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    ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) [ Homo sapiens (human) ]

    Gene ID: 9429, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    NAT10-mediated mRNA N4-acetylcytidine modification of MDR1 and BCRP promotes breast cancer progression.

    NAT10-mediated mRNA N4-acetylcytidine modification of MDR1 and BCRP promotes breast cancer progression.
    Zhao CC, Sun X, Chen J, Geng BD., Free PMC Article

    04/11/2024
    ABCG2 Expression as a Potential Survival Predictor in Human Gliomas.

    ABCG2 Expression as a Potential Survival Predictor in Human Gliomas.
    Raguž M, Tarle M, Müller D, Tomasović-Lončarić Č, Chudy H, Marinović T, Chudy D., Free PMC Article

    04/2/2024
    Roles of breast cancer resistance protein and organic anion transporting polypeptide 2B1 in gastrointestinal toxicity induced by SN-38 under inflammatory conditions.

    Roles of breast cancer resistance protein and organic anion transporting polypeptide 2B1 in gastrointestinal toxicity induced by SN-38 under inflammatory conditions.
    Gulnaz A, Lee KR, Kang MJ, Chang JE, Chae YJ.

    04/2/2024
    ABCG2 polymorphisms and susceptibility to ARV-associated hepatotoxicity.

    ABCG2 polymorphisms and susceptibility to ARV-associated hepatotoxicity.
    Singh H, Dhotre K, Shyamveer, Choudhari R, Verma A, Mahajan SD, Ali N., Free PMC Article

    03/22/2024
    ABCG2 transporter reduces protein aggregation in cigarette smoke condensate-exposed A549 lung cancer cells.

    ABCG2 transporter reduces protein aggregation in cigarette smoke condensate-exposed A549 lung cancer cells.
    Ajenu EO, Seideneck AM, Pandellapalli E, Shinsky EM, Humphries CL, Aparicio NL, Sharma M, Marden JH, Krasilnikova MM., Free PMC Article

    03/13/2024
    Breast cancer resistance protein polymorphism ABCG2 c.421C>A (rs2231142) moderates the effect of valproate on lamotrigine trough concentrations in adults with epilepsy.

    Breast cancer resistance protein polymorphism ABCG2 c.421C>A (rs2231142) moderates the effect of valproate on lamotrigine trough concentrations in adults with epilepsy.
    Šušak Sporiš I, Božina N, Klarica Domjanović I, Sporiš D, Bašić S, Bašić I, Lovrić M, Ganoci L, Trkulja V.

    03/13/2024
    ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis.

    ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis.
    Chen C, Zhang Z, Liu C, Sun P, Liu P, Li X.

    03/11/2024
    Adipocyte-rich microenvironment promotes chemoresistance via upregulation of peroxisome proliferator-activated receptor gamma/ABCG2 in epithelial ovarian cancer.

    Adipocyte‑rich microenvironment promotes chemoresistance via upregulation of peroxisome proliferator‑activated receptor gamma/ABCG2 in epithelial ovarian cancer.
    Chen S, Liu Z, Wu H, Wang B, Ouyang Y, Liu J, Zheng X, Zhang H, Li X, Feng X, Li Y, Shen Y, Zhang H, Xiao B, Yu C, Deng W., Free PMC Article

    03/5/2024
    Carboranes as Potent Phenyl Mimetics: A Comparative Study on the Reversal of ABCG2-Mediated Drug Resistance by Carboranylquinazolines and Their Organic Isosteres.

    Carboranes as Potent Phenyl Mimetics: A Comparative Study on the Reversal of ABCG2-Mediated Drug Resistance by Carboranylquinazolines and Their Organic Isosteres.
    Stockmann P, Kuhnert L, Krajnović T, Mijatović S, Maksimović-Ivanić D, Honscha W, Hey-Hawkins E.

    01/26/2024
    GRP/GRPR signaling pathway aggravates hyperuricemia-induced renal inflammation and fibrosis via ABCG2-dependent mechanisms.

    GRP/GRPR signaling pathway aggravates hyperuricemia-induced renal inflammation and fibrosis via ABCG2-dependent mechanisms.
    Sun HL, Bian HG, Liu XM, Zhang H, Ying J, Yang H, Zu T, Cui GQ, Liao YF, Xu MF, Meng XM, Jin J.

    12/20/2023
    Association of ABCG2 Polymorphisms on Triple Negative Breast Cancer (TNBC) Susceptibility Risk.

    Association of ABCG2 Polymorphisms on Triple Negative Breast Cancer (TNBC) Susceptibility Risk.
    Hao Ing Y, Md Salleh MS, Yahya MM, Ankathil R, Abdul Aziz AA., Free PMC Article

    11/30/2023
    Molecular aspects of ABCB1 and ABCG2 in Gallbladder cancer and its clinical relevance.

    Molecular aspects of ABCB1 and ABCG2 in Gallbladder cancer and its clinical relevance.
    Nimisha, Saluja SS, Sharma AK, Nekarakanti PK, Apurva, Kumar A, Sattar RSA, Anjum H, Batra VV, Husain SA.

