachment of the TM to the stereocilia and, when mutated, results in ADNSHL at the DFNA4 locus | Carcinoembryonic antigen-related cell adhesion molecule 16 interacts with alpha-tectorin and is mutated in autosomal dominant hearing loss (DFNA4).
Zheng J, Miller KK, Yang T, Hildebrand MS, Shearer AE, DeLuca AP, Scheetz TE, Drummond J, Scherer SE, Legan PK, Goodyear RJ, Richardson GP, Cheatham MA, Smith RJ, Dallos P., Free PMC Article | 05/28/2011 |
| Mutation analysis of the TECTA gene was performed in 62 Korean patients with hereditary hearing loss. | Two novel missense mutations in the TECTA gene in Korean families with autosomal dominant nonsyndromic hearing loss.
Sagong B, Park R, Kim YH, Lee KY, Baek JI, Cho HJ, Cho IJ, Kim UK, Lee SH, Sagong B, Park R, Kim YH, Lee KY, Baek JI, Cho HJ, Cho IJ, Kim UK, Lee SH. | 02/26/2011 |
| Observational study of gene-disease association. (HuGE Navigator) | Two novel missense mutations in the TECTA gene in Korean families with autosomal dominant nonsyndromic hearing loss.
Sagong B, Park R, Kim YH, Lee KY, Baek JI, Cho HJ, Cho IJ, Kim UK, Lee SH, Sagong B, Park R, Kim YH, Lee KY, Baek JI, Cho HJ, Cho IJ, Kim UK, Lee SH. | 12/5/2010 |
| Observational study of genotype prevalence. (HuGE Navigator) | Genetic causes of nonsyndromic hearing loss in Iran in comparison with other populations.
Mahdieh N, Rabbani B, Wiley S, Akbari MT, Zeinali S. | 09/15/2010 |
| The tectorial membrane was shortened in heterozygous Tecta(C1509G/+) mice, reaching only the first row of outer hair cells. | Deficient forward transduction and enhanced reverse transduction in the alpha tectorin C1509G human hearing loss mutation.
Xia A, Gao SS, Yuan T, Osborn A, Bress A, Pfister M, Maricich SM, Pereira FA, Oghalai JS., Free PMC Article | 05/31/2010 |