Escherichia coli. This organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E.coli is easily grown in a laboratory setting and is readily amenable to genetic manipulation making it one of the most
More...studied prokaryotic model organisms. E.coli K-12 is the most widely studied strain of E. coli and serves as a reference for this species. E. coli is also one of the most diverse microbial species, containing both pathogenic and non-pathogenic strains. Pathogenic E. coli can cause urinary tract infections, neonatal meningitis, and many, often severe, intestinal diseases. Pathogenic strains often have virulence factors encoded on extrachromosomal plasmids or within bacteriophages and distinct DNA segments termed pathogenicity islands (PAIs). PAIs are likely to have been transferred horizontally and may even have integrated into the chromosome through bacteriophage or plasmid integration or transposition. These virulence factors have often been transferred from closely related, highly pathogenic, Shigella species. Among other virulence factors, enteroinvasive E. coli share an invasion plasmid with Shigella.Reference strains from the pathogenic E. coli are the urinary tract pathogens Escherichia coli IAI39 and Escherichia coli UMN026, Escherichia coli O157:H7 str. Sakai which causes hemorrhagic colitis, Escherichia coli O83:H1 str. NRG 857C which is implicated in Crohn's Disease, and Escherichia coli O104:H4 str. 2011C-3493 which cause hemolytic uremic syndrome. Less...- Widespread prevalence and molecular epidemiology of tet(X4) and mcr-1 harboring Escherichia coli isolated from chickens in Pakistan. Li R, et al. Sci Total Environ 2022 Feb 1
- Characterization of a carbapenem-resistant Escherichia coli from dairy cattle harbouring blaNDM-1 in an IncC plasmid. Tello M, et al. J Antimicrob Chemother 2022 Feb 23
- Pathogenicity of Shiga toxin-producing Escherichia coli (STEC) from wildlife: Should we care? Dias D, et al. Sci Total Environ 2022 Mar 15
- Interleukin-1β secretion induced by mucosa-associated gut commensal bacteria promotes intestinal barrier repair. Wu WH, et al. Gut Microbes 2022 Jan-Dec
- Intracellular Transposition and Capture of Mobile Genetic Elements following Intercellular Conjugation of Multidrug Resistance Conjugative Plasmids from Clinical Enterobacteriaceae Isolates. Tansirichaiya S, et al. Microbiol Spectr 2022 Feb 23
- Complete sequence of classic F-type plasmid pRK100 shows unique conservation over time and geographic location. Starčič Erjavec M, et al. Plasmid 2022 Jan-Mar
- High-resolution genomic surveillance elucidates a multilayered hierarchical transfer of resistance between WWTP- and human/animal-associated bacteria. Che Y, et al. Microbiome 2022 Jan 25
- Genomic features of a multidrug-resistant and mercury-tolerant environmental Escherichia coli recovered after a mining dam disaster in South America. Gaeta NC, et al. Sci Total Environ 2022 Jun 1
- Single-cell genomics for resolution of conserved bacterial genes and mobile genetic elements of the human intestinal microbiota using flow cytometry. Lawrence D, et al. Gut Microbes 2022 Jan-Dec
- A Natural Novel Mutation in the blaNDM-5 Promoter Reducing Carbapenems Resistance in a Clinical Escherichia coli Strain. Li Y, et al. Microbiol Spectr 2022 Feb 23
- Multicenter Evaluation of the Acuitas AMR Gene Panel for Detection of an Extended Panel of Antimicrobial Resistance Genes among Bacterial Isolates. Simner PJ, et al. J Clin Microbiol 2022 Mar 16
- Isolation and Characterization of Novel Lytic Phages Infecting Multidrug-Resistant Escherichia coli. Vera-Mansilla J, et al. Microbiol Spectr 2022 Feb 23
- Prevalence and antimicrobial susceptibility of CTX-M-type-producing Escherichia coli from a wildlife zoo in China. Zeng Z, et al. Vet Med Sci 2022 May
- Prevalence and Profiles of Antibiotic Resistance Genes mph(A) and qnrB in Extended-Spectrum Beta-Lactamase (ESBL)-Producing Escherichia coli Isolated from Dairy Calf Feces. Carey AM, et al. Microorganisms 2022 Feb 10
- The Use of Long-Read Sequencing Technologies in Infection Control: Horizontal Transfer of a blaCTX-M-27 Containing lncFII Plasmid in a Patient Screening Sample. van Almsick V, et al. Microorganisms 2022 Feb 23
- Characterization of Escherichia coli harboring colibactin genes (clb) isolated from beef production and processing systems. Guragain M, et al. Sci Rep 2022 Mar 29
- Occurrence and transfer characteristics of blaCTX-M genes among Escherichia coli in anaerobic digestion systems treating swine waste. Tian T, et al. Sci Total Environ 2022 Aug 15
- High Carriage of Extended-Spectrum, Beta Lactamase-Producing, and Colistin-Resistant Enterobacteriaceae in Tibetan Outpatients with Diarrhea. Li Z, et al. Antibiotics (Basel) 2022 Apr 11
- Efficacy of passive immunization in broiler chicks via an inactivated Escherichia coli autogenous vaccine administered to broiler breeder hens. Keita A, et al. Avian Pathol 2022 May 30
- Clonal relationship of tet(X4)-positive Escherichia coli ST761 isolates between animals and humans. Zhai W, et al. J Antimicrob Chemother 2022 Jun 9
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Reference genomes:  
Escherichia coli str. K-12 substr. MG1655Morphology: Gram:Negative, Shape:Bacilli, Motility:Yes Environment: OxygenReq:Facultative, OptimumTemperature:37, TemperatureRange:Mesophilic, Habitat:HostAssociated |
Type
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Name
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RefSeq
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INSDC
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Size (Mb)
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GC%
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Protein
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rRNA
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tRNA
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Other RNA
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Gene
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Pseudogene
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| Chr | - | NC_000913.3 | U00096.3 | 4.64 | 50.8 | 4,298 | 22 | 86 | 99 | 4,639 | 145 | |
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Escherichia coli O157:H7 str. Sakai
Morphology: Gram:Negative, Shape:Bacilli, Motility:Yes Environment: OxygenReq:Facultative, OptimumTemperature:37, TemperatureRange:Mesophilic, Habitat:HostAssociated Phenotype: Disease:Hemorrhagic colitis
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