| circRNA TATA-box binding protein associated factor 15 acts as an oncogene to facilitate bladder cancer progression through targeting miR-502-5p/high mobility group box 3. | circRNA TATA-box binding protein associated factor 15 acts as an oncogene to facilitate bladder cancer progression through targeting miR-502-5p/high mobility group box 3.
Yang H, He P, Luo W, Liu S, Yang Y. | 03/15/2024 |
| TAF15 amyloid filaments in frontotemporal lobar degeneration. | TAF15 amyloid filaments in frontotemporal lobar degeneration.
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B., Free PMC Article | 01/13/2024 |
| m6A-enriched lncRNA LINC00839 promotes tumor progression by enhancing TAF15-mediated transcription of amine oxidase AOC1 in nasopharyngeal carcinoma. | m6A-enriched lncRNA LINC00839 promotes tumor progression by enhancing TAF15-mediated transcription of amine oxidase AOC1 in nasopharyngeal carcinoma.
Zheng WH, Long ZQ, Zheng ZQ, Zhang LL, Liang YL, Li ZX, Lv JW, Kou J, Hong XH, He SW, Xu R, Zhou GQ, Liu N, Ma J, Sun Y, Lin L, Wei D., Free PMC Article | 08/1/2023 |
| TAF15 promotes cell proliferation, migration and invasion of gastric cancer via activation of the RAF1/MEK/ERK signalling pathway. | TAF15 promotes cell proliferation, migration and invasion of gastric cancer via activation of the RAF1/MEK/ERK signalling pathway.
Tang L, Guo C, Li X, Zhang B, Huang L., Free PMC Article | 04/12/2023 |
| CircDNAJC11 interacts with TAF15 to promote breast cancer progression via enhancing MAPK6 expression and activating the MAPK signaling pathway. | CircDNAJC11 interacts with TAF15 to promote breast cancer progression via enhancing MAPK6 expression and activating the MAPK signaling pathway.
Wang B, Chen H, Deng Y, Chen H, Xing L, Guo Y, Wang M, Chen J., Free PMC Article | 03/17/2023 |
| LncRNA LINC00649 recruits TAF15 and enhances MAPK6 expression to promote the development of lung squamous cell carcinoma via activating MAPK signaling pathway. | LncRNA LINC00649 recruits TAF15 and enhances MAPK6 expression to promote the development of lung squamous cell carcinoma via activating MAPK signaling pathway.
Zhu H, Liu Q, Yang X, Ding C, Wang Q, Xiong Y. | 09/3/2022 |
| The SGYS motif of TAF15 prion-like domain is critical to amyloid fibril formation. | The SGYS motif of TAF15 prion-like domain is critical to amyloid fibril formation.
Chen J, Yuan X, Wei P, Wang D, Chen C, Guo Q, Luo SZ, Chen L., Free PMC Article | 07/16/2022 |
| LncRNA GAS5 activates the HIF1A/VEGF pathway by binding to TAF15 to promote wound healing in diabetic foot ulcers. | LncRNA GAS5 activates the HIF1A/VEGF pathway by binding to TAF15 to promote wound healing in diabetic foot ulcers.
Peng WX, He PX, Liu LJ, Zhu T, Zhong YQ, Xiang L, Peng K, Yang JJ, Xiang GD. | 09/4/2021 |
| SCF-Slimb is critical for Glycogen synthase kinase-3beta-mediated suppression of TAF15-induced neurotoxicity in Drosophila. | SCF-Slimb is critical for Glycogen synthase kinase-3β-mediated suppression of TAF15-induced neurotoxicity in Drosophila.
Choi HJ, Joo Cha S, Do HA, Kim HJ, Lee JW, Kim K. | 08/28/2021 |
| LncRNA PITPNA-AS1 boosts the proliferation and migration of lung squamous cell carcinoma cells by recruiting TAF15 to stabilize HMGB3 mRNA. | LncRNA PITPNA-AS1 boosts the proliferation and migration of lung squamous cell carcinoma cells by recruiting TAF15 to stabilize HMGB3 mRNA.
Ren P, Xing L, Hong X, Chang L, Zhang H., Free PMC Article | 05/22/2021 |
| Loci-specific phase separation of FET fusion oncoproteins promotes gene transcription. | Loci-specific phase separation of FET fusion oncoproteins promotes gene transcription.
Zuo L, Zhang G, Massett M, Cheng J, Guo Z, Wang L, Gao Y, Li R, Huang X, Li P, Qi Z., Free PMC Article | 03/20/2021 |
| TRPM2-AS promotes cancer cell proliferation through control of TAF15. | TRPM2-AS promotes cancer cell proliferation through control of TAF15.
Pan L, Li Y, Jin L, Li J, Xu A. | 10/31/2020 |
| NR4A3 fusion proteins trigger an axon guidance switch that marks the difference between EWSR1 and TAF15 translocated extraskeletal myxoid chondrosarcomas cells. | NR4A3 fusion proteins trigger an axon guidance switch that marks the difference between EWSR1 and TAF15 translocated extraskeletal myxoid chondrosarcomas.
