| Targeting YAP/TAZ mechanosignaling to ameliorate stiffness-induced Schlemm's canal cell pathobiology. | Targeting YAP/TAZ mechanosignaling to ameliorate stiffness-induced Schlemm's canal cell pathobiology.
Li H, Kuhn M, Kelly RA, Singh A, Palanivel KK, Salama I, De Ieso ML, Stamer WD, Ganapathy PS, Herberg S. | 02/13/2024 |
| Wnt16 Promotes Vascular Smooth Muscle Contractile Phenotype and Function via Taz (Wwtr1) Activation in Male LDLR-/- Mice. | Wnt16 Promotes Vascular Smooth Muscle Contractile Phenotype and Function via Taz (Wwtr1) Activation in Male LDLR-/- Mice.
Behrmann A, Zhong D, Li L, Xie S, Mead M, Sabaeifard P, Goodarzi M, Lemoff A, Kozlitina J, Towler DA., | 01/17/2024 |
| TAZ stimulates exercise-induced muscle satellite cell activation via Pard3-p38 MAPK-TAZ signalling axis. | TAZ stimulates exercise-induced muscle satellite cell activation via Pard3-p38 MAPK-TAZ signalling axis.
Kim KM, Yoo GD, Heo W, Oh HT, Park J, Shin S, Do Y, Jeong MG, Hwang ES, Hong JH., Free PMC Article | 01/6/2024 |
| TAZ facilitates breast tumor growth by promoting an immune-suppressive tumor microenvironment. | TAZ facilitates breast tumor growth by promoting an immune-suppressive tumor microenvironment.
Gershoni A, Hassin O, Nataraj NB, Baruch S, Avioz-Seligman A, Pirona AC, Fellus-Alyagor L, Meir Salame T, Mukherjee S, Mallel G, Yarden Y, Aylon Y, Oren M., Free PMC Article | 12/21/2023 |
| Genetic interactions between polycystin-1 and Wwtr1 in osteoblasts define a novel mechanosensing mechanism regulating bone formation in mice. | Genetic interactions between polycystin-1 and Wwtr1 in osteoblasts define a novel mechanosensing mechanism regulating bone formation in mice.
Xiao Z, Cao L, Smith MD, Li H, Li W, Smith JC, Quarles LD., Free PMC Article | 11/15/2023 |
| Regulation of follicular activation signaling pathways by in vitro inhibition of YAP/TAZ activity in mouse ovaries. | Regulation of follicular activation signaling pathways by in vitro inhibition of YAP/TAZ activity in mouse ovaries.
Devos M, Dias Nunes J, Donfack Jiatsa N, Demeestere I., Free PMC Article | 09/23/2023 |
| Vascular smooth muscle-specific YAP/TAZ deletion triggers aneurysm development in mouse aorta. | Vascular smooth muscle-specific YAP/TAZ deletion triggers aneurysm development in mouse aorta.
Arévalo Martínez M, Ritsvall O, Bastrup JA, Celik S, Jakobsson G, Daoud F, Winqvist C, Aspberg A, Rippe C, Maegdefessel L, Schiopu A, Jepps TA, Holmberg J, Swärd K, Albinsson S., Free PMC Article | 09/13/2023 |
| Loss of TAZ after YAP deletion severely impairs foregut development and worsens cholestatic hepatocellular injury. | Loss of TAZ after YAP deletion severely impairs foregut development and worsens cholestatic hepatocellular injury.
Gabdulkhakova A, Krutsenko Y, Zhu J, Liu S, Poddar M, Singh S, Ma X, Nejak-Bowen K, Monga SPS, Molina LM., Free PMC Article | 08/11/2023 |
| Emerging Roles of YAP/TAZ in Tooth and Surrounding: from Development to Regeneration. | Emerging Roles of YAP/TAZ in Tooth and Surrounding: from Development to Regeneration.
Yang S, Huang F, Zhang F, Sheng X, Fan W, Dissanayaka WL. | 08/3/2023 |
| A YAP/TAZ-CD54 axis is required for CXCR2-CD44- tumor-specific neutrophils to suppress gastric cancer. | A YAP/TAZ-CD54 axis is required for CXCR2-CD44- tumor-specific neutrophils to suppress gastric cancer.
Nie P, Zhang W, Meng Y, Lin M, Guo F, Zhang H, Tong Z, Wang M, Chen F, An L, Tang Y, Han Y, Yu R, Wang W, Xu Y, Wei L, Zhou Z, Jiao S., Free PMC Article | 06/30/2023 |
| Denervation Drives YAP/TAZ Activation in Muscular Fibro/Adipogenic Progenitors. | Denervation Drives YAP/TAZ Activation in Muscular Fibro/Adipogenic Progenitors.
Gallardo FS, Córdova-Casanova A, Bock-Pereda A, Rebolledo DL, Ravasio A, Casar JC, Brandan E., Free PMC Article | 03/31/2023 |
| Transcription Factors YAP/TAZ and SRF Cooperate To Specify Renal Myofibroblasts in the Developing Mouse Kidney. | Transcription Factors YAP/TAZ and SRF Cooperate To Specify Renal Myofibroblasts in the Developing Mouse Kidney.
