| Exosomes from Intrahepatic Cholestasis of Pregnancy Induce Cell Apoptosis Through the miRNA-6891-5p/YWHAE Pathway. | Exosomes from Intrahepatic Cholestasis of Pregnancy Induce Cell Apoptosis Through the miRNA-6891-5p/YWHAE Pathway.
Ye N, Shi X, Gao J, Dong R, Wang G, Wang J, Luo L, Zhang T. | 04/30/2024 |
| The novel miR-873-5p-YWHAE-PI3K/AKT axis is involved in non-small cell lung cancer progression and chemoresistance by mediating autophagy. | The novel miR-873-5p-YWHAE-PI3K/AKT axis is involved in non-small cell lung cancer progression and chemoresistance by mediating autophagy.
Li Z, Liu J, Wang P, Zhang B, He G, Yang L. | 02/20/2024 |
| Comprehensive analysis of the function of helicobacter-associated ferroptosis gene YWHAE in gastric cancer through multi-omics integration, molecular docking, and machine learning. | Comprehensive analysis of the function of helicobacter-associated ferroptosis gene YWHAE in gastric cancer through multi-omics integration, molecular docking, and machine learning.
Liu D, Peng J, Xie J, Xie Y. | 02/20/2024 |
| 14-3-3epsilon: a protein with complex physiology function but promising therapeutic potential in cancer. | 14-3-3ε: a protein with complex physiology function but promising therapeutic potential in cancer.
Zhang Y, Yan M, Yu Y, Wang J, Jiao Y, Zheng M, Zhang S., Free PMC Article | 01/30/2024 |
| Nucleo-cytoplasmic shuttling of 14-3-3 epsilon carrying hnRNP C promotes autophagy. | Nucleo-cytoplasmic shuttling of 14-3-3 epsilon carrying hnRNP C promotes autophagy.
Guo M, He M, Zhang Y, Liu W, Qi M, Liu Z, Yi G, Deng S, Li Y, Sun X, Zhao L, Chen T, Liu Y., Free PMC Article | 08/22/2023 |
| YWHAE loss of function causes a rare neurodevelopmental disease with brain abnormalities in human and mouse. | YWHAE loss of function causes a rare neurodevelopmental disease with brain abnormalities in human and mouse.
Denommé-Pichon AS, Collins SC, Bruel AL, Mikhaleva A, Wagner C, Vancollie VE, Thomas Q, Chevarin M, Weber M, Prada CE, Overs A, Palomares-Bralo M, Santos-Simarro F, Pacio-Míguez M, Busa T, Legius E, Bacino CA, Rosenfeld JA, Le Guyader G, Egloff M, Le Guillou X, Mencarelli MA, Renieri A, Grosso S, Levy J, Dozières B, Desguerre I, Vitobello A, Duffourd Y, Lelliott CJ, Thauvin-Robinet C, Philippe C, Faivre L, Yalcin B. | 07/24/2023 |
| [NKD1 promotes glucose uptake in colon cancer cells by activating YWHAE transcription]. | [NKD1 promotes glucose uptake in colon cancer cells by activating YWHAE transcription].
Liu Q, Dai Y, Yu H, Shen Y, Deng J, Lu W, Jin J., Free PMC Article | 05/23/2023 |
| Further expansion and confirmation of phenotype in rare loss of YWHAE gene distinct from Miller-Dieker syndrome. | Further expansion and confirmation of phenotype in rare loss of YWHAE gene distinct from Miller-Dieker syndrome.
Baker EK, Brewer CJ, Ferreira L, Schapiro M, Tenney J, Wied HM, Kline-Fath BM, Smolarek TA, Weaver KN, Hopkin RJ., Free PMC Article | 01/21/2023 |
| Genetic variation of YWHAE gene-""Switch"" of disease control.", trans "YWHAE--"""". | Genetic variation of YWHAE gene-"Switch" of disease control.
Jin X, Dai M, Zhou Y., Free PMC Article | 05/21/2022 |
| 14-3-3 epsilon is an intracellular component of TNFR2 receptor complex and its activation protects against osteoarthritis. | 14-3-3 epsilon is an intracellular component of TNFR2 receptor complex and its activation protects against osteoarthritis.
Fu W, Hettinghouse A, Chen Y, Hu W, Ding X, Chen M, Ding Y, Mundra J, Song W, Liu R, Yi YS, Attur M, Samuels J, Strauss E, Leucht P, Schwarzkopf R, Liu CJ., Free PMC Article | 12/11/2021 |
| Genetic vulnerabilities upon inhibition of DNA damage response. | Genetic vulnerabilities upon inhibition of DNA damage response.
Wang C, Tang M, Chen Z, Nie L, Li S, Xiong Y, Szymonowicz KA, Park JM, Zhang H, Feng X, Huang M, Su D, Hart T, Chen J., Free PMC Article | 10/9/2021 |
| Functional study of 14-3-3 protein epsilon (YWHAE) in keratinocytes: microarray integrating bioinformatics approaches. | Functional study of 14-3-3 protein epsilon (YWHAE) in keratinocytes: microarray integrating bioinformatics approaches.
