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    SOCS3 suppressor of cytokine signaling 3 [ Homo sapiens (human) ]

    Gene ID: 9021, updated on 30-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Exploring the clinical and cellular mechanisms of LncRNA-KCNQ1OT1/miR-29a-3p/SOCS3 molecular axis in cases of unexplained recurrent spontaneous abortion.

    Exploring the clinical and cellular mechanisms of LncRNA-KCNQ1OT1/miR-29a-3p/SOCS3 molecular axis in cases of unexplained recurrent spontaneous abortion.
    Huang YL, Huang GY, Chen H, Lv J, Wang J, Shen J, Zhao SY.

    04/26/2024
    Suppressor of cytokine signaling-3 expression and its regulation in relation to inflammation in Chronic Obstructive Pulmonary Disease.

    Suppressor of cytokine signaling-3 expression and its regulation in relation to inflammation in Chronic Obstructive Pulmonary Disease.
    Tinè M, Balestro E, Carpi S, Neri T, Biondini D, Conti M, Casara A, Bernardinello N, Cocconcelli E, Turato G, Baraldo S, Celi A, Spagnolo P, Cosio MG, Saetta M, Bazzan E., Free PMC Article

    03/29/2024
    SOCS3, Transcriptionally Activated by NR4A1, Induces Apoptosis and Extracellular Matrix Degradation of Vaginal Fibroblasts in Pelvic Organ Prolapse.

    SOCS3, Transcriptionally Activated by NR4A1, Induces Apoptosis and Extracellular Matrix Degradation of Vaginal Fibroblasts in Pelvic Organ Prolapse.
    Jin X, Hu Q, Qin M, Yin Y, Xia Z., Free PMC Article

    03/4/2024
    DNMTs-mediated SOCS3 methylation promotes the occurrence and development of AML.

    DNMTs-mediated SOCS3 methylation promotes the occurrence and development of AML.
    Zhang X, Zhang K, Zhang J, Chang W, Zhao Y, Suo X.

    02/21/2024
    Suppressor of Cytokine Signaling-3 Gene Polymorphisms and the Risk of Hepatocellular Carcinoma in Chronic Hepatitis C Patients in Egypt.

    Suppressor of Cytokine Signaling-3 Gene Polymorphisms and the Risk of Hepatocellular Carcinoma in Chronic Hepatitis C Patients in Egypt.
    El Sharnoby A, Bedair HM, Raia GYS, Hamed N, Sabry A, Khalaf FA, Abd Elhamed MR, Abdel-Samiee M., Free PMC Article

    01/16/2024
    Unleashing Breast Cancer Progression: miR-455-5p's Targeting of SOCS3 Drives Proliferation, Migration, and Invasion.

    Unleashing Breast Cancer Progression: miR-455-5p's Targeting of SOCS3 Drives Proliferation, Migration, and Invasion.
    Li X, Peng B, Li J, Tian M, He L.

    01/11/2024
    Resistin stimulates PC-3 prostate cancer cell growth through stimulation of SOCS3 and SOCS5 genes.

    Resistin stimulates PC-3 prostate cancer cell growth through stimulation of SOCS3 and SOCS5 genes.
    Liu CW, Peng HY, Siao AC, Tsuei YW, Lin YY, Shiah SG, Shih LJ, Yeh CC, Lee SW, Kao YH., Free PMC Article

    01/6/2024
    Enterovirus D68 infection upregulates SOCS3 expression to inhibit JAK-STAT3 signaling and antagonize the innate interferon response of the host.

    Enterovirus D68 infection upregulates SOCS3 expression to inhibit JAK-STAT3 signaling and antagonize the innate interferon response of the host.
    Zhang Y, Xu L, Zhang Z, Su X, Wang Z, Wang T., Free PMC Article

    11/1/2023
    DNA methylation at the suppressor of cytokine signaling 3 (SOCS3) gene influences height in childhood.

    DNA methylation at the suppressor of cytokine signaling 3 (SOCS3) gene influences height in childhood.
    Issarapu P, Arumalla M, Elliott HR, Nongmaithem SS, Sankareswaran A, Betts M, Sajjadi S, Kessler NJ, Bayyana S, Mansuri SR, Derakhshan M, Krishnaveni GV, Shrestha S, Kumaran K, Di Gravio C, Sahariah SA, Sanderson E, Relton CL, Ward KA, Moore SE, Prentice AM, Lillycrop KA, Fall CHD, Silver MJ, Chandak GR, EMPHASIS study group., Free PMC Article

    08/30/2023
    Characterization of the Roles of Suppressor of Cytokine Signaling-3 in Esophageal Carcinoma.

    Characterization of the Roles of Suppressor of Cytokine Signaling-3 in Esophageal Carcinoma.
    Yang X, Tian M, Lin Y, Li L, Sun X, Zhang Z, Kang M, Lin J.

    06/23/2023
    Gene variants and mRNA expression analysis of SOCS3 and its association with serum IL-4 levels in atopic diseases.

    Gene variants and mRNA expression analysis of SOCS3 and its association with serum IL-4 levels in atopic diseases.
    Hussain S, Rasool R, Shafi T, Gull A, Jan R, Bhat IA, Haq MG, Shah ZA.

    06/22/2023
    IL-6 prevents Th2 cell polarization by promoting SOCS3-dependent suppression of IL-2 signaling.