Drake KA, Chaney C, Patel M, Das A, Bittencourt J, Cohn M, Carroll TJ., Free PMC Article | 01/28/2023 |
| Loss-of-function of the hippo transducer TAZ reduces mammary tumor growth through a myeloid-derived suppressor cell-dependent mechanism. | Loss-of-function of the hippo transducer TAZ reduces mammary tumor growth through a myeloid-derived suppressor cell-dependent mechanism.
Shen H, Zhang Y, Kramer ED, Katsuta E, Wan Y, Chen Y, Wang J, Zhang Y, Matsuzaki J, Frangou C, Abrams SI, Zhang J., Free PMC Article | 01/28/2023 |
| CD133-Src-TAZ signaling stimulates ductal fibrosis following DDC diet-induced liver injury. | CD133-Src-TAZ signaling stimulates ductal fibrosis following DDC diet-induced liver injury.
Oh HT, Heo W, Yoo GD, Kim KM, Hwang JH, Hwang ES, Ko J, Ko YG, Hong JH. | 12/24/2022 |
| Role of smooth muscle YAP and TAZ in protection against phenotypic modulation, inflammation, and aneurysm development. | Role of smooth muscle YAP and TAZ in protection against phenotypic modulation, inflammation, and aneurysm development.
Daoud F, Arévalo Martínez M, Holst J, Holmberg J, Albinsson S, Swärd K. | 12/17/2022 |
| Hippo-TAZ signaling is the master regulator of the onset of triple-negative basal-like breast cancers. | Hippo-TAZ signaling is the master regulator of the onset of triple-negative basal-like breast cancers.
Soyama H, Nishio M, Otani J, Sakuma T, Takao S, Hara S, Masuda T, Mimori K, Toyokuni S, Lydon JP, Nakao K, Nishina H, Fukumoto T, Maehama T, Suzuki A., Free PMC Article | 07/30/2022 |
| TAZ-induced Cybb contributes to liver tumor formation in non-alcoholic steatohepatitis. | TAZ-induced Cybb contributes to liver tumor formation in non-alcoholic steatohepatitis.
Wang X, Zeldin S, Shi H, Zhu C, Saito Y, Corey KE, Osganian SA, Remotti HE, Verna EC, Pajvani UB, Schwabe RF, Tabas I., Free PMC Article | 07/23/2022 |
| YAP and TAZ in Vascular Smooth Muscle Confer Protection Against Hypertensive Vasculopathy. | YAP and TAZ in Vascular Smooth Muscle Confer Protection Against Hypertensive Vasculopathy.
Daoud F, Arévalo Martinez M, Holmberg J, Alajbegovic A, Ali N, Rippe C, Swärd K, Albinsson S., Free PMC Article | 07/9/2022 |
| Loss of Yap/Taz in cardiac fibroblasts attenuates adverse remodelling and improves cardiac function. | Loss of Yap/Taz in cardiac fibroblasts attenuates adverse remodelling and improves cardiac function.
Mia MM, Cibi DM, Ghani SABA, Singh A, Tee N, Sivakumar V, Bogireddi H, Cook SA, Mao J, Singh MK. | 07/2/2022 |
| Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex. | Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex.
Terry BK, Park R, Cho SH, Crino PB, Kim S., Free PMC Article | 07/2/2022 |
| The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease. | The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease.
Cigliano A, Zhang S, Ribback S, Steinmann S, Sini M, Ament CE, Utpatel K, Song X, Wang J, Pilo MG, Berger F, Wang H, Tao J, Li X, Pes GM, Mancarella S, Giannelli G, Dombrowski F, Evert M, Calvisi DF, Chen X, Evert K., Free PMC Article | 06/11/2022 |
| A Critical Balance Between PAX8 and the Hippo Mediator TAZ Determines Sodium/Iodide Symporter Expression and Function. | A Critical Balance Between PAX8 and the Hippo Mediator TAZ Determines Sodium/Iodide Symporter Expression and Function.
Fernández-Méndez C, Santisteban P. | 05/14/2022 |
| Myofibroblast YAP/TAZ activation is a key step in organ fibrogenesis. | Myofibroblast YAP/TAZ activation is a key step in organ fibrogenesis.
He X, Tolosa MF, Zhang T, Goru SK, Ulloa Severino L, Misra PS, McEvoy CM, Caldwell L, Szeto SG, Gao F, Chen X, Atin C, Ki V, Vukosa N, Hu C, Zhang J, Yip C, Krizova A, Wrana JL, Yuen DA., Free PMC Article | 04/16/2022 |
| TAZ as a novel regulator of oxidative damage in decidualization via Nrf2/ARE/Foxo1 pathway. | TAZ as a novel regulator of oxidative damage in decidualization via Nrf2/ARE/Foxo1 pathway.
Yu HF, Zheng LW, Yang ZQ, Wang YS, Wang TT, Yue ZP, Guo B., Free PMC Article | 04/16/2022 |
| TAZ links exercise to mitochondrial biogenesis via mitochondrial transcription factor A. | TAZ links exercise to mitochondrial biogenesis via mitochondrial transcription factor A.
Hwang JH, Kim KM, Oh HT, Yoo GD, Jeong MG, Lee H, Park J, Jeong K, Kim YK, Ko YG, Hwang ES, Hong JH., Free PMC Article | 02/26/2022 |