Yin SJ, Lee JR, Kwak H, Lee BN, Han JW, Hahn MJ, Park YD, Yang JM. | 08/28/2021 |
| Prenatal diagnosis of Miller-Dieker syndrome by chromosomal microarray. | Prenatal diagnosis of Miller-Dieker syndrome by chromosomal microarray.
Shi X, Huang W, Lu J, He W, Liu Q, Wu J. | 08/7/2021 |
| Apoptosis repressor with caspase recruitment domain promotes cell proliferation and phenotypic modulation through 14-3-3epsilon/YAP signaling in vascular smooth muscle cells. | Apoptosis repressor with caspase recruitment domain promotes cell proliferation and phenotypic modulation through 14-3-3ε/YAP signaling in vascular smooth muscle cells.
Liu M, Yu T, Li M, Fang X, Hou B, Liu G, Wang J. | 07/31/2021 |
| Activation of innate immunity by 14-3-3 epsilon, a new potential alarmin in osteoarthritis. | Activation of innate immunity by 14-3-3 ε, a new potential alarmin in osteoarthritis.
Millerand M, Sudre L, Nefla M, Pène F, Rousseau C, Pons A, Ravat A, André-Leroux G, Akira S, Satoh T, Berenbaum F, Jacques C. | 07/31/2021 |
| 17p13.3 microdeletion including YWHAE and CRK genes: towards a clinical characterization. | 17p13.3 microdeletion including YWHAE and CRK genes: towards a clinical characterization.
Romano C, Ferranti S, Mencarelli MA, Longo I, Renieri A, Grosso S. | 06/19/2021 |
| YWHAE/14-3-3epsilon expression impacts the protein load, contributing to proteasome inhibitor sensitivity in multiple myeloma. | YWHAE/14-3-3ε expression impacts the protein load, contributing to proteasome inhibitor sensitivity in multiple myeloma.
Xu Y, Fulciniti M, Samur MK, Ho M, Deng S, Liu L, Wen K, Yu T, Chyra Z, Dereibal S, Zhang L, Yao Y, Chakraborty C, Morelli E, Li N, Lopez MA, Perini T, Mu S, An G, Alonso R, Bianchi G, Tai YT, Anderson KC, Qiu L, Munshi NC., Free PMC Article | 02/27/2021 |
| SARS-CoV-2 dysregulation of PTBP1 and YWHAE/Z gene expression: A primer of neurodegeneration. | SARS-CoV-2 dysregulation of PTBP1 and YWHAE/Z gene expression: A primer of neurodegeneration.
Vavougios GD., Free PMC Article | 12/19/2020 |
| YWHAE promotes proliferation, metastasis, and chemoresistance in breast cancer cells. | YWHAE promotes proliferation, metastasis, and chemoresistance in breast cancer cells.
Yang YF, Lee YC, Wang YY, Wang CH, Hou MF, Yuan SF. | 02/8/2020 |
| Overexpression studies revealed that NF-45 promoted cell growth and invasion and upregulated Rac1/Tiam1 signalling via 14-3-3epsilon protein in ESCC cell lines | NF45 promotes esophageal squamous carcinoma cell invasion by increasing Rac1 activity through 14-3-3ε protein.
Wen-Jian Y, Song T, Jun T, Kai-Ying X, Jian-Jun W, Si-Hua W. | 12/14/2019 |
| Cytochrome c and 14-3-3epsilon interaction blocked 14-3-3epsilon-mediated Apaf-1 inhibition. | Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition.
Elena-Real CA, Díaz-Quintana A, González-Arzola K, Velázquez-Campoy A, Orzáez M, López-Rivas A, Gil-Caballero S, De la Rosa MÁ, Díaz-Moreno I., Free PMC Article | 12/7/2019 |
| The results in this report demonstrate that 14-3-3 epsilon and 14-3-3 gamma form a complex with Centrin2 and that the binding site is located in the N-terminal EF hand in Centrin2, EF1. | 14-3-3 proteins mediate the localization of Centrin2 to centrosome.
Bose A, Dalal SN. | 11/30/2019 |
| here we present the first detailed clinical description of a patient with deletion of YWHAE alone, allowing a more accurate characterization of the pathogenicity of YWHAE haploinsufficiency. The patient reported here demonstrated brain abnormalities, learning disabilities, and seizures supporting the role of YWHAE in these features. | Disruption of YWHAE gene at 17p13.3 causes learning disabilities and brain abnormalities.
Noor A, Bogatan S, Watkins N, Meschino WS, Stavropoulos DJ. | 08/3/2019 |
| 14-3-3-NUTM2 gene fusion dysregulates mitogen-activated protein kinase signaling, promoting cell migration in clear cell sarcoma of the kidney. | Dysregulated mitogen-activated protein kinase signalling as an oncogenic basis for clear cell sarcoma of the kidney.
Kenny C, McDonagh N, Lazaro A, O'Meara E, Klinger R, O'Connor D, Roche F, Hokamp K, O'Sullivan MJ. | 07/20/2019 |
| YWHAE is a new cellular partner of Helicobacter pylori CagA. CagA enhances YWHAE-mediated transactivation of NF-kappaB. | YWHAE is a novel interaction partner of Helicobacter pylori CagA.
Zhang X, Zeng B, Wen C, Zheng S, Chen H, She F. | 07/20/2019 |