| DLGAP5 promotes lung adenocarcinoma growth via upregulating PLK1 and serves as a therapeutic target. | DLGAP5 promotes lung adenocarcinoma growth via upregulating PLK1 and serves as a therapeutic target.
Chen M, Zhang S, Wang F, He J, Jiang W, Zhang L., Free PMC Article | 02/29/2024 |
| DLGAP5 triggers proliferation and metastasis of bladder cancer by stabilizing E2F1 via USP11. | DLGAP5 triggers proliferation and metastasis of bladder cancer by stabilizing E2F1 via USP11.
Zhou F, Deng Z, Shen D, Lu M, Li M, Yu J, Xiao Y, Wang G, Qian K, Ju L, Wang X. | 02/23/2024 |
| circ_0058063 promotes breast cancer progression by upregulating DLGAP5 via sponging miR-557. | circ_0058063 promotes breast cancer progression by upregulating DLGAP5 via sponging miR-557.
Zhu K, Yi C, Tong C., Free PMC Article | 02/2/2024 |
| DLGAP5 promotes gallbladder cancer migration and tumor-associated macrophage M2 polarization by activating cAMP. | DLGAP5 promotes gallbladder cancer migration and tumor-associated macrophage M2 polarization by activating cAMP.
Huang J, Zheng M, Li Y, Xu D, Tian D., Free PMC Article | 11/2/2023 |
| DLGAP5 knockdown inactivates the Wnt/beta-catenin signal to repress endometrial cancer cell malignant activities. | DLGAP5 knockdown inactivates the Wnt/β-catenin signal to repress endometrial cancer cell malignant activities.
Chen R, Liu J, Hu J, Li C, Liu Y, Pan W. | 02/15/2023 |
| High Expression of DLGAP5 Indicates Poor Prognosis and Immunotherapy in Lung Adenocarcinoma and Promotes Proliferation through Regulation of the Cell Cycle. | High Expression of DLGAP5 Indicates Poor Prognosis and Immunotherapy in Lung Adenocarcinoma and Promotes Proliferation through Regulation of the Cell Cycle.
Tang X, Zhou H, Liu Y., Free PMC Article | 02/4/2023 |
| Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome. | Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome.
Deng Y, Li H, Song Y, Cen J, Zhang Y, Sui Y, Cui D, Li TC, Xu Y, Wang CC, Chung PWJ, Tang T., Free PMC Article | 04/9/2022 |
| Screening and identification of LMNB1 and DLGAP5, two key biomarkers in gliomas. | Screening and identification of LMNB1 and DLGAP5, two key biomarkers in gliomas.
Zhou D, Wang M, Zhang Y, Wang K, Zhao M, Wang Y, Wang X, Yu R, Zhou X., Free PMC Article | 12/25/2021 |
| Pan-cancer analysis and experiments with cell lines reveal that the slightly elevated expression of DLGAP5 is involved in clear cell renal cell carcinoma progression. | Pan-cancer analysis and experiments with cell lines reveal that the slightly elevated expression of DLGAP5 is involved in clear cell renal cell carcinoma progression.
Feng Y, Li F, Yan J, Guo X, Wang F, Shi H, Du J, Zhang H, Gao Y, Li D, Yao Y, Hu W, Han J, Zhang M, Ding R, Wang X, Huang C, Zhang J. | 12/18/2021 |
| The expression of hepatoma upregulated protein in human endometrium during the menstrual cycle. | The expression of hepatoma upregulated protein in human endometrium during the menstrual cycle.
Takahashi A, Yamanaka A, Takebayashi A, Kimura F, Murakami T. | 10/30/2021 |
| Ran-GTP Is Non-essential to Activate NuMA for Mitotic Spindle-Pole Focusing but Dynamically Polarizes HURP Near Chromosomes. | Ran-GTP Is Non-essential to Activate NuMA for Mitotic Spindle-Pole Focusing but Dynamically Polarizes HURP Near Chromosomes.
Tsuchiya K, Hayashi H, Nishina M, Okumura M, Sato Y, Kanemaki MT, Goshima G, Kiyomitsu T. | 09/4/2021 |
| Spindle-Length-Dependent HURP Localization Allows Centrosomes to Control Kinetochore-Fiber Plus-End Dynamics. | Spindle-Length-Dependent HURP Localization Allows Centrosomes to Control Kinetochore-Fiber Plus-End Dynamics.
Dudka D, Castrogiovanni C, Liaudet N, Vassal H, Meraldi P. | 09/5/2020 |
| DLG7/DLGAP5 represents a potential biomarker for colorectal cancer. | Prognostic value of DLGAP5 in colorectal cancer.
Branchi V, García SA, Radhakrishnan P, Győrffy B, Hissa B, Schneider M, Reißfelder C, Schölch S. | 01/18/2020 |
| DLGAP5 has a unique function in stabilizing spindle formation and surviving microtubule assault from docetaxel, in an androgen-regulated cell cycle system. | A functional genomics screen reveals a strong synergistic effect between docetaxel and the mitotic gene DLGAP5 that is mediated by the androgen receptor.
