Genome

Pyricularia oryzae Fungus that causes rice blast disease Lineage: Eukaryota[15557]; Fungi[5220]; Dikarya[4853]; Ascomycota[3867]; Pezizomycotina[2638]; Sordariomycetes[1176]; Sordariomycetidae[272]; Magnaporthales[22]; Pyriculariaceae[7]; Pyricularia[6]; Pyricularia oryzae[1]

Magnaporthe oryzae (asexual state: Pyricularia oryzae), previously known as Magnaporthe grisea is a haploid filamentous ascomycete and the causal agent of rice blast disease. Strains isolated from Digitaria (eg. crabgrass and finger-grass) have been defined as M. grisea while isolates from rice and other hosts were More...named M. oryzae. These two groups have been separted based on clear genetic differences and lack of interbreeding. Rice blast disease is a major threat worldwide, destroying enough rice annually to feed more than 60 million people. Although resistant strains of rice have been developed, M. oryzae can rapidly evolve to overcome host resistance. M. oryzae is an ideal model organism for studying plant pathogenic fungi and host-parasite interactions for several reasons: it has a relatively small genome, making it amenable to whole genome analysis; extensive genetic mapping data is available; it is closely related to the widely studied non-pathogen Neurospora crassa, enabling comparative genomic studies; a draft sequence of the host (rice) genome has been completed; it can be cultured on defined media and has a well-established transformation system, facilitating biochemical and molecular analyses; and the early stages of its infection process can be experimentally studied. A full understanding of the molecular basis of fungal phytopathogenicity and host-parasite interactions will be instrumental for the development of novel environmentally sound strategies to protect world food supplies.The Magnaporthe oryzae genome is approximately 40 Mb, organized in 7 chromosomes. Less...

Summary Sequence data:  genome assemblies: 385; sequence reads: 10  (See  Genome Assembly and Annotation report) Statistics:  median total length (Mb): 40.2195  median protein count: 12330  median GC%: 50.9 Publications (limited to 20 most recent records) Emergence of a hybrid PKS-NRPS secondary metabolite cluster in a clonal population of the rice blast fungus Magnaporthe oryzae. Zhong Z, et al. Environ Microbiol 2020 Jul Genome Sequence Resource of Magnaporthe oryzae Laboratory Strain 2539. Chen M, et al. Mol Plant Microbe Interact 2020 Aug Gene Duplication and Mutation in the Emergence of a Novel Aggressive Allele of the AVR-Pik Effector in the Rice Blast Fungus. Longya A, et al. Mol Plant Microbe Interact 2019 Jun Blast Fungal Genomes Show Frequent Chromosomal Changes, Gene Gains and Losses, and Effector Gene Turnover. Gómez Luciano LB, et al. Mol Biol Evol 2019 Jun 1 Effector gene reshuffling involves dispensable mini-chromosomes in the wheat blast fungus. Peng Z, et al. PLoS Genet 2019 Sep Gene Flow between Divergent Cereal- and Grass-Specific Lineages of the Rice Blast Fungus Magnaporthe oryzae. Gladieux P, et al. mBio 2018 Feb 27 Population genomic analysis of the rice blast fungus reveals specific events associated with expansion of three main clades. Zhong Z, et al. ISME J 2018 Aug PacBio Sequencing Reveals Transposable Elements as a Key Contributor to Genomic Plasticity and Virulence Variation in Magnaporthe oryzae. Bao J, et al. Mol Plant 2017 Nov 6 Directional Selection from Host Plants Is a Major Force Driving Host Specificity in Magnaporthe Species. Zhong Z, et al. Sci Rep 2016 May 6 Analysis of Magnaporthe oryzae Genome Reveals a Fungal Effector, Which Is Able to Induce Resistance Response in Transgenic Rice Line Containing Resistance Gene, Pi54. Ray S, et al. Front Plant Sci 2016 Genome-Wide Comparison of Magnaporthe Species Reveals a Host-Specific Pattern of Secretory Proteins and Transposable Elements. Shirke MD, et al. PLoS One 2016 Global genome and transcriptome analyses of Magnaporthe oryzae epidemic isolate 98-06 uncover novel effectors and pathogenicity-related genes, revealing gene gain and lose dynamics in genome evolution. Dong Y, et al. PLoS Pathog 2015 Apr Genome comparison of two Magnaporthe oryzae field isolates reveals genome variations and potential virulence effectors. Chen C, et al. BMC Genomics 2013 Dec 16 Comparative analysis of the genomes of two field isolates of the rice blast fungus Magnaporthe oryzae. Xue M, et al. PLoS Genet 2012 The genome sequence of the rice blast fungus Magnaporthe grisea. Dean RA, et al. Nature 2005 Apr 21 More...  Representative (genome information for reference and representative genomes) Reference genome:   Pyricularia oryzae 70-15 Submitter: International Rice Blast Genome Consortium Loc Type Name RefSeq INSDC Size (Mb) GC% Protein rRNA tRNA Other RNA Gene Pseudogene Chr 1 NC_017844.1 CM001231.1 7.98 51.2 2,478 3 67 - 2,513 34 Chr 2 NC_017850.1 CM001232.1 8.32 51.8 2,615 6 48 - 2,627 20 Chr 3 NC_017849.1 CM001233.1 6.61 51.6 2,102 8 59 - 2,149 24 Chr 4 NC_017851.1 CM001234.1 5.55 51.8 1,795 6 50 - 1,830 15 Chr 5 NC_017852.1 CM001235.1 4.49 51.9 1,470 8 35 - 1,498 13 Chr 6 NC_017853.1 CM001236.1 4.13 51.6 1,313 2 30 - 1,328 14 Chr 7 NC_017854.1 CM001237.1 3.42 51.3 1,063 7 30 - 1,087 11 Un - . - 0.49 50.8 153 - - - 152 - Chromosomes Click on chromosome name to open Genome Data Viewer External Resources MGOS Community Annotation Database Fungal Genetics Stock Center DFCI M. grisea Gene Index