| WNT2B activates macrophages via NF-kappaB signaling pathway in inflammatory bowel disease. | WNT2B activates macrophages via NF-κB signaling pathway in inflammatory bowel disease.
Lan L, Huang C, Liu D, Cheng Y, Tang R, Gu J, Geng L, Cheng Y, Gong S. | 03/18/2024 |
| Upregulation of Wnt2b exerts neuroprotective effect by alleviating mitochondrial dysfunction in Alzheimer's disease. | Upregulation of Wnt2b exerts neuroprotective effect by alleviating mitochondrial dysfunction in Alzheimer's disease.
Xu LZ, Li BQ, Li FY, Quan MN, Qin W, Li Y, Li WW, Zhao Y, Wei YP, Jia JP., Free PMC Article | 07/7/2023 |
| [Mechanism of intestinal injury induced by WNT2B high-expressed fibroblasts in Crohn's disease]. | [Mechanism of intestinal injury induced by WNT2B high-expressed fibroblasts in Crohn's disease].
Cheng YL, Xiao SZ, Liu DQ, Geng LL, Gu JB, Tang R, Lan L, Zhu Y, Chen PY, He ZH, Gong ST, Cheng Y. | 07/5/2023 |
| [Fibroblasts overpressing WNT2b cause impairment of intestinal mucosal barrier]. | [Fibroblasts overpressing WNT2b cause impairment of intestinal mucosal barrier].
Xiao S, Cheng Y, Zhu Y, Tang R, Gu J, Lan L, He Z, Liu D, Geng L, Cheng Y, Gong S., Free PMC Article | 03/27/2023 |
| High Glucose-Induced Human Kidney Cell Apoptosis and Inflammatory Injury Are Alleviated by Circ_0008529 Knockdown via Circ_0008529-Mediated miR-485-5p/WNT2B Signaling. | High Glucose-Induced Human Kidney Cell Apoptosis and Inflammatory Injury Are Alleviated by Circ_0008529 Knockdown via Circ_0008529-Mediated miR-485-5p/WNT2B Signaling.
Wang W, Lu H. | 12/10/2022 |
| Wnt2b and Wnt5a expression is highly associated with M2 TAMs in nonsmall cell lung cancer. | Wnt2b and Wnt5a expression is highly associated with M2 TAMs in non‑small cell lung cancer.
Sumitomo R, Huang CL, Ando H, Ishida T, Cho H, Date H., Free PMC Article | 10/1/2022 |
| Circ_0000064 knockdown attenuates high glucose-induced proliferation, inflammation and extracellular matrix deposition of mesangial cells through miR-424-5p-mediated WNT2B inhibition in cell models of diabetic nephropathy. | Circ_0000064 knockdown attenuates high glucose-induced proliferation, inflammation and extracellular matrix deposition of mesangial cells through miR-424-5p-mediated WNT2B inhibition in cell models of diabetic nephropathy.
Li J, Min Y, Zhao Q. | 10/1/2022 |
| Novel variants in the stem cell niche factor WNT2B define the disease phenotype as a congenital enteropathy with ocular dysgenesis. | Novel variants in the stem cell niche factor WNT2B define the disease phenotype as a congenital enteropathy with ocular dysgenesis.
Zhang YJ, Jimenez L, Azova S, Kremen J, Chan YM, Elhusseiny AM, Saeed H, Goldsmith J, Al-Ibraheemi A, O'Connell AE, Kovbasnjuk O, Rodan L, Agrawal PB, Thiagarajah JR., Free PMC Article | 02/5/2022 |
| miR-27b-5p inhibits BeWo cells fusion by regulating WNT2B and enzyme involved in progesterone synthesis. | miR-27b-5p inhibits BeWo cells fusion by regulating WNT2B and enzyme involved in progesterone synthesis.
Verma S, Mishra R, Malik A, Chaudhary P, Malhotra SS, Panda AK, Gupta SK. | 01/22/2022 |
| Contribution of WNT2B Genetic Variants to Ischemic Stroke Occurrence in a Chinese Han Population. | Contribution of WNT2B Genetic Variants to Ischemic Stroke Occurrence in a Chinese Han Population.
Yuan H, Fan P, Yao L, Lv Y, Wei H, Zheng J, Han X. | 01/8/2022 |
| miR-188-5p inhibits proliferation, migration, and invasion in gallbladder carcinoma by targeting Wnt2b and Smad2. | miR-188-5p inhibits proliferation, migration, and invasion in gallbladder carcinoma by targeting Wnt2b and Smad2.
Li XL, Li SZ, Wu CX, Xing XH. | 12/4/2021 |
| MiR-449b-5p inhibits human glioblastoma cell proliferation by inactivating WNT2B/Wnt/beta-catenin signaling pathway. | MiR-449b-5p inhibits human glioblastoma cell proliferation by inactivating WNT2B/Wnt/β-catenin signaling pathway.
Hou WZ, Chen XL, Qin LS, Xu ZJ, Liao GM, Chen D, Hu LJ, Mao ZM, -S Huang J, Yuan Q, Liao C, Yao QM. | 04/3/2021 |
| Canonical Wnts Mediate CD8(+) T Cell Noncytolytic Anti-HIV-1 Activity and Correlate with HIV-1 Clinical Status. | Canonical Wnts Mediate CD8(+) T Cell Noncytolytic Anti-HIV-1 Activity and Correlate with HIV-1 Clinical Status.
Wallace J, Narasipura SD, Sha BE, French AL, Al-Harthi L., Free PMC Article | 04/3/2021 |
| WNT2b Activates Epithelial-mesenchymal Transition Through FZD4: Relevance in Penetrating Crohn s Disease. | WNT2b Activates Epithelial-mesenchymal Transition Through FZD4: Relevance in Penetrating Crohn´s Disease.
