| TGF-beta1 induced activations of Smad2 and miRNAs inhibit SF-1- and LRH-1-dependent CYP19 expression in rat Leydig cellsdagger. | TGF-β1 induced activations of Smad2 and miRNAs inhibit SF-1- and LRH-1-dependent CYP19 expression in rat Leydig cells†.
Ma B, Qiao H, Guo Y, Wei J, Yang Q, Feng X, Li Z. | 05/17/2023 |
| The effect of clomiphene citrate and human chorionic gonadotropin on the expression of CatSper1, CatSper2, LHCGR, and SF1 genes, as well as the structural changes in testicular tissue of adult rats. | The effect of clomiphene citrate and human chorionic gonadotropin on the expression of CatSper1, CatSper2, LHCGR, and SF1 genes, as well as the structural changes in testicular tissue of adult rats.
Ameli M, Moghimian M, Saeb F, Bashtani E, Shokoohi M, Salimnejad R, Abtahi H. | 05/2/2020 |
| In conclusion, the presented data revealed that the pituitary Nr5a1/Ctnnb1/Nr0b1 system is controlled by endogenous Gnrh network activity, and hypothalamic-derived regulatory inputs can affect the processes responsible for gene transcription, translation, and protein intracellular translocation. | Gonadotropin-releasing hormone and kisseptin-10 regulate nuclear receptor subfamily 5 group a member 1/catenin beta 1/ nuclear receptor subfamily 0 group B member 1 activity in female rat anterior pituitary gland.
Zielinska-Gorska M, Gorski K, Biernacka K, Sawosy E, Kaminska T, Gajewska A. | 12/22/2018 |
| DNA methylation might play a role in the downregulation of SF-1 gene expression induced by soy isoflavones. | Continuous soy isoflavones exposure from weaning to maturity induces downregulation of ovarian steroidogenic factor 1 gene expression and corresponding changes in DNA methylation pattern.
Wang W, Sun Y, Guo Y, Cai P, Li Y, Liu J, Cai G, Kiyoshi A, Zhang W. | 11/11/2017 |
| These results suggest that the low level of DAX-1 may enhance the transcriptional activity of SF-1 and expression of genes related to glucocorticoid synthesis, which are targeted by SF-1, in adrenals from SHR. | Characteristic induction of steroidogenic factor 1 (SF-1) and DAX-1 and enhanced expression of glucocorticoid synthesis-related genes in adrenals from spontaneously hypertensive rats.
Harikai N. | 01/12/2013 |
| Upstream stimulatory factors (USF1 and USF2) induce Nr5a1 and Shbg gene expression during the onset of rat Sertoli cell differentiation. | Upstream stimulatory factor induces Nr5a1 and Shbg gene expression during the onset of rat Sertoli cell differentiation.
Wood MA, Mukherjee P, Toocheck CA, Walker WH., Free PMC Article | 03/24/2012 |
| Binding of steroidogenic factor-1 (SF-1) to the StAR promoter region was also enhanced by PTU treatment, which suggests that propylthiouracil could upregulate StAR gene expression. | Stimulatory effects of propylthiouracil on pregnenolone production through upregulation of steroidogenic acute regulatory protein expression in rat granulosa cells.
Chen MC, Wang SW, Kan SF, Tsai SC, Wu YC, Wang PS. | 03/5/2011 |
| FGF2 inhibited the expressions of steroidogenic acute regulatory (StAR) protein and steroidogenic factor 1 (Nr5a1) in LH-stimulated immature Leydig cells. | Inhibition of LH-stimulated androgen production in rat immature Leydig cells: Effects on nuclear receptor steroidogenic factor 1 by FGF2.
Xiao YC, Hardy DO, Sottas CM, Li XK, Ge RS. | 04/12/2010 |
| FXR is able to compete with steroidogenic factor 1 in binding to a common sequence present in the aromatase promoter region interfering negatively with its activity. | Farnesoid X receptor, through the binding with steroidogenic factor 1-responsive element, inhibits aromatase expression in tumor Leydig cells.
Catalano S, Malivindi R, Giordano C, Gu G, Panza S, Bonofiglio D, Lanzino M, Sisci D, Panno ML, Andò S., Free PMC Article | 03/15/2010 |
| Inhibin A is capable of feedback antagonizing FSH action on GCs by reducing FSHR expression at ovarian level via a short feedback loop. Transcriptional factor receptors, such as SF-1, AR and DAX-1 were involved in this regulation. | Inhibin A inhibits follicle-stimulating hormone (FSH) action by suppressing its receptor expression in cultured rat granulosa cells.
Lu C, Yang W, Chen M, Liu T, Yang J, Tan P, Li L, Hu X, Fan C, Hu Z, Liu Y. | 01/21/2010 |
| ERK activity was required for SF-1 phosphorylation to upregulate steroidogenesis in rat ZFR cells | Mechanisms of inhibition of dehydroepiandrosterone upon corticosterone release from rat zona fasciculata-reticularis cells.
Chang LL, Wun WS, Wang PS. | 01/21/2010 |
| Leydig tumor cell-produced IGF-I amplifies estrogen signaling through an SF-1-dependent up-regulation of aromatase expression. | Insulin-like growth factor-I, regulating aromatase expression through steroidogenic factor 1, supports estrogen-dependent tumor Leydig cell proliferation.
Sirianni R, Chimento A, Malivindi R, Mazzitelli I, Andò S, Pezzi V. | 01/21/2010 |
| Dexamethasone had no effect on the level of SF-1, but increased the amount of complexed DAX-1-SF-1. | In vivo inhibition of steroidogenic acute regulatory protein expression by dexamethasone parallels induction of the negative transcription factor DAX-1.
Yu CC, Li PH. | 01/21/2010 |
| Review. SF-1 plays a decisive role in tissue-specific expression of the GNRH receptor. It interacts with proteins related to the GATA and LIM homeodomain families, and a CREB-related factor in the stimulatory action of PACAP on promoter activity. | [An ambiguous role of steroidogenic factor 1 in the rat GnRH receptor gene expression. Lessons from transgenic mice].
Laverrière JN, Granger A, Pincas H, Ngô-Muller V, Bleux C, Tixier-Vidal A, Magre S, Guigon C, Daegelen D, Counis R. | 01/21/2010 |
| data indicate that granulosa cells of small and preovulatory follicles express both SF-1 and FTF/LRH-1 and that each orphan receptor may regulate target gene expression in these cells | Differential expression of steroidogenic factor-1 and FTF/LRH-1 in the rodent ovary.
Falender AE, Lanz R, Malenfant D, Belanger L, Richards JS. | 01/21/2010 |
| the SULT2A1 gene is mediated by SF1 and indirectly regulated by T(3) | Indirect regulation of human dehydroepiandrosterone sulfotransferase family 1A member 2 by thyroid hormones.
Huang YH, Lee CY, Tai PJ, Yen CC, Liao CY, Chen WJ, Liao CJ, Cheng WL, Chen RN, Wu SM, Wang CS, Lin KH. | 01/21/2010 |
| Sox9 up-regulates SF-1 and accounts partially for the sexually dimorphic expression pattern of SF-1 [sf-1] | Regulation of the orphan nuclear receptor steroidogenic factor 1 by Sox proteins.
Shen JH, Ingraham HA. | 01/21/2010 |