    09/27/2023
    Changes in Expression and Function of Placental and Intestinal P-gp and BCRP Transporters during Pregnancy.

    Changes in Expression and Function of Placental and Intestinal P-gp and BCRP Transporters during Pregnancy.
    Szatmári P, Ducza E., Free PMC Article

    09/13/2023
    ABCG2 Gene Polymorphisms May Affect the Bleeding Risk in Patients on Apixaban and Rivaroxaban.

    ABCG2 Gene Polymorphisms May Affect the Bleeding Risk in Patients on Apixaban and Rivaroxaban.
    Kim H, Song TJ, Yee J, Kim DH, Park J, Gwak HS., Free PMC Article

    08/31/2023
    The net electrostatic potential and hydration of ABCG2 affect substrate transport.

    The net electrostatic potential and hydration of ABCG2 affect substrate transport.
    Gose T, Aitken HM, Wang Y, Lynch J, Rampersaud E, Fukuda Y, Wills M, Baril SA, Ford RC, Shelat A, Mara MLO, Schuetz JD., Free PMC Article

    08/25/2023
    In vitro identification of decreased function phenotype ABCG2 variants.

    In vitro identification of decreased function phenotype ABCG2 variants.
    Suominen L, Sjöstedt N, Vellonen KS, Gynther M, Auriola S, Kidron H.

    08/19/2023
    ABCB1 and ABCG2 Regulation at the Blood-Brain Barrier: Potential New Targets to Improve Brain Drug Delivery.

    ABCB1 and ABCG2 Regulation at the Blood-Brain Barrier: Potential New Targets to Improve Brain Drug Delivery.
    Schulz JA, Hartz AMS, Bauer B., Free PMC Article

    08/17/2023
    Genetic polymorphisms and decreased protein expression of ABCG2 urate transporters are associated with susceptibility to gout, disease severity and renal-overload hyperuricemia.

    Genetic polymorphisms and decreased protein expression of ABCG2 urate transporters are associated with susceptibility to gout, disease severity and renal-overload hyperuricemia.
    Pálinkás M, Szabó E, Kulin A, Mózner O, Rásonyi R, Juhász P, Nagy K, Várady G, Vörös D, Zámbó B, Sarkadi B, Poór G., Free PMC Article

    08/3/2023
    The impact of ABCB1, CYP3A4/5 and ABCG2 gene polymorphisms on rivaroxaban trough concentrations and bleeding events in patients with non-valvular atrial fibrillation.

    The impact of ABCB1, CYP3A4/5 and ABCG2 gene polymorphisms on rivaroxaban trough concentrations and bleeding events in patients with non-valvular atrial fibrillation.
    Wu T, Wu S, Li L, Xiang J, Wang N, Chen W, Zhang J., Free PMC Article

    07/12/2023
    Up-regulation of ABCG2 by MYBL2 deletion drives Chlorin e6-mediated photodynamic therapy resistance in colorectal cancer.

    Up-regulation of ABCG2 by MYBL2 deletion drives Chlorin e6-mediated photodynamic therapy resistance in colorectal cancer.
    Hui YJ, Chen H, Peng XC, Li LG, Di MJ, Liu H, Hu XH, Yang Y, Zhao KL, Li TF, Yu TT, Wang WX.

    07/6/2023
    MiR-548 K regulatory effect on the ABCG2 gene expression in MDR breast cancer cells.

    MiR-548 K regulatory effect on the ABCG2 gene expression in MDR breast cancer cells.
    Saberiyan M, Ghasemi Z, Yaghoobi H., Free PMC Article

    06/13/2023
    ABCG2 plays a central role in the dysregulation of 25-hydrovitamin D in Crohn's disease.

    ABCG2 plays a central role in the dysregulation of 25-hydrovitamin D in Crohn's disease.
    Peng J, Song X, Zhu F, Zhang C, Xia J, Zou D, Liu J, Yin F, Yin L, Guo H, Liu J.

    06/7/2023
    The frequency of major ABCG2, SLCO1B1 and CYP2C9 variants in Asian, Native Hawaiian and Pacific Islander women subgroups: implications for personalized statins dosing.

    The frequency of major ABCG2, SLCO1B1 and CYP2C9 variants in Asian, Native Hawaiian and Pacific Islander women subgroups: implications for personalized statins dosing.
    Alrajeh K, AlAzzeh O, Roman Y., Free PMC Article

    06/5/2023
    Role of the Abcg2 Transporter in Secretion into Milk of the Anthelmintic Clorsulon: Interaction with Ivermectin.

    Role of the Abcg2 Transporter in Secretion into Milk of the Anthelmintic Clorsulon: Interaction with Ivermectin.
    Blanco-Paniagua E, Álvarez-Fernández L, Rodríguez-Alonso A, Millán-Garcia A, Álvarez AI, Merino G., Free PMC Article

    05/19/2023
    A meta-analysis and experimental data for multidrug resistance genes in breast cancer.

    A meta-analysis and experimental data for multidrug resistance genes in breast cancer.
    Zaib S, Tahir S, Masood N, Hameed A, Azra Y., Free PMC Article

    05/12/2023
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