| METTL3-deficiency m6A-dependently degrades MALAT1 to suppress NLRP3-mediated pyroptotic cell death and inflammation in Mycobacterium tuberculosis (H37Ra strain)-infected mouse macrophages. | METTL3-deficiency m6A-dependently degrades MALAT1 to suppress NLRP3-mediated pyroptotic cell death and inflammation in Mycobacterium tuberculosis (H37Ra strain)-infected mouse macrophages.
Han L, Tieliwaerdi N, Li X. | 04/4/2024 |
| Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis. | Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis.
Zhao Y, Ning J, Teng H, Deng Y, Sheldon M, Shi L, Martinez C, Zhang J, Tian A, Sun Y, Nakagawa S, Yao F, Wang H, Ma L., Free PMC Article | 03/18/2024 |
| LncRNA Malat1 suppresses pyroptosis and T cell-mediated killing of incipient metastatic cells. | LncRNA Malat1 suppresses pyroptosis and T cell-mediated killing of incipient metastatic cells.
Kumar D, Gurrapu S, Wang Y, Bae SY, Pandey PR, Chen H, Mondal J, Han H, Wu CJ, Karaiskos S, Yang F, Sahin A, Wistuba II, Gao J, Tripathy D, Gao H, Izar B, Giancotti FG. | 02/29/2024 |
| Malat1 regulates PMN-MDSC expansion and immunosuppression through p-STAT3 ubiquitination in sepsis. | Malat1 regulates PMN-MDSC expansion and immunosuppression through p-STAT3 ubiquitination in sepsis.
Wang Y, Zhang C, Liu T, Yu Z, Wang K, Ying J, Wang Y, Zhu T, Li J, Hu XL, Zhou Y, Lu G., Free PMC Article | 02/26/2024 |
| The lncRNA Malat1 inhibits miR-15/16 to enhance cytotoxic T cell activation and memory cell formation. | The lncRNA Malat1 inhibits miR-15/16 to enhance cytotoxic T cell activation and memory cell formation.
Wheeler BD, Gagnon JD, Zhu WS, Muñoz-Sandoval P, Wong SK, Simeonov DS, Li Z, DeBarge R, Spitzer MH, Marson A, Ansel KM., Free PMC Article | 12/27/2023 |
| Anti-apoptotic capacity of MALAT1 on hippocampal neurons correlates with CASP3 DNA methylation in a mouse model of autism. | Anti-apoptotic capacity of MALAT1 on hippocampal neurons correlates with CASP3 DNA methylation in a mouse model of autism.
Ming Y, Deng Z, Tian X, Jia Y, Ning M, Cheng S. | 12/20/2023 |
| Targeted Inhibition of lncRNA Malat1 Alters the Tumor Immune Microenvironment in Preclinical Syngeneic Mouse Models of Triple-Negative Breast Cancer. | Targeted Inhibition of lncRNA Malat1 Alters the Tumor Immune Microenvironment in Preclinical Syngeneic Mouse Models of Triple-Negative Breast Cancer.
Adewunmi O, Shen Y, Zhang XH, Rosen JM., Free PMC Article | 11/6/2023 |
| Synapse-Enriched m[6]A-Modified Malat1 Interacts with the Novel m[6]A Reader, DPYSL2, and Is Required for Fear-Extinction Memory. | Synapse-Enriched m(6)A-Modified Malat1 Interacts with the Novel m(6)A Reader, DPYSL2, and Is Required for Fear-Extinction Memory.
Madugalle SU, Liau WS, Zhao Q, Li X, Gong H, Marshall PR, Periyakaruppiah A, Zajaczkowski EL, Leighton LJ, Ren H, Musgrove MRB, Davies JWA, Kim G, Rauch S, He C, Dickinson BC, Fulopova B, Fletcher LN, Williams SR, Spitale RC, Bredy TW., | 10/30/2023 |
| LncRNA MALAT1/microRNA-30b axis regulates macrophage polarization and function. | LncRNA MALAT1/microRNA-30b axis regulates macrophage polarization and function.
Ahmad I, Naqvi RA, Valverde A, Naqvi AR., Free PMC Article | 10/30/2023 |
| Long non-coding RNA MALAT1 protects against Abeta1-42 induced toxicity by regulating the expression of receptor tyrosine kinase EPHA2 via quenching miR-200a/26a/26b in Alzheimer's disease. | Long non-coding RNA MALAT1 protects against Aβ(1-42) induced toxicity by regulating the expression of receptor tyrosine kinase EPHA2 via quenching miR-200a/26a/26b in Alzheimer's disease.
Chanda K, Jana NR, Mukhopadhyay D. | 10/30/2023 |
| Aerobic exercise improves cognitive impairment in mice with type 2 diabetes by regulating the MALAT1/miR-382-3p/BDNF signaling pathway in serum-exosomes. | Aerobic exercise improves cognitive impairment in mice with type 2 diabetes by regulating the MALAT1/miR-382-3p/BDNF signaling pathway in serum-exosomes.
Wang M, Xie K, Zhao S, Jia N, Zong Y, Gu W, Cai Y., Free PMC Article | 09/28/2023 |
| LncRNA MALAT1 Promoted Neuronal Necroptosis in Cerebral Ischemia-reperfusion Mice by Stabilizing HSP90. | LncRNA MALAT1 Promoted Neuronal Necroptosis in Cerebral Ischemia-reperfusion Mice by Stabilizing HSP90.
