DEC1 is involved in circadian rhythm disruption-exacerbated pulmonary fibrosis.
Chen SJ, Yu F, Feng X, Li Q, Jiang YH, Zhao LQ, Cheng PP, Wang M, Song LJ, Liang LM, He XL, Xiong L, Xiang F, Wang X, Ye H, Ma WL., Free PMC Article

The BHLHE40‒PPM1F‒AMPK pathway regulates energy metabolism and is associated with the aggressiveness of endometrial cancer.
Asanoma K, Yagi H, Onoyama I, Cui L, Hori E, Kawakami M, Maenohara S, Hachisuga K, Tomonobe H, Kodama K, Yasunaga M, Ohgami T, Okugawa K, Yahata H, Kitao H, Kato K., Free PMC Article

BHLHE40, a potential immune therapy target, regulated by FGD5-AS1/miR-15a-5p in pancreatic cancer.
Qi W, Liu Q, Fu W, Shi J, Shi M, Duan S, Li Z, Song S, Wang J, Liu Y., Free PMC Article

High expression of BHLHE40 promotes immune infiltration and tumor progression in thyroid cancer.
Gong Q, Li H.

HIF-1α contributes to metastasis in choriocarcinoma by regulating DEC1 expression.
Xu Y, Ren B, Wang M.

Overcoming ABCB1-mediated multidrug resistance by transcription factor BHLHE40.
Yin Y, Xin Y, Zhang F, An D, Fan H, Qin M, Xia J, Xi T, Xiong J., Free PMC Article

Single-cell RNA-seq analysis reveals BHLHE40-driven pro-tumour neutrophils with hyperactivated glycolysis in pancreatic tumour microenvironment.
Wang L, Liu Y, Dai Y, Tang X, Yin T, Wang C, Wang T, Dong L, Shi M, Qin J, Xue M, Cao Y, Liu J, Liu P, Huang J, Wen C, Zhang J, Xu Z, Bai F, Deng X, Peng C, Chen H, Jiang L, Chen S, Shen B., Free PMC Article

Differentiated embryonic chondrocyte expressed gene-1 is a central signaling component in the development of collagen-induced rheumatoid arthritis.
Wu Y, Wang H, Huo Y, Yan B, Honda H, Liu W, Yang J., Free PMC Article

High serum Bhlhe40 levels are associated with subclinical atherosclerosis in patients with type 2 diabetes mellitus: A cross-sectional study.
Xu H, Xiang QY, Li S, Liu YS., Free PMC Article

Long noncoding RNA SNHG1 alleviates high glucose-induced vascular smooth muscle cells calcification/senescence by post-transcriptionally regulating Bhlhe40 and autophagy via Atg10.
Li S, Ni Y, Li C, Xiang Q, Zhao Y, Xu H, Huang W, Wang Y, Wang Y, Zhan J, Liu Y., Free PMC Article

Overexpression of DEC1 in the epithelium of OSF promotes mesenchymal transition via activating FAK/Akt signal axis.
Hu X, Wang W, Hu Y, Chen W, Wang C, Yang L, Mao T, Xia K, Min A, Xiong H, Su T.

Upregulation of INHBA mediated by the transcription factor BHLHE40 promotes colon cancer cell proliferation and migration.
Wang J, Li B, Yang S, Ma C, Liu K, Chen X, Cui W., Free PMC Article

REL and BHLHE40 Variants Are Associated with IL-12 and IL-10 Responses and Tuberculosis Risk.
Shah JA, Warr AJ, Graustein AD, Saha A, Dunstan SJ, Thuong NTT, Thwaites GE, Caws M, Thai PVK, Bang ND, Chau TTH, Khor CC, Li Z, Hibberd M, Chang X, Nguyen FK, Hernandez CA, Jones MA, Sassetti CM, Fitzgerald KA, Musvosvi M, Gela A, Hanekom WA, Hatherill M, Scriba TJ, Hawn TR., Free PMC Article

Differentiated embryonic chondrocyte expressed gene-1 (DEC1) enhances the development of colorectal cancer with an involvement of the STAT3 signaling.
Shan E, Huo Y, Wang H, Zhang Z, Hu J, Wang G, Liu W, Yan B, Hiroaki H, Yang J., Free PMC Article

Role of differentiated embryo-chondrocyte expressed gene 1 (DEC1) in immunity.
Yuan NL, Liu Y, Zhang D.

Differentiated embryo chondrocyte 1, induced by hypoxia-inducible factor 1α, promotes cell migration in oral squamous cell carcinoma cell lines.
Yang L, Zeng L, Wang Z, Hu X, Xiong H, Zhang T, Chen W, Xia K, Su T.

Hypoxia-induced DEC1 mediates trophoblast cell proliferation and migration via HIF1α signaling pathway.
Hu R, Wang Q, Jia Y, Zhang Y, Wu B, Tian S, Wang Y, Wang Y, Ma W.

DEC1 negatively regulates CYP2B6 expression by binding to the CYP2B6 promoter region ascribed to IL-6-induced downregulation of CYP2B6 expression in HeLa cells.
Luan X, Zhao Y, Bu N, Chen Y, Chen N.

TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41.
Carey KL, Paulus GLC, Wang L, Balce DR, Luo JW, Bergman P, Ferder IC, Kong L, Renaud N, Singh S, Kost-Alimova M, Nyfeler B, Lassen KG, Virgin HW, Xavier RJ., Free PMC Article

Identification of BHLHE40 expression in peripheral blood mononuclear cells as a novel biomarker for diagnosis and prognosis of hepatocellular carcinoma.
Kunadirek P, Ariyachet C, Sriphoosanaphan S, Pinjaroen N, Sirichindakul P, Nookaew I, Chuaypen N, Tangkijvanich P., Free PMC Article

The Potential Roles of Dec1 and Dec2 in Periodontal Inflammation.
Wang X, Sato F, Tanimoto K, Rajeshwaran N, Thangavelu L, Makishima M, Bhawal UK., Free PMC Article

BHLHE40 plays a pathological role in pre-eclampsia through upregulating SNX16 by transcriptional inhibition of miR-196a-5p.
Mi C, Ye B, Gao Z, Du J, Li R, Huang D.

Loss of Dec1 prevents autophagy in inflamed periodontal ligament fibroblast.
Oka S, Li X, Zhang F, Tewari N, Kim IS, Chen C, Zhong L, Hamada N, Oi Y, Makishima M, Liu Y, Bhawal UK.

DEC1 directly interacts with estrogen receptor (ER) α to suppress proliferation of ER-positive breast cancer cells.
Xue J, Dai Y, Li G, Lang W, Li P, Liu Y, Bao H, Zhao D, Pan H.

LncRNA-ES3 inhibition by Bhlhe40 is involved in high glucose-induced calcification/senescence of vascular smooth muscle cells.
Zhong JY, Cui XJ, Zhan JK, Wang YJ, Li S, Lin X, Xiang QY, Ni YQ, Liu L, Liu YS.