Hewit K, Sandilands E, Martinez RS, James D, Leung HY, Bryant DM, Shanks E, Markert EK., Free PMC Article | 12/14/2019 |
| positive expression of DLGAP5 in prostate cancer tissues correlates with poor prognosis of patients and has a role in castration-resistant prostate cancer cell growth and migration. | Identification of new octamer transcription factor 1-target genes upregulated in castration-resistant prostate cancer.
Yamamoto S, Takayama KI, Obinata D, Fujiwara K, Ashikari D, Takahashi S, Inoue S., Free PMC Article | 11/16/2019 |
| Elevated NEK2, DLGAP5 and ECT2 expression was negatively correlated with both overall survival (OS) and relapse-free survival (RFS). | Genome-scale analysis identifies NEK2, DLGAP5 and ECT2 as promising diagnostic and prognostic biomarkers in human lung cancer.
Shi YX, Yin JY, Shen Y, Zhang W, Zhou HH, Liu ZQ., Free PMC Article | 03/9/2019 |
| HURP recruits TACC3 to regulate K-fiber formation and support chromosome congression. | The microtubule-associated protein HURP recruits the centrosomal protein TACC3 to regulate K-fiber formation and support chromosome congression.
Zhang Y, Tan L, Yang Q, Li C, Liou YC., Free PMC Article | 03/9/2019 |
| Study provides evidence that downregulation of NUSAP1 can inhibit the proliferation, migration, and invasion of IBC cells by regulating CDK1 and DLGAP5 expression and enhances the drug susceptibility to E-ADM. | Nucleolar and Spindle Associated Protein 1 (NUSAP1) Inhibits Cell Proliferation and Enhances Susceptibility to Epirubicin In Invasive Breast Cancer Cells by Regulating Cyclin D Kinase (CDK1) and DLGAP5 Expression.
Zhang X, Pan Y, Fu H, Zhang J., Free PMC Article | 02/2/2019 |
| The bioinformatic analysis suggests that HURP promotes carcinogenesis in multiple manners. Taken together, we revealed the prognostic value of HURP in nonsmall cell lung cancer (NSCLC)patients and HURP may be a potential therapeutic target for NSCLC. | Prognostic and predictive value of HURP in non‑small cell lung cancer.
Wang Q, Chen Y, Feng H, Zhang B, Wang H., Free PMC Article | 08/25/2018 |
| Data provide evidence for the involvement of HURP protein in the modulation of prostate cancer cell resistance to gamma irradiation via mechanism mediated by the ubiquitination of ATM and p53. | Elevated Expression of Hepatoma Up-Regulated Protein Inhibits γ-Irradiation-Induced Apoptosis of Prostate Cancer Cells.
Hassan M, El Khattouti A, Ejaeidi A, Ma T, Day WA, Espinoza I, Vijayakumar S, Gomez CR. | 12/17/2016 |
| Aurora-A/HURP relays cell transforming signal to NF-kappaB, and the HURP/NF-kappaB complex is engaged in the regulation of cyclin E1 expression. | The involvement of nuclear factor-κappaB in the nuclear targeting and cyclin E1 upregulating activities of hepatoma upregulated protein.
Chen JM, Chiu SC, Wei TY, Lin SY, Chong CM, Wu CC, Huang JY, Yang ST, Ku CF, Hsia JY, Yu CT. | 08/15/2015 |
| Detection of urinary HURP RNA is a useful for early detection of bladder cancer and bilharzial bladder cancer. | Evaluation of urinary HURP mRNA as a marker for detection of bladder cancer: relation to bilharziasis.
Eissa S, Matboli M, Mansour A, Mohamed S, Awad N, Kotb YM. | 10/11/2014 |
| expression of DLG7, a hypoxia-controlled gene, holds prognostic potential in high-risk CaP; this also demonstrates that variation of oxygen tension may constitute a tool for identification of novel biomarkers for CaP. | Prognostic value of discs large homolog 7 transcript levels in prostate cancer.
Gomez CR, Kosari F, Munz JM, Schreiber CA, Knutson GJ, Ida CM, El Khattouti A, Karnes RJ, Cheville JC, Vasmatzis G, Vuk-Pavlović S., Free PMC Article | 10/11/2014 |
| The expression of DLGAP5 is regulated by methylation; the up-regulation of DLGAP5 contributes to hepatocellular carcinoma tumorigenesis by promoting cell proliferation. | Silencing of DLGAP5 by siRNA significantly inhibits the proliferation and invasion of hepatocellular carcinoma cells.
Liao W, Liu W, Yuan Q, Liu X, Ou Y, He S, Yuan S, Qin L, Chen Q, Nong K, Mei M, Huang J., Free PMC Article | 09/13/2014 |
| RNA purification using functionalized MNPs was 97%. CONCLUSIONS: The developed colorimetric HURP RNA AuNP assay is sensitive, simple, and can aid noninvasive diagnosis of bladder cancer | Direct detection of unamplified hepatoma upregulated protein RNA in urine using gold nanoparticles for bladder cancer diagnosis.
Eissa S, Shawky SM, Matboli M, Mohamed S, Azzazy HM. | 08/9/2014 |