| Neurexin 2 p.G849D variant, implicated in Parkinson's disease, increases reactive oxygen species, and reduces cell viability and mitochondrial membrane potential in SH-SY5Y cells. | Neurexin 2 p.G849D variant, implicated in Parkinson's disease, increases reactive oxygen species, and reduces cell viability and mitochondrial membrane potential in SH-SY5Y cells.
Cuttler K, de Swardt D, Engelbrecht L, Kriel J, Cloete R, Bardien S. | 01/28/2023 |
| NRXN2 Possesses a Tumor Suppressor Potential via Inhibiting the Growth of Thyroid Cancer Cells. | NRXN2 Possesses a Tumor Suppressor Potential via Inhibiting the Growth of Thyroid Cancer Cells.
Ma C, Zhang Y., Free PMC Article | 02/5/2022 |
| A genetic interaction of NRXN2 with GABRE, SYT1 and CASK in migraine patients: a case-control study. | A genetic interaction of NRXN2 with GABRE, SYT1 and CASK in migraine patients: a case-control study.
Alves-Ferreira M, Quintas M, Sequeiros J, Sousa A, Pereira-Monteiro J, Alonso I, Neto JL, Lemos C., Free PMC Article | 06/19/2021 |
| Translational Inhibition of alpha-Neurexin 2. | Translational Inhibition of α-Neurexin 2.
Ding X, Meng S, Zhou J, Yang J, Li H, Zhou W., Free PMC Article | 11/21/2020 |
| Mutations in NRXN1 (c.2686C>T, p.Arg896Trp) and NRXN2 (c.3176G>A, p.Arg1059Gln) were found in a patient with early-onset epileptic encephalopathy and respiratory depression. | Mutations in NRXN1 and NRXN2 in a patient with early-onset epileptic encephalopathy and respiratory depression.
Rochtus AM, Trowbridge S, Goldstein RD, Sheidley BR, Prabhu SP, Haynes R, Kinney HC, Poduri AH., Free PMC Article | 04/4/2020 |
| The neurexins are a family of synaptic adhesion proteins encoded by paralogous genes that play key roles in synaptic function. | Neurexin gene family variants as risk factors for autism spectrum disorder.
Wang J, Gong J, Li L, Chen Y, Liu L, Gu H, Luo X, Hou F, Zhang J, Song R. | 08/10/2019 |
| NRXN2 gene had incomplete penetrance for autistic behavioral phenotype. | A de novo 921 Kb microdeletion at 11q13.1 including neurexin 2 in a boy with developmental delay, deficits in speech and language without autistic behaviors.
Yuan H, Li X, Wang Q, Yang W, Song J, Hu X, Shen Y. | 12/22/2018 |
| NRXN2 may play a part in early cortical synaptogenesis, but NRXNs could have diverse roles in development including axon guidance, and intercellular communication between proliferating cells and/or migrating neurons. | Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.
Harkin LF, Lindsay SJ, Xu Y, Alzu'bi A, Ferrara A, Gullon EA, James OG, Clowry GJ., Free PMC Article | 01/20/2018 |
| The rare variants in NRXN2 were significantly associated with smoking status. | The contribution of rare and common variants in 30 genes to risk nicotine dependence.
Yang J, Wang S, Yang Z, Hodgkinson CA, Iarikova P, Ma JZ, Payne TJ, Goldman D, Li MD., Free PMC Article | 08/6/2016 |
| Truncating mutations in NRXN2 is associated with autism spectrum disorders and schizophrenia | Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia.
Gauthier J, Siddiqui TJ, Huashan P, Yokomaku D, Hamdan FF, Champagne N, Lapointe M, Spiegelman D, Noreau A, Lafrenière RG, Fathalli F, Joober R, Krebs MO, DeLisi LE, Mottron L, Fombonne E, Michaud JL, Drapeau P, Carbonetto S, Craig AM, Rouleau GA., Free PMC Article | 11/19/2011 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesMaternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.
Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Nguyen TT, Christiansen L, Lidral AC, Murray JC. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.
Gratacòs M, Costas J, de Cid R, Bayés M, González JR, Baca-García E, de Diego Y, Fernández-Aranda F, Fernández-Piqueras J, Guitart M, Martín-Santos R, Martorell L, Menchón JM, Roca M, Sáiz-Ruiz J, Sanjuán J, Torrens M, Urretavizcaya M, Valero J, Vilella E, Estivill X, Carracedo A, Psychiatric Genetics Network Group. Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study.
Vega A, Salas A, Milne RL, Carracedo B, Ribas G, Ruibal A, de León AC, González-Hernández A, Benítez J, Carracedo A. | 11/5/2008 |