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    ODAM odontogenic, ameloblast associated [ Homo sapiens (human) ]

    Gene ID: 54959, updated on 25-Jan-2022

    Summary

    Official Symbol
    ODAMprovided by HGNC
    Official Full Name
    odontogenic, ameloblast associatedprovided by HGNC
    Primary source
    HGNC:HGNC:26043
    See related
    Ensembl:ENSG00000109205 MIM:614843; AllianceGenome:HGNC:26043
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    APIN
    Summary
    Involved in several processes, including positive regulation of GTPase activity; positive regulation of epithelial cell proliferation involved in wound healing; and positive regulation of macromolecule metabolic process. Located in several cellular components, including extracellular space; mitotic spindle; and nucleoplasm. [provided by Alliance of Genome Resources, Nov 2021]
    Expression
    Restricted expression toward salivary gland (RPKM 78.4) See more
    Orthologs
    NEW
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    Genomic context

    See ODAM in Genome Data Viewer
    Location:
    4q13.3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109.20211119 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (70195725..70204576)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (71061442..71070293)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene proline rich 27 Neighboring gene uncharacterized LOC105377270 Neighboring gene follicular dendritic cell secreted protein Neighboring gene casein kappa

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ20513

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell periphery IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
     
    located_in extracellular region TAS
    Traceable Author Statement
    more info
     
    located_in extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitotic spindle IDA
    Inferred from Direct Assay
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in supramolecular fiber IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    odontogenic ameloblast-associated protein
    Names
    odontogenic, ameloblast asssociated

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001385579.1NP_001372508.1  odontogenic ameloblast-associated protein isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC105347
      Conserved Domains (1) summary
      pfam15424
      Location:16263
      ODAM; Odontogenic ameloblast-associated family
    2. NM_017855.4NP_060325.3  odontogenic ameloblast-associated protein isoform 1 precursor

      See identical proteins and their annotated locations for NP_060325.3

      Status: VALIDATED

      Source sequence(s)
      AC105347
      Consensus CDS
      CCDS3536.2
      UniProtKB/Swiss-Prot
      A1E959
      Related
      ENSP00000507531.1, ENST00000683306.1
      Conserved Domains (1) summary
      pfam15424
      Location:16279
      ODAM; Odontogenic ameloblast-associated family

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

      Range
      70195725..70204576
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017008331.1XP_016863820.1  odontogenic ameloblast-associated protein isoform X2

      Related
      ENSP00000423070.2, ENST00000510709.6
      Conserved Domains (1) summary
      pfam15424
      Location:37265
      ODAM; Odontogenic ameloblast-associated family
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