| TIE2 expression in hypertensive ICH and its therapeutic modulation with AKB-9778: Implications for brain vascular health. | TIE2 expression in hypertensive ICH and its therapeutic modulation with AKB-9778: Implications for brain vascular health.
Wu J, Wang H, Wang N, Wang Z, Zhu Q. | 02/28/2024 |
| Type I Interferons induce endothelial destabilization in Systemic Lupus Erythematosus in a Tie2-dependent manner. | Type I Interferons induce endothelial destabilization in Systemic Lupus Erythematosus in a Tie2-dependent manner.
Rafael-Vidal C, Martínez-Ramos S, Malvar-Fernández B, Altabás-González I, Mouriño C, Veale DJ, Floudas A, Fearon U, Reigosa JMP, García S., Free PMC Article | 01/3/2024 |
| Expression of Tie2 (angiopoietin receptor) on the monocyte subpopulations from ischemic stroke patients: Histological and flowcytometric studies. | Expression of Tie2 (angiopoietin receptor) on the monocyte subpopulations from ischemic stroke patients: Histological and flowcytometric studies.
Alrafiah AR. | 11/22/2023 |
| METTL3-Mediated RNA m6A Modification Regulates the Angiogenic Behaviors of Retinal Endothelial Cells by Methylating MMP2 and TIE2. | METTL3-Mediated RNA m6A Modification Regulates the Angiogenic Behaviors of Retinal Endothelial Cells by Methylating MMP2 and TIE2.
Lin Y, Luo G, Liu Q, Yang R, Sol Reinach P, Yan D., Free PMC Article | 11/7/2023 |
| Somatic mutation spectrum of a Chinese cohort of pediatrics with vascular malformations. | Somatic mutation spectrum of a Chinese cohort of pediatrics with vascular malformations.
Zhang B, He R, Xu Z, Sun Y, Wei L, Li L, Liu Y, Guo W, Song L, Wang H, Lin Z, Ma L., Free PMC Article | 09/25/2023 |
| Polymorphisms in TIE2 and ANGPT-1 genes are associated with protection against diabetic retinopathy in a Brazilian population. | Polymorphisms in TIE2 and ANGPT-1 genes are associated with protection against diabetic retinopathy in a Brazilian population.
Dieter C, Lemos NE, de Faria Corrêa NR, Assmann TS, Pellenz FM, Canani LH, de Almeida Brondani L, Bauer AC, Crispim D., Free PMC Article | 06/3/2023 |
| Hsa_circ_0070661 inhibits cancer progression through miR-556-5p/TEK axis in lung adenocarcinoma. | Hsa_circ_0070661 inhibits cancer progression through miR-556-5p/TEK axis in lung adenocarcinoma.
Chen Y, Wu Y. | 05/17/2023 |
| [Expression of Tyrosine Kinase Receptor 2 in Oral Squamous Cell Carcinoma and the Effect on Cell Proliferation and Migration and Epithelial-Mesenchymal Transition Process]. | [Expression of Tyrosine Kinase Receptor 2 in Oral Squamous Cell Carcinoma and the Effect on Cell Proliferation and Migration and Epithelial-Mesenchymal Transition Process].
Zheng M, Huang Y, Fei W, Shen Y, Nie X, Gao MY., Free PMC Article | 04/1/2023 |
| Tie2 Receptor in Tumor-Infiltrating Macrophages Is Dispensable for Tumor Angiogenesis and Tumor Relapse after Chemotherapy. | Tie2 Receptor in Tumor-Infiltrating Macrophages Is Dispensable for Tumor Angiogenesis and Tumor Relapse after Chemotherapy.
Jakab M, Rostalski T, Lee KH, Mogler C, Augustin HG., Free PMC Article | 07/23/2022 |
| Increased frequency of proangiogenic tunica intima endothelial kinase 2 (Tie2) expressing monocytes in individuals with type 2 diabetes mellitus. | Increased frequency of proangiogenic tunica intima endothelial kinase 2 (Tie2) expressing monocytes in individuals with type 2 diabetes mellitus.
Reijrink M, van Ark J, Lexis CPH, Visser LM, Lodewijk ME, van der Horst ICC, Zeebregts CJ, van Goor H, de Jager SCA, Pasterkamp G, Wolffenbuttel BHR, Hillebrands JL., Free PMC Article | 06/11/2022 |
| Angpt2/Tie2 autostimulatory loop controls tumorigenesis. | Angpt2/Tie2 autostimulatory loop controls tumorigenesis.
Karabid NM, Wiedemann T, Gulde S, Mohr H, Segaran RC, Geppert J, Rohm M, Vitale G, Gaudenzi G, Dicitore A, Ankerst DP, Chen Y, Braren R, Kaissis G, Schilling F, Schillmaier M, Eisenhofer G, Herzig S, Roncaroli F, Honegger JB, Pellegata NS., Free PMC Article | 05/14/2022 |
| Tie2-expressing monocytes/macrophages promote cerebral revascularization in peri-infarct lesions upon ischemic insult. | Tie2-expressing monocytes/macrophages promote cerebral revascularization in peri-infarct lesions upon ischemic insult.
Sheng Y, Duan X, Liu Y, Li F, Ma S, Shang X, Wang X, Liu Y, Xue R, Qin Z., Free PMC Article | 04/2/2022 |
| SIRT7 interacts with TEK (TIE2) to promote adriamycin induced metastasis in breast cancer. | SIRT7 interacts with TEK (TIE2) to promote adriamycin induced metastasis in breast cancer.
