| Impact of Troponin in Cardiomyopathy Development Caused by Mutations in Tropomyosin. | Impact of Troponin in Cardiomyopathy Development Caused by Mutations in Tropomyosin.
Nefedova VV, Kopylova GV, Shchepkin DV, Kochurova AM, Kechko OI, Borzova VA, Ryabkova NS, Katrukha IA, Mitkevich VA, Bershitsky SY, Levitsky DI, Matyushenko AM., Free PMC Article | 01/11/2023 |
| MYC-Induced Upregulation of Lncrna ELFN1-AS1 Contributes to Tumor Growth in Colorectal Cancer via Epigenetically Silencing TPM1. | MYC-Induced Upregulation of Lncrna ELFN1-AS1 Contributes to Tumor Growth in Colorectal Cancer via Epigenetically Silencing TPM1.
Li C, Hong S, Hu H, Liu T, Yan G, Sun D. | 11/12/2022 |
| Genetic resiliency associated with dominant lethal TPM1 mutation causing atrial septal defect with high heritability. | Genetic resiliency associated with dominant lethal TPM1 mutation causing atrial septal defect with high heritability.
Teekakirikul P, Zhu W, Xu X, Young CB, Tan T, Smith AM, Wang C, Peterson KA, Gabriel GC, Ho S, Sheng Y, Moreau de Bellaing A, Sonnenberg DA, Lin JH, Fotiou E, Tenin G, Wang MX, Wu YL, Feinstein T, Devine W, Gou H, Bais AS, Glennon BJ, Zahid M, Wong TC, Ahmad F, Rynkiewicz MJ, Lehman WJ, Keavney B, Alastalo TP, Freckmann ML, Orwig K, Murray S, Ware SM, Zhao H, Feingold B, Lo CW., Free PMC Article | 05/7/2022 |
| The prognostic value of TPM1-4 in hepatocellular carcinoma. | The prognostic value of TPM1-4 in hepatocellular carcinoma.
Tian Z, Zhao J, Wang Y., Free PMC Article | 03/19/2022 |
| Genotype-phenotype correlations in hypertrophic cardiomyopathy: a multicenter study in Portugal and Spain of the TPM1 p.Arg21Leu variant. | Genotype-phenotype correlations in hypertrophic cardiomyopathy: a multicenter study in Portugal and Spain of the TPM1 p.Arg21Leu variant.
Lamounier Junior A, Guitián González A, Rodríguez Vilela A, Repáraz Andrade A, Rubio Alcaide Á, Berta Sousa A, Benito López C, Alonso García D, Fernández Ferro G, Cruz I, Cárdenas Reyes IJ, Salazar-Mendiguchía García J, Larrañaga-Moreira JM, Ochoa JP, Palomino-Doza J, de la Higuera Romero L, Nicolás Cicerchia M, Restrepo Córdoba MA, Peña-Peña ML, Noël Brögger M, Loureiro M, Mogollón Jiménez MV, Bilbao Quesada R, Franco Gutiérrez R, García Hernández S, Ripoll-Vera T, Fernández X, Azevedo O, García Pavía P, Lopes LR, Ortiz M, Brito D, Barriales-Villa R, Monserrat Iglesias L. | 02/26/2022 |
| Identification of a novel missense mutation in the TPM1 gene via exome sequencing in a Chinese family with dilated cardiomyopathy: A case report and literature review. | Identification of a novel missense mutation in the TPM1 gene via exome sequencing in a Chinese family with dilated cardiomyopathy: A case report and literature review.
Man Y, Yi C, Fan M, Yang T, Liu P, Liu S, Wang G., Free PMC Article | 02/19/2022 |
| The effects of the tropomyosin cardiomyopathy mutations on the calcium regulation of actin-myosin interaction in the atrium and ventricle differ. | The effects of the tropomyosin cardiomyopathy mutations on the calcium regulation of actin-myosin interaction in the atrium and ventricle differ.
Kopylova GV, Berg VY, Kochurova AM, Matyushenko AM, Bershitsky SY, Shchepkin DV. | 02/12/2022 |
| Association Between TPM1 Gene Polymorphisms and Idiopathic Congenital Talipes Equinovarus Risk in a Chinese Population. | Association Between TPM1 Gene Polymorphisms and Idiopathic Congenital Talipes Equinovarus Risk in a Chinese Population.
Li J, Zhu G, Kang X, Shen X, Chen S, Tang S, Gong Q, Li Y, Xu H. | 12/11/2021 |
| Loss of crossbridge inhibition drives pathological cardiac hypertrophy in patients harboring the TPM1 E192K mutation. | Loss of crossbridge inhibition drives pathological cardiac hypertrophy in patients harboring the TPM1 E192K mutation.
Sewanan LR, Park J, Rynkiewicz MJ, Racca AW, Papoutsidakis N, Schwan J, Jacoby DL, Moore JR, Lehman W, Qyang Y, Campbell SG., Free PMC Article | 10/30/2021 |
| Circ0001320 inhibits lung cancer cell growth and invasion by regulating TNFAIP1 and TPM1 expression through sponging miR-558. | Circ0001320 inhibits lung cancer cell growth and invasion by regulating TNFAIP1 and TPM1 expression through sponging miR-558.
Mao Y, He JX, Zhu M, Dong YQ, He JX. | 08/7/2021 |
| Dynamics of Tpm1.8 domains on actin filaments with single-molecule resolution. | Dynamics of Tpm1.8 domains on actin filaments with single-molecule resolution.
Bareja I, Wioland H, Janco M, Nicovich PR, Jégou A, Romet-Lemonne G, Walsh J, Böcking T., Free PMC Article | 06/12/2021 |
| The effect of tropomyosin variants on cardiomyocyte function and structure that underlie different clinical cardiomyopathy phenotypes. | The effect of tropomyosin variants on cardiomyocyte function and structure that underlie different clinical cardiomyopathy phenotypes.
