LncRNA CARD8-AS1 suppresses lung adenocarcinoma progression by enhancing TRIM25-mediated ubiquitination of TXNRD1. | LncRNA CARD8-AS1 suppresses lung adenocarcinoma progression by enhancing TRIM25-mediated ubiquitination of TXNRD1. Pan C, Wang Q, Wang H, Deng X, Chen L, Li Z. | 05/28/2024 |
Suppression of ITPKB degradation by Trim25 confers TMZ resistance in glioblastoma through ROS homeostasis. | Suppression of ITPKB degradation by Trim25 confers TMZ resistance in glioblastoma through ROS homeostasis. Yan Y, Zhou S, Chen X, Yi Q, Feng S, Zhao Z, Liu Y, Liang Q, Xu Z, Li Z, Sun L., Free PMC Article | 03/6/2024 |
TRIM25 promotes glioblastoma cell growth and invasion via regulation of the PRMT1/c-MYC pathway by targeting the splicing factor NONO. | TRIM25 promotes glioblastoma cell growth and invasion via regulation of the PRMT1/c-MYC pathway by targeting the splicing factor NONO. Chen Y, Xu X, Ding K, Tang T, Cai F, Zhang H, Chen Z, Qi Y, Fu Z, Zhu G, Dou Z, Xu J, Chen G, Wu Q, Ji J, Zhang J., Free PMC Article | 02/6/2024 |
TRIM25 inhibition attenuates inflammation, senescence, and oxidative stress in microvascular endothelial cells induced by hyperglycemia. | TRIM25 inhibition attenuates inflammation, senescence, and oxidative stress in microvascular endothelial cells induced by hyperglycemia. Sun D, Li S, Chen S, Zhang S, Gu Q, Shen Y, Wei F, Wang N. | 02/2/2024 |
Degradation of AZGP1 suppresses the progression of breast cancer cells via TRIM25. | Degradation of AZGP1 suppresses the progression of breast cancer cells via TRIM25. Qin H, Yuan Y, Yuan M, Wang H, Yang Y. | 01/11/2024 |
TRIM25 dictates selective miRNA loading into extracellular vesicles during inflammation. | TRIM25 dictates selective miRNA loading into extracellular vesicles during inflammation. King KE, Ghosh P, Wozniak AL., Free PMC Article | 01/3/2024 |
LINC00955 suppresses colorectal cancer growth by acting as a molecular scaffold of TRIM25 and Sp1 to Inhibit DNMT3B-mediated methylation of the PHIP promoter. | LINC00955 suppresses colorectal cancer growth by acting as a molecular scaffold of TRIM25 and Sp1 to Inhibit DNMT3B-mediated methylation of the PHIP promoter. Ren G, Li H, Hong D, Hu F, Jin R, Wu S, Sun W, Jin H, Zhao L, Zhang X, Liu D, Huang C, Huang H., Free PMC Article | 10/2/2023 |
The role of TRIM25 in the occurrence and development of cancers and inflammatory diseases. | The role of TRIM25 in the occurrence and development of cancers and inflammatory diseases. Rahimi-Tesiye M, Zaersabet M, Salehiyeh S, Jafari SZ. | 09/11/2023 |
TRIM25 Suppresses Rabies Virus Fixed HEP-Flury Strain Production by Activating RIG-1-Mediated Type I Interferons. | TRIM25 Suppresses Rabies Virus Fixed HEP-Flury Strain Production by Activating RIG-1-Mediated Type I Interferons. Zhang B, Cai T, He H, Huang X, Luo Y, Huang S, Luo J, Guo X., Free PMC Article | 08/30/2023 |
TRIM25-mediated ubiquitination of G3BP1 regulates the proliferation and migration of human neuroblastoma cells. | TRIM25-mediated ubiquitination of G3BP1 regulates the proliferation and migration of human neuroblastoma cells. Yang Y, Luo Y, Yang C, Hu R, Qin X, Li C. | 08/22/2023 |
TRIM25 mutation (p.C168*), coding for an E3 ubiquitin ligase, is a cause of early-onset autosomal dominant dementia with amyloid load and parkinsonism. | TRIM25 mutation (p.C168*), coding for an E3 ubiquitin ligase, is a cause of early-onset autosomal dominant dementia with amyloid load and parkinsonism. Gómez-Tortosa E, Baradaran-Heravi Y, Dillen L, Choudhury NR, Agüero Rabes P, Pérez-Pérez J, Kocoglu C, Sainz MJ, Ruiz González A, Téllez R, Cremades-Jimeno L, Cárdaba B, EU EOD Consortium, Van Broeckhoven C, Michlewski G, van der Zee J. | 07/27/2023 |
TRIM25 promotes temozolomide resistance in glioma by regulating oxidative stress and ferroptotic cell death via the ubiquitination of keap1. | TRIM25 promotes temozolomide resistance in glioma by regulating oxidative stress and ferroptotic cell death via the ubiquitination of keap1. Wei J, Wang L, Zhang Y, Sun T, Zhang C, Hu Z, Zhou L, Liu X, Wan J, Ma L. | 06/30/2023 |
