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    BCAP29 B cell receptor associated protein 29 [ Homo sapiens (human) ]

    Gene ID: 55973, updated on 5-Jan-2022

    Summary

    Official Symbol
    BCAP29provided by HGNC
    Official Full Name
    B cell receptor associated protein 29provided by HGNC
    Primary source
    HGNC:HGNC:24131
    See related
    Ensembl:ENSG00000075790 MIM:619612
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    B29; BAP29
    Summary
    Involved in osteoblast differentiation. Located in membrane. [provided by Alliance of Genome Resources, Nov 2021]
    Expression
    Ubiquitous expression in thyroid (RPKM 19.4), testis (RPKM 16.0) and 24 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See BCAP29 in Genome Data Viewer
    Location:
    7q22.3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109.20211119 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (107580007..107623317)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (107220452..107263762)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene component of oligomeric golgi complex 5 Neighboring gene G protein-coupled receptor 22 Neighboring gene DUS4L-BCAP29 readthrough Neighboring gene dihydrouridine synthase 4 like Neighboring gene uncharacterized LOC105375443 Neighboring gene WBP1L pseudogene 2 Neighboring gene BANF1 pseudogene 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.
    EBI GWAS Catalog

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Readthrough DUS4L-BCAP29

    Readthrough gene: DUS4L-BCAP29, Included gene: DUS4L

    Homology

    Clone Names

    • FLJ53907, DKFZp686M2086

    General protein information

    Preferred Names
    B-cell receptor-associated protein 29
    Names
    BCR-associated protein 29

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008405.4NP_001008405.1  B-cell receptor-associated protein 29 isoform a

      See identical proteins and their annotated locations for NP_001008405.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (a).
      Source sequence(s)
      AC004839
      Consensus CDS
      CCDS34730.1
      UniProtKB/Swiss-Prot
      Q9UHQ4
      UniProtKB/TrEMBL
      E9PAJ1
      Related
      ENSP00000400718.2, ENST00000445771.6
      Conserved Domains (1) summary
      pfam05529
      Location:1220
      Bap31; B-cell receptor-associated protein 31-like
    2. NM_001363482.1NP_001350411.1  B-cell receptor-associated protein 29 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4), as well as variant 8, encodes isoform c.
      Source sequence(s)
      AC004839, AC078937
      Related
      ENSP00000419681.1, ENST00000491150.5
      Conserved Domains (3) summary
      PTZ00121
      Location:128271
      PTZ00121; MAEBL; Provisional
      pfam05529
      Location:1129
      Bap31; B-cell receptor-associated protein 31-like
      pfam18035
      Location:185234
      Bap31_Bap29_C; Bap31/Bap29 cytoplasmic coiled-coil domain
    3. NM_001363483.2NP_001350412.1  B-cell receptor-associated protein 29 isoform d

      Status: VALIDATED

      Source sequence(s)
      AC004839
      Conserved Domains (3) summary
      PTZ00121
      Location:128228
      PTZ00121; MAEBL; Provisional
      pfam05529
      Location:1129
      Bap31; B-cell receptor-associated protein 31-like
      pfam18035
      Location:185231
      Bap31_Bap29_C; Bap31/Bap29 cytoplasmic coiled-coil domain
    4. NM_001371353.1NP_001358282.1  B-cell receptor-associated protein 29 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6), as well as variants 2 and 7, encodes isoform b.
      Source sequence(s)
      AC004839
      Conserved Domains (2) summary
      pfam05529
      Location:1129
      Bap31; B-cell receptor-associated protein 31-like
      pfam18035
      Location:185239
      Bap31_Bap29_C; Bap31/Bap29 cytoplasmic coiled-coil domain
    5. NM_001371354.1NP_001358283.1  B-cell receptor-associated protein 29 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7), as well as variants 2 and 6, encodes isoform b.
      Source sequence(s)
      AC004839
      Conserved Domains (2) summary
      pfam05529
      Location:1129
      Bap31; B-cell receptor-associated protein 31-like
      pfam18035
      Location:185239
      Bap31_Bap29_C; Bap31/Bap29 cytoplasmic coiled-coil domain
    6. NM_001371355.1NP_001358284.1  B-cell receptor-associated protein 29 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8), as well as variant 4, encodes isoform c.
      Source sequence(s)
      AC004839, AC078937
      Conserved Domains (3) summary
      PTZ00121
      Location:128271
      PTZ00121; MAEBL; Provisional
      pfam05529
      Location:1129
      Bap31; B-cell receptor-associated protein 31-like
      pfam18035
      Location:185234
      Bap31_Bap29_C; Bap31/Bap29 cytoplasmic coiled-coil domain
    7. NM_001371356.1NP_001358285.1  B-cell receptor-associated protein 29 isoform e

      Status: VALIDATED

      Source sequence(s)
      AC004839
      Conserved Domains (2) summary
      TIGR03752
      Location:120198
      conj_TIGR03752; integrating conjugative element protein, PFL_4705 family
      pfam05529
      Location:1129
      Bap31; B-cell receptor-associated protein 31-like
    8. NM_001371357.1NP_001358286.1  B-cell receptor-associated protein 29 isoform f

      Status: VALIDATED

      Source sequence(s)
      AC004839, AC078937
      Related
      ENSP00000409350.1, ENST00000457837.5
      Conserved Domains (3) summary
      TIGR03752
      Location:120203
      conj_TIGR03752; integrating conjugative element protein, PFL_4705 family
      pfam05529
      Location:1129
      Bap31; B-cell receptor-associated protein 31-like
      pfam18035
      Location:185231
      Bap31_Bap29_C; Bap31/Bap29 cytoplasmic coiled-coil domain
    9. NM_018844.4NP_061332.2  B-cell receptor-associated protein 29 isoform b

      See identical proteins and their annotated locations for NP_061332.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, and lacks an alternate exon in the 3' coding region that causes a frameshift, compared to variant 1. The resulting isoform (b) is shorter and has a distinct C-terminus, compared to isoform a. Variants 2, 6, and 7 all encode the same isoform (b).
      Source sequence(s)
      AC004839
      Consensus CDS
      CCDS34731.1
      UniProtKB/Swiss-Prot
      Q9UHQ4
      UniProtKB/TrEMBL
      E9PAJ1
      Related
      ENSP00000005259.4, ENST00000005259.9
      Conserved Domains (2) summary
      pfam05529
      Location:1129
      Bap31; B-cell receptor-associated protein 31-like
      pfam18035
      Location:185239
      Bap31_Bap29_C; Bap31/Bap29 cytoplasmic coiled-coil domain

    RNA

    1. NR_027830.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' region and lacks an exon in the 3' region, compared to variant 1. This variant is represented as non-coding because it lacks a portion of the 5' coding region including the translational start codon, compared to variant 1, and there is uncertainty about its coding capacity.
      Source sequence(s)
      AC004839
    2. NR_163926.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004839, AC078937
    3. NR_163927.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004839, AC078937
    4. NR_163928.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004839
    5. NR_163929.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004839
    6. NR_163930.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004839
    7. NR_163931.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004839
    8. NR_163932.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004839
    9. NR_163933.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004839
    10. NR_163934.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004839
    11. NR_163935.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004839
    12. NR_163936.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004839
    13. NR_163937.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004839
    14. NR_163938.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004839

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

      Range
      107580007..107623317
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p13 PATCHES

    Genomic

    1. NW_017852930.1 Reference GRCh38.p13 PATCHES

      Range
      425662..468267
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001008406.1: Suppressed sequence

      Description
      NM_001008406.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    2. NM_001008407.1: Suppressed sequence

      Description
      NM_001008407.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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