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    ZC3H12A zinc finger CCCH-type containing 12A [ Homo sapiens (human) ]

    Gene ID: 80149, updated on 3-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    MCPIP1 Inhibits Hepatic Stellate Cell Activation in Autocrine and Paracrine Manners, Preventing Liver Fibrosis.

    MCPIP1 Inhibits Hepatic Stellate Cell Activation in Autocrine and Paracrine Manners, Preventing Liver Fibrosis.
    Pydyn N, Ferenc A, Trzos K, Pospiech E, Wilamowski M, Mucha O, Major P, Kadluczka J, Rodrigues PM, Banales JM, Herranz JM, Avila MA, Hutsch T, Malczak P, Radkowiak D, Budzynski A, Jura J, Kotlinowski J., Free PMC Article

    05/28/2024
    MCPIP-1 knockdown enhances endothelial colony-forming cell angiogenesis via the TFRC/AKT/mTOR signaling pathway in the ischemic penumbra of MCAO mice.

    MCPIP-1 knockdown enhances endothelial colony-forming cell angiogenesis via the TFRC/AKT/mTOR signaling pathway in the ischemic penumbra of MCAO mice.
    Zou X, Xie Y, Zhang Z, Feng Z, Han J, Ouyang Q, Hua S, Huang S, Li C, Liu Z, Cai Y, Zou Y, Tang Y, Chen H, Jiang X.

    11/6/2023
    Regnase-1 downregulation promotes pancreatic cancer through myeloid-derived suppressor cell-mediated evasion of anticancer immunity.

    Regnase-1 downregulation promotes pancreatic cancer through myeloid-derived suppressor cell-mediated evasion of anticancer immunity.
    Okabe J, Kodama T, Sato Y, Shigeno S, Matsumae T, Daiku K, Sato K, Yoshioka T, Shigekawa M, Higashiguchi M, Kobayashi S, Hikita H, Tatsumi T, Okamoto T, Satoh T, Eguchi H, Akira S, Takehara T., Free PMC Article

    10/11/2023
    Localization and expression profiles of gingival monocyte chemoattractant protein-1-induced protein-1 (MCPIP-1) and mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT-1).

    Localization and expression profiles of gingival monocyte chemoattractant protein-1-induced protein-1 (MCPIP-1) and mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT-1).
    Yu L, Firatli Y, Elmanfi S, Gürsoy M, Özdemir Kabalak M, Kasnak G, Pussinen P, Bikker FJ, Caglayan F, Firatli E, Gürsoy UK., Free PMC Article

    05/12/2023
    Combined disruption of T cell inflammatory regulators Regnase-1 and Roquin-1 enhances antitumor activity of engineered human T cells.

    Combined disruption of T cell inflammatory regulators Regnase-1 and Roquin-1 enhances antitumor activity of engineered human T cells.
    Mai D, Johnson O, Reff J, Fan TJ, Scholler J, Sheppard NC, June CH., Free PMC Article

    03/27/2023
    MCPIP1 Suppresses the NF-kappaB Signaling Pathway Through Negative Regulation of K63-Linked Ubiquitylation of TRAF6 in Colorectal Cancer.

    MCPIP1 Suppresses the NF-κB Signaling Pathway Through Negative Regulation of K63-Linked Ubiquitylation of TRAF6 in Colorectal Cancer.
    Ye W, Cui Y, Rong J, Huang W, Zheng Z, Li A, Li Y.

    01/21/2023
    MCPIP1 alleviates inflammatory response through inducing autophagy in Aspergillus fumigatus keratitis.

    MCPIP1 alleviates inflammatory response through inducing autophagy in Aspergillus fumigatus keratitis.
    Han F, Shen L, Ma H, Wang L, Guo H, Wu X.

    12/10/2022
    MCP-Induced Protein 1 Participates in Macrophage-Dependent Endotoxin Tolerance.

    MCP-Induced Protein 1 Participates in Macrophage-Dependent Endotoxin Tolerance.
    Wadowska M, Dobosz E, Golda A, Bryzek D, Lech M, Fu M, Koziel J.

    10/8/2022
    Resistance to tyrosine kinase inhibitors promotes renal cancer progression through MCPIP1 tumor-suppressor downregulation and c-Met activation.

    Resistance to tyrosine kinase inhibitors promotes renal cancer progression through MCPIP1 tumor-suppressor downregulation and c-Met activation.
    Marona P, Górka J, Kwapisz O, Jura J, Rys J, Hoffman RM, Miekus K., Free PMC Article

    10/8/2022
    MCPIP1 promotes cell proliferation, migration and angiogenesis of glioma via VEGFA-mediated ERK pathway.

    MCPIP1 promotes cell proliferation, migration and angiogenesis of glioma via VEGFA-mediated ERK pathway.
    Wang R, Sun S, Wang Z, Xu X, Jiang T, Liu H, Li X, Ren Z.

    07/30/2022
    MCPIP1 regulates focal adhesion kinase and Rho GTPase-dependent migration in clear cell renal cell carcinoma.

    MCPIP1 regulates focal adhesion kinase and Rho GTPase-dependent migration in clear cell renal cell carcinoma.
    Gorka J, Marona P, Kwapisz O, Rys J, Jura J, Miekus K.

    04/23/2022
    Dynamic Regulation of the Nexus Between Stress Granules, Roquin, and Regnase-1 Underlies the Molecular Pathogenesis of Warfare Vesicants.

