Genome

Canis lupus familiaris (dog) dog Lineage: Eukaryota[15557]; Metazoa[7782]; Chordata[3579]; Craniata[3544]; Vertebrata[3544]; Euteleostomi[3500]; Mammalia[873]; Eutheria[699]; Laurasiatheria[340]; Carnivora[89]; Caniformia[58]; Canidae[14]; Canis[4]; Canis lupus[3]; Canis lupus familiaris[1]

The dog, Canis lupus familiaris, is a useful model organism for medical research due to extensive genetic diversity and morphological variation within the species and to aggressive breeding practices that have resulted in inbred populations of dogs. Many breeds of dog are particularly susceptible to inherited diseases that are also common in More...humans, such as cancer, heart disease, rheumatoid arthritis, autoimmune disorders, deafness, and blindness. The size of the haploid dog genome is estimated to be 2445 Mb. The diploid genome is organized in 38 pairs of autosomes and two sex chromosomes. Less...

Summary Sequence data:  genome assemblies: 23; sequence reads: 32  (See  Genome Assembly and Annotation report) Statistics:  median total length (Mb): 2343.81  median protein count: 64557  median GC%: 41.212 NCBI Annotation Release:  106 Publications (limited to 20 most recent records) Canfam_GSD: De novo chromosome-length genome assembly of the German Shepherd Dog (Canis lupus familiaris) using a combination of long reads, optical mapping, and Hi-C. Field MA, et al. Gigascience 2020 Apr 1 Stochastic anomaly of methylome but persistent SRY hypermethylation in disorder of sex development in canine somatic cell nuclear transfer. Jeong YH, et al. Sci Rep 2016 Aug 9 Genome sequence, comparative analysis and haplotype structure of the domestic dog. Lindblad-Toh K, et al. Nature 2005 Dec 8 5-HT7 receptor efficacy distribution throughout the canine stomach. Janssen P, et al. Br J Pharmacol 2004 Oct The dog genome: survey sequencing and comparative analysis. Kirkness EF, et al. Science 2003 Sep 26 The complete nucleotide sequence of the domestic dog (Canis familiaris) mitochondrial genome. Kim KS, et al. Mol Phylogenet Evol 1998 Oct More...  Representative (genome information for reference and representative genomes) Reference genome:   Canis lupus familiaris UU_Cfam_GSD_1.0 Submitter: Uppsala University Loc Type Name RefSeq INSDC Size (Mb) GC% Chr 1 - CM021962.1 123.56 41.7 Chr 2 - CM021963.1 84.98 43.0 Chr 3 - CM021964.1 92.48 40.4 Chr 4 - CM021965.1 89.54 40.4 Chr 5 - CM021966.1 89.56 44.3 Chr 6 - CM021967.1 78.11 42.7 Chr 7 - CM021968.1 81.08 41.0 Chr 8 - CM021969.1 76.41 40.7 Chr 9 - CM021970.1 61.17 46.3 Chr 10 - CM021971.1 70.64 42.8 Chr 11 - CM021972.1 74.81 40.3 Chr 12 - CM021973.1 72.97 39.0 Chr 13 - CM021974.1 64.3 40.2 Chr 14 - CM021975.1 61.11 38.8 Chr 15 - CM021976.1 64.68 40.3 Chr 16 - CM021977.1 60.36 41.1 Chr 17 - CM021978.1 65.09 41.8 Chr 18 - CM021979.1 56.47 42.9 Chr 19 - CM021980.1 55.52 38.5 Chr 20 - CM021981.1 58.63 44.5 Chr 21 - CM021982.1 51.74 40.2 Chr 22 - CM021983.1 61.57 38.0 Chr 23 - CM021984.1 53.14 40.0 Chr 24 - CM021985.1 48.57 44.6 Chr 25 - CM021986.1 51.73 41.4 Chr 26 - CM021987.1 39.26 45.5 Chr 27 - CM021988.1 46.66 40.2 Chr 28 - CM021989.1 41.73 43.7 Chr 29 - CM021990.1 42.52 38.3 Chr 30 - CM021991.1 40.64 41.5 Chr 31 - CM021992.1 39.9 39.6 Chr 32 - CM021993.1 40.23 37.4 Chr 33 - CM021994.1 32.14 39.3 Chr 34 - CM021995.1 42.4 40.5 Chr 35 - CM021996.1 28.05 41.8 Chr 36 - CM021997.1 31.22 38.7 Chr 37 - CM021998.1 30.79 40.3 Chr 38 - CM021999.1 24.8 41.2 Chr X - CM022000.1 124.99 40.3 MT - CM022001.1 0.02 39.7 Un - . - 128.44 47.1 Chromosomes Click on chromosome name to open Genome Data Viewer External Resources Animal Health Trust Dog DNA Testing Canine BAC Library Canine Genetic Linkage Map Canine Sequencing White Paper Cytogenetics and Canine Cancer, NC State DFCI Gene Index Dog Genome Sequencing Project - Broad Dog Olfactory Receptors NHGRI Dog Genome Project NISC Comparative Vertebrate Sequencing Online Mendelian Inheritance in Animals The Canine Radiation Hybrid Project The FHCRC Dog Genome Project