| Maturity-onset diabetes of the young type 7 (MODY7) and mutation in the Kruppel-like transcription factor 11 (KLF11) gene. | Maturity-onset diabetes of the young type 7 (MODY7) and mutation in the Krüppel-like transcription factor 11 (KLF11) gene.
Wang Y, Ye X, Chen X, Zang H, Shen Q, Chen L., Free PMC Article | 03/29/2024 |
| Maturity-onset Diabetes of the Young Type 7 (MODY7) and the Kruppellike Factor 11 Mutation (KLF11). A Review. | Maturity-onset Diabetes of the Young Type 7 (MODY7) and the Krüppellike Factor 11 Mutation (KLF11). A Review.
Mancera-Rincón P, Luna-España MC, Rincon O, Guzmán I, Alvarez M. | 02/7/2024 |
| KLF11 regulates lung adenocarcinoma ferroptosis and chemosensitivity by suppressing GPX4. | KLF11 regulates lung adenocarcinoma ferroptosis and chemosensitivity by suppressing GPX4.
Zhao G, Liang J, Shan G, Gu J, Xu F, Lu C, Ma T, Bi G, Zhan C, Ge D., Free PMC Article | 07/19/2023 |
| Genetic and Functional Analyses of the Novel KLF11 Pro193Thr Variant in a Three-Generation Family with MODY7. | Genetic and Functional Analyses of the Novel KLF11 Pro193Thr Variant in a Three-Generation Family with MODY7.
Guan G, Qin T, Zhao LL, Jin P. | 02/4/2023 |
| Endothelial KLF11 as a Nephroprotectant in AKI. | Endothelial KLF11 as a Nephroprotectant in AKI.
Ghajar-Rahimi G, Agarwal A., Free PMC Article | 10/15/2022 |
| KLF11 Is a Novel Endogenous Protectant against Renal Ischemia-Reperfusion Injury. | KLF11 Is a Novel Endogenous Protectant against Renal Ischemia-Reperfusion Injury.
Nath KA, Singh RD, Croatt AJ, Ackerman AW, Grande JP, Khazaie K, Chen YE, Zhang J., Free PMC Article | 10/15/2022 |
| A novel KLF11 variant in a family with maturity-onset diabetes of the young. | A novel KLF11 variant in a family with maturity-onset diabetes of the young.
Wu S, Zhang G, Liu L, Wu W, Luo X. | 07/30/2022 |
| KLF11 promotes the progression of glioma via regulating Holliday junction recognition protein. | KLF11 promotes the progression of glioma via regulating Holliday junction recognition protein.
Li J, Wang C, Cheng R, Su H, Wang L, Ji L, Ji H. | 07/2/2022 |
| KLF11 Protects against Venous Thrombosis via Suppressing Tissue Factor Expression. | KLF11 Protects against Venous Thrombosis via Suppressing Tissue Factor Expression.
Liang W, Lu H, Sun J, Zhao G, Wang H, Guo Y, Eitzman D, Chen YE, Fan Y, Zhang J., Free PMC Article | 06/18/2022 |
| Evaluation of Evidence for Pathogenicity Demonstrates That BLK, KLF11, and PAX4 Should Not Be Included in Diagnostic Testing for MODY. | Evaluation of Evidence for Pathogenicity Demonstrates That BLK, KLF11, and PAX4 Should Not Be Included in Diagnostic Testing for MODY.
Laver TW, Wakeling MN, Knox O, Colclough K, Wright CF, Ellard S, Hattersley AT, Weedon MN, Patel KA., Free PMC Article | 04/30/2022 |
| Genome-wide CRISPR-Cas9 screen identified KLF11 as a druggable suppressor for sarcoma cancer stem cells. | Genome-wide CRISPR-Cas9 screen identified KLF11 as a druggable suppressor for sarcoma cancer stem cells.
Wang Y, Wu J, Chen H, Yang Y, Xiao C, Yi X, Shi C, Zhong K, He H, Li Y, Wu Z, Zhou G, Rao Q, Wang X, Zhou X, Lomberk G, Liu B, Zhao J, Ge J, Zhou W, Chu X, Chen C, Zhou X, Wang L, Guan K, Qu L., Free PMC Article | 04/23/2022 |
| KLF11 protects against abdominal aortic aneurysm through inhibition of endothelial cell dysfunction. | KLF11 protects against abdominal aortic aneurysm through inhibition of endothelial cell dysfunction.
Zhao G, Chang Z, Zhao Y, Guo Y, Lu H, Liang W, Rom O, Wang H, Sun J, Zhu T, Fan Y, Chang L, Yang B, Garcia-Barrio MT, Chen YE, Zhang J., Free PMC Article | 01/15/2022 |
| Clinical and Functional Characteristics of a Novel KLF11 Cys354Phe Variant Involved in Maturity-Onset Diabetes of the Young. | Clinical and Functional Characteristics of a Novel KLF11 Cys354Phe Variant Involved in Maturity-Onset Diabetes of the Young.
