| Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals. | Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals.
Herr LA, Fiala GJ, Sagar, Schaffer AM, Hummel JF, Zintchenko M, Raute K, Velasco Cárdenas RM, Heizmann B, Ebert K, Fehrenbach K, Janowska I, Chan S, Tanriver Y, Minguet S, Schamel WW., Free PMC Article | 03/20/2024 |
| Kidins220 sets the threshold for survival of neural stem cells and progenitors to sustain adult neurogenesis. | Kidins220 sets the threshold for survival of neural stem cells and progenitors to sustain adult neurogenesis.
Del Puerto A, Lopez-Fonseca C, Simón-García A, Martí-Prado B, Barrios-Muñoz AL, Pose-Utrilla J, López-Menéndez C, Alcover-Sanchez B, Cesca F, Schiavo G, Campanero MR, Fariñas I, Iglesias T, Porlan E., Free PMC Article | 08/9/2023 |
| ARMS/Kidins220 regulates nociception by controlling brain-derived neurotrophic factor secretion. | ARMS/Kidins220 regulates nociception by controlling brain-derived neurotrophic factor secretion.
Sánchez-Sánchez J, Vicente-García C, Cañada-García D, Martín-Zanca D, Arévalo JC. | 02/14/2023 |
| Kidins220 deficiency causes ventriculomegaly via SNX27-retromer-dependent AQP4 degradation. | Kidins220 deficiency causes ventriculomegaly via SNX27-retromer-dependent AQP4 degradation.
Del Puerto A, Pose-Utrilla J, Simón-García A, López-Menéndez C, Jiménez AJ, Porlan E, Pajuelo LSM, Cano-García G, Martí-Prado B, Sebastián-Serrano Á, Sánchez-Carralero MP, Cesca F, Schiavo G, Ferrer I, Fariñas I, Campanero MR, Iglesias T., Free PMC Article | 03/19/2022 |
| A developmental stage- and Kidins220-dependent switch in astrocyte responsiveness to brain-derived neurotrophic factor. | A developmental stage- and Kidins220-dependent switch in astrocyte responsiveness to brain-derived neurotrophic factor.
Jaudon F, Albini M, Ferroni S, Benfenati F, Cesca F. | 12/11/2021 |
| Kidins220/ARMS controls astrocyte calcium signaling and neuron-astrocyte communication. | Kidins220/ARMS controls astrocyte calcium signaling and neuron-astrocyte communication.
Jaudon F, Chiacchiaretta M, Albini M, Ferroni S, Benfenati F, Cesca F., Free PMC Article | 07/3/2021 |
| Kidins220 has a prominent role in tumor development by participating in a complex signaling pathways. (Review) | Kidins220 and tumour development: Insights into a complexity of cross-talk among signalling pathways (Review).
Cai S, Cai J, Jiang WG, Ye L., Free PMC Article | 05/19/2018 |
| Kidins220 binds to the B cell antigen receptor and regulates B cell development and activation. | Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation.
Fiala GJ, Janowska I, Prutek F, Hobeika E, Satapathy A, Sprenger A, Plum T, Seidl M, Dengjel J, Reth M, Cesca F, Brummer T, Minguet S, Schamel WW., Free PMC Article | 04/30/2016 |
| the existence of novel Kidins220/ARMS splice isoforms with unique properties | Novel Kidins220/ARMS Splice Isoforms: Potential Specific Regulators of Neuronal and Cardiovascular Development.
Schmieg N, Thomas C, Yabe A, Lynch DS, Iglesias T, Chakravarty P, Schiavo G., Free PMC Article | 04/30/2016 |
| The scaffold protein Kidins220 associates with brain voltage-gated sodium channels and modulates their activity. | Functional Interaction between the Scaffold Protein Kidins220/ARMS and Neuronal Voltage-Gated Na+ Channels.
Cesca F, Satapathy A, Ferrea E, Nieus T, Benfenati F, Scholz-Starke J., Free PMC Article | 10/17/2015 |
| Results suggest a new role of ARMS/Kidins220 as a signaling platform to regulate tumor cell proliferation in response to the extracellular stimuli. | Ankyrin repeat-rich membrane spanning (ARMS)/Kidins220 scaffold protein regulates neuroblastoma cell proliferation through p21.
Jung H, Shin JH, Park YS, Chang MS., Free PMC Article | 08/29/2015 |
| Kidins220/ARMS is expressed in the spleen and peripheral blood of normal BALB/c mice and may participate in the immuno-inflammation of asthma through the nerve growth factor-mediated signaling pathway. | Expression of neuronal protein Kidins220/ARMS in the spleen and peripheral blood of mice following airway allergen challenge.
