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    CASP9 caspase 9 [ Homo sapiens (human) ]

    Gene ID: 842, updated on 5-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Caspase-9-mediated cleavage of vimentin attenuates the aggressiveness of leukemic NB4 cells.

    Caspase-9-mediated cleavage of vimentin attenuates the aggressiveness of leukemic NB4 cells.
    Hakim F, Kazemiraad C, Akbari-Birgani S, Abdollahpour D, Mohammadi S.

    01/17/2024
    GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma.

    GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma.
    Del Bufalo F, De Angelis B, Caruana I, Del Baldo G, De Ioris MA, Serra A, Mastronuzzi A, Cefalo MG, Pagliara D, Amicucci M, Li Pira G, Leone G, Bertaina V, Sinibaldi M, Di Cecca S, Guercio M, Abbaszadeh Z, Iaffaldano L, Gunetti M, Iacovelli S, Bugianesi R, Macchia S, Algeri M, Merli P, Galaverna F, Abbas R, Garganese MC, Villani MF, Colafati GS, Bonetti F, Rabusin M, Perruccio K, Folsi V, Quintarelli C, Locatelli F, Precision Medicine Team–IRCCS Ospedale Pediatrico Bambino Gesù.

    04/7/2023
    Association between blood caspase-9 concentrations and septic patient prognosis.

    Association between blood caspase-9 concentrations and septic patient prognosis.
    Lorente L, Martín MM, Ortiz-López R, Pérez-Cejas A, Gómez-Bernal F, González-Mesa A, Jiménez A, González-Rivero AF.

    02/24/2023
    The Effect of Caspase 8, 9 Gene Polymorphisms on Non-Hodgkin Lymphoma Susceptibility and Clinical/Pathological Features.

    The Effect of Caspase 8, 9 Gene Polymorphisms on Non-Hodgkin Lymphoma Susceptibility and Clinical/Pathological Features.
    Barati F, Bahari G, Asadi A, Nakhaee A, Hashemi SM, Taheri M, Hashemi M., Free PMC Article

    01/11/2023
    Caspase 9b Drives Cellular Transformation, Lung Inflammation, and Lung Tumorigenesis.

    Caspase 9b Drives Cellular Transformation, Lung Inflammation, and Lung Tumorigenesis.
    Kim M, Vu NT, Wang X, Bulut GB, Wang MH, Uram-Tuculescu C, Pillappa R, Kim S, Chalfant CE., Free PMC Article

    08/13/2022
    Correlation between BTG3, CASP9 and LRP4 single-nucleotide polymorphisms and susceptibility to papillary thyroid carcinoma.

    Correlation between BTG3, CASP9 and LRP4 single-nucleotide polymorphisms and susceptibility to papillary thyroid carcinoma.
    Zhang F, Fan G, Wang X.

    04/16/2022
    Evaluation of the association between biochemical and immunohistochemical score of caspase-9 and TNFalpha, and the grading of lumbar disc herniation.

    Evaluation of the association between biochemical and immunohistochemical score of caspase-9 and TNFα, and the grading of lumbar disc herniation.
    Ozevren H, Cetin A, Baloglu M, Deveci E.

    02/5/2022
    Relationship Between CASP9 and CASP10 Gene Polymorphisms and Cancer Susceptibility: Evidence from an Updated Meta-analysis.

    Relationship Between CASP9 and CASP10 Gene Polymorphisms and Cancer Susceptibility: Evidence from an Updated Meta-analysis.
    Sargazi S, Abghari AZ, Sarani H, Sheervalilou R, Mirinejad S, Saravani R, Eskandari E.

    01/22/2022
    C-reactive protein promotes tongue squamous cell carcinoma chemoresistance by inhibiting the activation of caspase-3/9 via the CD64/AKT/mTOR pathway.

    C-reactive protein promotes tongue squamous cell carcinoma chemoresistance by inhibiting the activation of caspase-3/9 via the CD64/AKT/mTOR pathway.
    Yan X, Cao M, Wang Z, Wang S, Chen Q.

    01/1/2022
    Involvement of CASP9 (caspase 9) in IGF2R/CI-MPR endosomal transport.

    Involvement of CASP9 (caspase 9) in IGF2R/CI-MPR endosomal transport.
    Han J, Goldstein LA, Hou W, Watkins SC, Rabinowich H., Free PMC Article

    01/1/2022
    lncRNA PROX1-AS1 mediates the migration and invasion of placental trophoblast cells via the miR-211-5p/caspase-9 axis.

    lncRNA PROX1-AS1 mediates the migration and invasion of placental trophoblast cells via the miR-211-5p/caspase-9 axis.
    Tang D, Geng L, Ma J., Free PMC Article

    11/13/2021
    The effect of caspase-9 in the differentiation of SH-SY5Y cells.

    The effect of caspase-9 in the differentiation of SH-SY5Y cells.
    Madadi Z, Akbari-Birgani S, Mohammadi S, Khademy M, Mousavi SA.

    11/6/2021
    GABA synaptopathy promotes the elevation of caspases 3 and 9 as pro-apoptotic markers in Egyptian patients with autism spectrum disorder.

