Genome

Enterococcus faecium Commensal organism that can cause opportunistic infections Lineage: Bacteria[37515]; Bacillota[6135]; Bacilli[2619]; Lactobacillales[872]; Enterococcaceae[126]; Enterococcus[69]; Enterococcus faecium[1]

Enterococcus. This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both More...Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. Other Enterococcus species such as casseliflavus and gallinarum have also been implicated in opportunistic infections. Enterococcus faecium. This opportunistic pathogen causes a range of infections similar to those observed with Enterococcus faecalis, including urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart). Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains and has led to the rise of vancomycin-resistant Staphylococcus aureus strains due to the horizontal transfer of Enterococcus antibiotic resistance genes. Little is known about the virulence mechanisms in this organism, but the genome does encode an esp gene for the surface adhesin. Vancomycin resistant isolates are more typically Enterococcus faecium than Enterococcus faecalis. Less...

Summary Sequence data:  genome assemblies: 3665; sequence reads: 46  (See  Genome Assembly and Annotation report) Statistics:  median total length (Mb): 2.91162  median protein count: 2712  median GC%: 37.8014 Publications (limited to 20 most recent records) Clinical, microbiological and genomic characterization of Gram-negative bacteria with dual carbapenemases as identified by rapid molecular testing. Mushtaq A, et al. JAC Antimicrob Resist 2024 Feb Role of membrane vesicles in the transmission of vancomycin resistance in Enterococcus faecium. Lehmkuhl J, et al. Sci Rep 2024 Jan 22 Molecular identification and whole genome sequence analyses of methicillin-resistant and mastitis-associated Staphylococcus aureus sequence types 6 and 2454 isolated from dairy cows. Rahman MH, et al. J Genomics 2024 Draft genome sequences of Bacillus licheniformis strains MEZBL63 and MEZBL64 harboring the lichenysin toxin operon isolated from livestock in South Africa. El Zowalaty ME, et al. Microbiol Resour Announc 2024 Mar 12 Study of an Enterococcus faecium strain isolated from an artisanal Mexican cheese, whole-genome sequencing, comparative genomics, and bacteriocin expression. Acero-Pimentel D, et al. Antonie Van Leeuwenhoek 2024 Feb 23 Epidemiology and genetic diversity of linezolid-resistant Enterococcus clinical isolates in Belgium from 2013 to 2021. Mortelé O, et al. J Glob Antimicrob Resist 2024 May 7 Draft genome sequences of clinical mastitis-associated Enterococcus faecalis and Enterococcus faecium carrying multiple antimicrobial resistance genes isolated from dairy cows. Rahman MH, et al. J Glob Antimicrob Resist 2024 May 23 Draft genome sequences of rare Lelliottia nimipressuralis strain MEZLN61 and two Enterobacter kobei strains MEZEK193 and MEZEK194 carrying mobile colistin resistance gene mcr-9 isolated from wastewater in South Africa. El Zowalaty ME, et al. J Glob Antimicrob Resist 2023 Jun Top-Down Genomic Surveillance Approach To Investigate the Genomic Epidemiology and Antibiotic Resistance Patterns of Enterococcus faecium Detected in Cancer Patients in Arkansas. Udaondo Z, et al. Microbiol Spectr 2023 Jun 15 Prevalence of Enterococcus spp. and the Whole-Genome Characteristics of Enterococcus faecium and Enterococcus faecalis Strains Isolated from Free-Living Birds in Poland. Kwit R, et al. Pathogens 2023 Jun 16 Draft Genome Sequences of Two Clinical Mastitis-Associated Escherichia coli Strains, of Sequence Type 101 and Novel Sequence Type 13054, Isolated from Dairy Cows in Bangladesh. Rahman MH, et al. Microbiol Resour Announc 2023 Aug 22 Fiber supplementation protects from antibiotic-induced gut microbiome dysbiosis by modulating gut redox potential. Penumutchu S, et al. Nat Commun 2023 Aug 24 Impact of discontinuing contact precautions and enforcement of basic hygiene measures on nosocomial vancomycin-resistant Enterococcus faecium transmission. Eichel VM, et al. J Hosp Infect 2022 Mar The Mouse Gastrointestinal Bacteria Catalogue enables translation between the mouse and human gut microbiotas via functional mapping. Beresford-Jones BS, et al. Cell Host Microbe 2022 Jan 12 Population dynamics in colonizing vancomycin-resistant Enterococcus faecium isolated from immunosuppressed patients. Both A, et al. J Glob Antimicrob Resist 2022 Mar Whole genome sequence analyses-based assessment of virulence potential and antimicrobial susceptibilities and resistance of Enterococcus faecium strains isolated from commercial swine and cattle probiotic products. Shridhar PB, et al. J Anim Sci 2022 Mar 1 Contemporary Clinical and Molecular Epidemiology of Vancomycin-Resistant Enterococcal Bacteremia: A Prospective Multicenter Cohort Study (VENOUS I). Contreras GA, et al. Open Forum Infect Dis 2022 Mar Genomic Analysis of Multidrug-Resistant Enterococcus faecium Harboring vanA Gene from Wastewater Treatment Plants. Farias BO, et al. Microb Drug Resist 2022 Apr Draft Genome Sequence of Listeria innocua Strain MEZLIS29, Isolated from a Cow in South Africa. El Zowalaty ME, et al. Microbiol Resour Announc 2022 Mar 17 Draft genome sequence of Cronobacter sakazakii strain MEZCS99 sequence type 3 isolated from chicken in South Africa. El Zowalaty ME, et al. J Glob Antimicrob Resist 2022 Dec More...  Representative (genome information for reference and representative genomes) Reference genome:   Enterococcus faecium ASM973400v2 Submitter: Zhejiang University Type Name RefSeq INSDC Size (Mb) GC% Protein rRNA tRNA Other RNA Gene Pseudogene Chr - NZ_CP038996.1 CP038996.1 2.8 38.0 2,574 18 70 4 2,745 79 Plsm pSRR24 NZ_CP038997.1 CP038997.1 0.12 34.6 134 - - - 136 2 Dendrogram (based on genomic BLAST)