Hepatitis B virus X protein promotes MAN1B1 expression by enhancing stability of GRP78 via TRIM25 to facilitate hepatocarcinogenesis. | Hepatitis B virus X protein promotes MAN1B1 expression by enhancing stability of GRP78 via TRIM25 to facilitate hepatocarcinogenesis. You H, Zhang N, Yu T, Ma L, Li Q, Wang X, Yuan D, Kong D, Liu X, Hu W, Liu D, Kong F, Zheng K, Tang R., Free PMC Article | 03/15/2023 |
The E3 Ligase TRIM25 Impairs Apoptotic Cell Death in Colon Carcinoma Cells via Destabilization of Caspase-7 mRNA: A Possible Role of hnRNPH1. | The E3 Ligase TRIM25 Impairs Apoptotic Cell Death in Colon Carcinoma Cells via Destabilization of Caspase-7 mRNA: A Possible Role of hnRNPH1. Nasrullah U, Stanke K, Recknagel V, Bozkurt S, Wurzel P, Gauer S, Imre G, Münch C, Pfeilschifter J, Eberhardt W., Free PMC Article | 01/21/2023 |
TRIM25 inhibits influenza A virus infection, destabilizes viral mRNA, but is redundant for activating the RIG-I pathway. | TRIM25 inhibits influenza A virus infection, destabilizes viral mRNA, but is redundant for activating the RIG-I pathway. Choudhury NR, Trus I, Heikel G, Wolczyk M, Szymanski J, Bolembach A, Dos Santos Pinto RM, Smith N, Trubitsyna M, Gaunt E, Digard P, Michlewski G., Free PMC Article | 12/17/2022 |
Tripartite motif-containing 25 facilitates immunosuppression and inhibits apoptosis of glioma via activating NF-kappaB. | Tripartite motif-containing 25 facilitates immunosuppression and inhibits apoptosis of glioma via activating NF-κB. Ge MX, Shi YK, Liu D., Free PMC Article | 10/15/2022 |
RITA1 drives the growth of bladder cancer cells by recruiting TRIM25 to facilitate the proteasomal degradation of RBPJ. | RITA1 drives the growth of bladder cancer cells by recruiting TRIM25 to facilitate the proteasomal degradation of RBPJ. Tang H, Li X, Jiang L, Liu Z, Chen L, Chen J, Deng M, Zhou F, Zheng X, Liu Z., Free PMC Article | 09/24/2022 |
Human metapneumovirus M2-2 protein inhibits RIG-I signaling by preventing TRIM25-mediated RIG-I ubiquitination. | Human metapneumovirus M2-2 protein inhibits RIG-I signaling by preventing TRIM25-mediated RIG-I ubiquitination. Tanaka Y, Morita N, Kitagawa Y, Gotoh B, Komatsu T., Free PMC Article | 09/17/2022 |
Identification and Validation of TRIM25 as a Glucose Metabolism Regulator in Prostate Cancer. | Identification and Validation of TRIM25 as a Glucose Metabolism Regulator in Prostate Cancer. Li C, Dou P, Lu X, Guan P, Lin Z, Zhou Y, Lu X, Lin X, Xu G., Free PMC Article | 09/3/2022 |
Efp promotes growth of triple-negative breast cancer cells. | Efp promotes growth of triple-negative breast cancer cells. Sato W, Ikeda K, Gotoh N, Inoue S, Horie K. | 08/27/2022 |
IFN-I inducible miR-3614-5p targets ADAR1 isoforms and fine tunes innate immune activation. | IFN-I inducible miR-3614-5p targets ADAR1 isoforms and fine tunes innate immune activation. Vuillier F, Li Z, Black I, Cruciani M, Rubino E, Michel F, Pellegrini S., Free PMC Article | 08/13/2022 |
Long noncoding RNA AVAN promotes antiviral innate immunity by interacting with TRIM25 and enhancing the transcription of FOXO3a. | Long noncoding RNA AVAN promotes antiviral innate immunity by interacting with TRIM25 and enhancing the transcription of FOXO3a. Lai C, Liu L, Liu Q, Wang K, Cheng S, Zhao L, Xia M, Wang C, Duan Y, Zhang L, Liu Z, Luo J, Wang X, Chen R, Yang P., Free PMC Article | 03/26/2022 |
E3 ligase TRIM25 ubiquitinates RIP3 to inhibit TNF induced cell necrosis. | E3 ligase TRIM25 ubiquitinates RIP3 to inhibit TNF induced cell necrosis. Mei P, Xie F, Pan J, Wang S, Gao W, Ge R, Gao B, Gao S, Chen X, Wang Y, Wu J, Ding C, Li J., Free PMC Article | 03/26/2022 |
ATAD2 drives colorectal cancer progression by regulating TRIM25 expression via a positive feedback loop with E2F transcriptional factors. | ATAD2 drives colorectal cancer progression by regulating TRIM25 expression via a positive feedback loop with E2F transcriptional factors. Tong Y, Li J, Peng M, Qian Q, Shi W, Chen Z, Liu B. | 03/19/2022 |
Ectopic Expression of TRIM25 Restores RIG-I Expression and IFN Production Reduced by Multiple Enteroviruses 3C(pro). | Ectopic Expression of TRIM25 Restores RIG-I Expression and IFN Production Reduced by Multiple Enteroviruses 3C(pro). Xiao H, Li J, Yang X, Li Z, Wang Y, Rui Y, Liu B, Zhang W., Free PMC Article | 01/1/2022 |