| Novel insights into the recognition of acetylated histone H4 tail by the TRIM24 PHD-Bromo module. | Novel insights into the recognition of acetylated histone H4 tail by the TRIM24 PHD-Bromo module.
Bardhan I, Barman S, Roy A, Sudhamalla B. | 05/17/2023 |
| TRIM24 is critical for the cellular response to DNA double-strand breaks through regulating the recruitment of MRN complex. | TRIM24 is critical for the cellular response to DNA double-strand breaks through regulating the recruitment of MRN complex.
Wang Y, Yao Y, Wei Q, Long S, Chen Y, Xie J, Tan R, Jiang W, Zhang Q, Wu D, Xiao S, Wan F, Fu K. | 02/27/2023 |
| TRIM24 controls induction of latent HIV-1 by stimulating transcriptional elongation. | TRIM24 controls induction of latent HIV-1 by stimulating transcriptional elongation.
Horvath RM, Dahabieh M, Malcolm T, Sadowski I., Free PMC Article | 02/4/2023 |
| miR-339-3p inhibits cell growth and epithelial-mesenchymal transition in nasopharyngeal carcinoma by modulating the KAT6A/TRIM24 axis. | miR-339-3p inhibits cell growth and epithelial-mesenchymal transition in nasopharyngeal carcinoma by modulating the KAT6A/TRIM24 axis.
Gao P, Zhao K, Lu W, Wang L, Zhang P. | 11/5/2022 |
| STAT1 is regulated by TRIM24 and promotes immunosuppression in head and neck squamous carcinoma cells, but enhances T cell antitumour immunity in the tumour microenvironment. | STAT1 is regulated by TRIM24 and promotes immunosuppression in head and neck squamous carcinoma cells, but enhances T cell antitumour immunity in the tumour microenvironment.
Anderson K, Ryan N, Nedungadi D, Lamenza F, Swingler M, Siddiqui A, Satoskar A, Upadhaya P, Pietrzak M, Oghumu S., Free PMC Article | 08/27/2022 |
| High expression of TRIM24 predicts worse prognosis and promotes proliferation and metastasis of epithelial ovarian cancer. | High expression of TRIM24 predicts worse prognosis and promotes proliferation and metastasis of epithelial ovarian cancer.
Zhang L, Chen H, Ding B, Jiang W., Free PMC Article | 03/19/2022 |
| KAT6A Acetylation of SMAD3 Regulates Myeloid-Derived Suppressor Cell Recruitment, Metastasis, and Immunotherapy in Triple-Negative Breast Cancer. | KAT6A Acetylation of SMAD3 Regulates Myeloid-Derived Suppressor Cell Recruitment, Metastasis, and Immunotherapy in Triple-Negative Breast Cancer.
Yu B, Luo F, Sun B, Liu W, Shi Q, Cheng SY, Chen C, Chen G, Li Y, Feng H., Free PMC Article | 02/26/2022 |
| Overexpression of the TRIM24 E3 Ubiquitin Ligase is Linked to Genetic Instability and Predicts Unfavorable Prognosis in Prostate Cancer. | Overexpression of the TRIM24 E3 Ubiquitin Ligase is Linked to Genetic Instability and Predicts Unfavorable Prognosis in Prostate Cancer.
Höflmayer D, Fraune C, Hube-Magg C, Simon R, Schroeder C, Büscheck F, Möller K, Dum D, Weidemann S, Wittmer C, Schlomm T, Huland H, Heinzer H, Graefen M, Haese A, Sauter G, Burandt E, Clauditz TS, Steurer S, Minner S, Wilczak W, Polonski A. | 12/11/2021 |
| E3 ubiquitin ligase TRIM24 deficiency promotes NLRP3/caspase-1/IL-1beta-mediated pyroptosis in endometriosis. | E3 ubiquitin ligase TRIM24 deficiency promotes NLRP3/caspase-1/IL-1β-mediated pyroptosis in endometriosis.
Hang Y, Tan L, Chen Q, Liu Q, Jin Y. | 12/11/2021 |
| Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer. | Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer.
Shah VV, Duncan AD, Jiang S, Stratton SA, Allton KL, Yam C, Jain A, Krause PM, Lu Y, Cai S, Tu Y, Zhou X, Zhang X, Jiang Y, Carroll CL, Kang Z, Liu B, Shen J, Gagea M, Manu SM, Huo L, Gilcrease M, Powell RT, Guo L, Stephan C, Davies PJ, Parker-Thornburg J, Lozano G, Behringer RR, Piwnica-Worms H, Chang JT, Moulder SL, Barton MC., Free PMC Article | 10/16/2021 |
| Tripartite motif containing 24 regulates cell proliferation in colorectal cancer through YAP signaling. | Tripartite motif containing 24 regulates cell proliferation in colorectal cancer through YAP signaling.
Xie W, Zhang Y, Wang B, Hu Y, Zhan B, Wei F, Tang J, Lian J., Free PMC Article | 06/12/2021 |
| Long noncoding RNA ZFPM2AS1 promotes colorectal cancer progression by sponging miR137 to regulate TRIM24. | Long non‑coding RNA ZFPM2‑AS1 promotes colorectal cancer progression by sponging miR‑137 to regulate TRIM24.