    GABA synaptopathy promotes the elevation of caspases 3 and 9 as pro-apoptotic markers in Egyptian patients with autism spectrum disorder.
    El-Ansary A, Zayed N, Al-Ayadhi L, Qasem H, Anwar M, Meguid NA, Bhat RS, Doşa MD, Chirumbolo S, Bjørklund G.

    11/6/2021
    CASP9 (caspase 9) is essential for autophagosome maturation through regulation of mitochondrial homeostasis.

    CASP9 (caspase 9) is essential for autophagosome maturation through regulation of mitochondrial homeostasis.
    An HK, Chung KM, Park H, Hong J, Gim JE, Choi H, Lee YW, Choi J, Mun JY, Yu SW., Free PMC Article

    07/31/2021
    Fruiting body polysaccharides of Hericium erinaceus induce apoptosis in human colorectal cancer cells via ROS generation mediating caspase-9-dependent signaling pathways.

    Fruiting body polysaccharides of Hericium erinaceus induce apoptosis in human colorectal cancer cells via ROS generation mediating caspase-9-dependent signaling pathways.
    Hou XX, Liu JY, Li ZY, Chang MC, Guo M, Feng CP, Shi JY.

    05/8/2021
    LncRNA UNC5B-AS1 promotes malignant progression of prostate cancer by competitive binding to caspase-9.

    LncRNA UNC5B-AS1 promotes malignant progression of prostate cancer by competitive binding to caspase-9.
    Tan SF, Ni JX, Xiong H.

    03/20/2021
    Inactivation of the Cytoprotective Major Vault Protein by Caspase-1 and -9 in Epithelial Cells during Apoptosis.

    Inactivation of the Cytoprotective Major Vault Protein by Caspase-1 and -9 in Epithelial Cells during Apoptosis.
    Grossi S, Fenini G, Kockmann T, Hennig P, Di Filippo M, Beer HD.

    03/6/2021
    LINC01980 stimulates the progression of hepatocellular carcinoma via downregulating caspase 9.

    LINC01980 stimulates the progression of hepatocellular carcinoma via downregulating caspase 9.
    Zang Y, Yi Q, Pan J, Ding M, Zuo X, Hu X.

    02/13/2021
    Influence of CASP9 c.-1339A>G and CASP3 c.-1191A>G variants in outcome of patients with head and neck squamous cell carcinoma.

    Influence of CASP9 c.-1339A>G and CASP3 c.-1191A>G variants in outcome of patients with head and neck squamous cell carcinoma.
    Carvalho BF, Costa EFD, Lopes-Aguiar L, Liutti VT, Leal F, Vasconcelos VCA, Rinck-Junior JA, Lourenço GJ, Lima CSP.

    12/26/2020
    Upregulation of CASP9 through NF-kappaB and Its Target MiR-1276 Contributed to TNFalpha-promoted Apoptosis of Cancer Cells Induced by Doxorubicin.

    Upregulation of CASP9 through NF-κB and Its Target MiR-1276 Contributed to TNFα-promoted Apoptosis of Cancer Cells Induced by Doxorubicin.
    Zhou F, Li Y, Huang Y, Wu J, Wu Q, Zhu H, Wang J., Free PMC Article

    12/19/2020
    Major Contribution of Caspase-9 to Honokiol-Induced Apoptotic Insults to Human Drug-Resistant Glioblastoma Cells.

    Major Contribution of Caspase-9 to Honokiol-Induced Apoptotic Insults to Human Drug-Resistant Glioblastoma Cells.
    Wu GJ, Yang ST, Chen RM., Free PMC Article

    12/19/2020
    CASP9 c.-1339A>G and CASP3 c.-1191A>G polymorphisms alter susceptibility and clinical aspects of head and neck squamous cell carcinoma.

    CASP9 c.-1339A>G and CASP3 c.-1191A>G polymorphisms alter susceptibility and clinical aspects of head and neck squamous cell carcinoma.
    Costa EFD, Lopes-Aguiar L, Nogueira GS, Lima TRP, Rinck-Junior JA, Lourenço GJ, Lima CSP.

    11/28/2020
    Transit of Procaspase-9 towards its activation. New mechanistic insights from molecular dynamics simulations.

    Transit of Procaspase-9 towards its activation. New mechanistic insights from molecular dynamics simulations.
    Gasperin-Sánchez H, Benítez-Cardoza CG, Caro-Gómez LA, Rosas-Trigueros JL, Zamorano-Carrillo A.

    10/10/2020
    Bcl-2 levels were found to be significantly higher in the maternal and umbilical cord sera in the intrauterine growth restriction group compared with controls. There was no significant difference between umbilical cord sera of the two groups in terms of sFasL and caspase-9 levels.

    Serum Bcl-2, caspase-9 and soluble FasL levels as perinatal markers in late preterm pregnancies with intrauterine growth restriction.
    Genç ŞÖ, Karakuş S, Çetin A, Çetin M, Doğan HO, Korgalı EÜ.

    07/25/2020
    Owing to the evidence, caspase-9 activity is considered as a central factor in the execution of differentiation in leukemic cells.

    The non-apoptotic role of caspase-9 promotes differentiation in leukemic cells.
    Madadi Z, Akbari-Birgani S, Monfared PD, Mohammadi S.

    03/21/2020
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