Brenca M, Stacchiotti S, Fassetta K, Sbaraglia M, Janjusevic M, Racanelli D, Polano M, Rossi S, Brich S, Dagrada GP, Collini P, Colombo C, Gronchi A, Astolfi A, Indio V, Pantaleo MA, Picci P, Casali PG, Dei Tos AP, Pilotti S, Maestro R., Free PMC Article | 04/18/2020 |
| FUS, EWSR1, TAF15 and MATR3 within the RNAP II/U1 snRNP machinery play distinct roles in the development of amyotrophic lateral sclerosis and spinal muscular atrophy that are more intimately tied to one another than previously thought. | The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex.
Chi B, O'Connell JD, Iocolano AD, Coady JA, Yu Y, Gangopadhyay J, Gygi SP, Reed R., Free PMC Article | 06/29/2019 |
| Results find that the Asp residue in TAF15 YGGDR(S/G)G repeats confers poor binding to PRMT1 indicating that YGGDR(S/G)G repeats may contribute to TAF15 specialization by enabling differential interactions with PRMT1 and reduced overall levels of TAF15 methylation compared with other FET proteins. | Differential interaction of PRMT1 with RGG-boxes of the FET family proteins EWS and TAF15.
Li KKC, Chau BL, Lee KAW., Free PMC Article | 01/12/2019 |
| weak, multivalent interactions between TAF15 fibrils and heptads throughout RNA pol II CTD collectively mediate complex formation. | Lysines in the RNA Polymerase II C-Terminal Domain Contribute to TAF15 Fibril Recruitment.
Janke AM, Seo DH, Rahmanian V, Conicella AE, Mathews KL, Burke KA, Mittal J, Fawzi NL., Free PMC Article | 09/15/2018 |
| In human stem cell-derived motor neurons, the RNA profile associated with concomitant loss of both TAF15 and FUS resembles that observed in the presence of the amyotrophic lateral sclerosis (ALS)-associated mutation FUS R521G, but contrasts with late-stage sporadic ALS patients. | Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses.
Kapeli K, Pratt GA, Vu AQ, Hutt KR, Martinez FJ, Sundararaman B, Batra R, Freese P, Lambert NJ, Huelga SC, Chun SJ, Liang TY, Chang J, Donohue JP, Shiue L, Zhang J, Zhu H, Cambi F, Kasarskis E, Hoon S, Ares M Jr, Burge CB, Ravits J, Rigo F, Yeo GW., Free PMC Article | 09/1/2018 |
| In a cohort of youth at risk for bipolar disorder, pathway analysis showed an enrichment of the glucocorticoid receptor (GR) pathway with the genes MED1, HSPA1L, GTF2A1 and TAF15, which might underlie the previously reported role of stress response in the risk for bipolar disorder in vulnerable populations. | Integrated transcriptome and methylome analysis in youth at high risk for bipolar disorder: a preliminary analysis.
Fries GR, Quevedo J, Zeni CP, Kazimi IF, Zunta-Soares G, Spiker DE, Bowden CL, Walss-Bass C, Soares JC., Free PMC Article | 11/25/2017 |
| Aggregation of FET proteins FUS, EWSR1, and TAF15 mediate a pathological change in amyotrophic lateral sclerosis. (Review) | Aggregation of FET Proteins as a Pathological Change in Amyotrophic Lateral Sclerosis.
Furukawa Y, Tokuda E. | 09/9/2017 |
| Studies provide evidence that FUS/TLS, EWS and TAF15 proteins play a major role in neurodegenerative disorders. (review). | Role of FET proteins in neurodegenerative disorders.
Svetoni F, Frisone P, Paronetto MP., Free PMC Article | 05/13/2017 |
| O-GlcNAc glycosylation stoichiometry of TAF15 | O-GlcNAc glycosylation stoichiometry of the FET protein family: only EWS is glycosylated with a high stoichiometry.
Kamemura K. | 03/11/2017 |
| RNA binding by TAF-15 is dependent upon structural elements in the RNA rather than sequence. | Structural delineation of stem-loop RNA binding by human TAF15 protein.
Kashyap M, Ganguly AK, Bhavesh NS., Free PMC Article | 10/8/2016 |
| our data suggest that TAF15 and TLS/FUS operate within similar but not identical hnRNP M-TET protein complexes to influence the transcriptional or post-transcriptional output of a particular cell type. | Selective interactions of hnRNP M isoforms with the TET proteins TAF15 and TLS/FUS.
Marko M, Leichter M, Patrinou-Georgoula M, Guialis A. | 12/6/2014 |
| Data indicate that distinct differences in proteins becoming Poly(ADP-ribose) PARylated upon various genotoxic insults are observed, exemplified by the PARylation of RNA-processing factors THRAP3 and TAF15 under oxidative stress. | Proteome-wide identification of poly(ADP-Ribosyl)ation targets in different genotoxic stress responses.
Jungmichel S, Rosenthal F, Altmeyer M, Lukas J, Hottiger MO, Nielsen ML. | 01/18/2014 |
| TAF15 depletion inhibits growth & increases apoptosis. Its knockdown affects many genes involved in cell cycle & cell death. Among these, targets of microRNAs generated from the onco-miR-17 locus were overrepresented. | TAF15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through miRNAs.
Ballarino M, Jobert L, Dembélé D, de la Grange P, Auboeuf D, Tora L. | 11/16/2013 |