Potential Role of Moesin in Regulating Mast Cell Secretion. | Potential Role of Moesin in Regulating Mast Cell Secretion. Theoharides TC, Kempuraj D., Free PMC Article | 08/19/2023 |
Phosphorylated ERM Mediates Lipopolysaccharide Induced Pulmonary Microvascular Endothelial Cells Permeability Through Negatively Regulating Rac1 Activity. | Phosphorylated ERM Mediates Lipopolysaccharide Induced Pulmonary Microvascular Endothelial Cells Permeability Through Negatively Regulating Rac1 Activity. Fei L, Sun G, Zhu Z, You Q. | 09/5/2020 |
The expression of moesin was upregulated in cardiomyocytes under inflammation, inducing protrusion formation in a phosphorylation-dependent fashion. | Moesin is activated in cardiomyocytes in experimental autoimmune myocarditis and mediates cytoskeletal reorganization with protrusion formation. Miyawaki A, Mitsuhara Y, Orimoto A, Nakayasu Y, Tsunoda S, Obana M, Maeda M, Nakayama H, Yoshioka Y, Tsutsumi Y, Fujio Y. | 07/1/2017 |
Overexpression ezrin, radixin and moesin facilitates influenza virus H1N1 replication in primary pulmonary microvascular endothelial cells. | [The transfection of lentiviral siRNA vectors targeting ezrin, radixin and moesin facilitates influenza virus replication in primary pulmonary microvascular endothelial cells]. Wu Y, Zhang S, Zhang C, Xuan Z, Li S, Gao Y, Hu Y. | 09/26/2015 |
These results indicate that ezrin, radixin, and moesin exert a redundant control on platelet derived growth factor-induced vascular smooth muscle cells migration by regulating focal adhesion turn-over and cell adhesion to substrate. | Redundant control of migration and adhesion by ERM proteins in vascular smooth muscle cells. Baeyens N, Latrache I, Yerna X, Noppe G, Horman S, Morel N. | 03/29/2014 |
Found that moesin knock-down does not affect renal Na(+) -K(+) -2Cl(-) co-transporter internalisation but strongly reduces exocytosis of the co-transporter. | Identification of moesin as NKCC2-interacting protein and analysis of its functional role in the NKCC2 apical trafficking. Carmosino M, Rizzo F, Procino G, Zolla L, Timperio AM, Basco D, Barbieri C, Torretta S, Svelto M. | 03/9/2013 |
The ERM (ezrin, radixin, moesin) proteins are novel scaffolds at the level of SOS activity control, which is relevant for both normal Ras function and dysfunction known to occur in several human cancers. | Activation of Ras requires the ERM-dependent link of actin to the plasma membrane. Sperka T, Geissler KJ, Merkel U, Scholl I, Rubio I, Herrlich P, Morrison HL., Free PMC Article | 04/7/2012 |
the activation of ROCK leads to the binding of moesin to EBP50, which interacts with several components of the cytoskeleton, resulting in a decrease in the contractile response. | Identification and functional implication of a Rho kinase-dependent moesin-EBP50 interaction in noradrenaline-stimulated artery. Baeyens N, Horman S, Vertommen D, Rider M, Morel N. | 01/8/2011 |
Data show that Hyal2, through direct interactions with CD44 and possibly some pericellular hyaluronidase activity suppresses the formation or the stability of the glycocalyx, modulates ERM-related cytoskeletal interactions, and diminishes cell motility. | Two novel functions of hyaluronidase-2 (Hyal2) are formation of the glycocalyx and control of CD44-ERM interactions. Duterme C, Mertens-Strijthagen J, Tammi M, Flamion B., Free PMC Article | 01/25/2010 |
the control of actin polymerization and branching via moesin or WAVE1 is a key function of estrogen receptor alpha in neurons, which may be particularly relevant for the regulation of dendritic spines | Rapid signaling of estrogen to WAVE1 and moesin controls neuronal spine formation via the actin cytoskeleton. Sanchez AM, Flamini MI, Fu XD, Mannella P, Giretti MS, Goglia L, Genazzani AR, Simoncini T., Free PMC Article | 01/21/2010 |
Activated ERM proteins mediate the effects of acid-induced NHE1 activation in left ventricular myocytes. | ERM proteins mediate the effects of Na+/H+ exchanger (NHE1) activation in cardiac myocytes. Darmellah A, Rücker-Martin C, Feuvray D. | 01/21/2010 |
Moesin is important in developing a specialised cytoskeleton and increased adhesiveness of decidual cells, possibly functioning to bridge adhesion molecules to the underlying cytoskeleton. | Moesin is involved in the cytoskeletal remodelling of rat decidual cells. Venuto L, Lindsay LA, Murphy CR. | 01/21/2010 |
moesin negatively regulates stable microtubule networks and is a natural determinant of cellular sensitivity to retroviral infection | Moesin regulates stable microtubule formation and limits retroviral infection in cultured cells. Naghavi MH, Valente S, Hatziioannou T, de Los Santos K, Wen Y, Mott C, Gundersen GG, Goff SP., Free PMC Article | 01/21/2010 |
RhoA and Rho kinase-dependent phosphorylation of moesin at Thr-558 in hippocampal neuronal cells by glutamate | RhoA and Rho kinase-dependent phosphorylation of moesin at Thr-558 in hippocampal neuronal cells by glutamate. Jeon S, Kim S, Park JB, Suh PG, Kim YS, Bae CD, Park J. | 01/21/2010 |
Activation of Ezrin/Radixin/Moesin proteins at the Schwann cell process tip is essential for motility and the maintenance of polarity. | Asymmetric ERM activation at the Schwann cell process tip is required in axon-associated motility. Gatto CL, Walker BJ, Lambert S. | 01/21/2010 |
Our results suggest that myosin light chain and ezrin are markers of front and tail, respectively, even in the absence of morphological polarization. We further show that endogenous ezrin and moesin are phosphorylated. | Ezrin/moesin in motile Walker 256 carcinosarcoma cells: signal-dependent relocalization and role in migration. Rossy J, Gutjahr MC, Blaser N, Schlicht D, Niggli V. | 01/21/2010 |
predominant membrane-cytoskeletal linker for L1 during migration and axon extension, neither of which requires ankyrin function | ERMs colocalize transiently with L1 during neocortical axon outgrowth. Mintz CD, Dickson TC, Gripp ML, Salton SR, Benson DL. | 01/21/2010 |
These results suggest that glutamate-induced phosphorylation of moesin may be mediated through the AMPA receptor/RhoA/Rho kinase pathway. | AMPA, not NMDA, activates RhoA GTPases and subsequently phosphorylates moesin. Kim SJ, Jeon S, Shin EY, Kim EG, Park J, Bae CD. | 01/21/2010 |
phosphorylation of moesin at Thr-558 in PC12 cells by KCl treatment is PKA- and Rac1-dependent | Chloride conductance is required for the protein kinase A and Rac1-dependent phosphorylation of moesin at Thr-558 by KCl in PC12 cells. Jeon S, Kim S, Kim E, Lee JE, Kim SJ, Juhnn YS, Kim YS, Bae CD, Park J. | 01/21/2010 |