    IL-6 prevents Th2 cell polarization by promoting SOCS3-dependent suppression of IL-2 signaling.
    Bachus H, McLaughlin E, Lewis C, Papillion AM, Benveniste EN, Hill DD, Rosenberg AF, Ballesteros-Tato A, León B., Free PMC Article

    06/2/2023
    SOCS3 deregulation contributes to aberrant activation of the JAK/STAT pathway in precursor T-cell neoplasms.

    SOCS3 deregulation contributes to aberrant activation of the JAK/STAT pathway in precursor T-cell neoplasms.
    Lahera A, López-Nieva P, Alarcón H, Marín-Rubio JL, Cobos-Fernández MÁ, Fernández-Navarro P, Fernández AF, Vela-Martín L, Sastre I, Ruiz-García S, Llamas P, López-Lorenzo JL, Cornago J, Santos J, Fernández-Piqueras J, Villa-Morales M.

    05/5/2023
    Oncogenic role of microRNA-19b-3p-mediated SOCS3 in glioma through activation of JAK-STAT pathway.

    Oncogenic role of microRNA-19b-3p-mediated SOCS3 in glioma through activation of JAK-STAT pathway.
    Li T, Ge H, Yang Q, Wang J, Yin Q, Wang H, Hou G.

    04/19/2023
    SOCS3 as a potential driver of lung metastasis in colon cancer patients.

    SOCS3 as a potential driver of lung metastasis in colon cancer patients.
    Li X, Yang Z, Chen B, Gu L, Tian G, Sui X., Free PMC Article

    04/10/2023
    Obesity is associated with IL-6 gene polymorphisms rs1800795 and rs1800796 but not SOCS3 rs4969170.

    Obesity is associated with IL-6 gene polymorphisms rs1800795 and rs1800796 but not SOCS3 rs4969170.
    Koc G, Doran T, Uygur MM, Kirac D.

    03/16/2023
    Transcription factor B-MYB activates lncRNA CCAT1 and upregulates SOCS3 to promote chemoresistance in colorectal cancer.

    Transcription factor B-MYB activates lncRNA CCAT1 and upregulates SOCS3 to promote chemoresistance in colorectal cancer.
    Liu F, Wang Y, Cao Y, Wu Z, Ma D, Cai J, Sha J, Chen Q.

    03/14/2023
    The Relationship Between FoxP3 and SOCs3 Gene Expressions and Disease Activity in Rheumatoid Arthritis.

    The Relationship Between FoxP3 and SOCs3 Gene Expressions and Disease Activity in Rheumatoid Arthritis.
    Tawfeik AM, El-Dydamoni OA, Maghraby HM, Elshohat E, Seliem N, Abou Elhassan HA, Kassem EA, Anani HAA.

    02/28/2023
    Tissue levels of suppressor of cytokine signaling-3 (SOCS-3) in mycosis fungoides.

    Tissue levels of suppressor of cytokine signaling-3 (SOCS-3) in mycosis fungoides.
    Nada HR, Rashed LA, Salman OO, Abdallah NMA, Abdelhady MM., Free PMC Article

    02/23/2023
    Upregulated expression of FFAR2 and SOC3 genes is associated with gout.

    Upregulated expression of FFAR2 and SOC3 genes is associated with gout.
    Orji OC, López-Domínguez MB, Sandoval-Plata G, Guetta-Baranes T, Valdes AM, Doherty M, Morgan K, Abhishek A., Free PMC Article

    02/11/2023
    Alterations of SOCS1 and SOCS3 transcript levels, but not promoter methylation levels in subcutaneous adipose tissues in obese women.

    Alterations of SOCS1 and SOCS3 transcript levels, but not promoter methylation levels in subcutaneous adipose tissues in obese women.
    Emamgholipour S, Esmaeili F, Shabani M, Hasanpour SZ, Pilehvari M, Zabihi-Mahmoudabadi H, Motevasseli M, Shanaki M., Free PMC Article

    01/21/2023
    Modulation of SOCS3 Levels via STAT3 and Estrogen-ERalphap66 Signaling during Hepatitis E Virus Replication in Hepatocellular Carcinoma Cells.

    Modulation of SOCS3 Levels via STAT3 and Estrogen-ERαp66 Signaling during Hepatitis E Virus Replication in Hepatocellular Carcinoma Cells.
    Sooryanarain H, Heffron CL, Mahsoub HM, Hassebroek AM, Wang B, Tian D, Ahmed SA, Meng XJ., Free PMC Article

    10/22/2022
    Lack of association between SOCS3 and SOCS7 polymorphisms and psoriasis.

    Lack of association between SOCS3 and SOCS7 polymorphisms and psoriasis.
    Özçep M, Atsü N, Solak N, Çelik SK., Free PMC Article

    10/8/2022
    SOCS3 Regulates Dectin-2-Induced Inflammation in PBMCs of Diabetic Patients.

    SOCS3 Regulates Dectin-2-Induced Inflammation in PBMCs of Diabetic Patients.
    Haider MJA, Albaqsumi Z, Al-Mulla F, Ahmad R, Al-Rashed F., Free PMC Article

    10/8/2022
    Mendelian Randomization Analysis of the Association of SOCS3 Methylation with Abdominal Obesity.

    Mendelian Randomization Analysis of the Association of SOCS3 Methylation with Abdominal Obesity.
    Li Y, Liu X, Tu R, Hou J, Zhuang G., Free PMC Article

    10/1/2022
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