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    APLN apelin [ Homo sapiens (human) ]

    Gene ID: 8862, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Apelin and the gut microbiome: Potential interaction in human MASLD.

    Apelin and the gut microbiome: Potential interaction in human MASLD.
    Effenberger M, Grander C, Hausmann B, Enrich B, Pjevac P, Zoller H, Tilg H.

    06/3/2024
    The regulatory role of the apelin/APJ axis in scarring: Identification of upstream and downstream mechanisms.

    The regulatory role of the apelin/APJ axis in scarring: Identification of upstream and downstream mechanisms.
    Shi N, Wang Y, Xia Z, Zhang J, Jia S, Jiao Y, Wang C, Wang X, Zhao J, Zhang J, Jiang D.

    04/16/2024
    Targeting the apelin system for the treatment of cardiovascular diseases.

    Targeting the apelin system for the treatment of cardiovascular diseases.
    Chapman FA, Maguire JJ, Newby DE, Davenport AP, Dhaun N., Free PMC Article

    01/13/2024
    Plasma Level of Apelin as a Promising Factor for Retinopathy of Prematurity.

    Plasma Level of Apelin as a Promising Factor for Retinopathy of Prematurity.
    Feng J, Liang G, Gao W, Li X, Wei L, Chang H, Zhang X, Tao Y.

    01/11/2024
    Circulating apelin, IL22RA2 and VEGF in pre-capillary pulmonary hypertension.

    Circulating apelin, IL22RA2 and VEGF in pre-capillary pulmonary hypertension.
    Csósza G, Szűcs G, Rozgonyi Z, Csoma B, Losonczy G, Müller V, Karlócai K, Lázár Z.

    12/27/2023
    The regulatory effects of the apelin/APJ system on depression: A prospective therapeutic target.

    The regulatory effects of the apelin/APJ system on depression: A prospective therapeutic target.
    Tian Y, Wang R, Liu L, Zhang W, Liu H, Jiang L, Jiang Y.

    11/20/2023
    Therapeutic potential of apelin and Elabela in cardiovascular disease.

    Therapeutic potential of apelin and Elabela in cardiovascular disease.
    Gao S, Chen H.

    10/4/2023
    Apelin and Visfatin Expression in Placental Tissue in Women With Preeclampsia and Overweight/Obesity.

    Apelin and Visfatin Expression in Placental Tissue in Women With Preeclampsia and Overweight/Obesity.
    Braga APDSX, Silva DM, de Farias Lelis D, Farias RE, Paraíso AF, Santos SHS, Martins AMEBL, Andrade JMO.

    09/15/2023
    Apelin is found in human sperm and testis and is raised in inflammatory pathological conditions.

    Apelin is found in human sperm and testis and is raised in inflammatory pathological conditions.
    Moretti E, Signorini C, Corsaro R, Noto D, AntonioTripodi S, Menchiari A, Micheli L, Ponchia R, Collodel G.

    08/11/2023
    Heterodimerization of apelin and opioid receptor-like 1 receptors mediates apelin-13-induced G protein biased signaling.

    Heterodimerization of apelin and opioid receptor-like 1 receptors mediates apelin-13-induced G protein biased signaling.
    Chen J, Wang Z, Zhang R, Yin H, Wang P, Wang C, Jiang Y.

    07/25/2023
    Rbpj Deficiency Disrupts Vascular Remodeling via Abnormal Apelin and Cdc42 (Cell Division Cycle 42) Activity in Brain Arteriovenous Malformation.

    Rbpj Deficiency Disrupts Vascular Remodeling via Abnormal Apelin and Cdc42 (Cell Division Cycle 42) Activity in Brain Arteriovenous Malformation.
    Adhicary S, Fanelli K, Nakisli S, Ward B, Pearce I, Nielsen CM., Free PMC Article

    05/28/2023
    Apelin as a Potential Regulator of Peak Athletic Performance.

    Apelin as a Potential Regulator of Peak Athletic Performance.
    Ligetvári R, Szokodi I, Far G, Csöndör É, Móra Á, Komka Z, Tóth M, Oláh A, Ács P., Free PMC Article

    05/22/2023
    Apelin/ELABELA-APJ system in cardiac hypertrophy: Regulatory mechanisms and therapeutic potential.

    Apelin/ELABELA-APJ system in cardiac hypertrophy: Regulatory mechanisms and therapeutic potential.
    Pang B, Jiang YR, Xu JY, Shao DX, Hao LY.

    05/8/2023
    Efficacy of serum apelin and galectin-3 as potential predictors of mortality in severe COVID-19 patients.