Xiao M, Liang Z, Yin Z., Free PMC Article | 05/8/2021 |
| TRIM24 promotes stemness and invasiveness of glioblastoma cells via activating Sox2 expression. | TRIM24 promotes stemness and invasiveness of glioblastoma cells via activating Sox2 expression.
Zhang LH, Yin YH, Chen HZ, Feng SY, Liu JL, Chen L, Fu WL, Sun GC, Yu XG, Xu DG., Free PMC Article | 05/1/2021 |
| Knockdown of TRIM24 suppresses growth and induces apoptosis in acute myeloid leukemia through downregulation of Wnt/GSK-3beta/beta-catenin signaling. | Knockdown of TRIM24 suppresses growth and induces apoptosis in acute myeloid leukemia through downregulation of Wnt/GSK-3β/β-catenin signaling.
Li C, Xin H, Shi Y, Mu J. | 04/24/2021 |
| Trim24 and Trim33 Play a Role in Epigenetic Silencing of Retroviruses in Embryonic Stem Cells. | Trim24 and Trim33 Play a Role in Epigenetic Silencing of Retroviruses in Embryonic Stem Cells.
Margalit L, Strauss C, Tal A, Schlesinger S., Free PMC Article | 03/6/2021 |
| Downregulation of circEPSTI1 represses the proliferation and invasion of non-small cell lung cancer by inhibiting TRIM24 via miR-1248 upregulation. | Downregulation of circEPSTI1 represses the proliferation and invasion of non-small cell lung cancer by inhibiting TRIM24 via miR-1248 upregulation.
Yang T, Li M, Li H, Shi P, Liu J, Chen M. | 02/27/2021 |
| TRIM24 aggravates the progression of ovarian cancer through negatively regulating FOXM1 level. | TRIM24 aggravates the progression of ovarian cancer through negatively regulating FOXM1 level.
Zhou HE, Pan SS, Han H. | 02/13/2021 |
| TRIM24-RIP3 axis perturbation accelerates osteoarthritis pathogenesis. | TRIM24-RIP3 axis perturbation accelerates osteoarthritis pathogenesis.
Jeon J, Noh HJ, Lee H, Park HH, Ha YJ, Park SH, Lee H, Kim SJ, Kang HC, Eyun SI, Yang S, Kim YS., Free PMC Article | 12/12/2020 |
| NCK1-AS1 Increases Drug Resistance of Glioma Cells to Temozolomide by Modulating miR-137/TRIM24. | NCK1-AS1 Increases Drug Resistance of Glioma Cells to Temozolomide by Modulating miR-137/TRIM24.
Chen M, Cheng Y, Yuan Z, Wang F, Yang L, Zhao H. | 11/28/2020 |
| Tripartite motif-containing 24 protein (TRIM24) promotes clear cell renal cell carcinoma (ccRCC) progression through the Wnt/beta-catenin pathway. Nuclear factor erythroid 2-related factor 2 (Nrf2) promotes the transcription of TRIM24 in ccRCC. BMP8A/Nrf2/TRIM24-induced reactive oxygen species imbalance and Wnt pathway activation correlates with As2O3 resistance. | BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Yu YP, Cai LC, Wang XY, Cheng SY, Zhang DM, Jian WG, Wang TD, Yang JK, Yang KB, Zhang C., Free PMC Article | 06/6/2020 |
| demonstrate that the transcription co-factor and oncoprotein TRIM24 (tripartite motif-containing protein 24) is SUMOylated upon association with a specific histone modification signature, which regulates the transcription of genes involved in cell adhesion | A histone reader becomes the readout.
Musselman CA, Kutateladze TG., Free PMC Article | 03/7/2020 |
| the prognostic significance of Trim 24 in patients with solid carcinomas | Prognostic Implications of Tripartite Motif Containing 24 Expression Levels in Patients with Solid Tumors: A Systematic Review and Meta-Analysis.
He Y, Peng KW, Tang T, Deng L, Ye ZL, Luo MJ, Sun LY, You CX, Shao JY. | 12/14/2019 |
| TRIM24 appears to promote liver tumor development via AMPK signaling | TRIM24 promotes hepatocellular carcinoma progression via AMPK signaling.
Zhu Y, Zhao L, Shi K, Huang Z, Chen B. | 03/9/2019 |
| in response to RA, TRIM24 serves as an adapter linking RARalpha to the proteasome for its degradation. In addition, TRIM24 and the proteasome are recruited with RARalpha to the promoters of target genes and thus are inherently linked to RARalpha transcriptional activity. | TRIM24 mediates the interaction of the retinoic acid receptor alpha with the proteasome.
Carrier M, Lutzing R, Gaouar S, Rochette-Egly C. | 02/23/2019 |
| findings establish a new link between histone H3 acetylation and SUMOylation of the reader protein TRIM24, a functional connection that may bear on TRIM24's oncogenic function and may inform future studies of PTM cross-talk between histones and epigenetic regulators | Cross-talk between chromatin acetylation and SUMOylation of tripartite motif-containing protein 24 (TRIM24) impacts cell adhesion.
Appikonda S, Thakkar KN, Shah PK, Dent SYR, Andersen JN, Barton MC., Free PMC Article | 01/26/2019 |