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    CD4 CD4 molecule [ Homo sapiens (human) ]

    Gene ID: 920, updated on 11-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Evaluating CD4 and Foxp3 mRNA Expression in Tissue Specimens of Celiac Disease and Colorectal Cancer Patients.

    Evaluating CD4 and Foxp3 mRNA Expression in Tissue Specimens of Celiac Disease and Colorectal Cancer Patients.
    Asri N, Nazemalhosseini Mojarad E, Taleghani MY, Houri H, Saeedi Niasar M, Rezaei-Tavirani M, Jahani-Sherafat S, Shahbazkhani A, Nikzamir A, Ehsani Ardakani MJ, Khodadost M, Rostami-Nejad M.

    02/29/2024
    The relationship between high ratios of CD4/FOXP3 and CD8/CD163 and the improved survivability of metastatic triple-negative breast cancer patients: a multicenter cohort study.

    The relationship between high ratios of CD4/FOXP3 and CD8/CD163 and the improved survivability of metastatic triple-negative breast cancer patients: a multicenter cohort study.
    Tenggara JB, Rachman A, Prihartono J, Rachmadi L, Panigoro SS, Heriyanto DS, Sutandyo N, Nasution IR, Rahadiati FB, Steven R, Betsy R, Juanputra S, Sudoyo AW., Free PMC Article

    02/7/2024
    Intermediate conformations of CD4-bound HIV-1 Env heterotrimers.

    Intermediate conformations of CD4-bound HIV-1 Env heterotrimers.
    Dam KA, Fan C, Yang Z, Bjorkman PJ., Free PMC Article

    12/5/2023
    HIV-1 Env trimers asymmetrically engage CD4 receptors in membranes.

    HIV-1 Env trimers asymmetrically engage CD4 receptors in membranes.
    Li W, Qin Z, Nand E, Grunst MW, Grover JR, Bess JW Jr, Lifson JD, Zwick MB, Tagare HD, Uchil PD, Mothes W., Free PMC Article

    12/5/2023
    Better Predictive Value of Lymphocyte Count and Hemoglobin for CD4 Level of HIV Patients.

    Better Predictive Value of Lymphocyte Count and Hemoglobin for CD4 Level of HIV Patients.
    Gao ZR, Yuan Z, Zhao CS, Zhao RG, Zhang Q.

    10/23/2023
    Stem-cell-like CD4[+] T cells prey on MHC class II-negative tumors.

    Stem-cell-like CD4(+) T cells prey on MHC class II-negative tumors.
    Veatch JR, Riddell SR.

    08/14/2023
    CD4+CD25+CD127[lo]FOXP3+ cell in food allergy: Does it predict anaphylaxis?

    CD4+CD25+CD127(lo)FOXP3+ cell in food allergy: Does it predict anaphylaxis?
    Erdem SB, Genel F, Nacaroglu HT, Karaman S, Karkıner CSU, Sürücü M, Can D.

    06/2/2023
    AP-2 Adaptor Complex-Dependent Enhancement of HIV-1 Replication by Nef in the Absence of the Nef/AP-2 Targets SERINC5 and CD4.

    AP-2 Adaptor Complex-Dependent Enhancement of HIV-1 Replication by Nef in the Absence of the Nef/AP-2 Targets SERINC5 and CD4.
    Olety B, Usami Y, Wu Y, Peters P, Göttlinger H., Free PMC Article

    03/2/2023
    Lack of Association between Common LAG3/CD4 Variants and Risk of Migraine.

    Lack of Association between Common LAG3/CD4 Variants and Risk of Migraine.
    García-Martín E, Navarro-Muñoz S, Ayuso P, Rodríguez C, Serrador M, Alonso-Navarro H, Calleja M, Navacerrada F, Turpín-Fenoll L, Recio-Bermejo M, García-Ruiz R, Millán-Pascual J, Plaza-Nieto JF, García-Albea E, Agúndez JAG, Jiménez-Jiménez FJ., Free PMC Article

    01/28/2023
    Association between LAG3/CD4 Genes Variants and Risk for Multiple Sclerosis.

    Association between LAG3/CD4 Genes Variants and Risk for Multiple Sclerosis.
    García-Martín E, Agúndez JAG, Gómez-Tabales J, Benito-León J, Millán-Pascual J, Díaz-Sánchez M, Calleja P, Turpín-Fenoll L, Alonso-Navarro H, García-Albea E, Plaza-Nieto JF, Jiménez-Jiménez FJ., Free PMC Article

    01/7/2023
    LAG3/CD4 Genes Variants and the Risk for Restless Legs Syndrome.

    LAG3/CD4 Genes Variants and the Risk for Restless Legs Syndrome.
    Jiménez-Jiménez FJ, Gómez-Tabales J, Alonso-Navarro H, Rodríguez C, Turpín-Fenoll L, Millán-Pascual J, Álvarez I, Pastor P, Calleja M, García-Ruiz R, Navarro-Muñoz S, Recio-Bermejo M, Plaza-Nieto JF, García-Albea E, García-Martín E, Agúndez JAG., Free PMC Article

    12/31/2022
    The level of urinary C4d is associated with disease progression in IgA nephropathy with glomerular crescentic lesions: a cohort study.

    The level of urinary C4d is associated with disease progression in IgA nephropathy with glomerular crescentic lesions: a cohort study.
    Wang Z, Jiang Y, Chen P, Wang J, Zhang X, Huang B, Zhou X, Shi S, Liu L, Lv J, Zhang H.

    10/29/2022
    Association between LAG3/CD4 gene variants and risk of Parkinson's disease.