    Efficacy of serum apelin and galectin-3 as potential predictors of mortality in severe COVID-19 patients.
    Berber NK, Geçkil AA, Altan NÖ, Kıran TR, Otlu Ö, Erdem M, İn E.

    03/1/2023
    The Interaction of Apelin and FGFR1 Ameliorated the Kidney Fibrosis through Suppression of TGFbeta-Induced Endothelial-to-Mesenchymal Transition.

    The Interaction of Apelin and FGFR1 Ameliorated the Kidney Fibrosis through Suppression of TGFβ-Induced Endothelial-to-Mesenchymal Transition.
    Gao R, Wu Y, Yang Q, Chen L, Chen J, Wang B, Liu Z, Jin J, Li J, Wu G., Free PMC Article

    02/16/2023
    Apelin promotes osteosarcoma metastasis by upregulating PLOD2 expression via the Hippo signaling pathway and hsa_circ_0000004/miR-1303 axis.

    Apelin promotes osteosarcoma metastasis by upregulating PLOD2 expression via the Hippo signaling pathway and hsa_circ_0000004/miR-1303 axis.
    Trang NTN, Lai CY, Tsai HC, Huang YL, Liu SC, Tsai CH, Fong YC, Tzeng HE, Tang CH., Free PMC Article

    02/15/2023
    Evaluation of angiogenic apelin/apelin receptor axis in normal prostate, high grade prostatic intraepithelial neoplasia and prostatic adenocarcinoma.

    Evaluation of angiogenic apelin/apelin receptor axis in normal prostate, high grade prostatic intraepithelial neoplasia and prostatic adenocarcinoma.
    Soylu H, Unal B, Aksu K, Avci S, Caylan AE, Ustunel I I.

    01/14/2023
    APELIN IN HEART FAILURE.

    APELIN IN HEART FAILURE.
    Marczewski K, Gospodarczyk N, Gospodarczyk A, Widuch M, Tkocz M.

    12/17/2022
    Dysregulation of miR-204-5p/APLN axis affects malignant progression and cell stemness of esophageal cancer.

    Dysregulation of miR-204-5p/APLN axis affects malignant progression and cell stemness of esophageal cancer.
    Zhou Y, Xu R, Luo J, Li X, Zhong Y, Sun Z.

    12/10/2022
    Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models.

    Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models.
    Song K, Yang X, An G, Xia X, Zhao J, Xu X, Wan C, Liu T, Zheng Y, Ren S, Wang M, Chang G, Cronin SJF, Penninger JM, Jing T, Ou X, Rao S, Liu Z, Zhao XY., Free PMC Article

    12/10/2022
    Maternal serum Apelin 13 and APLN gene promoter variant -1860T > C in preeclampsia.

    Maternal serum Apelin 13 and APLN gene promoter variant -1860T > C in preeclampsia.
    Gandham R, Dayanand CD, Sheela SR, Kiranmayee P.

    11/26/2022
    Apelin levels in pregnant women with and without gestational diabetes mellitus: a collaborative systematic review and meta-analysis.

    Apelin levels in pregnant women with and without gestational diabetes mellitus: a collaborative systematic review and meta-analysis.
    Pérez-López FR, Wu JN, Yao L, López-Baena MT, Pérez-Roncero GR, Varikasuvu SR.

    11/19/2022
    Apelin is expressed throughout the human kidney, is elevated in chronic kidney disease & associates independently with decline in kidney function.

    Apelin is expressed throughout the human kidney, is elevated in chronic kidney disease & associates independently with decline in kidney function.
    Nyimanu D, Chapman FA, Gallacher PJ, Kuc RE, Williams TL, Newby DE, Maguire JJ, Davenport AP, Dhaun N., Free PMC Article

    11/19/2022
    Apelin-mediated deamidation of HMGA1 promotes tumorigenesis by enhancing SREBP1 activity and lipid synthesis.

    Apelin-mediated deamidation of HMGA1 promotes tumorigenesis by enhancing SREBP1 activity and lipid synthesis.
    Zhu Y, Yang Y, Bu H, Huang H, Chen H, Ran J, Qin L, Ni Y, Yao M, Song T, Li M, Yang Y, Guo T, Chao N, Liu Z, Li W, Zhang L., Free PMC Article

    11/12/2022
    Apelin Promotes Prostate Cancer Metastasis by Downregulating TIMP2 via Increases in miR-106a-5p Expression.

    Apelin Promotes Prostate Cancer Metastasis by Downregulating TIMP2 via Increases in miR-106a-5p Expression.
    Lin TH, Chang SL, Khanh PM, Trang NTN, Liu SC, Tsai HC, Chang AC, Lin JY, Chen PC, Liu JF, Guo JH, Liu CL, Wu HC, Tang CH., Free PMC Article

    11/5/2022
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