| ATRN encodes Attractin, which was previously shown to play a critical role in central myelination | Hypomyelinating leukodystrophy associated with a deleterious mutation in the ATRN gene.
Shahrour MA, Ashhab M, Edvardson S, Gur M, Abu-Libdeh B, Elpeleg O. | 04/28/2018 |
| Data indicate that Attractin was involved in male reproduction in both human and BALB/c mice, but it exerted a different expression profile in different species. | Expression of Attractin in male reproductive tract of human and mice and its correlation with male reproduction.
Cheng D, Ming Y, Li J, Chi Y, Li HG, Zou YJ, Xiong CL. | 05/2/2015 |
| The levels of both dipeptidyl-peptidase 4 and attractin in circulating monocytes were significantly higher in obese subjects as compared with levels in lean controls or in subjects with type 2 diabetes. | Dipeptidyl-peptidase 4 and attractin expression is increased in circulating blood monocytes of obese human subjects.
Laudes M, Oberhauser F, Schulte DM, Schilbach K, Freude S, Bilkovski R, Schulz O, Faust M, Krone W. | 01/15/2011 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| associated with spermatozoa | Novel partners of SPAG11B isoform D in the human male reproductive tract.
Radhakrishnan Y, Hamil KG, Tan JA, Grossman G, Petrusz P, Hall SH, French FS., Free PMC Article | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesGenetic variants in pigmentation genes, pigmentary phenotypes, and risk of skin cancer in Caucasians.
Nan H, Kraft P, Hunter DJ, Han J. Pigmentation-related genes and their implication in malignant melanoma susceptibility.
Fernandez LP, Milne RL, Pita G, Floristan U, Sendagorta E, Feito M, Avilés JA, Martin-Gonzalez M, Lázaro P, Benítez J, Ribas G. | 04/8/2009 |
| It is the first time expression of attractin on monocytes and provide first data suggesting that drugs directed to DP IV-like enzyme activity could affect monocyte function via attractin inhibition. | Attractin, a dipeptidyl peptidase IV/CD26-like enzyme, is expressed on human peripheral blood monocytes and potentially influences monocyte function.
Wrenger S, Faust J, Friedrich D, Hoffmann T, Hartig R, Lendeckel U, Kähne T, Thielitz A, Neubert K, Reinhold D. | 01/21/2010 |
| This protein is isolated from human blood and characterized. | Isolation and characterization of attractin-2.
Friedrich D, Kühn-Wache K, Hoffmann T, Demuth HU. | 01/21/2010 |
| The product of the murine "Mahogany" locus, controlling agouti-mediated melanocyte pigmentation and control of energy metabolism, is the murine ortholog of human attractin. | The mouse mahogany locus encodes a transmembrane form of human attractin.
Gunn TM, Miller KA, He L, Hyman RW, Davis RW, Azarani A, Schlossman SF, Duke-Cohan JS, Barsh GS. | 08/25/2000 |
| Through use of PCR from hamster-human somatic cell hybrids, localizes the EST AB011120 (KIAA0548) to human chromosome 20p13. AB011120 encodes the central to 3' UTR of the membrane form of human attractin. | Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
Nagase T, Ishikawa K, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O. | 08/25/2000 |
| The product of the murine "Mahogany" gene controls energy metabolism and is the murine orthologof human membrane attractin. | The mahogany protein is a receptor involved in suppression of obesity.
Nagle DL, McGrail SH, Vitale J, Woolf EA, Dussault BJ Jr, DiRocco L, Holmgren L, Montagno J, Bork P, Huszar D, Fairchild-Huntress V, Ge P, Keilty J, Ebeling C, Baldini L, Gilchrist J, Burn P, Carlson GA, Moore KJ. | 06/4/2002 |
| Provides the genomic basis for production of a soluble and membrane form of attractin by alternative splicing. In the process, by sequencing from positionally-determined BAC clones, confirms the localization of attractin to chromosome 20p13. | Secreted and membrane attractin result from alternative splicing of the human ATRN gene.
Tang W, Gunn TM, McLaughlin DF, Barsh GS, Schlossman SF, Duke-Cohan JS., Free PMC Article | 08/25/2000 |