Yang F, Hu Y, Shao L, Zhuang J, Huo Q, He S, Chen S, Wang J, Xie N. | 03/19/2022 |
| The Angiopoietin-Tie2 axis contributes to placental vascular disruption and adverse birth outcomes in malaria in pregnancy. | The Angiopoietin-Tie2 axis contributes to placental vascular disruption and adverse birth outcomes in malaria in pregnancy.
Tran V, Weckman AM, Crowley VM, Cahill LS, Zhong K, Cabrera A, Elphinstone RE, Pearce V, Madanitsa M, Kalilani-Phiri L, Mwapasa V, Khairallah C, Conroy AL, Ter Kuile FO, Sled JG, Kain KC., Free PMC Article | 03/5/2022 |
| Tumor cell-derived exosomes deliver TIE2 protein to macrophages to promote angiogenesis in cervical cancer. | Tumor cell-derived exosomes deliver TIE2 protein to macrophages to promote angiogenesis in cervical cancer.
Du S, Qian J, Tan S, Li W, Liu P, Zhao J, Zeng Y, Xu L, Wang Z, Cai J. | 02/26/2022 |
| Mid trimester amniotic fluid soluble receptor tunica interna endothelial cell kinase-2 levels and risk for preeclampsia. | Mid trimester amniotic fluid soluble receptor tunica interna endothelial cell kinase-2 levels and risk for preeclampsia.
Stipoljev F, Vujisić S, Ježek D, Vičić A, Radmanić L, Papić N, Židovec Lepej S. | 02/26/2022 |
| Adaptor Protein ShcD/SHC4 Interacts with Tie2 Receptor to Synergistically Promote Glioma Cell Invasion. | Adaptor Protein ShcD/SHC4 Interacts with Tie2 Receptor to Synergistically Promote Glioma Cell Invasion.
Tilak M, Alural B, Wismer SE, Brasher MI, New LA, Sheridan SD, Perlis RH, Coppolino MG, Lalonde J, Jones N., Free PMC Article | 01/29/2022 |
| Bockenheimer disease is associated with a TEK variant. | Bockenheimer disease is associated with a TEK variant.
Sudduth CL, Konczyk DJ, Smits PJ, Eng W, Al-Ibraheemi A, Upton J, Greene AK., Free PMC Article | 01/15/2022 |
| Structural insights into the clustering and activation of Tie2 receptor mediated by Tie2 agonistic antibody. | Structural insights into the clustering and activation of Tie2 receptor mediated by Tie2 agonistic antibody.
Jo G, Bae J, Hong HJ, Han AR, Kim DK, Hong SP, Kim JA, Lee S, Koh GY, Kim HM., Free PMC Article | 12/25/2021 |
| Intrinsic differences in the mechanisms of Tie2 binding to angiopoietins exploited by directed evolution to create an Ang2-selective ligand trap. | Intrinsic differences in the mechanisms of Tie2 binding to angiopoietins exploited by directed evolution to create an Ang2-selective ligand trap.
Bate N, Lodge J, Brindle NPJ., Free PMC Article | 12/4/2021 |
| Tie2 activation protects against prothrombotic endothelial dysfunction in COVID-19. | Tie2 activation protects against prothrombotic endothelial dysfunction in COVID-19.
Schmaier AA, Pajares Hurtado GM, Manickas-Hill ZJ, Sack KD, Chen SM, Bhambhani V, Quadir J, Nath AK, Collier AY, Ngo D, Barouch DH, Shapiro NI, Gerszten RE, Yu XG, MGH COVID-19 Collection and Processing Team, Peters KG, Flaumenhaft R, Parikh SM., Free PMC Article | 11/6/2021 |
| Identification of TIE2 as a susceptibility gene for neovascular age-related macular degeneration and polypoidal choroidal vasculopathy. | Identification of TIE2 as a susceptibility gene for neovascular age-related macular degeneration and polypoidal choroidal vasculopathy.
Chen ZJ, Ma L, Brelen ME, Chen H, Tsujikawa M, Lai TY, Ho M, Sayanagi K, Hara C, Hashida N, Tam PO, Young AL, Nishida K, Tham CC, Pang CP, Chen LJ. | 09/25/2021 |
| AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations. | AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
Si Y, Huang J, Li X, Fu Y, Xu R, Du Y, Cheng J, Jiang H., Free PMC Article | 09/11/2021 |
| Effect of Whole Tissue Culture and Basic Fibroblast Growth Factor on Maintenance of Tie2 Molecule Expression in Human Nucleus Pulposus Cells. | Effect of Whole Tissue Culture and Basic Fibroblast Growth Factor on Maintenance of Tie2 Molecule Expression in Human Nucleus Pulposus Cells.
Sako K, Sakai D, Nakamura Y, Schol J, Matsushita E, Warita T, Horikita N, Sato M, Watanabe M., Free PMC Article | 06/5/2021 |
| SVEP1 as a Genetic Modifier of TEK-Related Primary Congenital Glaucoma. | SVEP1 as a Genetic Modifier of TEK-Related Primary Congenital Glaucoma.
Young TL, Whisenhunt KN, Jin J, LaMartina SM, Martin SM, Souma T, Limviphuvadh V, Suri F, Souzeau E, Zhang X, Dan Y, Anagnos E, Carmona S, Jody NM, Stangel N, Higuchi EC, Huang SJ, Siggs OM, Simões MJ, Lawson BM, Martin JS, Elahi E, Narooie-Nejad M, Motlagh BF, Quaggin SE, Potter HD, Silva ED, Craig JE, Egas C, Maroofian R, Maurer-Stroh S, Bradfield YS, Tompson SW., Free PMC Article | 05/8/2021 |