Sun Y, Qu J, Wang J, Zhao R, Wang C, Chen L, Hou X., Free PMC Article | 11/6/2021 |
| DNA hypomethylation of the Kruppel-like factor 11 (KLF11) gene promoter: a putative biomarker of depression comorbidity in panic disorder and of non-anxious depression? | DNA hypomethylation of the Krüppel-like factor 11 (KLF11) gene promoter: a putative biomarker of depression comorbidity in panic disorder and of non-anxious depression?
Kollert L, Schiele MA, Thiel C, Menke A, Deckert J, Domschke K., Free PMC Article | 10/23/2021 |
| Prognostic Role of Kruppel-Like Factors 5, 9, and 11 in Endometrial Endometrioid Cancer. | Prognostic Role of Krüppel-Like Factors 5, 9, and 11 in Endometrial Endometrioid Cancer.
Viola L, Londero AP, Bertozzi S, Orsaria M, Marzinotto S, Antoniazzi F, Renda V, Cinel J, Fruscalzo A, Lellé RJ, Mariuzzi L. | 07/17/2021 |
| KLF11 protects chondrocytes via inhibiting p38 MAPK signaling pathway. | KLF11 protects chondrocytes via inhibiting p38 MAPK signaling pathway.
Han F, Jiang H, Qu W, Rui YJ. | 04/17/2021 |
| Specific variants of KLF11 (MODY7) with a dominant-negative effect underlie early childhood-onset type 1B diabetes with incomplete penetrance. This study documents a novel monogenic mutation associated with diabetes in children. | KLF11 variant in a family clinically diagnosed with early childhood-onset type 1B diabetes.
Ushijima K, Narumi S, Ogata T, Yokota I, Sugihara S, Kaname T, Horikawa Y, Matsubara Y, Fukami M, Kawamura T, Japanese Study Group of Insulin Therapy for Childhood and Adolescent Diabetes. | 05/16/2020 |
| In human aortic smooth muscle cells, small interfering RNA-mediated knockdown of KLF11 increased tissue factor expression. | KLF11 (Krüppel-Like Factor 11) Inhibits Arterial Thrombosis via Suppression of Tissue Factor in the Vascular Wall.
Liang W, Fan Y, Lu H, Chang Z, Hu W, Sun J, Wang H, Zhu T, Wang J, Adili R, Garcia-Barrio MT, Holinstat M, Eitzman D, Zhang J, Chen YE., Free PMC Article | 01/18/2020 |
| microRNA-30d mediated breast cancer invasion, migration, and epithelial-mesenchymal transition by targeting KLF11 and activating STAT3 pathway. | microRNA-30d mediated breast cancer invasion, migration, and EMT by targeting KLF11 and activating STAT3 pathway.
Han M, Wang Y, Guo G, Li L, Dou D, Ge X, Lv P, Wang F, Gu Y. | 10/12/2019 |
| KLF11 has a critical role in regulating gastric cancer migration and invasion by increasing Twist1 expression | KLF11 promotes gastric cancer invasion and migration by increasing Twist1 expression.
Ji Q, Li Y, Zhao Q, Fan LQ, Tan BB, Zhang ZD, Zhao XF, Liu Y, Wang D, Jia N. | 08/17/2019 |
| Profibrotic gene expression was activated in a primary human peritoneal cell line in response to KLF11 short hairpin RNA and medroxyprogesterone acetate but not estradiol. | Progressive Fibrosis: A Progesterone- and KLF11-Mediated Sexually Dimorphic Female Response.
Shenoy CC, Khan Z, Zheng Y, Jones TL, Khazaie K, Daftary GS. | 10/21/2017 |
| In endometrial-stromal fibroblasts, KLF11 recruited SIN3A/HDAC (histone deacetylase), resulting in COL1A1-promoter deacetylation and repression | Epigenetic Modulation of Collagen 1A1: Therapeutic Implications in Fibrosis and Endometriosis.
Zheng Y, Khan Z, Zanfagnin V, Correa LF, Delaney AA, Daftary GS. | 02/18/2017 |
| Results suggest a role for KLF11 in upregulating MAO-A in depressive disorder and chronic social stress, suggesting that inhibition of the pathways regulated by this transcription factor may aid in the therapeutics of neuropsychiatric illnesses | Evidence revealing deregulation of the KLF11-MAO A pathway in association with chronic stress and depressive disorders.
Harris S, Johnson S, Duncan JW, Udemgba C, Meyer JH, Albert PR, Lomberk G, Urrutia R, Ou XM, Stockmeier CA, Wang JM., Free PMC Article | 04/2/2016 |
| The data suggest a relationship between promoter DNA methylation and KLF11 gene expression in ovarian cancer tumorigenesis. | Promoter DNA methylation is associated with KLF11 expression in epithelial ovarian cancer.
Wang G, Li X, Tian W, Wang Y, Wu D, Sun Z, Zhao E. | 02/6/2016 |
| identified an evolutionarily conserved metabolic regulator, Kruppel-like factor 11 (KLF11), as a novel browning transcription factor in human adipocytes that is required for rosiglitazone-induced browning. | Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers.
Loft A, Forss I, Siersbæk MS, Schmidt SF, Larsen AS, Madsen JG, Pisani DF, Nielsen R, Aagaard MM, Mathison A, Neville MJ, Urrutia R, Karpe F, Amri EZ, Mandrup S., Free PMC Article | 02/28/2015 |