Li N, Dong X, Yang C, Liu Y, Ni X. | 05/31/2014 |
| results collectively suggest that ARMS/Kidins220 is a key player in organizing the signaling complex to transduce the extracellular stimuli to cellular responses during dendrite development. | Ankyrin repeat-rich membrane spanning protein (kidins220) is required for neurotrophin and ephrin receptor-dependent dendrite development.
Chen Y, Fu WY, Ip JP, Ye T, Fu AK, Chao MV, Ip NY., Free PMC Article | 09/29/2012 |
| Neurons with altered Kidins220 expression, the constitutive absence of Kidins220 did not affect basal synaptic transmission either in excitatory or inhibitory synapses. | Kidins220/ARMS is a novel modulator of short-term synaptic plasticity in hippocampal GABAergic neurons.
Scholz-Starke J, Cesca F, Schiavo G, Benfenati F, Baldelli P., Free PMC Article | 09/22/2012 |
| Kidins220 mediates the integration of several growth factor receptor pathways during development | Kidins220/ARMS mediates the integration of the neurotrophin and VEGF pathways in the vascular and nervous systems.
Cesca F, Yabe A, Spencer-Dene B, Scholz-Starke J, Medrihan L, Maden CH, Gerhardt H, Orriss IR, Baldelli P, Al-Qatari M, Koltzenburg M, Adams RH, Benfenati F, Schiavo G., Free PMC Article | 05/5/2012 |
| Kidins220 has a critical function in the postnatal brain. | Kidins220/ARMS is an essential modulator of cardiovascular and nervous system development.
Cesca F, Yabe A, Spencer-Dene B, Arrigoni A, Al-Qatari M, Henderson D, Phillips H, Koltzenburg M, Benfenati F, Schiavo G., Free PMC Article | 04/14/2012 |
| Mice heterozygous for kidins220 shows defects in entorhinal cortex and frontal cortex and in water maze learning. Females, not males were affected. | A selective role for ARMS/Kidins220 scaffold protein in spatial memory and trophic support of entorhinal and frontal cortical neurons.
Duffy AM, Schaner MJ, Wu SH, Staniszewski A, Kumar A, Arévalo JC, Arancio O, Chao MV, Scharfman HE., Free PMC Article | 08/6/2011 |
| This study suggested that ARMS/Kidins220 is important for the growth of dendritic arbors and spine stability during an activity- and BDNF-dependent period of development. | Ankyrin Repeat-rich Membrane Spanning/Kidins220 protein regulates dendritic branching and spine stability in vivo.
Wu SH, Arévalo JC, Sarti F, Tessarollo L, Gan WB, Chao MV., Free PMC Article | 05/9/2011 |
| overexpressed on the bronchoalveolar lavage fluid cells of asthmatic mice | NGF/TrkA-mediated Kidins220/ARMS signaling activated in the allergic airway challenge in mice.
Ni X, Li X, Fang X, Li N, Cui W, Zhang B. | 02/26/2011 |
| the levels of ARMS/Kidins220 can be regulated by neuronal activity and calpain action to influence synaptic function. | The ankyrin repeat-rich membrane spanning (ARMS)/Kidins220 scaffold protein is regulated by activity-dependent calpain proteolysis and modulates synaptic plasticity.
Wu SH, Arévalo JC, Neubrand VE, Zhang H, Arancio O, Chao MV., Free PMC Article | 01/29/2011 |
| These results provide evidence that modulation of ARMS/Kidins220 levels can regulate basal synaptic strength in a specific manner in hippocampal neurons. | The ARMS/Kidins220 scaffold protein modulates synaptic transmission.
Arévalo JC, Wu SH, Takahashi T, Zhang H, Yu T, Yano H, Milner TA, Tessarollo L, Ninan I, Arancio O, Chao MV., Free PMC Article | 01/1/2011 |
| Kidins220/ARMS is a key modulator of the activity of microtubule-regulating proteins known to actively regulate neuronal morphogenesis and suggest a mechanism by which it contributes to control neuronal development. | Kidins220/ARMS modulates the activity of microtubule-regulating proteins and controls neuronal polarity and development.
Higuero AM, Sánchez-Ruiloba L, Doglio LE, Portillo F, Abad-Rodríguez J, Dotti CG, Iglesias T., Free PMC Article | 02/1/2010 |