    Dynamic Regulation of the Nexus Between Stress Granules, Roquin, and Regnase-1 Underlies the Molecular Pathogenesis of Warfare Vesicants.
    Srivastava RK, Mishra B, Muzaffar S, Gorbatyuk MS, Agarwal A, Mukhtar MS, Athar M., Free PMC Article

    03/5/2022
    MCPIP1 inhibits Wnt/beta-catenin signaling pathway activity and modulates epithelial-mesenchymal transition during clear cell renal cell carcinoma progression by targeting miRNAs.

    MCPIP1 inhibits Wnt/β-catenin signaling pathway activity and modulates epithelial-mesenchymal transition during clear cell renal cell carcinoma progression by targeting miRNAs.
    Gorka J, Marona P, Kwapisz O, Waligórska A, Pospiech E, Dobrucki JW, Rys J, Jura J, Miekus K., Free PMC Article

    01/8/2022
    MCPIP1 ribonuclease can bind and cleave AURKA mRNA in MYCN-amplified neuroblastoma cells.

    MCPIP1 ribonuclease can bind and cleave AURKA mRNA in MYCN-amplified neuroblastoma cells.
    Nowak I, Boratyn E, Student S, Bernhart SF, Fallmann J, Durbas M, Stadler PF, Rokita H., Free PMC Article

    12/4/2021
    MCPIP1 is a novel link between diabetogenic conditions and impaired insulin secretory capacity.

    MCPIP1 is a novel link between diabetogenic conditions and impaired insulin secretory capacity.
    Tyka K, Jörns A, Dunst A, Tang Y, Bryde TH, Mehmeti I, Walentinsson A, Marselli L, Cnop M, Tyrberg B, Marzec MT, Gurgul-Convey E.

    11/13/2021
    Monocyte Chemotactic Protein-Induced Protein 1 (MCPIP-1): A Key Player of Host Defense and Immune Regulation.

    Monocyte Chemotactic Protein-Induced Protein 1 (MCPIP-1): A Key Player of Host Defense and Immune Regulation.
    Jin Z, Zheng E, Sareli C, Kolattukudy PE, Niu J., Free PMC Article

    11/6/2021
    MCPIP1-mediated NFIC alternative splicing inhibits proliferation of triple-negative breast cancer via cyclin D1-Rb-E2F1 axis.

    MCPIP1-mediated NFIC alternative splicing inhibits proliferation of triple-negative breast cancer via cyclin D1-Rb-E2F1 axis.
    Chen F, Wang Q, Yu X, Yang N, Wang Y, Zeng Y, Zheng Z, Zhou F, Zhou Y., Free PMC Article

    09/25/2021
    MCPIP1/Regnase-1 Expression in Keratinocytes of Patients with Hidradenitis Suppurativa: Preliminary Results.

    MCPIP1/Regnase-1 Expression in Keratinocytes of Patients with Hidradenitis Suppurativa: Preliminary Results.
    Krajewski PK, Szukała W, Lichawska-Cieślar A, Matusiak Ł, Jura J, Szepietowski JC., Free PMC Article

    08/7/2021
    MCPIP1 overexpression in human neuroblastoma cell lines causes cell-cycle arrest by G1/S checkpoint block.

    MCPIP1 overexpression in human neuroblastoma cell lines causes cell-cycle arrest by G1/S checkpoint block.
    Boratyn E, Nowak I, Karnas E, Ryszawy D, Wnuk D, Polus A, Durbas M, Horwacik I, Rokita H.

    07/10/2021
    Increased expression of CDKN1A/p21 in HIV-1 controllers is correlated with upregulation of ZC3H12A/MCPIP1.

    Increased expression of CDKN1A/p21 in HIV-1 controllers is correlated with upregulation of ZC3H12A/MCPIP1.
    de Azevedo SSD, Ribeiro-Alves M, Côrtes FH, Delatorre E, Spangenberg L, Naya H, Seito LN, Hoagland B, Grinsztejn B, Veloso VG, Morgado MG, Souza TML, Bello G., Free PMC Article

    06/26/2021
    Multifunctional RNase MCPIP1 and its Role in Cardiovascular Diseases.

    Multifunctional RNase MCPIP1 and its Role in Cardiovascular Diseases.
    Yan B, Guo Y, Gui Y, Jiang ZS, Zheng XL.

    06/19/2021
    Monocyte chemoattractant protein-induced protein 1 directly degrades viral miRNAs with a specific motif and inhibits KSHV infection.

    Monocyte chemoattractant protein-induced protein 1 directly degrades viral miRNAs with a specific motif and inhibits KSHV infection.
    Kook I, Ziegelbauer JM., Free PMC Article

    06/19/2021
    Elevated linc00936 or silenced microRNA-425-3p inhibits immune escape of gastric cancer cells via elevation of ZC3H12A.

    Elevated linc00936 or silenced microRNA-425-3p inhibits immune escape of gastric cancer cells via elevation of ZC3H12A.
    Li H, Zhao C, Zhao H, Liu G, Mao H, Liu Y.

    06/5/2021
    The anti-inflammatory protein MCPIP1 inhibits the development of ccRCC by maintaining high levels of tumour suppressors.

    The anti-inflammatory protein MCPIP1 inhibits the development of ccRCC by maintaining high levels of tumour suppressors.
    Gorka J, Marona P, Kwapisz O, Rys J, Jura J, Miekus K.

    05/22/2021
    MCPIP1 expression positively correlates with melanoma-specific survival of patients, and its overexpression affects vital intracellular pathways of human melanoma cells.

    MCPIP1 expression positively correlates with melanoma-specific survival of patients, and its overexpression affects vital intracellular pathways of human melanoma cells.
    Nowak I, Brożyna AA, Zabłocka M, Student S, Durbas M, Bugara B, Rokita H.

    05/1/2021
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