Dorsch LM, Kuster DWD, Jongbloed JDH, Boven LG, van Spaendonck-Zwarts KY, Suurmeijer AJH, Vink A, du Marchie Sarvaas GJ, van den Berg MP, van der Velden J, Brundel BJJM, van der Zwaag PA. | 06/5/2021 |
| M8R tropomyosin mutation disrupts actin binding and filament regulation: The beginning affects the middle and end. | M8R tropomyosin mutation disrupts actin binding and filament regulation: The beginning affects the middle and end.
Racca AW, Rynkiewicz MJ, LaFave N, Ghosh A, Lehman W, Moore JR., Free PMC Article | 05/22/2021 |
| Tropomyosin pseudo-phosphorylation can rescue the effects of cardiomyopathy-associated mutations. | Tropomyosin pseudo-phosphorylation can rescue the effects of cardiomyopathy-associated mutations.
Nefedova VV, Koubassova NA, Borzova VA, Kleymenov SY, Tsaturyan AK, Matyushenko AM, Levitsky DI. | 04/17/2021 |
| Impact of A134 and E218 Amino Acid Residues of Tropomyosin on Its Flexibility and Function. | Impact of A134 and E218 Amino Acid Residues of Tropomyosin on Its Flexibility and Function.
Marchenko MA, Nefedova VV, Yampolskaya DS, Kopylova GV, Shchepkin DV, Bershitsky SY, Koubassova NA, Tsaturyan AK, Levitsky DI, Matyushenko AM., Free PMC Article | 03/13/2021 |
| Regulation of Actin Filament Length by Muscle Isoforms of Tropomyosin and Cofilin. | Regulation of Actin Filament Length by Muscle Isoforms of Tropomyosin and Cofilin.
Robaszkiewicz K, Śliwinska M, Moraczewska J., Free PMC Article | 02/20/2021 |
| TPM1 is a Novel Predictive Biomarker for Gastric Cancer Diagnosis and Prognosis. | TPM1 is a Novel Predictive Biomarker for Gastric Cancer Diagnosis and Prognosis.
Hu L, Fang L, Zhang ZP, Yan ZL. | 01/9/2021 |
| Tropomyosin concentration but not formin nucleators mDia1 and mDia3 determines the level of tropomyosin incorporation into actin filaments. | Tropomyosin concentration but not formin nucleators mDia1 and mDia3 determines the level of tropomyosin incorporation into actin filaments.
Meiring JCM, Bryce NS, Niño JLG, Gabriel A, Tay SS, Hardeman EC, Biro M, Gunning PW., Free PMC Article | 10/24/2020 |
| actin's D- and H-loop are the sites involved in regulation of cofilin activity by tropomyosin isoforms | Tropomyosin isoforms regulate cofilin 1 activity by modulating actin filament conformation.
Ostrowska-Podhorodecka Z, Śliwinska M, Reisler E, Moraczewska J., Free PMC Article | 07/18/2020 |
| These data show for the first time a significant difference in the thermal unfolding between muscle and non-muscle Tpm isoforms. | Thermal unfolding of various human non-muscle isoforms of tropomyosin.
Nefedova VV, Marchenko MA, Kleymenov SY, Datskevich PN, Levitsky DI, Matyushenko AM. | 06/20/2020 |
| our findings support an association between genetic polymorphisms of TPM1 genes and the risk of NSCL/P. | Association of single nucleotide polymorphisms in TPM1 rs11071720, rs3803499, rs12148828, and rs1972041 with the risk of nonsyndromic cleft lip with or without cleft palate in a sample of the Iranian population, a preliminary report.
Rafighdoost H, Tabatabaei F, Bahari G, Hashemi M. | 05/9/2020 |
| Low TPM1 expression is associated with migration and invasion of gastric cancer. | miRNA‑183‑5p.1 promotes the migration and invasion of gastric cancer AGS cells by targeting TPM1.
Lin J, Shen J, Yue H, Cao Z., Free PMC Article | 04/18/2020 |
| Structural and functional properties of alpha-beta-Tpm heterodimers with myopathic mutations Q147P and K49del in the beta-chain differ significantly from the properties of beta-beta-Tpm homodimers with the same substitutions in both beta-chains. Mutations Q147P and K49del strongly increased the stability of calorimetric domain previously assigned to the N-terminal part of Tpm molecule. | Structural and functional properties of αβ-heterodimers of tropomyosin with myopathic mutations Q147P and K49del in the β-chain.
Matyushenko AM, Shchepkin DV, Susorov DS, Nefedova VV, Kopylova GV, Berg VY, Kleymenov SY, Levitsky DI. | 11/23/2019 |
| The single nucleotide polymorphisms of TPM1 gene rs6738 locus is associated with the risk of dilated cardiomyopathy, which may be related to the abnormal increase of serum miR-21 levels in dilated cardiomyopathy patients. The risk of dilated cardiomyopathy development in the rs6738 locus G allele carriers were 1.69 times more than A allele carriers. | Association of single nucleotide polymorphisms in the 3'UTR region of TPM1 gene with dilated cardiomyopathy: A case-control study.
Yao Q, Zhang W, Zhang T., Free PMC Article | 11/16/2019 |
| Platelet tropomyosin-1 constitutes a gender-related and stage-dependent protein in cognitive impairment. | Gender-related increase of tropomyosin-1 abundance in platelets of Alzheimer's disease and mild cognitive impairment patients.
Reumiller CM, Schmidt GJ, Dhrami I, Umlauf E, Rappold E, Zellner M. | 07/20/2019 |