Huang S, Hou D, Zhang L, Pei C, Liang J, Li J, Yang G, Yu D. | 09/25/2023 |
| Lnc-Malat1 promotes slow myofiber-type transformation through sponging miR-129-5p in C2C12 myotubes. | Lnc-Malat1 promotes slow myofiber-type transformation through sponging miR-129-5p in C2C12 myotubes.
Yue Y, Wang Y, Wen C, Meng Y, Peng Y, Li X. | 09/11/2023 |
| Induction of lncRNA MALAT1 by hypoxia promotes bone formation by regulating the miR-22-3p/CEBPD axis. | Induction of lncRNA MALAT1 by hypoxia promotes bone formation by regulating the miR-22-3p/CEBPD axis.
Huang J, Shen HL, Feng ML, Li Z, An S, Cao GL. | 09/7/2023 |
| LncRNA NEAT-2 regulate the function of endothelial progenitor cells in experimental Sepsis model. | LncRNA NEAT-2 regulate the function of endothelial progenitor cells in experimental Sepsis model.
Yin XY, Liu Y, Lu ZM, Pang T, Cui HT, Xue XC, Fang GE, Luo TH. | 08/3/2023 |
| Mesenchymal stem cell-derived exosome alleviates sepsis- associated acute liver injury by suppressing MALAT1 through microRNA-26a-5p: an innovative immunopharmacological intervention and therapeutic approach for sepsis. | Mesenchymal stem cell-derived exosome alleviates sepsis- associated acute liver injury by suppressing MALAT1 through microRNA-26a-5p: an innovative immunopharmacological intervention and therapeutic approach for sepsis.
Cai J, Tang D, Hao X, Liu E, Li W, Shi J., Free PMC Article | 07/10/2023 |
| MALAT1 promotes platelet activity and thrombus formation through PI3k/Akt/GSK-3beta signalling pathway. | MALAT1 promotes platelet activity and thrombus formation through PI3k/Akt/GSK-3β signalling pathway.
Sun Y, Wang T, Lv Y, Li J, Jiang X, Jiang J, Zhang D, Bian W, Zhang C., Free PMC Article | 06/26/2023 |
| LncRNA MALAT1 improves cerebral ischemia-reperfusion injury and cognitive dysfunction by regulating miR-142-3p/SIRT1 axis. | LncRNA MALAT1 improves cerebral ischemia-reperfusion injury and cognitive dysfunction by regulating miR-142-3p/SIRT1 axis.
Meng S, Wang B, Li W. | 06/26/2023 |
| LncRNA MALAT1 Targets miR-9-3p to Upregulate SAP97 in the Hippocampus of Mice with Vascular Dementia. | LncRNA MALAT1 Targets miR-9-3p to Upregulate SAP97 in the Hippocampus of Mice with Vascular Dementia.
Wang P, Mao S, Yi T, Wang L. | 06/23/2023 |
| Mechanism of METTL14 and m6A modification of lncRNA MALAT1 in the proliferation of oral squamous cell carcinoma cells. | Mechanism of METTL14 and m6A modification of lncRNA MALAT1 in the proliferation of oral squamous cell carcinoma cells.
Li J, Momen-Heravi F, Wu X, He K. | 06/15/2023 |
| Metastasis-associated lung adenocarcinoma transcript 1 induces methyl-CpG-binding domain protein 4 in mice with recurrent spontaneous abortion caused by anti-phospholipid antibody positivity. | Metastasis-associated lung adenocarcinoma transcript 1 induces methyl-CpG-binding domain protein 4 in mice with recurrent spontaneous abortion caused by anti-phospholipid antibody positivity.
Han Y, Wang Y, Zhang C, Li Y, Guo J, Tian C. | 05/17/2023 |
| MALAT1 Mediates alpha-Synuclein Expression through miR-23b-3p to Induce Autophagic Impairment and the Inflammatory Response in Microglia to Promote Apoptosis in Dopaminergic Neuronal Cells. | MALAT1 Mediates α-Synuclein Expression through miR-23b-3p to Induce Autophagic Impairment and the Inflammatory Response in Microglia to Promote Apoptosis in Dopaminergic Neuronal Cells.
Geng X, Zou Y, Li S, Qi R, Yu H, Li J., Free PMC Article | 04/19/2023 |
| Fate mapping RNA-sequencing reveal Malat1 regulates Sca1[+] progenitor cells to vascular smooth muscle cells transition in vascular remodeling. | Fate mapping RNA-sequencing reveal Malat1 regulates Sca1(+) progenitor cells to vascular smooth muscle cells transition in vascular remodeling.
Lyu L, Li Z, Wen Z, He Y, Wang X, Jiang L, Zhou X, Huang C, Wu Y, Chen T, Guo X., Free PMC Article | 04/12/2023 |
| Malat1 deficiency prevents neonatal heart regeneration by inducing cardiomyocyte binucleation. | Malat1 deficiency prevents neonatal heart regeneration by inducing cardiomyocyte binucleation.
Aslan GS, Jaé N, Manavski Y, Fouani Y, Shumliakivska M, Kettenhausen L, Kirchhof L, Günther S, Fischer A, Luxán G, Dimmeler S., Free PMC Article | 03/10/2023 |
| Long noncoding RNA MALAT1 inhibition attenuates sepsis-induced acute lung injury through modulating the miR-129-5p/PAX6/ZEB2 axis. | Long noncoding RNA MALAT1 inhibition attenuates sepsis-induced acute lung injury through modulating the miR-129-5p/PAX6/ZEB2 axis.
Li Y, Xiao W, Lin X. | 03/7/2023 |