Ortiz-Masià D, Salvador P, Macias-Ceja DC, Gisbert-Ferrándiz L, Esplugues JV, Manyé J, Alós R, Navarro-Vicente F, Mamie C, Scharl M, Cosin-Roger J, Calatayud S, Barrachina MD. | 11/28/2020 |
| While miR-370-3p upregulation led to decreased osteogenic differentiation, LINC00707 overexpression could reverse this suppression, indicating that LINC00707 acts as a competing endogenous RNA (ceRNA) for miR-370-3p. Moreover, LINC00707 could act as a ceRNA to upregulate WNT2B via miR-370-3p inhibition | Long noncoding RNA LINC00707 sponges miR-370-3p to promote osteogenesis of human bone marrow-derived mesenchymal stem cells through upregulating WNT2B.
Jia B, Wang Z, Sun X, Chen J, Zhao J, Qiu X., Free PMC Article | 05/9/2020 |
| MiR-338-3p enhances the sensitivity of ovarian cancer cells to cisplatin by downregulating WNT2B. | MiR-338-3p Enhances Ovarian Cancer Cell Sensitivity to Cisplatin by Downregulating WNT2B.
Niu Q, Liu Z, Gao J, Wang Q., Free PMC Article | 02/15/2020 |
| Overexpression of WNTB2 in KGN partially reversed the growth-inhibitory effects of miR-324 overexpression. miR-324 regulates the proliferation of KGN cells in PCOs and be essential in the management of PCOS. | Proliferation of Ovarian Granulosa Cells in Polycystic Ovarian Syndrome Is Regulated by MicroRNA-24 by Targeting Wingless-Type Family Member 2B (WNT2B).
Yuanyuan Z, Zeqin W, Xiaojie S, Liping L, Yun X, Jieqiong Z., Free PMC Article | 01/18/2020 |
| Individuals with homozygous nonsense mutations in WNT2B demonstrate severe intestinal dysregulation. | Neonatal-Onset Chronic Diarrhea Caused by Homozygous Nonsense WNT2B Mutations.
O'Connell AE, Zhou F, Shah MS, Murphy Q, Rickner H, Kelsen J, Boyle J, Doyle JJ, Gangwani B, Thiagarajah JR, Kamin DS, Goldsmith JD, Richmond C, Breault DT, Agrawal PB., Free PMC Article | 05/18/2019 |
| downregulation of ACSL5 and Wnt2B could play an important role in the development of bronchial-alveolar structures in congenital pulmonary airway malformations (CPAMs). | Expression Analysis of ACSL5 and Wnt2B in Human Congenital Pulmonary Airway Malformations.
Qu Y, Liu D, Jia H, Zhou X. | 04/27/2019 |
| The findings provided new insights into the pathophysiology of liver fibrosis by characterizing Wnt2b as a novel endogenous suppressor of TLR4 signaling, maintaining tissue homeostasis during the early stage of hepatic fibrosis-associated liver diseases. | Wnt2b attenuates HSCs activation and liver fibrosis through negative regulating TLR4 signaling.
Yuan Y, Han Q, Li S, Tian Z, Zhang J., Free PMC Article | 01/12/2019 |
| Wnt2B co-operates with Frizzled7 to mediate mesenchymal to epithelial transition in colorectal cancer. | Wnt is necessary for mesenchymal to epithelial transition in colorectal cancer cells.
Schwab RHM, Amin N, Flanagan DJ, Johanson TM, Phesse TJ, Vincan E. | 11/10/2018 |
| Altered WNT2B expression in bladder wall fibroblasts alters expression of the apoptosis inductor TNFSF10. | Impact of Altered WNT2B Expression on Bladder Wall Fibroblasts: Implications for Apoptosis Regulation in the Stroma of the Lower Urinary Tract.
Worst TS, Daskalova K, Steidler A, Berner-Leischner K, Röth R, Niesler B, Kriegmair MC, Erben P, Pfalzgraf D. | 07/28/2018 |
| we identified two independent SNPs (i.e., WNT2B rs1175649 G>T and BTRC rs61873997 G>A) that showed a predictive role in CM-specific survival, with an effect-allele-attributed hazards ratio (adjusted hazards ratio) of 1.99 (95% confidence interval = 1.41-2.81, P = 8.10 x 10(-5)) and 0.61 (0.46-0.80, 3.12x10(-4)), respectively. | Genetic Variants in WNT2B and BTRC Predict Melanoma Survival.
Shi Q, Liu H, Han P, Li C, Wang Y, Wu W, Zhu D, Amos CI, Fang S, Lee JE, Han J, Wei Q., Free PMC Article | 09/16/2017 |
| A549-Luc-positive cells showed cytotoxicity following exposure to the Ad-shWnt2B vector. The percentage of viable cells was significantly lower in A549-Luc cells treated with Ad-shWnt2B than with Ad-scramble (p<0.01 versus control or Ad-scramble, respectively). | Ad-shWnt2b Vector Therapy Demonstrates Antitumor Activity in Orthotopic Intrapleural Models as Monitored with the In Vitro Imaging System (IVIS).
Kobayashi M, Huang CL, Sonobe M, Kikuchi R, Date H. | 02/4/2017 |
| the present study detected abnormal upregulation in the levels of Wnt2b and Wnt7b, and hypothesized that the alterations may be due to the ectopic opening of chromatin structure. | Abnormal epigenetic regulation of the gene expression levels of Wnt2b and Wnt7b: Implications for neural tube defects.
Bai B, Chen S, Zhang Q, Jiang Q, Li H., Free PMC Article | 10/1/2016 |