Escherichia coli. This organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E.coli is easily grown in a laboratory setting and is readily amenable to genetic manipulation making it one of the most
More...studied prokaryotic model organisms. E.coli K-12 is the most widely studied strain of E. coli and serves as a reference for this species. E. coli is also one of the most diverse microbial species, containing both pathogenic and non-pathogenic strains. Pathogenic E. coli can cause urinary tract infections, neonatal meningitis, and many, often severe, intestinal diseases. Pathogenic strains often have virulence factors encoded on extrachromosomal plasmids or within bacteriophages and distinct DNA segments termed pathogenicity islands (PAIs). PAIs are likely to have been transferred horizontally and may even have integrated into the chromosome through bacteriophage or plasmid integration or transposition. These virulence factors have often been transferred from closely related, highly pathogenic, Shigella species. Among other virulence factors, enteroinvasive E. coli share an invasion plasmid with Shigella.Reference strains from the pathogenic E. coli are the urinary tract pathogens Escherichia coli IAI39 and Escherichia coli UMN026, Escherichia coli O157:H7 str. Sakai which causes hemorrhagic colitis, Escherichia coli O83:H1 str. NRG 857C which is implicated in Crohn's Disease, and Escherichia coli O104:H4 str. 2011C-3493 which cause hemolytic uremic syndrome. Less...- MuDoGeR: Multi-Domain Genome recovery from metagenomes made easy. Rocha U, et al. Mol Ecol Resour 2024 Feb
- Cross-contamination of carbapenem-resistant Gram-negative bacteria between patients and the hospital environment in the first year of a newly built surgical ward. Boutin S, et al. J Hosp Infect 2024 Feb
- Clinical, microbiological and genomic characterization of Gram-negative bacteria with dual carbapenemases as identified by rapid molecular testing. Mushtaq A, et al. JAC Antimicrob Resist 2024 Feb
- In-patient evolution of a high-persister Escherichia coli strain with reduced in vivo antibiotic susceptibility. Parsons JB, et al. Proc Natl Acad Sci U S A 2024 Jan 16
- Genomic and epidemiological insight of an outbreak of carbapenemase-producing Enterobacterales in a Portuguese hospital with the emergence of the new KPC-124. Manageiro V, et al. J Infect Public Health 2024 Mar
- Sequential Treatment Failure With Aztreonam-Ceftazidime-Avibactam Followed by Cefiderocol Due to Preexisting and Acquired Mechanisms in a New Delhi Metallo-β-lactamase-Producing Escherichia coli Causing Fatal Bloodstream Infection. Senchyna F, et al. Clin Infect Dis 2024 Jan 30
- Emergence of tet(X4)-positive Enterobacterales in retail eggs and the widespread of IncFIA(HI1)-HI1A-HI1B(R27) plasmids carrying tet(X4). Yue C, et al. Int J Food Microbiol 2024 Apr 2
- In Silico Analysis of Shiga Toxin-Producing Escherichia coli O157:H7 Strains from Presumptive Super- and Low-Shedder Cattle. Bumunang EW, et al. Toxins (Basel) 2024 Feb 5
- Resistance to critically important antibiotics in hospital wastewater from the largest Croatian city. Puljko A, et al. Sci Total Environ 2023 Apr 20
- Metagenome-assembled genomes indicate that antimicrobial resistance genes are highly prevalent among urban bacteria and multidrug and glycopeptide resistances are ubiquitous in most taxa. Magnúsdóttir S, et al. Front Microbiol 2023
- A neglected and emerging antimicrobial resistance gene encodes for a serine-dependent macrolide esterase. Dhindwal P, et al. Proc Natl Acad Sci U S A 2023 Feb 21
- Characterization of NDM-5-Producing Escherichia coli Strains Isolated from Pediatric Patients with Bloodstream Infections in a Chinese Hospital. Huang L, et al. Genes (Basel) 2023 Feb 18
- Genomic and clinical characteristics of carbapenem-resistant Enterobacter cloacae complex isolates collected in a Chinese tertiary hospital during 2013-2021. Han M, et al. Front Microbiol 2023
- Back to Basics: A Simplified Improvement to Multiple Displacement Amplification for Microbial Single-Cell Genomics. Sobol MS, et al. Int J Mol Sci 2023 Feb 21
- Distribution of Extremely Heat-Resistant Escherichia coli in the Beef Production and Processing Continuum. Guragain M, et al. J Food Prot 2023 Jan
- Virotyping and genetic antimicrobial susceptibility testing of porcine ETEC/STEC strains and associated plasmid types. Vereecke N, et al. Front Microbiol 2023
- Genome-Based Characterization of Hybrid Shiga Toxin-Producing and Enterotoxigenic Escherichia coli (STEC/ETEC) Strains Isolated in South Korea, 2016-2020. Lee W, et al. Microorganisms 2023 May 15
- Genomic dissection of endemic carbapenem resistance reveals metallo-beta-lactamase dissemination through clonal, plasmid and integron transfer. Macesic N, et al. Nat Commun 2023 Aug 8
- Zoonotic potential and antimicrobial resistance of Escherichia spp. in urban crows in Japan-first detection of E. marmotae and E. ruysiae. Sakaguchi K, et al. Comp Immunol Microbiol Infect Dis 2023 Sep
- A comprehensive genomic catalog from global cold seeps. Han Y, et al. Sci Data 2023 Sep 8
More...
Reference genomes: -
Escherichia coli str. K-12 substr. MG1655
Morphology: Gram:Negative, Shape:Bacilli, Motility:Yes Environment: OxygenReq:Facultative, OptimumTemperature:37, TemperatureRange:Mesophilic, Habitat:HostAssociated
Type
|
Name
|
RefSeq
|
INSDC
|
Size (Mb)
|
GC%
|
Protein
|
rRNA
|
tRNA
|
Other RNA
|
Gene
|
Pseudogene
|
---|
Chr | - | NC_000913.3 | U00096.3 | 4.64 | 50.8 | 4,298 | 22 | 86 | 99 | 4,639 | 145 | |
-
Escherichia coli O157:H7 str. Sakai
Morphology: Gram:Negative, Shape:Bacilli, Motility:Yes Environment: OxygenReq:Facultative, OptimumTemperature:37, TemperatureRange:Mesophilic, Habitat:HostAssociated Phenotype: Disease:Hemorrhagic colitis
|