| Upregulation of dual-specificity phosphatase-26 is required for transforming growth factor beta1(TGFbeta1)-induced Epithelial-mesenchymal transition in A549 and PANC1 cells. | Upregulation of dual-specificity phosphatase-26 is required for transforming growth factor β1(TGFβ1)-induced Epithelial-mesenchymal transition in A549 and PANC1 cells.
Guler S, Zik B, Yalcin A. | 11/5/2022 |
| Falnidamol and cisplatin combinational treatment inhibits non-small cell lung cancer (NSCLC) by targeting DUSP26-mediated signal pathways. | Falnidamol and cisplatin combinational treatment inhibits non-small cell lung cancer (NSCLC) by targeting DUSP26-mediated signal pathways.
Cui Z, Li D, Zhao J, Chen K. | 04/16/2022 |
| Dusp26 phosphatase regulates mitochondrial respiration and oxidative stress and protects neuronal cell death. | Dusp26 phosphatase regulates mitochondrial respiration and oxidative stress and protects neuronal cell death.
Eroglu B, Jin X, Deane S, Öztürk B, Ross OA, Moskophidis D, Mivechi NF., Free PMC Article | 03/26/2022 |
| DUSP26 induces aortic valve calcification by antagonizing MDM2-mediated ubiquitination of DPP4 in human valvular interstitial cells. | DUSP26 induces aortic valve calcification by antagonizing MDM2-mediated ubiquitination of DPP4 in human valvular interstitial cells.
Wang Y, Han D, Zhou T, Chen C, Cao H, Zhang JZ, Ma N, Liu C, Song M, Shi J, Jin X, Cao F, Dong N. | 09/11/2021 |
| A Review of DUSP26: Structure, Regulation and Relevance in Human Disease. | A Review of DUSP26: Structure, Regulation and Relevance in Human Disease.
Thompson EM, Stoker AW., Free PMC Article | 09/11/2021 |
| DUSP26 might be a promising therapeutic target for developing effective treatments against Diabetic nephropathy progression. | DUSP26 regulates podocyte oxidative stress and fibrosis in a mouse model with diabetic nephropathy through the mediation of ROS.
Huang F, Sheng XX, Zhang HJ. | 07/4/2020 |
| overexpression in liver cell line attenuated lipid deposition and inflammation induced by palmitate | Dual-Specificity Phosphatase 26 Protects Against Nonalcoholic Fatty Liver Disease in Mice Through Transforming Growth Factor Beta-Activated Kinase 1 Suppression.
Ye P, Liu J, Xu W, Liu D, Ding X, Le S, Zhang H, Chen S, Chen M, Xia J., Free PMC Article | 06/20/2020 |
| Enhanced expression of DUSP26 was observed in the hippocampus of Alzheimer's disease patients. | Dual-specificity phosphatase 26 (DUSP26) stimulates Aβ42 generation by promoting amyloid precursor protein axonal transport during hypoxia.
Jung S, Nah J, Han J, Choi SG, Kim H, Park J, Pyo HK, Jung YK. | 06/10/2017 |
| results suggest that AK2 is an associated activator of DUSP26 and suppresses cell proliferation by FADD dephosphorylation, postulating AK2 as a negative regulator of tumour growth. | The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth.
Kim H, Lee HJ, Oh Y, Choi SG, Hong SH, Kim HJ, Lee SY, Choi JW, Su Hwang D, Kim KS, Kim HJ, Zhang J, Youn HJ, Noh DY, Jung YK., Free PMC Article | 11/7/2015 |
| The study reports the 1.68 A crystal structure of a catalytically inactive mutant (Cys152Ser) of DUSP26 lacking the first 60 N-terminal residues (DeltaN60-C/S-DUSP26). | Atomic structure of dual-specificity phosphatase 26, a novel p53 phosphatase.
Lokareddy RK, Bhardwaj A, Cingolani G., Free PMC Article | 03/30/2013 |
| Observational study of gene-disease association. (HuGE Navigator) | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ., Free PMC Article | 12/5/2010 |
| DUSP26 may function as a tumour suppressor in particular cancers. | DUSP26 negatively affects the proliferation of epithelial cells, an effect not mediated by dephosphorylation of MAPKs.
Patterson KI, Brummer T, Daly RJ, O'Brien PM. | 10/30/2010 |
| DUSP26 functions as a p53 phosphatase | Dual-specificity phosphatase 26 is a novel p53 phosphatase and inhibits p53 tumor suppressor functions in human neuroblastoma.
Shang X, Vasudevan SA, Yu Y, Ge N, Ludwig AD, Wesson CL, Wang K, Burlingame SM, Zhao YJ, Rao PH, Lu X, Russell HV, Okcu MF, Hicks MJ, Shohet JM, Donehower LA, Nuchtern JG, Yang J., Free PMC Article | 10/23/2010 |
| Downregulation of Dusp26 may contribute to malignant phenotypes of glioma. | Protein phosphatase Dusp26 associates with KIF3 motor and promotes N-cadherin-mediated cell-cell adhesion.
Tanuma N, Nomura M, Ikeda M, Kasugai I, Tsubaki Y, Takagaki K, Kawamura T, Yamashita Y, Sato I, Sato M, Katakura R, Kikuchi K, Shima H. | 01/21/2010 |
| DUSP26 effectively dephosphorylates p38 and has a little effect on extracellular signal-regulated kinase in anaplastic thyroid cancer. | A novel amplification target, DUSP26, promotes anaplastic thyroid cancer cell growth by inhibiting p38 MAPK activity.
Yu W, Imoto I, Inoue J, Onda M, Emi M, Inazawa J. | 01/21/2010 |