Genome

Mycobacterium avium Environmental organism which causes infections in birds and humans Lineage: Bacteria[37515]; Actinomycetota[4918]; Actinomycetes[4472]; Mycobacteriales[730]; Mycobacteriaceae[256]; Mycobacterium[118]; Mycobacterium avium complex (MAC)[14]; Mycobacterium avium[1]

Mycobacterium. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, Mycobacteria have unusually high More...genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium avium. This taxon comprises different species, serovars and morphologic forms that vary in virulence. Mycobacterium avium is ubiquitous in the environment, and can be found in stagnant waters and soils. This organism causes tuberculosis in birds and disseminated infections in immunocompromized humans (the elderly, children, and especially patients with AIDS). Infection results in a characteristic pulmonary disease which requires expensive drug therapy for successful treatment. Most prevalent colony morphotypes are smooth opaque, smooth transparent and rough, with the last two being the faster growers in vivo. All three morphotypes are interchangeable and can persist in the lung. Colony morphology correlates with the presence of specific glycopeptidolipids (GPL) responsible for serotyping differences. Less...

Summary Sequence data:  genome assemblies: 290; sequence reads: 9  (See  Genome Assembly and Annotation report) Statistics:  median total length (Mb): 5.16748  median protein count: 4736  median GC%: 69.1 Publications (limited to 20 most recent records) Complete genome assembly of Hawai'i environmental nontuberculous mycobacteria reveals unexpected co-isolation with methylobacteria. Hendrix J, et al. PLoS One 2023 Genotypic analysis of nontuberculous mycobacteria isolated from raw milk and human cases in Wisconsin. Ali ZI, et al. J Dairy Sci 2021 Jan Direct PCR on Tissue Samples To Detect Mycobacterium tuberculosis Complex: an Alternative to the Bacteriological Culture. Lorente-Leal V, et al. J Clin Microbiol 2021 Jan 21 Complete Genome Sequence of a Type III Ovine Strain of Mycobacterium avium subsp. paratuberculosis. Bannantine JP, et al. Microbiol Resour Announc 2021 Mar 11 Complete Genome Sequence of Mycobacterium avium subsp. paratuberculosis Strain 42-13-1, Isolated in Japan. Ueno Y, et al. Microbiol Resour Announc 2021 Apr 15 Draft Genome Sequences of Two Bison-Type and Two Sheep-Type Strains of Mycobacterium avium subsp. paratuberculosis. Bannantine JP, et al. Microbiol Resour Announc 2021 Jul 15 Complete Genome Sequence and Manual Reannotation of Mycobacterium avium subsp. paratuberculosis Strain DSM 44135. Goethe R, et al. Microbiol Resour Announc 2020 Aug 13 Complete Genome Sequence of Ovine Mycobacterium avium subsp. paratuberculosis Strain JIII-386 (MAP-S/type III) and Its Comparison to MAP-S/type I, MAP-C, and M. avium Complex Genomes. Wibberg D, et al. Microorganisms 2020 Dec 29 FDA-ARGOS is a database with public quality-controlled reference genomes for diagnostic use and regulatory science. Sichtig H, et al. Nat Commun 2019 Jul 25 Environmental Mycobacterium avium subsp. hominissuis have a higher probability to act as a recipient in conjugation than clinical strains. Shoulah SA, et al. Plasmid 2018 Jan Comparative genome analyses of Mycobacterium avium reveal genomic features of its subspecies and strains that cause progression of pulmonary disease. Uchiya KI, et al. Sci Rep 2017 Jan 3 Complete Genome Sequence of Mycobacterium avium subsp. hominissuis Strain H87 Isolated from an Indoor Water Sample. Zhao X, et al. Genome Announc 2017 Apr 20 Draft Genome Sequence of Mycobacterium abscessus Bamboo. Yee M, et al. Genome Announc 2017 May 18 Draft Genome Sequence of Mycobacterium avium 11. Yee M, et al. Genome Announc 2017 Aug 10 Population Structure and Local Adaptation of MAC Lung Disease Agent Mycobacterium avium subsp. hominissuis. Yano H, et al. Genome Biol Evol 2017 Sep 1 Draft Genome Sequence of a Rare Pigmented Mycobacterium avium subsp. paratuberculosis Type C Strain. Barbosa P, et al. Genome Announc 2017 Oct 12 Genotyping and strain distribution of Mycobacterium avium subspecies hominissuis isolated from humans and pigs in Belgium, 2011-2013. Vluggen C, et al. Euro Surveill 2016 The isolation and molecular characterization of Mycobacterium avium subsp. paratuberculosis in Shandong province, China. Yue R, et al. Gut Pathog 2016 Complete Genome Sequence of Mycobacterium abscessus subsp. bolletii. Caverly LJ, et al. Genome Announc 2016 Jun 9 Characterization of a novel plasmid, pMAH135, from Mycobacterium avium subsp. hominissuis. Uchiya K, et al. PLoS One 2015 More...  Representative (genome information for reference and representative genomes) Reference genome:   Mycobacterium avium subsp. hominissuis Submitter: Kobe Institute of Health Type Name RefSeq INSDC Size (Mb) GC% Protein rRNA tRNA Other RNA Gene Pseudogene Chr - NZ_CP018019.1 CP018019.1 5.12 69.0 4,646 3 47 3 4,826 127 Dendrogram (based on genomic BLAST)