    Association between LAG3/CD4 gene variants and risk of Parkinson's disease.
    García-Martín E, Pastor P, Gómez-Tabales J, Alonso-Navarro H, Alvarez I, Buongiorno M, Cerezo-Arias MLO, Aguilar M, Agúndez JAG, Jiménez-Jiménez FJ., Free PMC Article

    10/22/2022
    Covalent binding of human two-domain CD4 to an HIV-1 subtype C SOSIP.664 trimer modulates its structural dynamics.

    Covalent binding of human two-domain CD4 to an HIV-1 subtype C SOSIP.664 trimer modulates its structural dynamics.
    Tumba NL, Naicker P, Stoychev S, Killick MA, Owen GR, Papathanasopoulos MA.

    06/11/2022
    Genome-wide DNA methylation profiling identifies epigenetic changes in CD4+ and CD14+ cells of multiple sclerosis patients.

    Genome-wide DNA methylation profiling identifies epigenetic changes in CD4+ and CD14+ cells of multiple sclerosis patients.
    Kiselev I, Danilova L, Baulina N, Baturina O, Kabilov M, Boyko A, Kulakova O, Favorova O.

    05/21/2022
    Circulating miR-221/222 reduces CD4+ T cells by inhibiting CD4 expression in colorectal cancer.

    Circulating miR-221/222 reduces CD4+ T cells by inhibiting CD4 expression in colorectal cancer.
    Hu J, Zhang J, Yu M, Liu Z, Zou Y, Hong L, Zhang T, Sun J, Zheng M, Zhu X, Wang Z, Liu S.

    02/12/2022
    Molecular and Genetic Characterization of Natural Variants of HIV-1 Nef Gene from North India and its Functional Implication in Down-Regulation of MHC-I and CD-4.

    Molecular and Genetic Characterization of Natural Variants of HIV-1 Nef Gene from North India and its Functional Implication in Down-Regulation of MHC-I and CD-4.
    Singh J, Ronsard L, Pandey M, Kapoor R, Ramachandran VG, Banerjea AC.

    02/12/2022
    Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment.

    Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment.
    Wensel D, Williams S, Dixon DP, Ward P, McCormick P, Concha N, Stewart E, Hong X, Mazzucco C, Pal S, Ding B, Fellinger C, Krystal M.

    02/5/2022
    Lack of intrafollicular memory CD4 + T cells is predictive of early clinical failure in newly diagnosed follicular lymphoma.

    Lack of intrafollicular memory CD4 + T cells is predictive of early clinical failure in newly diagnosed follicular lymphoma.
    Mondello P, Fama A, Larson MC, Feldman AL, Villasboas JC, Yang ZZ, Galkin I, Svelolkin V, Postovalova E, Bagaev A, Ovcharov P, Varlamova A, Huet S, Tesson B, McGrath KR, Slager S, Link BK, Syrbu S, Novak AJ, Habermann TM, Witzig TE, Nowakowski GS, Salles G, Cerhan JR, Ansell SM., Free PMC Article

    02/5/2022
    CMV exposure drives long-term CD57+ CD4 memory T-cell inflation following allogeneic stem cell transplant.

    CMV exposure drives long-term CD57+ CD4 memory T-cell inflation following allogeneic stem cell transplant.
    Yeh AC, Varelias A, Reddy A, Barone SM, Olver SD, Chilson K, Onstad LE, Ensbey KS, Henden AS, Samson L, Jaeger CA, Bi T, Dahlman KB, Kim TK, Zhang P, Degli-Esposti MA, Newell EW, Jagasia MH, Irish JM, Lee SJ, Hill GR., Free PMC Article

    01/15/2022
    Serum CD4 Is Associated with the Infiltration of CD4(+)T Cells in the Tumor Microenvironment of Gastric Cancer.

    Serum CD4 Is Associated with the Infiltration of CD4(+)T Cells in the Tumor Microenvironment of Gastric Cancer.
    You Q, Fang T, Yin X, Wang Y, Yang Y, Zhang L, Xue Y., Free PMC Article

    01/1/2022
    Lost in Translation: Lack of CD4 Expression due to a Novel Genetic Defect.

    Lost in Translation: Lack of CD4 Expression due to a Novel Genetic Defect.
    Lisco A, Ye P, Wong CS, Pei L, Hsu AP, Mace EM, Orange JS, Lage SL, Ward AJ, Migueles SA, Connors M, Anderson MV, Buckner CM, Moir S, Rupert A, Dulau-Florea A, Ogbogu P, Timberlake D, Notarangelo LD, Pittaluga S, Abraham RS, Sereti I., Free PMC Article

    11/6/2021
    Increase of CD4+CD25highFoxP3+ cells impairs in vitro human microbicidal activity against Mycobacterium tuberculosis during latent and acute pulmonary tuberculosis.

    Increase of CD4+CD25highFoxP3+ cells impairs in vitro human microbicidal activity against Mycobacterium tuberculosis during latent and acute pulmonary tuberculosis.
    Stringari LL, Covre LP, da Silva FDC, de Oliveira VL, Campana MC, Hadad DJ, Palaci M, Salgame P, Dietze R, Gomes DCO, Ribeiro-Rodrigues R., Free PMC Article

    10/23/2021
    Monomeric human soluble CD4 dimerizes at physiological temperature: VTSAXS data based modeling and screening of retardant molecules.

    Monomeric human soluble CD4 dimerizes at physiological temperature: VTSAXS data based modeling and screening of retardant molecules.
    Dhiman K, Nath SK, Ashish.

    08/21/2021
    Identification of HIV-1 Envelope Mutations that Enhance Entry Using Macaque CD4 and CCR5.

    Identification of HIV-1 Envelope Mutations that Enhance Entry Using Macaque CD4 and CCR5.
    Roop JI, Cassidy NA, Dingens AS, Bloom JD, Overbaugh J., Free PMC Article

    04/17/2021
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